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Volumn 154, Issue 9, 2013, Pages 3437-3446

Expression and putative function of kisspeptins and their receptors during early development in medaka

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; KISSPEPTIN; KISSPEPTIN 1; KISSPEPTIN 2; RNA; UNCLASSIFIED DRUG;

EID: 84883176500     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1065     Document Type: Article
Times cited : (27)

References (52)
  • 1
    • 42449107801 scopus 로고    scopus 로고
    • Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (Oryza latipes)
    • Kanda S, Akazome Y, Matsunaga T, et al. Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (Oryza latipes). Endocrinology 2008; 149:2467-2476.
    • (2008) Endocrinology , vol.149 , pp. 2467-2476
    • Kanda, S.1    Akazome, Y.2    Matsunaga, T.3
  • 2
    • 70249145863 scopus 로고    scopus 로고
    • Evidence for two distinct KiSS genes in non-placental vertebrates that encode kisspeptins with different gonadotropin-releasing activities in fish and mammals
    • Felip A, Zanuy S, Pineda R, Pinilla L, Carrillo M, Tena-Sempere M, Gómez A. Evidence for two distinct KiSS genes in non-placental vertebrates that encode kisspeptins with different gonadotropin-releasing activities in fish and mammals. Mol Cell Endocrinol 2009; 312:61-71.
    • (2009) Mol Cell Endocrinol , vol.312 , pp. 61-71
    • Felip, A.1    Zanuy, S.2    Pineda, R.3    Pinilla, L.4    Carrillo, M.5    Tena-Sempere, M.6    Gómez, A.7
  • 4
    • 0032533648 scopus 로고    scopus 로고
    • Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1)
    • West A, Vojta PJ, Welch DR, Weissman BE. Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1). Genomics 1998;54:145-148.
    • (1998) Genomics , vol.54 , pp. 145-148
    • West, A.1    Vojta, P.J.2    Welch, D.R.3    Weissman, B.E.4
  • 5
    • 0034817121 scopus 로고    scopus 로고
    • FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54
    • Clements MK, McDonald TP, Wang R, et al. FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. Biochem Biophys Res Commun 2001;284:1189-1193.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 1189-1193
    • Clements, M.K.1    McDonald, T.P.2    Wang, R.3
  • 6
    • 0035860778 scopus 로고    scopus 로고
    • The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54
    • Kotani M, Detheux M, Vandenbogaerde A, et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 2001; 276:34631-34636.
    • (2001) J Biol Chem , vol.276 , pp. 34631-34636
    • Kotani, M.1    Detheux, M.2    Vandenbogaerde, A.3
  • 7
    • 0035800824 scopus 로고    scopus 로고
    • AXOR12, a novel humanGprotein-coupled receptor, activated by the peptide KiSS-1
    • Muir AI, Chamberlain L, Elshourbagy NA, et al. AXOR12, a novel humanGprotein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem 2001;276:28969-28975.
    • (2001) J Biol Chem , vol.276 , pp. 28969-28975
    • Muir, A.I.1    Chamberlain, L.2    Elshourbagy, N.A.3
  • 8
    • 0035978639 scopus 로고    scopus 로고
    • Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor
    • Ohtaki T, Shintani Y, Honda S, et al. Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 2001;411:613-617.
    • (2001) Nature , vol.411 , pp. 613-617
    • Ohtaki, T.1    Shintani, Y.2    Honda, S.3
  • 9
    • 0030956852 scopus 로고    scopus 로고
    • Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1
    • Lee JH, Welch DR. Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer Res 1997;57:2384-2387.
    • (1997) Cancer Res , vol.57 , pp. 2384-2387
    • Lee, J.H.1    Welch, D.R.2
  • 10
  • 12
    • 0344064059 scopus 로고    scopus 로고
    • The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system
    • Funes S, Hedrick JA, Vassileva G, et al. The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system. Biochem Biophys Res Commun 2003;312:1357-1363.
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 1357-1363
    • Funes, S.1    Hedrick, J.A.2    Vassileva, G.3
  • 14
    • 79955155516 scopus 로고    scopus 로고
    • The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent
    • Prentice LM, d'Anglemont de Tassigny X, McKinney S, et al. The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics 2011;12:209.
