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Volumn 14, Issue 3, 2013, Pages 168-173

The metabolic effects of drugs used for the treatment of polycystic ovary syndrome;Polikistik over sendromu tedavisinde kullanılan ilaçların metabolik etkileri

Author keywords

Drug effects; Metabolic parameter; Polycystic ovary syndrome; Treatment

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; C REACTIVE PROTEIN; CHOLESTEROL; CYPROTERONE ACETATE PLUS ETHINYLESTRADIOL; DESOGESTREL PLUS ETHINYLESTRADIOL; DROSPIRENONE PLUS ETHINYLESTRADIOL; FATTY ACID; FINASTERIDE; FLUTAMIDE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; METFORMIN; ORAL CONTRACEPTIVE AGENT; PLACEBO; PRASTERONE SULFATE; PROLACTIN; ROSIGLITAZONE; SEX HORMONE BINDING GLOBULIN; SPIRONOLACTONE; TESTOSTERONE; TRIACYLGLYCEROL;

EID: 84883337175     PISSN: 13090399     EISSN: 13090380     Source Type: Journal    
DOI: 10.5152/jtgga.2013.57701     Document Type: Review
Times cited : (2)

References (52)
  • 2
    • 0344286476 scopus 로고    scopus 로고
    • Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
    • Ehrmann DA, Bames RB, Rosenfild RL, Cavaghan MK, Imperial J. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 1999; 22: 141-6.
    • (1999) Diabetes Care , vol.22 , pp. 141-146
    • Ehrmann, D.A.1    Bames, R.B.2    Rosenfild, R.L.3    Cavaghan, M.K.4    Imperial, J.5
  • 3
    • 4043104723 scopus 로고    scopus 로고
    • The cardiovascular risk of young women with polycystic ovary syndrome: An observational, analytical, prospective casecontrol study
    • Orio F Jr, Palomba S, Spinelli L, Cascella T, Tauchmanova L, Zullo F, et al. The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective casecontrol study. J Clin Endocrinol Metab 2004; 89; 3696-701.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3696-3701
    • Orio Jr., F.1    Palomba, S.2    Spinelli, L.3    Cascella, T.4    Tauchmanova, L.5    Zullo, F.6
  • 4
    • 0001698606 scopus 로고
    • Amenorrhea associated with bilateral polycystic ovaries
    • Stein IF, Leventhal NL. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol 1935; 29: 181-91.
    • (1935) Am J Obstet Gynecol , vol.29 , pp. 181-191
    • Stein, I.F.1    Leventhal, N.L.2
  • 5
    • 4544286633 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and longterm health risks related to polycystic ovary syndrome
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and longterm health risks related to polycystic ovary syndrome. Fertil Steril 2003; 81: 19-25.
    • (2003) Fertil Steril , vol.81 , pp. 19-25
  • 8
    • 0028044645 scopus 로고
    • The prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women
    • Farquhar CM, Birdsall M, Manning P, Mitchell JM, France JT. The prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women. Aust NZ J Obstet Gynecol 1994; 34: 67-72.
    • (1994) Aust NZ J Obstet Gynecol , vol.34 , pp. 67-72
    • Farquhar, C.M.1    Birdsall, M.2    Manning, P.3    Mitchell, J.M.4    France, J.T.5
  • 10
    • 0031773509 scopus 로고    scopus 로고
    • Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: A prospective study
    • Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998; 83: 3078-82.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3078-3082
    • Knochenhauer, E.S.1    Key, T.J.2    Kahsar-Miller, M.3    Waggoner, W.4    Boots, L.R.5    Azziz, R.6
  • 11
    • 0038369147 scopus 로고    scopus 로고
    • Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome
    • Yildiz BO, Yarali H, Oguz H, Bayraktar M. Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003; 88: 2031-6.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2031-2036
    • Yildiz, B.O.1    Yarali, H.2    Oguz, H.3    Bayraktar, M.4
  • 12
    • 0035145232 scopus 로고    scopus 로고
    • Polycystic ovarian disease: Heritability and heterogeneity
    • Crosignani PG, Nicolosi AE. Polycystic ovarian disease: heritability and heterogeneity. Hum Reprod Update 2001; 7: 3-7.
