5,6,7,8-Tetrahydropyrido[4,3- c ]pyridazine: A lead-oriented scaffold with two diversity points

Synthesis (Germany)

Volumn 45, Issue 17, 2013, Pages 2413-2416

  Borisov, Alexander V ^a   Voloshchuk, Volodymyr V ^a,b   Nechayev, Maxim A ^c   Grygorenko, Oleksandr O ^d  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

^b NATIONAL TECHNICAL UNIVERSITY OF UKRAINE   (Ukraine)

^c NATIONAL UNIVERSITY OF PHARMACY   (Ukraine)

^d TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

lead oriented synthesis; nitrogen heterocycles; nucleophilic substitution; piperidine; pyridazine

Indexed keywords

GLYOXYLIC ACIDS; NITROGEN HETEROCYCLES; NUCLEOPHILIC SUBSTITUTIONS; ONE POT; PIPERIDINE; PYRIDAZINE; SOLVENT FREE REACTION; TARGET COMPOUND;

SCAFFOLDS; SYNTHESIS (CHEMICAL);

PYRIDINE;

5,6,7,8 TETRAHYDROPYRIDO[4,3 C]PYRIDAZIN 3 AMINE; 5,6,7,8 TETRAHYDROPYRIDO[4,3 C]PYRIDAZINE DERIVATIVE; ALKYL 3 CHLORO 7,8 DIHYDROPYRIDO[4,3 C]PYRIDAZINE 6(5H) CARBOXYLIC ACID; ALKYL 3 OXO 3,5,7,8 TETRAHYDROPYRIDO[4,3 C]PYRIDAZINE 6(2H) CARBOXYLIC ACID; BENZYL 3 CHLORO 7,8 DIHYDROPYRIDO[4,3 C]PYRIDAZINE 6(5H) CARBOXYLIC ACID; BENZYL 3 OXO 3,5,7,8 TETRAHYDROPYRIDO[4,3 C]PYRIDAZINE 6(2H) CARBOXYLIC ACID; ETHYL 3 (METHYLAMINO) 7,8 DIHYDROPYRIDO[4,3 C]PYRIDAZINE CARBOXYLIC ACID; ETHYL 3 AMINO 7,8 DIHYDROPYRIDO[4,3 C]PYRIDAZINE 6(5H) CARBOXYLIC ACID; ETHYL 3 CHLORO 7,8 DIHYDROPYRIDO[4,3 C]PYRIDAZINE 6(5H) CARBOXYLIC ACID; ETHYL 3 OXO 3,5,7,8 TETRAHYDROPYRIDO[4,3 C]PYRIDAZINE 6(2H) CARBOXYLIC ACID; GLYOXYLIC ACID; HYDRAZINE; MOLECULAR SCAFFOLD; N METHYL 5,6,7,8 TETRAHYDROPYRIDO[4,3 C]PYRIDAZIN 3 AMINE; PIPERIDONE DERIVATIVE; PYRIDAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DEPROTECTION REACTION; DERIVATIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ONE POT SYNTHESIS;

EID: 84883134481     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1339325     Document Type: Article

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