Multifocal radiculoneuropathy during ipilimumab treatment of melanoma

Muscle and Nerve

Volumn 48, Issue 3, 2013, Pages 440-444

  Manousakis, Georgios ^a   Koch, James ^b   Sommerville, R Brian ^a   El Dokla, Ahmed ^d   Harms, Matthew B ^a   Al Lozi, Muhammad T ^a   Schmidt, Robert E ^c   Pestronk, Alan ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boone Hospital Center   (United States)

^c WASHINGTON UNIVERSITY   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Immune neuropathy; Ipilimumab; Peripheral nervous system vasculitis; Polyradiculopathy; Toxic neuropathy

Indexed keywords

IPILIMUMAB; METHYLPREDNISOLONE;

ADULT; ARTICLE; CASE REPORT; CEREBROSPINAL FLUID; CLINICAL FEATURE; DIPLOPIA; DISEASE COURSE; DISEASE SEVERITY; DIZZINESS; DORSAL ROOT; DRUG WITHDRAWAL; DYSPHAGIA; ELECTROMYOGRAM; HUMAN; LEG PAIN; LIMB WEAKNESS; MALE; MELANOMA; MOTOR NERVE BLOCK; NAUSEA AND VOMITING; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; NEUROPATHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL NERVE; PLASMAPHERESIS; POLYRADICULONEUROPATHY; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; RETROSPECTIVE STUDY; SPINE RADIOGRAPHY; TINNITUS; VENTRAL ROOT; WALKING DIFFICULTY;

IMMUNE NEUROPATHY; IPILIMUMAB; PERIPHERAL NERVOUS SYSTEM VASCULITIS; POLYRADICULOPATHY; TOXIC NEUROPATHY;

ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CRANIAL NERVES; ELECTROMYOGRAPHY; HUMANS; IMMUNOLOGIC FACTORS; MAGNETIC RESONANCE IMAGING; MALE; MELANOMA; NEURAL CONDUCTION; POLYRADICULONEUROPATHY; RECEPTORS, CELL SURFACE; SKIN NEOPLASMS; SURAL NERVE; TIME FACTORS;

EID: 84883053806     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.23830     Document Type: Article

References (25)

1. Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363:711-723.
2. Wolchok JD, Neyns B, Linette G, Negrier S, Lutzky J, Thomas L, et al. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 2010;11:155-164.
3. Di Giacomo AM, Biagioli M, Maio M. The emerging toxicity profiles of anti-CTLA-4 antibodies across clinical indications. Semin Oncol 2010;37:499-507.
4. Hunter G, Voll C, Robinson CA. Autoimmune inflammatory myopathy after treatment with ipilimumab. Can J Neurol Sci 2009;36:518-520.
5. Bhatia S, Huber BR, Upton MP, Thompson JA. Inflammatory enteric neuropathy with severe constipation after ipilimumab treatment for melanoma: a case report. J Immunother 2009;32:203-205.
6. Wilgenhof S, Neyns B. Anti-CTLA-4 antibody-induced Guillain-Barré syndrome in a melanoma patient. Ann Oncol 2011;22:991-993.
7. Pestronk A, Lopate G, Kornberg AJ, Elliot JL, Blume G, Yee WC, et al. Distal lower motor neuron syndrome with high-titer serum IgM anti-GM1 antibodies: improvement following immunotherapy with monthly plasma exchange and intravenous cyclophosphamide. Neurology 1994;44:2027-2031.
8. Bompaire F, Mateus C, Taillia H, De Greslan T, Lahutte M, Sallansonnet-Froment M, et al. Severe meningo-radiculo-nevritis associated with ipilimumab. Invest New Drugs 2012;30:2407-2410.
9. Levin KH. L5 radiculopathy with reduced superficial peroneal sensory responses: intraspinal and extraspinal causes. Muscle Nerve 1998;21:3-7.
10. McCluskey L, Feinberg D, Cantor C, Bird S. "Pseudo-conduction block" in vasculitic neuropathy. Muscle Nerve 1999;22:1361-1366.
11. Collins MP, Dyck PJ, Gronseth GS, Guillevin L, Hadden RD, Heuss D, et al. Peripheral Nerve Society Guideline on the classification, diagnosis, investigation, and immunosuppressive therapy of non-systemic vasculitic neuropathy: executive summary. J Peripher Nerv Syst 2010;15:176-184.
12. Pestronk A, Schmidt RE, Choksi RM, Sommerville RB, Al-Lozi MT. Clinical and laboratory features of neuropathies with serum IgM binding to TS-HDS. Muscle Nerve 2012;45:866-872.
13. Sommer C, Koch S, Lammens M, Gabreels-Festen A, Stoll G, Toyka KV. Macrophage clustering as a diagnostic marker in sural nerve biopsies of patients with CIDP. Neurology 2005;65:1924-1929.
14. Midroni G, Bilbao JM, Cohen SM, editors. Biopsy diagnosis of peripheral neuropathy. Woburn, MA: Butterworth Heinemann; 1995. p 185-186.
15. Robinson MR, Chan CC, Yang JC, Rubin BI, Gracia GJ, Sen HN, et al. Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis. J Immunother 2004;27:478-479.
16. Erdem S, Freimer ML, O'Dorisio T, Mendell JR. Procainamide-induced chronic inflammatory demyelinating polyradiculoneuropathy. Neurology 1998;50:824-825.
17. Chaudhry V, Eisenberger MA, Sinibaldi VJ, Sheikh K, Griffin JW, Cornblath DR. A prospective study of suramin-induced peripheral neuropathy. Brain 1996;119:2039-2041.
18. Thaisetthawatkul P, Sundell R, Robertson CE, Dyck PJ. Vasculitic neuropathy associated with minocycline use. J Clin Neuromuscul Dis 2011;12:231-234.
19. Saifee TA, Elliott KJ, Rabin N, Yong KL, D'Sa S, Brandner S, et al. Bortezomib-induced inflammatory neuropathy. J Peripher Nerv Syst 2010;15:366-368.
20. Lachance DH, Lennon VA, Pittock SJ, Tracy JA, Krecke KN, Amrami KK, et al. An outbreak of neurological autoimmunity with polyradiculoneuropathy in workers exposed to aerosolised porcine neural tissue: a descriptive study. Lancet Neurol 2010;9:55-66.
21. Tarhini A, Lo E, Minor DR. Releasing the brake on the immune system: ipilimumab in melanoma and other tumors. Cancer Biother Radiopharm 2010;25:601-613.
22. von Euw E, Chodon T, Attar N, Jalil J, Koya RC, Comin-Anduix B, et al. CTLA4 blockade increases Th17 cells in patients with metastatic melanoma. J Transl Med 2009;7:35.
23. Zhu J, Zou L, Zhu S, Mix E, Shi F, Wang H, et al. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade enhances incidence and severity of experimental autoimmune neuritis in resistant mice. J Neuroimmunol 2001;115:111-117.
24. Leach BC, Kulbersh JS, Day TA, Cook J. Cranial neuropathy as a presenting sign of recurrent aggressive skin cancer. Dermatol Surg 2008;34:483-497.
25. Painter TJ, Chaljub G, Sethi R, Singh H, Gelman B. Intracranial and intraspinal meningeal melanocytosis. AJNR Am J Neuroradiol 2000;21:1349-1353.