    • (2011) BMC Genomics , vol.12 , pp. 209
    • Prentice, L.M.1    D'anglemont De Tassigny, X.2    McKinney, S.3
  • 15
    • 34547910242 scopus 로고    scopus 로고
    • Kisspeptins: A multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system
    • Mead EJ, Maguire JJ, Kuc RE, Davenport AP. Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. Br J Pharmacol 2007;151:1143-1153.
    • (2007) Br J Pharmacol , vol.151 , pp. 1143-1153
    • Mead, E.J.1    Maguire, J.J.2    Kuc, R.E.3    Davenport, A.P.4
  • 16
    • 79951779174 scopus 로고    scopus 로고
    • The vasoactive potential of kisspeptin-10 in the peripheral vasculature
    • Sawyer I, Smillie SJ, Bodkin JV, et al. The vasoactive potential of kisspeptin-10 in the peripheral vasculature. PLoS One 2011;6: e14671.
    • (2011) PLoS One , vol.6
    • Sawyer, I.1    Smillie, S.J.2    Bodkin, J.V.3
  • 17
    • 55649083092 scopus 로고    scopus 로고
    • Factors that regulate KiSS1 gene expression in the hippocampus
    • Arai AC, Orwig N. Factors that regulate KiSS1 gene expression in the hippocampus. Brain Res 2008;1243:10-18.
    • (2008) Brain Res , vol.1243 , pp. 10-18
    • Arai, A.C.1    Orwig, N.2
  • 18
    • 57849151947 scopus 로고    scopus 로고
    • The role of kisspeptin and GPR54 in the hippocampus
    • Arai AC. The role of kisspeptin and GPR54 in the hippocampus. Peptides 2009;30:16-25.
    • (2009) Peptides , vol.30 , pp. 16-25
    • Arai, A.C.1
  • 19
    • 77956785165 scopus 로고    scopus 로고
    • A novel developmental role for kisspeptin in the growth of gonadotrophin-releasing hormone neurites to the median eminence in the mouse
    • Fiorini Z, Jasoni CL. A novel developmental role for kisspeptin in the growth of gonadotrophin-releasing hormone neurites to the median eminence in the mouse. J Neuroendocrinol 2010;22:1113-1125.
    • (2010) J Neuroendocrinol , vol.22 , pp. 1113-1125
    • Fiorini, Z.1    Jasoni, C.L.2
  • 21
    • 84866509842 scopus 로고    scopus 로고
    • Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain
    • Kanda S, Oka Y. Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain. Front Endocrinol (Lausanne) 2012;3:28.
    • (2012) Front Endocrinol (Lausanne) , vol.3 , pp. 28
    • Kanda, S.1    Oka, Y.2
  • 23
    • 53349173553 scopus 로고    scopus 로고
    • Molecular identification and functional characterization of the kisspeptin/kisspeptin receptor system in lower vertebrates
    • Biran J, Ben-Dor S, Levavi-Sivan B. Molecular identification and functional characterization of the kisspeptin/kisspeptin receptor system in lower vertebrates. Biol Reprod 2008;79:776-786.
    • (2008) Biol Reprod , vol.79 , pp. 776-786
    • Biran, J.1    Ben-Dor, S.2    Levavi-Sivan, B.3
  • 24
    • 67849097350 scopus 로고    scopus 로고
    • Structural and functional multiplicity of the kisspeptin/GPR54 system in goldfish (Carassius auratus)
    • Li S, Zhang Y, Liu Y, et al. Structural and functional multiplicity of the kisspeptin/GPR54 system in goldfish (Carassius auratus). J Endocrinol 2009;201:407-418.
    • (2009) J Endocrinol , vol.201 , pp. 407-418
    • Li, S.1    Zhang, Y.2    Liu, Y.3
  • 25
    • 77954182700 scopus 로고    scopus 로고
    • Molecular identification of the Kiss2/Kiss1ra system and its potential function during 17α-methyltestosterone- induced sex reversal in the orange-spotted grouper, Epinephelus coioides
    • Shi Y, Zhang Y, Li S, et al. Molecular identification of the Kiss2/ Kiss1ra system and its potential function during 17α-methyltestosterone- induced sex reversal in the orange-spotted grouper, Epinephelus coioides. Biol Reprod 2010;83:63-74.
