The underlying aetiologies of coma in febrile sudanese children

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 107, Issue 5, 2013, Pages 307-312

  El Amin, Eisa O ^a   Haj Elbashir, Mohamed I ^b   Elamin, Osman E ^a   Mukhtar, Yousif ^a   Abdo, Hussein ^a   Abdul Rahman, Ismail ^a   El Amina, Mohamed E ^a  

^a NATIONAL RIBAT UNIVERSITY   (Sudan)

^b Sudan Medical Specialization Board ^*  (Sudan)

Author keywords

Altered consciousness; Fever; Sudanese children

Indexed keywords

ACICLOVIR; ARTEMETHER; CEFTRIAXONE;

ARTICLE; BACTERIAL MENINGITIS; BRAIN MALARIA; CHILD; CLINICAL FEATURE; COMA; CONSCIOUSNESS DISORDER; EMERGENCY WARD; FEVER; HAEMOPHILUS INFLUENZAE; HEMATOLOGICAL PARAMETERS; HERPES SIMPLEX ENCEPHALITIS; HOSPITAL ADMISSION; HUMAN; LABORATORY TEST; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MIXED INFECTION; STREPTOCOCCUS PNEUMONIAE; SUDAN; TERTIARY HEALTH CARE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; COMA; DIAGNOSIS, DIFFERENTIAL; ENCEPHALITIS, VIRAL; FEMALE; FEVER; HUMANS; INFANT; MALARIA, CEREBRAL; MALE; MENINGITIS, BACTERIAL; PROSPECTIVE STUDIES; SUDAN;

EID: 84883121573     PISSN: 00359203     EISSN: 18783503     Source Type: Journal    
DOI: 10.1093/trstmh/trt013     Document Type: Article

References (55)