    • (2001) Hum Reprod Update , vol.7 , pp. 3-7
    • Crosignani, P.G.1    Nicolosi, A.E.2
  • 16
    • 0033022325 scopus 로고    scopus 로고
    • Ovarian and adrenal function in polycystic ovary syndrome
    • Rosenfield RL. Ovarian and adrenal function in polycystic ovary syndrome. Endocrinol Metab Clin North Am 1999; 28: 265-93.
    • (1999) Endocrinol Metab Clin North Am , vol.28 , pp. 265-293
    • Rosenfield, R.L.1
  • 17
    • 0033304623 scopus 로고    scopus 로고
    • Augmented and rogen production is a stable steroidogenic phenotype of propagated the ca cells from polycystic ovaries
    • Nelson VL, Legro RS, Strauss JF 3rd, McAllister JM. Augmented and rogen production is a stable steroidogenic phenotype of propagated the ca cells from polycystic ovaries. Mol Endocrinol 1999; 13: 946-57.
    • (1999) Mol Endocrinol , vol.13 , pp. 946-957
    • Nelson, V.L.1    Legro, R.S.2    Strauss III, J.F.3    McAllister, J.M.4
  • 18
    • 0034858480 scopus 로고    scopus 로고
    • Polycystic ovary syndrome and insulin-resistant hyperinsulinemia
    • Rosenfield RL. Polycystic ovary syndrome and insulin-resistant hyperinsulinemia. J Am Acad Dermatol 2001; 45: S95.
    • (2001) J Am Acad Dermatol , vol.45
    • Rosenfield, R.L.1
  • 19
    • 58149383818 scopus 로고    scopus 로고
    • Polycystic ovary syndrome is associated with tissue-specific differences in insulin resistance
    • Ciaraldi TP, Aroda V, Mudaliar S, Chang RJ, Henry RR. Polycystic ovary syndrome is associated with tissue-specific differences in insulin resistance. J Clin Endocrinol Metab 2009; 94: 157-63.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 157-163
    • Ciaraldi, T.P.1    Aroda, V.2    Mudaliar, S.3    Chang, R.J.4    Henry, R.R.5
  • 20
    • 32544457993 scopus 로고    scopus 로고
    • Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing and rogen levels independent of obesity and insulin resistance
    • Coviello AD, Legro RS, Dunaif A. Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing and rogen levels independent of obesity and insulin resistance. J Clin Endocrinol Metab 2006; 91: 492-7.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 492-497
    • Coviello, A.D.1    Legro, R.S.2    Dunaif, A.3
  • 22
    • 57349132982 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome and related characteristics in obese adolescents with and without polycystic ovary syndrome
    • Rossi B, Sukalich S, Droz J, Griffin A, Cook S, Blumkin A, et al. Prevalence of metabolic syndrome and related characteristics in obese adolescents with and without polycystic ovary syndrome. J Clin Endocrinol Metab 2008; 93: 4780-6.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4780-4786
    • Rossi, B.1    Sukalich, S.2    Droz, J.3    Griffin, A.4    Cook, S.5    Blumkin, A.6
  • 23
    • 17844367331 scopus 로고    scopus 로고
    • Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
    • Apridonidze T, Essah PA, Iuorno MJ, Nestler JE. Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2005; 90: 1929-35.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1929-1935
    • Apridonidze, T.1    Essah, P.A.2    Iuorno, M.J.3    Nestler, J.E.4
  • 24
    • 0344286476 scopus 로고    scopus 로고
    • Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
    • Ehrmann DA, Barnes RB, Rosenfield RL, Cavaghan MK, Imperial J. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 1999; 22: 141-6.
    • (1999) Diabetes Care , vol.22 , pp. 141-146
    • Ehrmann, D.A.1    Barnes, R.B.2    Rosenfield, R.L.3    Cavaghan, M.K.4    Imperial, J.5
  • 25
    • 0035093251 scopus 로고    scopus 로고
    • Polycystic ovary syndrome is associated with obstructive sleep apnea and day time sleepiness: Role of insulin resistance
    • Vgontzas AN, Legro RS, Bixler EO, Grayev A, Kales A, Chrousos GP. Polycystic ovary syndrome is associated with obstructive sleep apnea and day time sleepiness: role of insulin resistance. J Clin Endocrinol Metab 2001; 86: 517-20.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 517-520
    • Vgontzas, A.N.1    Legro, R.S.2    Bixler, E.O.3    Grayev, A.4    Kales, A.5    Chrousos, G.P.6
  • 26
    • 0038440516 scopus 로고    scopus 로고
    • Polycystic ovary syndrome and endometrial carcinoma
    • Hardiman P, Pillay OS, Atiomo W. Polycystic ovary syndrome and endometrial carcinoma. Lancet 2003; 361: 1810-2.
