Neuroendocrine markers and psychological features in patients with irritable bowel syndrome

International Journal of Colorectal Disease

Volumn 28, Issue 9, 2013, Pages 1203-1208

  Stasi, Cristina ^a,d   Bellini, Massimo ^b   Costa, Francesco ^b   Mumolo, Maria Gloria ^b   Ricchiuti, Angelo ^b   Grosso, Mariano ^b   Duranti, Emiliano ^b   Metelli, Maria Rosaria ^b   Gambaccini, Dario ^b   Bianchi, Lea ^b   Di Tanna, Gian Luca ^c   Laffi, Giacomo ^a   Taddei, Stefano ^b   Marchi, Santino ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Dipartimento di Medicina Interna   (Italy)

Author keywords

Irritable bowel syndrome; Neuroendocrine markers; Psychological features

Indexed keywords

HYDROCORTISONE; NEUROPEPTIDE Y; SEROTONIN;

ADULT; AGED; ANXIETY; ARTICLE; CLINICAL FEATURE; COMPARATIVE STUDY; CONSTIPATION; CONTROLLED STUDY; DIARRHEA; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE SEVERITY; FEAR; FEMALE; HUMAN; HYDROCORTISONE URINE LEVEL; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; NEUROENDOCRINE MARKER; OBSESSIVE COMPULSIVE DISORDER; PATHOGENESIS; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; QUESTIONNAIRE; SEROTONIN BLOOD LEVEL; SOCIAL ASPECT; SOCIAL INGENUITY; STATE ANXIETY; TRAIT ANXIETY;

ADULT; AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; HUMANS; HYDROCORTISONE; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; NEUROPEPTIDE Y; NEUROSECRETORY SYSTEMS; SEROTONIN; YOUNG ADULT;

EID: 84883274846     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-013-1646-4     Document Type: Article

References (39)

