Drug-loaded cubic micro-chamber made of a biodegradable polymer for bacteria-based drug delivery

8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013

Volumn , Issue , 2013, Pages 1141-1144

  Yoo, Hyung Jung ^a   Lee, Sangmin ^a   Ahn, Jae Hyun ^a   Cho, Dong Il ^a  

^a Seoul National University   (South Korea)

Author keywords

bacteria; biodegradable polymer; drug delivery system; microfabrication; x ray lithography

Indexed keywords

CONVENTIONAL PHOTOLITHOGRAPHY; CUBIC STRUCTURE; DRUG DELIVERY SYSTEM; FOOD AND DRUG ADMINISTRATION; INK-JET PRINTING METHOD; LITHOGRAPHY PROCESS; MICRO-CHAMBERS; MICRO-MACHINED;

BACTERIA; BIOCOMPATIBILITY; DRUG DELIVERY; LITHOGRAPHY; MICROFABRICATION; X RAY LITHOGRAPHY;

BIODEGRADABLE POLYMERS;

EID: 84883103786     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NEMS.2013.6559923     Document Type: Conference Paper

References (21)

1. Jung-Joon Min, Vu H Nguyen, Hyun-Ju Kim, Yeongjin Hong, and Hyon E Choy, "Quantitative bioluminescence imaging of tumor-targeting bacteria in living animals," Nature Protocols, vol 3, no 4, 2008, pp. 629-636.
2. B. Behkam, and M. Sitti, "Effect of quantity and configuration of attached bacteria on bacterial propulsion of microbeads," Applied Physics Letters, vol. 93, 2008, pp. 223901.
3. Park, S. J., et al., "Motility enhancement of bacteria actuated microstructures using selective bacteria adhesion," Lab on a Chip, vol. 10, no. 13, 2010, pp. 1706-1711.
4. Hong, S. J., et al., "Biodegradable Polymer Droplet for Efficient Drug Delivery Using Flagellated Bacteria," 10th IEEE Int. Conf. Nano 2010, 2010, pp. 1072-1075.
5. http://www. teresewinslow. com/index. asp
6. Lee, S. M., Hong, S. J., Yoo, H. J., and Cho, D. I., "Surface Energy Modification of Biodegradable Polymeric Surfaces for Selective Bacterial Adhesion for Directional Locomotion in Chemotactic Targeted Drug Delivery," Proc. of ISMM 2011, 2011, pp. T3-070.
7. Shum, H. C., Kim, J. W., and D. Weitz, "Microfluidic Fabrication of Monodisperse Biocompatible and Biodegradable Polymersomes with Controlled Permeability," Journal of the American Chemical Society, vol. 130, no. 29, 2008, pp. 9543-9549.
8. Deniz K. Armani, and Chang Liu, "Microfabrication Technology for Polycaprolactone, A Biodegradable Polymer," Proc. MEMS 2000, 2000, pp. 294-299.
9. Say Chye Joachim Loo, Chui Ping Ooi, and Yin Chiang Freddy Boey, "Radiation effects on poly(lactide-co-glycolide) (PLGA) and poly(llactide) (PLLA)," Polymer Degradation and Stability, vol. 83, 2004, pp. 259-265.
10. Dietmar W. Hutmacher, "Scaffolds in tissue engineering bone and cartilage," Biomaterials, vol. 21, no. 15, 2000, pp. 2529-2543.
11. L. D. Shea, D. Wang, R. T. Franceschi, and D. J. Mooney "Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds," Tissue Eng, vol. 6, 2000, pp. 605-617.
12. http://pal. postech. ac. kr/
13. J. Klein, H. Guckel, D. P. Siddons, and E. D. Johnson, "X-ray masks for very deep X-ray lithography," Microsystem Technologies, vol. 4, no. 2, 1998, pp. 70-73.
14. Lee, B. K., "Development of Micro Mold Systems via LIGA technology for a Fabrication of Microstructures with Complicated Geometry," Pohang University of Science and Technology, 2009.
15. O. Schmalz, M. Hess, and R. Kosfeld, "Structural changes in poly(methylmethacrylate) during deep-etch X-ray synchrotron radiation lithography. Part II: Radiation effects on PMMA," Die Angewandte Makromolekulare Chemie, vol. 239, no. 1, 1996, pp. 79-91.
16. O. Schmalz, M. Hess, and R. Kosfeld, "Structural changes in poly(methylmethacrylate) during deep-etch X-ray synchrotron radiation lithography. Part III: Mode of action of the developer," Die Angewandte Makromolekulare Chemie, vol. 239, no. 1, 1996, pp. 93-106.
17. Dark Cam, Hyon, S. H., and Yoshito Ikada, "Degradation of high molecular weight poly(L-lactide) in alkaline medium," Biomoterials, vol. 16, 1995, pp. 833-843.
18. Yigui, Li., and SScusumu, S., "X-ray lithography fabrication of Poly-LLactides microstructures," International Symposium on Micro-NanoMechatronics and Human Science 2006, 2006, pp. 1-4.
19. Chou, M. C., Pan, C. T., Wu, T. T., and Wu, C. T., "Study of deep X-ray lithography behaviour for microstructures," Sensors and Actuators A, vol. 141, no. 2, 2008, pp. 703-711.
20. Chung, S. J., Jeong, J. W., Kim, W. H., Park, W. H., Lee, C. H., and Hong, Y. T., "Contact Resistance of Inkjet-Printed Silver Source-Drain Electrodes in Bottom-Contact OTFTs," Journal of Display Technology, vol. 8, no. 1, 2012, pp. 48-53.
21. Yoo, H. J., Hong, S. J., Lee, S. M., Ahn, J. H., and Cho, D. I., "Fabrication of Laminated Biodegradable Polymeric Structure for Controlled Drug Release," Proc. of KMEMS 2012, 2012, pp. FP-2-39.