Nonpeptidic angiotensin II AT1 receptor antagonists derived from 6-substituted aminocarbonyl and acylamino benzimidazoles

European Journal of Medicinal Chemistry

Volumn 69, Issue , 2013, Pages 44-54

  Zhang, Jun ^a   Wang, Jin Liang ^a   Yu, Wei Fa ^a   Zhou, Zhi Ming ^a   Tao, Wen Chang ^a   Wang, Yi Cheng ^a   Xue, Wei Zhe ^a   Xu, Di ^a   Hao, Li Ping ^a   Han, Xiao Feng ^a   Fei, Fan ^a   Liu, Ting ^b   Liang, Ai Hua ^b  

^a BEIJING INSTITUTE OF TECHNOLOGY   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Acylamino benzimidazole; Aminoacyl benzimidazole; Angiotensin II AT1 receptor antagonists; Hypertension

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; BENZIMIDAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; AORTA STRIP; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; IC 50; MALE; NONHUMAN; RAT; RECEPTOR BINDING;

ACYLAMINO BENZIMIDAZOLE; AMINOACYL BENZIMIDAZOLE; ANGIOTENSIN II AT1 RECEPTOR ANTAGONISTS; HYPERTENSION;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; BENZIMIDAZOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTOR, ANGIOTENSIN, TYPE 1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84883252740     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.08.014     Document Type: Article

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