    • (2003) Lancet , vol.361 , pp. 1810-1812
    • Hardiman, P.1    Pillay, O.S.2    Atiomo, W.3
  • 27
    • 0038307320 scopus 로고    scopus 로고
    • Polycystic ovary syndrome and cardiovascular disease: A premature association
    • Legro RS. Polycystic ovary syndrome and cardiovascular disease: A premature association. Endocr Rev 2003; 24: 302-12.
    • (2003) Endocr Rev , vol.24 , pp. 302-312
    • Legro, R.S.1
  • 28
    • 34247590999 scopus 로고    scopus 로고
    • Searching for polycystic ovary syndrome in postmenopausal women: Evidence of a dose-effect association with prevalent cardiovascular disease
    • Krentz AJ, von Muhlen D, Barrett-Connor E. Searching for polycystic ovary syndrome in postmenopausal women: evidence of a dose-effect association with prevalent cardiovascular disease. Menopause 2007; 14: 284-92.
    • (2007) Menopause , vol.14 , pp. 284-292
    • Krentz, A.J.1    von Muhlen, D.2    Barrett-Connor, E.3
  • 29
    • 42049083794 scopus 로고    scopus 로고
    • Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: Results from the National Institutes of Health-National Heart, Lung, and Blood Institute sponsored Women's Ischemia Syndrome Evaluation
    • Shaw LJ, Bairey Merz CN, Azziz R, Stanczyk FZ, Sopko G, Braunstein GD, et al. Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health-National Heart, Lung, and Blood Institute sponsored Women's Ischemia Syndrome Evaluation. J Clin Endocrinol Metab 2008; 93: 1276-84.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1276-1284
    • Shaw, L.J.1    Bairey Merz, C.N.2    Azziz, R.3    Stanczyk, F.Z.4    Sopko, G.5    Braunstein, G.D.6
  • 30
    • 0028141408 scopus 로고
    • Serum lipoprotein lipid profile in women with the polycystic ovary syndrome: Relation to anthropometric, endocrine and metabolic variables
    • Holte J, Bergh T, Berne C, Lithell H. Serum lipoprotein lipid profile in women with the polycystic ovary syndrome: relation to anthropometric, endocrine and metabolic variables. Clin Endocrinol (Oxf) 1994; 41: 463-71.
    • (1994) Clin Endocrinol (Oxf) , vol.41 , pp. 463-471
    • Holte, J.1    Bergh, T.2    Berne, C.3    Lithell, H.4
  • 35
    • 84866899568 scopus 로고    scopus 로고
    • Hirsutism and polycystic ovary syndrome
    • In: Lifshitz F, ed., New York: Informa Healthcare USA Inc
    • Witchel SF. Hirsutism and polycystic ovary syndrome In: Lifshitz F, ed. Pediatric Endocrinology. New York: Informa Healthcare USA Inc; 2007. p.325-48.
    • (2007) Pediatric Endocrinology , pp. 325-348
    • Witchel, S.F.1
  • 36
    • 0028140279 scopus 로고
    • Comparison of flutamide and spironolactone in the treatment of hirsutism: A randomized controlled trial
    • Cusan L, Dupont A, Gomez JL, Tremblay RR, Labrie F. Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial. Fertil Steril 1994; 61: 281-7.
    • (1994) Fertil Steril , vol.61 , pp. 281-287
    • Cusan, L.1    Dupont, A.2    Gomez, J.L.3    Tremblay, R.R.4    Labrie, F.5
  • 37
    • 0034892698 scopus 로고    scopus 로고
    • Metformin directly inhibits androgen production in human thecal cells
    • Attia GR, Rainey WE, Carr BR. Metformin directly inhibits androgen production in human thecal cells. Fertil Steril 2001; 76: 517-24.
    • (2001) Fertil Steril , vol.76 , pp. 517-524
    • Attia, G.R.1    Rainey, W.E.2    Carr, B.R.3
  • 38
    • 5444275864 scopus 로고    scopus 로고
    • Recent advances in the treatment of polycystic ovary syndrome
    • Yildiz BO. Recent advances in the treatment of polycystic ovary syndrome. Expert Opin Investig Drugs 2004; 13: 1295-305.
