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Volumn 170, Issue 1, 2013, Pages 198-201

Leptin promotes human endometrial carcinoma cell proliferation by enhancing aromatase (P450arom) expression and estradiol formation

Author keywords

Endometrial carcinoma; Leptin; Tumor microenvironment

Indexed keywords

ANDROSTENEDIONE; AROMATASE; ESTRADIOL; LEPTIN; MESSENGER RNA;

EID: 84883049179     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2013.04.004     Document Type: Article
Times cited : (24)

References (21)
  • 1
    • 0035995855 scopus 로고    scopus 로고
    • Leptin and body mass index in relation to endometrial cancer risk
    • E. Petridou, M. Belechri, and N. Dessypris Leptin and body mass index in relation to endometrial cancer risk Ann Nutr Metab 46 2002 147 151
    • (2002) Ann Nutr Metab , vol.46 , pp. 147-151
    • Petridou, E.1    Belechri, M.2    Dessypris, N.3
  • 2
    • 0029816596 scopus 로고    scopus 로고
    • Effects of gender, body composition, and menopause on plasma concentrations of leptin
    • M. Rosenbaum, M. Nicolson, and J. Hirsch Effects of gender, body composition, and menopause on plasma concentrations of leptin J Clin Endocrinol Metab 81 1996 3424 3427
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3424-3427
    • Rosenbaum, M.1    Nicolson, M.2    Hirsch, J.3
  • 3
    • 0028873380 scopus 로고
    • Aromatase in human endometrial carcinoma and hyperplasia. Immunohistochemical, in situ hybridization, and biochemical studies
    • K. Watanabe, H. Sasano, and N. Harada Aromatase in human endometrial carcinoma and hyperplasia. Immunohistochemical, in situ hybridization, and biochemical studies Am J Pathol 146 1995 491 500
    • (1995) Am J Pathol , vol.146 , pp. 491-500
    • Watanabe, K.1    Sasano, H.2    Harada, N.3
  • 4
    • 0036846227 scopus 로고    scopus 로고
    • The underlying basis for obesity: Relationship to cancer
    • G.A. Bray The underlying basis for obesity: relationship to cancer J Nutr 132 Suppl. 11 2002 3451S 3455S
    • (2002) J Nutr , vol.132 , Issue.SUPPL. 11
    • Bray, G.A.1
  • 5
    • 18544384373 scopus 로고    scopus 로고
    • Endometrial cancer incidence trends in Europe: Underlying determinants and prospects for prevention
    • F. Bray, I. Dos Santos Silva, H. Moller, and E. Weiderspas Endometrial cancer incidence trends in Europe: underlying determinants and prospects for prevention Cancer Epidemiol Biomarkers Prev 14 2005 1132 1142
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1132-1142
    • Bray, F.1    Dos Santos Silva, I.2    Moller, H.3    Weiderspas, E.4
  • 6
    • 0030434655 scopus 로고    scopus 로고
    • Leptin and OB-R: Body weight regulation by a cytokine receptor
    • D.W. White, and L.A. Tartaglia Leptin and OB-R: body weight regulation by a cytokine receptor Cytokine Growth Factor Rev 7 1996 303 309
    • (1996) Cytokine Growth Factor Rev , vol.7 , pp. 303-309
    • White, D.W.1    Tartaglia, L.A.2
  • 7
    • 0036000280 scopus 로고    scopus 로고
    • Leptin signalling
    • G. Sweeney Leptin signalling Cell Signal 14 2002 655 663
    • (2002) Cell Signal , vol.14 , pp. 655-663
    • Sweeney, G.1
  • 8
    • 58149388704 scopus 로고    scopus 로고
    • Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation
    • S. Catalano, C. Giordano, and P. Rizza Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation J Cell Physiol 218 2009 490 500