1. Warrell D, Molyneux M, Beales P. Severe and complicated malaria. Trans R Soc Trop Med Hyg 1990;84(Suppl 2):1-65.
2. Marsh K, Forster D, Waruiru C et al. Indicators of life-threatening malaria in African children. N Engl J Med 1996;332:1399-404.
3. WHO. Severe falciparum malaria. Trans R Soc Trop Med Hyg 2000;94(Suppl 1):S1-S90.
4. Hein TT, Day NP, Nguyen HP et al. A controlled trial of artemether or quinine in Vietnamese adults with severe falciparum malaria. N Engl J Med 1996;335:76-83.
5. McCutchan TF, Piper RC, Makler MT. Use of malaria rapid diagnostic test to identify Plasmodium knowlesi infection. Emerg Infect Dis 2008;14:1750-2
6. WHO Guidelines for the treatment of malaria. 2nd ed. Geneva: World Health Organization; 2010.
7. Petti CA, Polage CR, Quinn TC et al. Laboratory medicine in Africa: a barrier to effective health care. Clin Infect Dis 2006;42:377-82
8. English M, Esamai F, Wasunna A et al Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya. Lancet 2004;363:1948-53.
9. Zurovac D, Midia B, Ochola SA et al. Microscopy and outpatient malaria case management among older children and adults in Kenya. Trop Med Int Health 2006;11:432-40.
10. Wright P, Avery W, Ardill W, McLarty J. Initial clinical assessment of the comatose patient: cerebral malaria vs. meningitis. J Ped Inf Dis 1993;12:37-41
11. Solomon T Flavivirus encephalitis. N Engl J Med 2004;351:370-8.
12. Warhurst DC, Williams JE. Laboratory diagnosis of malaria. J Clin Pathol 1996;49:533-8
13. Crawley J, Smith S, Kirkham F et al. Seizure and status epilepticus in childhood cerebral malaria. QJM 1996;89:591-7.
14. Molyneux M, Taylor T, Wirama J, Borgstein A. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. QJ Med 1989;71:441-59.
15. Reyburn H, Mbakilwa H, Mwangi R et al. Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomized trial. BMJ 2007;10:307-11.
16. Marx A, Pewsner D, Egger M et al. Meta-analysis: accuracy of rapid tests for malaria in travelers returning from endemic areas. Ann Intern Med 2005;142:836-46.
17. Laferl H, Kandel K, Pichler H. False positive dipstick test for malaria. N Engl J Med 1997;337:1635-6.
18. Reyburn H, Mbatia R, Drakeley C et al. Over diagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study. BMJ 2004;329:1212.
19. Makani J, Matuja W, Liyombo E et al. Admission diagnosis of cerebral malaria in adults in an endemic area of Tanzania: implications and clinical description. QJM 2003;96:355-62.
20. Chipipa J, Kolczak M, Sukwa T. Does the availability of blood slide microscopy for malaria at health centers improve the management of persons with fever in Zambia? Am J Trop Med Hyg 1999;60:1024-30.
21. Andrej Trampuz, Matjaz Jereb, Igor Muzlovic, Rajesh M Prabhu. Clinical review: Severe malaria. Critical Care 2003;7:315-23.
22. Smith T, Schellenberg JA, Hayes R. Attributable fraction estimates and case definitions for malaria in endemic areas. Stat Med 1994;13:2345-58.
23. Bejon P, Berkley JA, Mwangi T et al. Defining childhood severe falciparum malaria for intervention studies. PLoS Med 2007;4:251-5.
24. Njuguna PW, Newton CR. Management of severe falciparum malaria. J Postgrad Med 2004;50:45-50.
25. Schapira A, Trigg P, Renganathan E et al. Management of severe malaria: a practical handbook. 2nd ed. Geneva: World Health Organization; 2000.
26. Berkley JA, Ross A, Wangi I et al. Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study. BMJ 2003;326:36.
27. Idro R, Jenkins NE, Newton CR. Pathogenesis, clinical features, and neurological outcome of cerebral malaria. Lancet Neurol 2005;4:827-40.
28. Newton CR, Kirkham F, Winstanley PA et al. Intracranial pressure in African children with cerebral malaria. Lancet 1991;337:573-6.
29. Berkley JA, Maitland K, Mwangi I et al. Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study. BMJ 2005;330:995.
30. Ministry of Health. Statistics Bulletin (2010). Health Information Department. Ministry of Health: Khartoum, Sudan; 2011.
31. Ministry of Health. Health Information Department Publications (Protocols in Paediatrics). Khartoum, Sudan: Ministry of Health; 2009.
32. Dillip Angel. Gaining access to prompt and appropriate malaria treatment in the Kilombero valley, Tanzania: a health social science perspective. University of Basel: Faculty of Science; 2012 p. 24-6.
33. Bennet S, Myatt M, Jolley D, Radalowicsz A. Data Management for Surveys and Trials. A Practical Primer Using Epi Info. Llanidloes Powsys: Brixton Books; 1994.
34. Simon D, Boring JR III. Sensitivity, Specificity, and Predictive Value. In: Clinical Methods: The History, Physical, and Laboratory Examinations. Walker HK, Hall WD, Hurst JW, editors. 3rd ed. 1990; Atlanta: Butterworths; p. 30-2.
35. Brewster DR, Kwiatkowski D, White NJ. Neurological sequelae of cerebral malaria in children. Lancet. 1990;336:1039-43.
36. World Malaria Report. Global Strategic Plan: Roll Back Malaria 2005-2015. Geneva: Roll Back Malaria Partnership, World Health Organization; 2005.
37. Akpede GO, Sykes RM. Malaria with bacteraemia in acutely febrile preschool children without localizing signs: coincidence or association/complication? J Trop Med Hyg 1993;96:146-50.
38. Ministry of Health. Manual for Treatment of Malaria and its Complications. Sultanate of Oman: Ministry of Health Publications; 1996.
39. Ochola LB, Vounatsou P, Smith T et al. The reliability of diagnostic techniques in the diagnosis and management of malaria in the absence of a gold standard. Lancet Infect Dis 2006;6:582-8.
40. Guerrant RL, Walker DH, Weller PF. Tropical Infectious Diseases: Principles, Pathogens, and Practice. 2nd ed. Philadelphia: Elsevier Churchill Livingstone; 2006
41. Straus SE, Thorpe KE, Holroyd-Leduc J. How do I perform a lumbar puncture and analyze the results to diagnose bacterial meningitis? JAMA 2006;296:2012-22.
42. Campagne G, Schuchat A, Djibo S et al. Epidemiology of bacterial meningitis in Niamey, Niger, 1981-96. Bull World Health Organ 1999;77:499-508.
43. Yaro S, Lourd M, Naccro B et al. The epidemiology of Haemophilus influenzae type b meningitis in Burkina Faso. Pediatr Infect Dis J 2006; 25:415-9.
44. Sejvar JJ. The evolving epidemiology of viral encephalitis. Curr Opin Neurol 2006;19:350-7.
45. Reschmutzhard E, Gerstenbrand F. Cerebral malaria in Tanzania. It's epidemiology, clinical symptoms and neurological long term sequelae in the light of 66 cases. Trans R Soc Trop Med Hyg 1984;78:351-3.
46. WHO. Malaria global fund proposal development: compilation of WHO reference document, July 2011. Geneva: World Health Organization. WHO/GMP July 2011:7.
47. Rougement A, Breslow N, Brenner E et al. Epidemiological basis for clinical diagnosis of childhood malaria in endemic zone in West Africa. Lancet ;338:1292-5.
48. Kariuki SM, Ikumi M, Ojal J et al. Acute seizure attributable to falciparum malaria in an endemic area on the Kenyan coast. Brain 2011:1519-28
49. Misra UK, Tan CT, Kalita J. Seizures in encephalitis: neurology. Asia; 2008;13:1-13.
50. Millner M Complicated febrile convulsion vs. herpes encephalitis. Pediatr Padol 1993;28:A7-9.
51. Annegers JF, Hauser WA, Beghi E et al. The risk of unprovoked seizures after encephalitis and meningitis. Neurology 1988;38:1407.
52. Van den Ende J, Van Gompel A, Lynen L et al. Clinical algorithm for malaria in Africa. Lancet 1996;347:1327.
53. Ladhani S, Lowe B, Cole AO et al. Changes in white blood cells and platelets in children with falciparum malaria: Relationship to disease outcome. Br J Haematol 2002;119:839-47.
54. Rogier C, Gerardin P, Imbert P. Thrombocytopenia is predictive of lethality in severe childhood falciparum malaria. Arch Dis Child 2004;89:795-96
55. Taylor TE, Fu WJ, Carr RA et al Differentiating the pathologies of cerebral malaria by postmortem parasite counts. Nat Med 2004;10:143-5.