Beyond lipid lowering: Pleiotropic effects of statins in heart failure

Netherlands Heart Journal

Volumn 21, Issue 9, 2013, Pages 406-407

  Swenne, C A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; FARNESYL DIPHOSPHATE; GERANYLGERANYL PYROPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PLACEBO; RAC PROTEIN; RAS PROTEIN; RHO FACTOR; ROSUVASTATIN; SELENOPROTEIN;

ACUTE CORONARY SYNDROME; AUTOIMMUNE DISEASE; CARDIOMYOPATHY; CLINICAL TRIAL (TOPIC); EDITORIAL; FIBROBLAST; GRAFT PATENCY; HEART FAILURE; HEART MUSCLE; IN-STENT RESTENOSIS; NEOPLASM; PLEIOTROPY; PREECLAMPSIA; PRENYLATION; SEPSIS; TISSUE DOPPLER IMAGING; WOUND HEALING;

EID: 84883176038     PISSN: 15685888     EISSN: 18766250     Source Type: Journal    
DOI: 10.1007/s12471-013-0460-5     Document Type: Editorial

References (22)

1. Bonsu KO, Kadirvelu A, Reidpath DD. Statins in heart failure: do we need another trial? Vasc Health Risk Manag. 2013;9:303-319.
2. Porter KE, Turner NA. Statins and myocardial remodelling: cell and molecular pathways. Expert Rev Mol Med. 2011;13:e22.
3. Xu H, Yang YJ, Yang T, et al. Statins and stem cell modulation. Ageing Res Rev. 2013;12(1):1-7.
4. Mihos CG, Artola RT, Santana O. The pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in rheumatologic disorders: a comprehensive review. Rheumatol Int. 2012;32(2):287-294.
5. Farsaei S, Khalili H, Farboud ES. Potential role of statins on wound healing: review of the literature. Int Wound J. 2012;9(3):238-247.
6. Lopez-Pedrera C, Ruiz-Limon P, Valverde-Estepa A, et al. To cardiovascular disease and beyond: new therapeutic perspectives of statins in autoimmune diseases and cancer. Curr Drug Targets. 2012;13(6):829-841.
7. Luo J,Xu L, Yu T, et al. Effect of statins therapy prior to percutaneous coronary intervention. J Interv Cardiol. 2012;25(2):156-162.
8. Prasad K. Do statins have a role in reduction/prevention of post-PCI restenosis? Cardiovasc Ther. 2013;31(1):12-26.
9. Sposito AR, Aguiar Filho GB, Aarao AR, et al. Statins in acute coronary syndromes. Arq Bras Cardiol. 2011;97(4):350-356.
10. Margaritis M, Channon KM, Antoniades C. Statins and vein graft failure in coronary bypass surgery. Curr Opin Pharmacol. 2012;12(2):172-180.
11. Sanchez MA, Thomas CB, O'Neal HR. Do aspirin and statins prevent severe sepsis? Curr Opin Infect Dis. 2012;25(3):345-350.
12. Lecarpentier E, Morel O, Fournier T, et al. Statins and pregnancy: between supposed risks and theoretical benefits. Drugs. 2012;72(6):773-788.
13. Gastelurrutia P, Lupon J, de Antonio M, et al. Statins in heart failure: the paradox between large randomized clinical trials and real life. Mayo Clin Proc. 2012;87(6):555-560.
14. Rauchhaus M, Clark AL, Doehner W, et al. The relationship between cholesterol and survival in patients with chronic heart failure. J Am Coll Cardiol. 2003;42(11):1933-1940.
15. Treasure CB, Klein JL, Weintraub WS, et al. Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med. 1995;332(8):481-487.
16. Mortensen SA, Leth A, Agner E, et al. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med. 1997;18(Suppl):S137-S144.
17. Moosmann B, Behl C. Selenoprotein synthesis and side-effects of statins. Lancet. 2004;363(9412):892-894.
18. Bonsu KO, Kadirvelu A, Reidpath DD. Lipophilic versus hydrophil-ic statin therapy for heart failure: a protocol for an adjusted indirect comparison meta-analysis. Syst Rev. 2013;2:22.
19. Kjekshus J, Apetrei E, Barrios V, et al. Rosuvastatin in older patients with systolic heart failure. N Engl J Med. 2007;357(22):2248-2261.
20. Tavazzi L, Maggioni AP, Marchioli R, et al. Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet. 2008;372(9645):1231-1239.
21. Gastelurrutia P, Lupon J, Bayes-Genis A. Statins in heart failure: not yet the end of the story? Eur J Heart Fail. 2013;15(6):708-709.
22. Correale M, Totaro A, Passero T, et al. Treatment with atorvastatin is associated with a better prognosis in chronic heart failure with systolic dysfunction: results from The Daunia Heart Failure Registry. Neth Heart J. 2013. doi:10.1007/s12471-013-0430-y.