Protonation of trimethylamine N-oxide (TMAO) is required for stabilization of RNA tertiary structure

Biophysical Chemistry

Volumn 184, Issue , 2013, Pages 8-16

  Denning, Elizabeth J ^a   Thirumalai, D ^b   Mackerell, Alexander D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b Bldg 142   (United States)

Author keywords

Constant pH simulations; Molecular dynamics simulations; RNA folding; RNA tertiary structure

Indexed keywords

HYDROGEN; PHOSPHATE; QUEUOSINE; RNA; TRIMETHYLAMINE OXIDE;

ARTICLE; COMPARATIVE STUDY; CRYSTAL STRUCTURE; DEHYDRATION; INTERACTIONS WITH RNA; LIGAND BINDING; MOLECULAR DYNAMICS; POPULATION; PREQ 1 RIBOSWITCH; PRIORITY JOURNAL; PROTON TRANSPORT; RIBOSWITCH; RNA STABILITY; RNA STRUCTURE; RNA TERTIARY STRUCTURE; STATIC ELECTRICITY;

CONSTANT PH SIMULATIONS; MOLECULAR DYNAMICS SIMULATIONS; PK(A); PREQ(1) RIBOSWITCH; RNA FOLDING; RNA TERTIARY STRUCTURE;

HYDROGEN-ION CONCENTRATION; METHYLAMINES; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTONS; RNA;

EID: 84883281341     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2013.08.002     Document Type: Article

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