Prostaglandin reductase-3 negatively modulates adipogenesis through regulation of PPARγ activity

Journal of Lipid Research

Volumn 54, Issue 9, 2013, Pages 2391-2399

  Yu, Yu Hsiang ^a   Chang, Yi Cheng ^a,b   Su, Tseng Hsiung ^b   Nong, Jiun Yi ^a   Li, Chao Chin ^c   Chuang, Lee Ming ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c ACADEMIA SINICA   (Taiwan)

Author keywords

Adipocyte differentiation; Eicosanoid; Ligand; Nuclear receptor

Indexed keywords

13,14 DIHYDRO 15 KETO PROSTAGLANDIN E2; 15 KETO PROSTAGLANDIN E2; 15 OXOPROSTAGLANDIN 13 REDUCTASE; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN E2 DERIVATIVE; PROSTAGLANDIN REDUCTASE 3; UNCLASSIFIED DRUG;

ADIPOGENESIS; ARTICLE; CELL DIFFERENTIATION; CELL LEVEL; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME REGULATION; GENE SILENCING; IN VITRO STUDY; METABOLIC DISORDER; MITOSIS INHIBITION; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; RECEPTOR UPREGULATION; TRANSIENT TRANSFECTION;

ADIPOCYTE DIFFERENTIATION; EICOSANOID; LIGAND; NUCLEAR RECEPTOR;

ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE, WHITE; ADIPOSITY; ANIMALS; CELL LINE; DINOPROSTONE; MICE; OBESITY; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PPAR GAMMA;

EID: 84883171449     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M037556     Document Type: Article

References (18)

1. Forman, B. M., P. Tontonoz, J. Chen, R. P. Brun, B. M. Spiegelman, and R. M. Evans. 1995. 15-deoxy- - 12.14 -prostaglandin J 2 is a ligand for the adipocyte determination factor PPAR -α. Cell. 83: 803-812.
2. Chou, W. L., L. M. Chuang, C. C. Chou, A. H. Wang, J. A. Lawson, G. A. FitzGerald, and Z. F. Chang. 2007. Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation. J. Biol. Chem. 282: 18162-18172.
3. Yokomizo, T., Y. Ogawa, N. Uozumi, K. Kume, T. Izumi, and T. Shimizu. 1996. cDNA cloning, expression, and mutagenesis study of leukotriene B4 12-hydroxydehydrogenase. J. Biol. Chem. 271: 2844-2850.
4. Zhao, Y., C. C. Weng, M. Tong, J. Wei, and H. H. Tai. 2010. Restoration of leukotriene B 4 -12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo. Lung Cancer. 68: 161-169.
5. Tai, H. H., C. M. Ensor, M. Tong, H. Zhou, and F. Yan. 2002. Prostaglandin catabolizing enzymes. Prostaglandins Other Lipid Mediat. 68-69: 483-493.
6. Fajas, L., S. Miard, M. R. Briggs, and J. Auwerx. 2003. Selective cyclooxygenase- 2 inhibitors impair adipocyte differentiation through inhibition of the clonal expansion phase. J. Lipid Res. 44: 1652-1659.
7. Ghoshal, S., D. B. Trivedi, G. A. Graf, and C. D. Loftin. 2011. Cyclooxygenase-2 deficiency attenuates adipose tissue differentiation and inflammation in mice. J. Biol. Chem. 286: 889-898.
8. Fujimori, K., K. Aritake, and Y. Urade. 2007. A novel pathway to enhance adipocyte differentiation of 3T3-L1 cells by up-regulation of lipocalin-type prostaglandin D synthase mediated by liver X receptor-activated sterol regulatory element-binding potein-1c. J. Biol. Chem. 282: 18458-18466.
9. Ragolia, L., T. Palaia, C. E. Hall, J. K. Maesaka, N. Eguchi, and Y. Urade. 2005. Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice. J. Biol. Chem. 280: 29946-29955.
10. Mazid, M. A., A. A. Chowdhury, K. Nagao, K. Nishimura, M. Jisaka, T. Nagaya, and K. Yokota. 2006. Endogenous 15-deoxy- - 12.14 - prostaglandin J 2 synthesized by adipocytes during maturation phase contributes to upregulation of fat storage. FEBS Lett. 580: 6885-6890.
11. Bell-Parikh, L. C., T. Ide, J. A. Lawson, P. McNamara, M. Reilly, and G. A. FitzGerald. 2003. Biosynthesis of 15-deoxy- - 12.14 -PGJ2 and the ligation of PPAR -α. J. Clin. Invest. 112: 945-955.
12. Liu, L., and N. A. Clipstone. 2007. Prostaglandin F2 - inhibits adipocyte differentiation via a G - q-calcium-calcineurin-dependent signaling pathway. J. Cell. Biochem. 100: 161-173.
13. Fujimori, K., T. Ueno, N. Nagata, K. Kashiwagi, K. Aritake, F. Amano, and Y. Urade. 2010. Suppression of adipocyte differentiation by aldo-keto reductase 1B3 acting as prostaglandin F2alpha synthase. J. Biol. Chem. 285: 8880-8886.
14. Ueno, T., and K. Fujimori. 2011. Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2 - receptor mediated activation of MEK/ERK-CREB cascade. FEBS J. 278: 2901-2912.
15. Hyman, B. T., L. L. Stoll, and A. A. Spector. 1982. Prostaglandin production by 3T3-L1 cells in culture. Biochim. Biophys. Acta. 713: 375-385.
16. Anggard, E., C. Larsson, and B. Samuelsson. 1971. The distribution of 15-hydroxy prostaglandin dehydrogenase and prostaglandindelta 13-reductase in tissues of the swine. Acta Physiol. Scand. 81: 396-404.
17. Moon, Y. S., C. M. Smas, K. Lee, J. A. Villena, K. H. Kim, E. J. Yun, and H. S. Sul. 2002. Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity. Mol. Cell. Biol. 22: 5585-5592.
18. Ross, S. E., N. Hemati, K. A. Longo, C. N. Bennett, P. C. Lucas, R. L. Erickson, and O. A. MacDougald. 2000. Inhibition of adipogenesis by Wnt signaling. Science. 289: 950-953.