A randomized, double-blinded, placebo-controlled trial of oral polypodium leucotomos extract as an adjunct to sunscreen in the treatment of melasma

JAMA Dermatology

Volumn 149, Issue 8, 2013, Pages 981-983

  Ahmed, Ammar M ^a,b   Lopez, Isha ^a   Perese, Francisco ^a   Vasquez, Rebecca ^a   Hynan, Linda S ^a   Chong, Benjamin ^a   Pandya, Amit G ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROQUINONE; PLACEBO; POLYPODIUM LEUCOTOMOS EXTRACT; SALICYLIC ACID; SUNSCREEN;

ADULT; AGED; CHLOASMA; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; MORNING DOSAGE; POLYPODIUM; POLYPODIUM LEUCOTOMOS; PRIORITY JOURNAL; RADIATION PROTECTION; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; ULTRAVIOLET RADIATION;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; DOUBLE-BLIND METHOD; FEMALE; HISPANIC AMERICANS; HUMANS; MELANOSIS; PLANT EXTRACTS; POLYPODIUM; SUNSCREENING AGENTS; TREATMENT OUTCOME;

EID: 84883162604     PISSN: 21686068     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamadermatol.2013.4294     Document Type: Letter

References (4)

1. Haddad AL, Matos LF, Brunstein F, Ferreira LM, Silva A, Costa D Jr. A clinical, prospective, randomized, double-blind trial comparing skin whitening complex with hydroquinone vs. placebo in the treatment of melasma. Int J Dermatol. 2003;42(2):153-156.
2. Rendon M, BerneburgM, Arellano I, Picardo M. Treatment of melasma. J Am Acad Dermatol. 2006;54(5)(suppl 2):S272-S281.
3. Lakhdar H, Zouhair K, Khadir K, et al. Evaluation of the effectiveness of a broad-spectrum sunscreen in the prevention of chloasma in pregnant women. J Eur Acad Dermatol Venereol. 2007;21(6):738-742.
4. Kodali S, Guevara IL, Carrigan CR, et al. A prospective, randomized, split-face, controlled trial of salicylic acid peels in the treatment of melasma in Latin American women. J AmAcad Dermatol. 2010;63(6):1030-1035.