    • (2010) Biol Reprod , vol.83 , pp. 63-74
    • Shi, Y.1    Zhang, Y.2    Li, S.3
  • 26
    • 59649119054 scopus 로고    scopus 로고
    • Cloning and expression of kiss2 in the zebrafish and medaka
    • Kitahashi T, Ogawa S, Parhar IS. 2009. Cloning and expression of kiss2 in the zebrafish and medaka. Endocrinology 150:821-831.
    • (2009) Endocrinology , vol.150 , pp. 821-831
    • Kitahashi, T.1    Ogawa, S.2    Parhar, I.S.3
  • 27
    • 84869840352 scopus 로고    scopus 로고
    • Multiple kisspeptin receptors in early osteichthyans provide new insights into the evolution of this receptor family
    • Pasquier J, Lafont AG, Jeng SR, et al. Multiple kisspeptin receptors in early osteichthyans provide new insights into the evolution of this receptor family. PLoS One 2012;7:11.
    • (2012) PLoS One , vol.7 , pp. 11
    • Pasquier, J.1    Lafont, A.G.2    Jeng, S.R.3
  • 28
    • 3042631471 scopus 로고    scopus 로고
    • Stages of normal development in the medaka Oryza latipes
    • Iwamatsu T. Stages of normal development in the medaka Oryza latipes. Mech Dev 2004;121:605-618.
    • (2004) Mech Dev , vol.121 , pp. 605-618
    • Iwamatsu, T.1
  • 29
    • 78149355198 scopus 로고    scopus 로고
    • Single-cell qPCR on dispersed primary pituitary cells-an optimized protocol
    • Hodne K, Haug TM, Weltzien FA. Single-cell qPCR on dispersed primary pituitary cells-an optimized protocol. BMC Mol Biol 2010;11:82.
    • (2010) BMC Mol Biol , vol.11 , pp. 82
    • Hodne, K.1    Haug, T.M.2    Weltzien, F.A.3
  • 30
    • 18144365440 scopus 로고    scopus 로고
    • A quantitative realtime RT-PCR assay for European eel tyrosine hydroxylase
    • Weltzien FA, Pasqualini C, Vernier P, Dufour S. A quantitative realtime RT-PCR assay for European eel tyrosine hydroxylase. Gen Comp Endocrinol 2005;142:134-142.
    • (2005) Gen Comp Endocrinol , vol.142 , pp. 134-142
    • Weltzien, F.A.1    Pasqualini, C.2    Vernier, P.3    Dufour, S.4
  • 31
    • 0033571498 scopus 로고    scopus 로고
    • Synthesis of polyacrylamides N-substituted with PNA-like oligonucleotide mimics for molecular diagnostic applications
    • Efimov VA, Buryakova AA, Chakhmakhcheva OG. Synthesis of polyacrylamides N-substituted with PNA-like oligonucleotide mimics for molecular diagnostic applications. Nucleic Acids Res 1999; 27:4416-4426.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4416-4426
    • Efimov, V.A.1    Buryakova, A.A.2    Chakhmakhcheva, O.G.3
  • 32
    • 11144356184 scopus 로고    scopus 로고
    • The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation
    • Parker LH, Schmidt M, Jin SW, et al. The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature 2004;428:754-758.
    • (2004) Nature , vol.428 , pp. 754-758
    • Parker, L.H.1    Schmidt, M.2    Jin, S.W.3
  • 33
    • 16644391316 scopus 로고    scopus 로고
    • Downregulation of gene expression with negatively charged peptide nucleic acids (PNAs) in zebrafish embryos
    • Wickstrom E, Urtishak KA, Choob M, et al. Downregulation of gene expression with negatively charged peptide nucleic acids (PNAs) in zebrafish embryos. Methods Cell Biol 2004;77:137-158.
    • (2004) Methods Cell Biol , vol.77 , pp. 137-158
    • Wickstrom, E.1    Urtishak, K.A.2    Choob, M.3
  • 34
    • 79151470966 scopus 로고    scopus 로고
    • Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development
    • Gerety SS, Wilkinson DG. Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol 2011;350:279-289.
