Efficacy of an artificial tear emulsion in patients with dry eye associated with meibomian gland dysfunction

Clinical Ophthalmology

Volumn 7, Issue , 2013, Pages 1713-1722

  Sindt, Christine W ^a   Foulks, Gary N ^b  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Corneal staining; Impact on dry eye in everyday life; MGD; Ophthalmic solutions; Tear film breakup time; Work Productivity and activity impairment

Indexed keywords

CYCLOSPORIN; SYSTANE; UNCLASSIFIED DRUG;

ADULT; AGED; ANXIETY; ARTICLE; BLURRED VISION; BURNING SENSATION; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; DRY EYE; DRY EYE IN EVERYDAY LIFE QUESTIONNAIRE; EMPLOYMENT; EMULSION; EYE REDNESS; FEMALE; HUMAN; MALE; MEIBOMIAN GLAND DYSFUNCTION; PATIENT PREFERENCE; PATIENT SATISFACTION; QUALITY OF LIFE; QUESTIONNAIRE; SIDE EFFECT; STAINING; TEAR FILM; VISUAL ACUITY; WORK PRODUCTIVITY AND ACTIVITY IMPAIRMENT QUESTIONNAIRE;

EID: 84883189833     PISSN: 11775467     EISSN: 11775483     Source Type: Journal    
DOI: 10.2147/OPTH.S35833     Document Type: Article

References (30)

1. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5(2):75-92.
2. Nelson JD, Shimazaki J, Benitez-del-Castillo JM, etal. The International Workshop on Meibomian Gland Dysfunction: Report of the Definition and Classification Subcommittee. Invest Ophthalmol Vis Sci. 2011;52(4):1930-1937.
3. Albietz JM. Prevalence of dry eye subtypes in clinical optometry practice. Optom Vis Sci. 2000;77(7):357-363.
4. Lekhanont K, Rojanaporn D, Chuck RS, Vongthongsri A. Prevalence of dry eye in Bangkok, Thailand. Cornea. 2006;25(10):1162-1167.
5. Lin PY, Tsai SY, Cheng CY, Liu JH, Chou P, Hsu WM. Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study. Ophthalmology. 2003;110(6):1096-1101.
6. Nichols KK. The international workshop on meibomian gland dysfunction: introduction. Invest Ophthalmol Vis Sci. 2011;52(4): 1917-1921.
7. Nichols KK, Foulks GN, Bron AJ, etal. The international workshop on meibomian gland dysfunction: executive summary. Invest Ophthalmol Vis Sci. 2011;52(4):1922-1929.
8. Nichols KK, Nichols JJ, Mitchell GL. The lack of association between signs and symptoms in patients with dry eye disease. Cornea. 2004;23(8):762-770.
9. Isreb MA, Greiner JV, Korb DR, etal. Correlation of lipid layer thickness measurements with fluorescein tear film break-up time and Schirmer's test. Eye. 2003;17(1):79-83.
10. Geerling G, Tauber J, Baudouin C, etal. The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction. Invest Ophthalmol Vis Sci. 2011;52(4):2050-2064.
11. Benelli U. Systane lubricant eye drops in the management of ocular dryness. Clin Ophthalmol. 2011;5:783-790.
12. Alcon Research. Evaluation of FID 114657in dry eye subjects. In: ClinicalTrials. gov [website on the Internet]. Bethseda, MD: US National Library of Medicine; 2010 [updated January 31, 2012]. Available from: http://www.clinicaltrials.gov/ct2/show/NCT01079858. NLM identifier: NCT01079858. Accessed March 28, 2013.
13. Mathers WD, Shields WJ, Sachdev MS, Petroll WM, Jester JV. Meibomian gland dysfunction in chronic blepharitis. Cornea. 1991;10(4):277-285.
14. Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J. 1995;21(4):221-232.
15. Rajagopalan K, Abetz L, Mertzanis P, etal. Comparing the discriminative validity of two generic and one disease-specific health-related quality of life measures in a sample of patients with dry eye. Value Health. 2003;8(2):168-174.
16. Fairchild CJ, Chalmers RL, Begley CG. Clinically important difference in dry eye: change in IDEEL-symptom bother. Optom Vis Sci. 2008;85(8):699-707.
17. Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993;4(5):353-365.
18. Reilly MC, Gerlier L, Brabant Y, Brown M. Validity, reliability, and responsiveness of the work productivity and activity impairment questionnaire in Crohn's disease. Clin Ther. 2008;30(2):393-404.
19. Yu J, Asche CV, Fairchild CJ. The economic burden of dry eye disease in the United States: a decision tree analysis. Cornea. 2011;30(4): 379-387.
20. Shi L, Liu J, Koleva Y, Fonseca V, Kalsekar A, Pawaskar M. Concordance of adherence measurement using self-reported adherence questionnaires and medication monitoring devices. Pharmacoeconomics. 2010;28(12):1097-1107.
21. Robin AL, Novack GD, Covert DW, Crockett RS, Marcic TS. Adherence in glaucoma: objective measurements of once-daily and adjunctive medication use. Am J Ophthalmol. 2007;144(4):533-540.
22. Siatkowski RM, Cotter S, Miller JM, etal; US Pirenzepine Study Group. Safety and efficacy of 2% pirenzepine ophthalmic gel in children with myopia: a 1-year, multicenter, double-masked, placebo-controlled parallel study. Arch Ophthalmol. 2004;122(11):1667-1674.
23. Cohen J. Statistical Power Analysis for the Behavioral Sciences, 2nd ed. Hillsdale, NJ: Lawrence Erlbaum; 1988.
24. Norn M. Meibomian orifices and Marx's line. Studied by triple vital staining. Acta Ophthalmol (Copenh). 1985;63(6):698-700.
25. Korb DR, Blackie C, Meadows D, Christensen M, Tudor M. Evaluation of extended tear stability by two emulsion-based artificial tears. Poster presented at the 6th International Conference on the Tear Film and Ocular Surface: Basic Science and Clinical Relevance, September 22-25, 2010, Florence, Italy.
26. Arita R, Itoh K, Inoue K, Amano S. Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population. Ophthalmology. 2008;115(5):911-915.
27. Arita R, Itoh K, Maeda S, etal. Proposed diagnostic criteria for obstructive meibomian gland dysfunction. Ophthalmology. 2009;116(11): 2058-2063.
28. Arita R, Itoh K, Maeda S, Maeda K, Amano S. A newly developed noninvasive and mobile pen-shaped meibography system. Cornea. 2013;32(3):242-247.
29. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26(4):347-353.
30. Perry HD, Doshi-Carnevale S, Donnenfeld ED, Solomon R, Biser SA, Bloom AH. Efficacy of commercially available topical cyclosporine A 0.05% in the treatment of meibomian gland dysfunction. Cornea. 2006;25(2):171-175.