The biochemistry of the metabolic poison propionate 3-nitronate and its conjugate acid, 3-nitropropionate

IUBMB Life

Volumn 65, Issue 9, 2013, Pages 759-768

  Francis, Kevin ^a   Smitherman, Crystal ^a   Nishino, Shirley F ^b   Spain, Jim C ^b   Gadda, Giovanni ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b Georgia Institute of Technology   (United States)

Author keywords

3 nitropropionic acid; detoxification; flavoprotein; mitochondria; nitronate monooxygenase; oxidation; propionate 3 nitronate

Indexed keywords

3 NITROPROPIONIC ACID; ALDEHYDE DEHYDROGENASE; CYTOCHROME C; PROPIONATE 3 NITRONATE; PROPIONIC ACID DERIVATIVE; RIBONUCLEASE T1; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

AMINO ACID SEQUENCE; ASPERGILLUS FLAVUS; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; CITRIC ACID CYCLE; COVALENT BOND; CRYSTAL STRUCTURE; ENERGY YIELD; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; HUMAN; INDIGOFERA; LD 50; LIVER MITOCHONDRION; LIVESTOCK; LOW TEMPERATURE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROSPORA CRASSA; NEUROTOXICITY; NITRIFICATION; NITROGEN FIXATION; NONHUMAN; OLIGOMERIZATION; OPEN READING FRAME; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PENICILLIUM; PENICILLIUM ATROVENETUM; PH; PHYSICAL CHEMISTRY; PKA; PROTEIN DEGRADATION; PROTON TRANSPORT; PSEUDOMONAS AERUGINOSA; RESPIRATORY CHAIN; REVIEW; STEADY STATE; STOICHIOMETRY; TALUS;

ANIMALIA; BACTERIA (MICROORGANISMS); FABACEAE; FUNGI;

3-NITROPROPIONIC ACID; DETOXIFICATION; FLAVOPROTEIN; MITOCHONDRIA; NITRONATE MONOOXYGENASE; OXIDATION; PROPIONATE 3-NITRONATE;

ANIMALS; FUNGAL PROTEINS; HUMANS; MIXED FUNCTION OXYGENASES; MYCOTOXINS; NITRO COMPOUNDS; OXIDATION-REDUCTION; PLANT PROTEINS; PROPIONATES; SUCCINATE DEHYDROGENASE;

EID: 84883240261     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1195     Document Type: Review

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