    • (2004) Expert Opin Investig Drugs , vol.13 , pp. 1295-1305
    • Yildiz, B.O.1
  • 39
    • 0033710083 scopus 로고    scopus 로고
    • Endocrine and metabolic effects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: A randomized study
    • Morin-Papunen LC, Vauhkonen I, Koivunen RM, Ruokonen A, Martikainen HK, Tapanainen JS. Endocrine and metabolic effects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: a randomized study. J Clin Endocrinol Metab 2000; 85: 3161-8.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3161-3168
    • Morin-Papunen, L.C.1    Vauhkonen, I.2    Koivunen, R.M.3    Ruokonen, A.4    Martikainen, H.K.5    Tapanainen, J.S.6
  • 40
    • 0036253418 scopus 로고    scopus 로고
    • Androgen and lipid profiles in adolescents with polycystic ovary syndrome whowere treated with two forms of combined oral contraceptives
    • Mastorakos G, Koliopoulos C, Creatsas G. Androgen and lipid profiles in adolescents with polycystic ovary syndrome whowere treated with two forms of combined oral contraceptives. Fertil Steril 2002; 77: 919-27.
    • (2002) Fertil Steril , vol.77 , pp. 919-927
    • Mastorakos, G.1    Koliopoulos, C.2    Creatsas, G.3
  • 41
    • 31644449390 scopus 로고    scopus 로고
    • Effects of two forms of combined oral contraceptives on carbonhydrate metabolism in adolescents with polycystic ovary syndrome
    • Mastorakos G, Koliopoulos C, Deligeoroglou E, Diamanti-Kandarakis E, Creatsas G. Effects of two forms of combined oral contraceptives on carbonhydrate metabolism in adolescents with polycystic ovary syndrome. Fertil Steril 2006; 85: 420-7.
    • (2006) Fertil Steril , vol.85 , pp. 420-427
    • Mastorakos, G.1    Koliopoulos, C.2    Deligeoroglou, E.3    Diamanti-Kandarakis, E.4    Creatsas, G.5
  • 42
    • 34249665044 scopus 로고    scopus 로고
    • Effect of 6-month treatment with oral antiandrogen alone and in combination with insulin sensitizers on body composition, hormonal and metabolic parameters in women with polycystic ovary syndrome (PCOS) in order to determine therapeutic strategy
    • Orbetsova M, Kamenov Z, Kolarov G, Zakharieva S, Khristov V, Atanasova I, et al. Effect of 6-month treatment with oral antiandrogen alone and in combination with insulin sensitizers on body composition, hormonal and metabolic parameters in women with polycystic ovary syndrome (PCOS) in order to determine therapeutic strategy. Akush Ginekol (Sofiia) 2006; 45: 16-28.
    • (2006) Akush Ginekol (Sofiia) , vol.45 , pp. 16-28
    • Orbetsova, M.1    Kamenov, Z.2    Kolarov, G.3    Zakharieva, S.4    Khristov, V.5    Atanasova, I.6
  • 43
    • 84866489792 scopus 로고    scopus 로고
    • Effects of thiazolidinediones on polycystic ovary syndrome: A meta-analysis of randomized placebo-controlled trials
    • Du Q, Yang S, Wang YJ, Wu B, Zhao YY, Fan B. Effects of thiazolidinediones on polycystic ovary syndrome: a meta-analysis of randomized placebo-controlled trials. Adv Ther 2012; 29: 763-74.
    • (2012) Adv Ther , vol.29 , pp. 763-774
    • Du, Q.1    Yang, S.2    Wang, Y.J.3    Wu, B.4    Zhao, Y.Y.5    Fan, B.6
  • 44
    • 80055057319 scopus 로고    scopus 로고
    • Alteration of cardiovascular risk parameters in women with polycystic ovary syndrome who were prescribed to ethinylestradiolcyproterone acetate
    • Gode F, Karagoz C, Posaci C, Saatli B, Uysal D, Secil M, et al. Alteration of cardiovascular risk parameters in women with polycystic ovary syndrome who were prescribed to ethinylestradiolcyproterone acetate. Arch Gynecol Obstet 2011; 284: 923-9.
    • (2011) Arch Gynecol Obstet , vol.284 , pp. 923-929
    • Gode, F.1    Karagoz, C.2    Posaci, C.3    Saatli, B.4    Uysal, D.5    Secil, M.6
  • 45
    • 73049094839 scopus 로고    scopus 로고
    • Endothelial function and insulin resistance in polycystic ovary syndrome: The effects of medical therapy
    • Teede HJ, Meyer C, Hutchison SK, Zoungas S, McGrath BP, Moran LJ. Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy. Fertil Steril 2010; 93: 184-91.