    • (2011) Dev Biol , vol.350 , pp. 279-289
    • Gerety, S.S.1    Wilkinson, D.G.2
  • 36
    • 3042512332 scopus 로고    scopus 로고
    • Cloning and developmental expression patterns of Dlx2, Lhx7 and Lhx9 in the medaka fish (Oryza latipes)
    • Alunni A, Blin M, Deschet K, Bourrat F, Vernier P, Rétaux S. Cloning and developmental expression patterns of Dlx2, Lhx7 and Lhx9 in the medaka fish (Oryza latipes). Mech Dev 2004;121:977-983.
    • (2004) Mech Dev , vol.121 , pp. 977-983
    • Alunni, A.1    Blin, M.2    Deschet, K.3    Bourrat, F.4    Vernier, P.5    Rétaux, S.6
  • 37
    • 33846456618 scopus 로고    scopus 로고
    • Developmental origin of diencephalic sensory relay nuclei in teleosts
    • Ishikawa Y, Yamamoto N, Yoshimoto M, et al. Developmental origin of diencephalic sensory relay nuclei in teleosts. Brain Behav Evol 2007;69:87-95.
    • (2007) Brain Behav Evol , vol.69 , pp. 87-95
    • Ishikawa, Y.1    Yamamoto, N.2    Yoshimoto, M.3
  • 38
    • 0032103757 scopus 로고    scopus 로고
    • Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye
    • Loosli F, Köster RW, Carl M, Krone A, Wittbrodt J. Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye. Mech Dev 1998;74:159-164.
    • (1998) Mech Dev , vol.74 , pp. 159-164
    • Loosli, F.1    Köster, R.W.2    Carl, M.3    Krone, A.4    Wittbrodt, J.5
  • 39
    • 76449099253 scopus 로고    scopus 로고
    • Functional and evolutionary insights into vertebrate kisspeptin systems from studies of fish brain
    • Akazome Y, Kanda S, Okubo K, Oka Y. Functional and evolutionary insights into vertebrate kisspeptin systems from studies of fish brain. J Fish Biol 2010;76:161-182.
    • (2010) J Fish Biol , vol.76 , pp. 161-182
    • Akazome, Y.1    Kanda, S.2    Okubo, K.3    Oka, Y.4
  • 40
    • 84866317800 scopus 로고    scopus 로고
    • Embryonic development of kisspeptin neurones in rat
    • Desroziers E, Droguerre M, Bentsen AH, et al. Embryonic development of kisspeptin neurones in rat. J Neuroendocrinol 2012;24: 1284-1295.
    • (2012) J Neuroendocrinol , vol.24 , pp. 1284-1295
    • Desroziers, E.1    Droguerre, M.2    Bentsen, A.H.3
  • 41
    • 33847622422 scopus 로고    scopus 로고
    • Developmental expression of the G protein-coupled receptor 54 and three GnRH mRNAs in the teleost fish cobia
    • Mohamed JS, Benninghoff AD, Holt GJ, Khan IA. Developmental expression of the G protein-coupled receptor 54 and three GnRH mRNAs in the teleost fish cobia. J Mol Endocrinol 2007;38:235-244.
    • (2007) J Mol Endocrinol , vol.38 , pp. 235-244
    • Mohamed, J.S.1    Benninghoff, A.D.2    Holt, G.J.3    Khan, I.A.4
  • 42
    • 62749203684 scopus 로고    scopus 로고
    • Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin- releasing hormone-1 neurons
    • Constantin S, Caligioni CS, Stojilkovic S, Wray S. Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin- releasing hormone-1 neurons. Endocrinology 2009;150: 1400-1412.
    • (2009) Endocrinology , vol.150 , pp. 1400-1412
    • Constantin, S.1    Caligioni, C.S.2    Stojilkovic, S.3    Wray, S.4
  • 43
    • 78149357363 scopus 로고    scopus 로고
    • Kisspeptin-10 inhibits bone-directed migration of GPR54-positive breast cancer cells: Evidence for a dose-window effect
    • Olbrich T, Ziegler E, Türk G, Schubert A, Emons G, Gründker C. Kisspeptin-10 inhibits bone-directed migration of GPR54-positive breast cancer cells: evidence for a dose-window effect. Gynecol Oncol 2010;119:571-578.