1. Camilleri M, Choi MG (1997) Irritable bowel syndrome. Aliment Pharmacol Ther 11:3-15
2. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC (2006) Functional bowel disorders. Gastroenterology 130:1480-1491
3. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Müller-Lissner SA (1999) Functional bowel disorders and functional abdominal pain. Gut 45:II43-II47
4. Lydiard RB, Fossey MD, Marsh W, Ballenger JC (1993) Prevalence of psychiatric disorders in patients with irritable bowel syndrome. Psychosomatics 34:229-234
5. Drossman DA, Creed FH, Olden KW, Svedlund J, Toner BB, Whitehead WE (1999) Psychosocial aspects of the functional gastrointestinal disorders. Gut 45:II 25-II 30
6. Gunn MC, Cavin AA, Mansfield JC (2003) Management of irritable bowel syndrome. Postgrad Med J 79:154-158
7. Kim DY, Camilleri M (2000) Serotonin: a mediator of the brain-gut connection. Am J Gastroenterol 95:2698-2709
8. Stasi C, Rosselli M, Bellini M, Laffi G, Milani S (2012) Altered neuro-endocrine-immune pathways in the irritable bowel syndrome: the top-down and the bottom-up model. J Gastroenterol. doi: 10.1007/s00535-012-0627-7
9. Karantanos T, Markoutsaki T, Gazouli M, Anagnou NP, Karamanolis DG (2010) Current insights in to the pathophysiology of irritable bowel syndrome. Gut Pathog 2:3
10. Kawahito Y, Sano H, Mukai S, Asai K, Kimura S, Yamamura Y, Kato H, Chrousos GP, Wilder RL, Kondo M (1995) Corticotropin releasing hormone in colonic mucosa in patients with ulcerative colitis. Gut 37:544-551
11. Stasi C, Frisoli A, Bellini M, Taddei S, Costa F, Biagi S, Mumolo MG, Ricchiuti A, Marchi S (2006) Increased levels of neuropeptide Y in patients with irritable bowel syndrome. Dig Liver Dis 38:S131
12. Bearcroft CP, Perret D, Farthing MJG (1998) Postprandial plasma 5-hydroxytryptamine in diarrhoea-predominant irritable bowel syndrome: a pilot study. Gut 42:42-46
13. Bellini M, Rappelli L, Blandizzi C, Costa F, Stasi C, Colucci R, Giannaccini G, Marazziti D, Betti L, Baroni S, Mumolo MG, Marchi S, Del Tacca M (2003) Platelet serotonin transporter in patients with diarrhea-predominant irritable bowel syndrome both before and after treatment with alosetron. Am J Gastroenterol 98:2705-2711
14. Engsbro AL, Simren M, Bytzer P (2012) The Rome II and Rome III criteria identify the same subtype-populations in irritable bowel syndrome: agreement depends on the method used for symptom report. Neurogastroenterol Motil. doi: 10.1111/j.1365-2982.2012.01908
15. Francis CY, Morris J, Whorwell PJ (1997) The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther 11:395-402
16. Hodgson RJ, Rachman S (1977) Obsessional-compulsive complaints. Behav Res Ther 15:389-395
17. Spielberger CD (1983) State-trait anxiety inventory: a comprehensive bibliography. Consulting Psychologist, Palo Alto
18. Bertolotti G, Michielin P, Sanavio E, Simonetti G, Vidotto G, Zorn AM (1985) CBA - Cognitive behavioral assessment 2.0. - Una batteria a vasto spettro per la pratica clinico-terapeutica - Firenze, Organizzazioni Speciali
19. Drossman DA, McKee DC, Sandler RS, Mitchell CM, Cramer EM, Lowman BC, Burger AL (1988) Psychosocial factors in the irritable bowel syndrome. A multivariate study of patients and nonpatients with irritable bowel syndrome. Gastroenterology 95:701-708
20. Heitkemper M, Jarret M, Cain K, Shaver J, Bond E, Woods NF, Walker E (1996) Increased urine catecholamines and cortisol in women with irritable bowel syndrome. Am J Gastroenterol 91:906-913
21. Plotsky PM, Owens MJ, Nemeroff CB (1998) Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis. Psychiatr Clin North Am 21:293-307
22. Böhmelt AH, Nater UM, Franke S, Hellhammer DH, Ehlert U (2005) Basal and stimulated hypothalamic-pituitary-adrenal axis activity in patients with functional gastrointestinal disorders and healthy controls. Psychosom Med 67:288-294
23. Chang L, Sundaresh S, Elliott J, Anton PA, Baldi P, Licudine A, Mayer M, Vuong T, Hirano M, Naliboff BD, Ameen VZ, Mayer EA (2009) Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in irritable bowel syndrome. Neurogastroenterol Motil 21:149-159
24. Elsenbruch S, Orr WC (2001) Diarrhea- and constipation-predominant IBS patients differ in postprandial autonomic and cortisol responses. Am J Gastroenterol 96:460-466
25. Fukudo S, Nomura T, Hongo M (1998) Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome. Gut 42:845-849
26. Dinan TG, Quigley EM, Ahmed SM, Scully P, O'Brien S, O'Mahony L, O'Mahony S, Shanahan F, Keeling PW (2006) Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? Gastroenterology 130:304-311
27. Kaplan HI, Sadock BJ, Grebb JA (1994) Kaplan and Sadock's synopsis of psychiatry: behavioral sciences clinical psychiatry, 7th edn. Williams & Wilkins, Baltimore
28. Iovino P, Azpiroz F, Domingo E, Malagelada JR (1995) The sympathetic nervous system modulates perception and reflex responses to gut distention in humans. Gastroenterology 108:680-686
29. Waring WS, Chui M, Japp A, Nicol EF, Ford MJ (2004) Autonomic cardiovascular responses are impaired in women with irritable bowel syndrome. J Clin Gastroenterol 38:658-663
30. Heitkemper M, Jarret M, Bond E, Walzer E, Rockwell M (1994) Increased sympathetic nervous system activity in women with IBS. Gastroenterology 106:A509
31. Jorgensen LS, Christiansen P, Raundahl U, Ostgaard S, Christensen NJ, Fenger M, Flachs H (1993) Autonomic nervous system function in patients with functional abdominal pain. An experimental study. Scand J Gastroenterol 28:63-68
32. Levi L (1972) Stress and distress in response to psychosocial stimuli. Laboratory and real life studies on sympathoadrenomedullary and related reactions. Acta Med Scand 528:1-166
33. Silverman DH, Munakata JA, Ennes H, Mandelkern MA, Hoh CK, Mayer EA (1997) Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 112:64-72
34. Drossman DA, Ringel Y, Vogt BA, Leserman J, Lin W, Smith JK, Whitehead W (2003) Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome. Gastroenterology 124:754-761
35. Prior A, Colgan SM, Whorwell PJ (1990) Changes in rectal sensitivity after hypnotherapy with irritable bowel syndrome. Gut 31:896-898
36. Simrén M, Abrahamsson H, Bjornsson ES (2001) An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome. Gut 48:20-27
37. Park JH, Rhee PL, Kim HS, Lee JH, Kim YH, Kim JJ, Rhee JC (2006) Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome. J Gastroenterol Hepatol 21(1 Pt 1):71-78
38. Barbara G, Stanghellini V, De Giorgio R, Cremon C, Cottrell GS, Santini D, Pasquinelli G, Morselli-Labate AM, Grady EF, Bunnett NW, Collins SM, Corinaldesi R (2004) Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 126:693-702
39. Rodríguez-Fandiño O, Hernández-Ruiz J, Schmulson M (2010) From cytokines to toll-like receptors and beyond - current knowledge and future research needs in irritable bowel syndrome. J Neurogastroenterol Motil 16:363-373