    • (2010) Fertil Steril , vol.93 , pp. 184-191
    • Teede, H.J.1    Meyer, C.2    Hutchison, S.K.3    Zoungas, S.4    McGrath, B.P.5    Moran, L.J.6
  • 46
    • 75749115194 scopus 로고    scopus 로고
    • Effect of metformin on serum visfatin levels in patients with polycystic ovary syndrome
    • Ozkaya M, Cakal E, Ustun Y, Engin-Ustun Y. Effect of metformin on serum visfatin levels in patients with polycystic ovary syndrome. Fertil Steril 2010; 93: 880-4.
    • (2010) Fertil Steril , vol.93 , pp. 880-884
    • Ozkaya, M.1    Cakal, E.2    Ustun, Y.3    Engin-Ustun, Y.4
  • 47
    • 77955713461 scopus 로고    scopus 로고
    • Effect of oral contraceptive containing ethinyl estradiol combined with drospirenone vs. desogestrel on clinical and biochemical parameters in patients with polycystic ovary syndrome
    • Kriplani A, Periyasamy AJ, Agarwal N, Kulshrestha V, Kumar A, Ammini AC. Effect of oral contraceptive containing ethinyl estradiol combined with drospirenone vs. desogestrel on clinical and biochemical parameters in patients with polycystic ovary syndrome. Contraception 2010; 82: 139-46.
    • (2010) Contraception , vol.82 , pp. 139-146
    • Kriplani, A.1    Periyasamy, A.J.2    Agarwal, N.3    Kulshrestha, V.4    Kumar, A.5    Ammini, A.C.6
  • 48
    • 33947506395 scopus 로고    scopus 로고
    • Efficacy of an oral contraceptive containing drospirenone in the treatment of women with polycystic ovary syndrome
    • Pehlivanov B, Mitkov M. Efficacy of an oral contraceptive containing drospirenone in the treatment of women with polycystic ovary syndrome. Eur J Contracept Reprod Health Care 2007; 12: 30-5.
    • (2007) Eur J Contracept Reprod Health Care , vol.12 , pp. 30-35
    • Pehlivanov, B.1    Mitkov, M.2
  • 49
    • 84873410291 scopus 로고    scopus 로고
    • Body composition in lean women with polycystic ovary syndrome: Effect of ethinyl estradiol and drospirenone combination
    • Aydin K, Cinar N, Aksoy DY, Bozdag G, Yildiz BO. Body composition in lean women with polycystic ovary syndrome: effect of ethinyl estradiol and drospirenone combination. Contraception 2013; 87: 358-62.
    • (2013) Contraception , vol.87 , pp. 358-362
    • Aydin, K.1    Cinar, N.2    Aksoy, D.Y.3    Bozdag, G.4    Yildiz, B.O.5
  • 50
    • 70449134782 scopus 로고    scopus 로고
    • Short term effects of spironolactone on blood lipid profile: A 3-month study on a cohort of young women with hirsutism
    • Nakhjavani M, Hamidi S, Esteghamati A, Abbasi M, Nosratian-Jahromi S, Pasalar P. Short term effects of spironolactone on blood lipid profile: a 3-month study on a cohort of young women with hirsutism. Br J Clin Pharmacol 2009; 68: 634-7.
    • (2009) Br J Clin Pharmacol , vol.68 , pp. 634-637
    • Nakhjavani, M.1    Hamidi, S.2    Esteghamati, A.3    Abbasi, M.4    Nosratian-Jahromi, S.5    Pasalar, P.6
  • 51
    • 2942677215 scopus 로고    scopus 로고
    • Comparison of efficacy of spironolactone with metformin in the management of polycystic ovary syndrome: An open-labeled study
    • Ganie MA, Khurana ML, Eunice M, Gupta N, Gulati M, Dwivedi SN, et al. Comparison of efficacy of spironolactone with metformin in the management of polycystic ovary syndrome: an open-labeled study. J Clin Endocrinol Metab 2004; 89: 2756-62.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2756-2762
    • Ganie, M.A.1    Khurana, M.L.2    Eunice, M.3    Gupta, N.4    Gulati, M.5    Dwivedi, S.N.6


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