    • (2010) Gynecol Oncol , vol.119 , pp. 571-578
    • Olbrich, T.1    Ziegler, E.2    Türk, G.3    Schubert, A.4    Emons, G.5    Gründker, C.6
  • 44
    • 28544441746 scopus 로고    scopus 로고
    • Kisspeptin- 10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: A potential mechanism for the metastasis suppressor activity of kisspeptins
    • Navenot JM, Wang Z, Chopin m, Fujii N, Peiper SC. Kisspeptin- 10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins. Cancer Res 2005;65: 10450-10456.
    • (2005) Cancer Res , vol.65 , pp. 10450-10456
    • Navenot, J.M.1    Wang, Z.2    Chopin, M.3    Fujii, N.4    Peiper, S.C.5
  • 45
    • 50649118883 scopus 로고    scopus 로고
    • Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation
    • Mizoguchi T, Verkade H, Heath JK, Kuroiwa A, Kikuchi Y. Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation. Development 2008; 135: 2521-2529.
    • (2008) Development , vol.135 , pp. 2521-2529
    • Mizoguchi, T.1    Verkade, H.2    Heath, J.K.3    Kuroiwa, A.4    Kikuchi, Y.5
  • 46
    • 0032482926 scopus 로고    scopus 로고
    • Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
    • Ma Q, Jones D, Borghesani PR, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci USA 1998;95:9448-9453.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9448-9453
    • Ma, Q.1    Jones, D.2    Borghesani, P.R.3
  • 47
    • 0032104460 scopus 로고    scopus 로고
    • A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: Their functions in development, hematopoiesis and HIV infection
    • Nagasawa T, Tachibana K, Kishimoto T. A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection. Semin Immunol 1998;10: 179-185.
    • (1998) Semin Immunol , vol.10 , pp. 179-185
    • Nagasawa, T.1    Tachibana, K.2    Kishimoto, T.3
  • 48
    • 77955921238 scopus 로고    scopus 로고
    • Human kisspeptins activate neuropeptide FF2 receptor
    • Lyubimov Y, Engstrom M, Wurster S, et al. Human kisspeptins activate neuropeptide FF2 receptor. Neuroscience 2010;170:117-122.
    • (2010) Neuroscience , vol.170 , pp. 117-122
    • Lyubimov, Y.1    Engstrom, M.2    Wurster, S.3
  • 49
    • 78651519422 scopus 로고    scopus 로고
    • Activation of neuropeptide FF Receptors by kisspeptin receptor ligands
    • Oishi S, Misu R, Tomita K, et al. Activation of neuropeptide FF Receptors by kisspeptin receptor ligands. ACS Med Chem Lett 2011;2:53-57.
    • (2011) ACS Med Chem Lett , vol.2 , pp. 53-57
    • Oishi, S.1    Misu, R.2    Tomita, K.3
  • 50
    • 79960758876 scopus 로고    scopus 로고
    • Female reproductive maturation in the absence of kisspeptin/GPR54 signaling
    • Mayer C, Boehm U. Female reproductive maturation in the absence of kisspeptin/GPR54 signaling. Nat Neurosci 2011;14:704-710.
    • (2011) Nat Neurosci , vol.14 , pp. 704-710
    • Mayer, C.1    Boehm, U.2
  • 51
    • 76449111890 scopus 로고    scopus 로고
    • Hypothalamic Kiss1 but not Kiss2 neurons are involved in estrogen feedback in medaka (Oryza latipes)
    • Mitani Y, Kanda S, Akazome Y, Zempo B, Oka Y. Hypothalamic Kiss1 but not Kiss2 neurons are involved in estrogen feedback in medaka (Oryza latipes). Endocrinology 2010;151:1751-1759.
    • (2010) Endocrinology , vol.151 , pp. 1751-1759
    • Mitani, Y.1    Kanda, S.2    Akazome, Y.3    Zempo, B.4    Oka, Y.5
  • 52
    • 79953184987 scopus 로고    scopus 로고
    • Organization of two independent kisspeptin systems derived from evolutionary-ancient kiss genes in the brain of zebrafish
    • Servili A, Le Page Y, Leprince J, et al. Organization of two independent kisspeptin systems derived from evolutionary-ancient kiss genes in the brain of zebrafish. Endocrinology 2011;152:1527-1540.
    • (2011) Endocrinology , vol.152 , pp. 1527-1540
    • Servili, A.1    Le Page, Y.2    Leprince, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.