Effect of Chinese herbal medicine for nourishing yin, supplementing qi, and activating blood on the Th1/Th2 immune balance in peripheral blood in patients with primary Sjogren's syndrome

Chinese Journal of Integrative Medicine

Volumn 19, Issue 9, 2013, Pages 696-700

  Wu, Guo Lin ^a   Li, Tian Yi ^b   Fan, Yong Sheng ^b   Yu, Guo You ^a   Chen, Jiu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

and activating blood; Chinese herbal medicine; disease activity; interferon ; interleukin 4; nourishing yin; primary Sjogren's syndrome; supplementing qi

Indexed keywords

ARTEMISIA APIACEA EXTRACT; CASSIAE EXTRACT; CHINESE DRUG; CLEMATIDIS EXTRACT; CORYDALIS EXTRACT; GAMMA INTERFERON; GENTIANA MACROPHYLLA EXTRACT; HYDROXYCHLOROQUINE SULFATE; IMMUNOGLOBULIN G; INTERLEUKIN 4; LIGUSTRUM LUCIDUM EXTRACT; LYCOPODTI EXTRACT; MORI EXTRACT; PAEONIA RADIX; PLANT EXTRACT; POLYGONATUM EXTRACT; PSEUDOSTELLARIAE EXTRACT; PUERARIA EXTRACT; RHODIOLA EXTRACT; SARCANDRA EXTRACT; SARCANDRA GLABRA EXTRACT; SARCODACTYLIS EXTRACT; SCHISANDRA CHINENSIS EXTRACT; SIEGESBECKIAE EXTRACT; SMOKED PLUM EXTRACT; TRICHOSANTHIS EXTRACT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DISEASE ACTIVITY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; SJOEGREN SYNDROME; TH1 TH2 BALANCE;

ADULT; AGED; BLOOD SEDIMENTATION; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-4; MALE; MIDDLE AGED; QI; SJOGREN'S SYNDROME; TH1-TH2 BALANCE; YIN-YANG; YOUNG ADULT;

EID: 84883303596     PISSN: 16720415     EISSN: 19930402     Source Type: Journal    
DOI: 10.1007/s11655-013-1565-9     Document Type: Article

References (14)

1. Zhao Y, Dong Y. The clinical picture of primary Sjogren's syndrome. Beijing Med (Chin) 1997;9:100-104.
2. Zhou Q, Bai T, Wu HY. Expression of Th1/Th2 and Fas/FasL in the labial salivary gland of patients with Sjogren's syndrome and its significance. Acta Acad Med Xuzhou (Chin) 2008;28:28-30.
3. Wu GL, Han YM, Fan YS, Yu GY. Effects of Chinese herbal medicine for Yiqi Yangyin Quyu in treating Sjogren's syndrome and on patients immunologic function. Chin J Integr Tradit West Med (Chin) 2006;26:322-324.
4. Wu GL, Li TY, Fan RS, YU GY. Therapeutic effect of Chinese herbal medicine for Yiqi Yangyin Quyu on the level of osteopontin in peripheral blood and quality of life in patients with primary Sjogren's syndrome. Chin J Integr Med 2011;17:109-113.
5. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, et al. Classtication criteria for Sjogren's syndrome: a rerised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002;61:554-558.
6. Ruddy S, Harris ED Jr, Sledge CB, eds. Kelley's textbook of rheumatology. Philadelphia: WB Saunders Company; 2001:1028.
7. Mitsias DI, Tzioufas AG, Veiopoulou C, Zintzaras E, Tassios IK, Kogopoulou O, et al. The Th1, Th2 cytokine balance changes with the progress of the immunopathological lesion of Sjogren's syndrome. Clin Exp Immunol 2002;128:562-568.
8. Lit LC, Wong CK, Li EK, Tam LS, Lam CW, Lo YM. Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus. J Rheumatol 2007;34:89-96.
9. Wada H, Seki S, Takahashi T. Combined spinal and general anesthesia attenuates liver metastasis by preserving Th1/Th2 cytokine balance. Anesthesiology 2007;106:499-506.
10. Zhuang JH, Lin HP, Xu SM, Li B, Zhang LJ, Li JS, et al. Expression of interferon-γ and interlukin-4 in the labial saliary gland of patients with Sjogren's syndrome and its relationship with infiltration of lymphocytes. J Gannan Med Coll (Chin) 2007;27:165-167.
11. Dawson LJ, Caulfield VL, Stanbury JB, Field AE, Christmas SE, Smith PM. Hydroxy chloroquine therapy in patients with primary Sjogren's syndrome may improve salivary gland hypofunetion by inhibition of glandular cholinesterase. Rheumatology (Oxford) 2005;44:449-455.
12. Wu GL, Pu XH, Li TY, Yu GY. Study on treatment for nourishing yin, strengthening qi, and activating blood on submaxillary glands of NOD mice with Sjogren's syndrome. Gansu J Tradit Chin Med (Chin) 2012;25:29-34.
13. Li X, Qiu YJ, Han JP. Study on the change of T cell subsets in patients with primary Sjogren's syndrome. J Tianjin Med Univ (Chin) 2008;14:51-54.
14. Zhao Y, Fei YY, Deng XX, Zhang PL, Gan XD, Shi YP, et al. Significance of anti-α-fodrin antibody in the diagnosis of Sjogren's syndrome and its correlation with clinical manifestations. Chin J Rheumatol (Chin) 2005;9:261-264.