Stimulation of aldosterone synthesis by angiotensin II in the brain: Support for positive feedback in hypertension?

Hypertension

Volumn 62, Issue 3, 2013, Pages 459-460

  Scheuer, Deborah A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN II; CORTICOSTERONE;

ALDOSTERONE BLOOD LEVEL; CEREBROSPINAL FLUID; HORMONE SYNTHESIS; HYPERTENSION; NONHUMAN; NOTE; POSITIVE FEEDBACK; PRIORITY JOURNAL;

ALDOSTERONE; ANIMALS; BRAIN; CORTICOSTERONE; HYPERTENSION; MALE;

EID: 84883296890     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01649     Document Type: Note

References (11)

1. Gomez-Sanchez EP, Ahmad N, Romero DG, Gomez-Sanchez CE. Is aldosterone synthesized within the rat brain? Am J Physiol Endocrinol Metab. 2005;288:E342-E346.
2. Gomez-Sanchez EP, Samuel J, Vergara G, Ahmad N. Effect of 3betahydroxysteroid dehydrogenase inhibition by trilostane on blood pressure in the Dahl salt-sensitive rat. Am J Physiol Regul Integr Comp Physiol. 2005;288:R389-R393.
3. Huang BS, White RA, Jeng AY, Leenen FH. Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol. 2009;296:R994-R1000.
4. Gomez-Sanchez EP, Gomez-Sanchez CM, Plonczynski M, Gomez-Sanchez CE. Aldosterone synthesis in the brain contributes to Dahl saltsensitive rat hypertension. Exp Physiol. 2010;95:120-130.
5. Rigel DF, Fu F, Beil M, Hu C-W, Liang G, Jeng AY. Pharmacodynamic and pharmacokinetic characteriation of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: Comparison with the 11ß-hydroxylase inhibitor metyrapone. JPET. 2010;334:232-243.
6. Huang BS, White RA, Ahmad M, Leenen FHH. Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. Hypertension. 2013;62:564-571.
7. Xue B, Zhang Z, Roncari CF, Guo F, Johnson AK. Aldosterone acting through the central nervous system sensitizes angiotensin II-induced hypertension. Hypertension. 2012;60:1023-1030.
8. Xue B, Beltz TG, Yu Y, Guo F, Gomez-Sanchez CE, Hay M, Johnson AK. Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. Am J Physiol Heart Circ Physiol. 2011;300:H555-H564.
9. Huang BS, Ahmadi S, Ahmad M, White RA, Leenen FH Central neuronal activation and pressor responses induced by circulating ANG II: Role of the brain aldosterone-"ouabain" pathway. Am J Physiol Heart Circ Physiol. 2010;299:H422-H430.
10. Gomez-Sanchez EP. Mineralocorticoid receptors in the brain and cardiovascular regulation: Minority rulé Trends Endocrinol Metab. 2011;22:179-187.
11. Gómez-Sánchez EP, Venkataraman MT, Thwaites D, Fort C. ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension. Am J Physiol. 1990;258(4 Pt 1):E649-E653.