    • (2009) J Cell Physiol , vol.218 , pp. 490-500
    • Catalano, S.1    Giordano, C.2    Rizza, P.3
  • 9
    • 37548999022 scopus 로고    scopus 로고
    • Leptin levels in serum depending on body mass index in patients with endometrial hyperplasia and cancer
    • A. Cymbaluk, A. Chudecka-Głaz, and L. Rzepka-Górska Leptin levels in serum depending on body mass index in patients with endometrial hyperplasia and cancer Eur J Obstet Gynecol Reprod Biol 136 2008 74 77
    • (2008) Eur J Obstet Gynecol Reprod Biol , vol.136 , pp. 74-77
    • Cymbaluk, A.1    Chudecka-Głaz, A.2    Rzepka-Górska, L.3
  • 10
    • 62849109985 scopus 로고    scopus 로고
    • Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK and PI3K/AKT pathways in human endometrial cancer cells
    • J. Gao, J. Tian, and Y. Lv Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK and PI3K/AKT pathways in human endometrial cancer cells Cancer Sci 100 2009 389 395
    • (2009) Cancer Sci , vol.100 , pp. 389-395
    • Gao, J.1    Tian, J.2    Lv, Y.3
  • 11
    • 0030956390 scopus 로고    scopus 로고
    • The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line
    • N. Ghilardi, and R.C. Skoda The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line Mol Endocrinol 11 1997 393 399
    • (1997) Mol Endocrinol , vol.11 , pp. 393-399
    • Ghilardi, N.1    Skoda, R.C.2
  • 12
    • 33750576103 scopus 로고    scopus 로고
    • Molecular and pathologic aspects of endometrial carcinogenesis
    • J.L. Hecht, and G.L. Mutter Molecular and pathologic aspects of endometrial carcinogenesis J Clin Oncol 24 2006 4783 4791
    • (2006) J Clin Oncol , vol.24 , pp. 4783-4791
    • Hecht, J.L.1    Mutter, G.L.2
  • 13
    • 0018567779 scopus 로고
    • Estradiol and testosterone levels in the peripheral and ovarian circulations in patients with endometrial cancer
    • J.G. Schenker, D. Weinstein, and E. Okon Estradiol and testosterone levels in the peripheral and ovarian circulations in patients with endometrial cancer Cancer 44 1979 1809 1812
    • (1979) Cancer , vol.44 , pp. 1809-1812
    • Schenker, J.G.1    Weinstein, D.2    Okon, E.3
  • 15
    • 33644891602 scopus 로고    scopus 로고
    • 17Beta-hydroxysteroid dehydrogenases in human endometrium and its disorders
    • K. Ito, H. Utsunomiya, and T. Suzuki 17Beta-hydroxysteroid dehydrogenases in human endometrium and its disorders Mol Cell Endocrinol 248 2006 136 140
    • (2006) Mol Cell Endocrinol , vol.248 , pp. 136-140
    • Ito, K.1    Utsunomiya, H.2    Suzuki, T.3
  • 16
    • 0038792551 scopus 로고    scopus 로고
    • Tumor estrogen content and clinico-morphological and endocrine features of endometrial cancer
    • L.M. Berstein, A.E. Tchernobrovkina, and V.B. Gamajunova Tumor estrogen content and clinico-morphological and endocrine features of endometrial cancer J Cancer Res Clin Oncol 129 2003 245 249
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 245-249
    • Berstein, L.M.1    Tchernobrovkina, A.E.2    Gamajunova, V.B.3
  • 17
    • 0020326596 scopus 로고
    • Significance of aromatase activity in human breast cancer
    • W.R. Miller, R.A. Hawkins, and A.P. Forrest Significance of aromatase activity in human breast cancer Cancer Res 42 Suppl. 8 1982 3365 3368
    • (1982) Cancer Res , vol.42 , Issue.SUPPL. 8 , pp. 3365-3368
    • Miller, W.R.1    Hawkins, R.A.2    Forrest, A.P.3
  • 19
    • 19244378918 scopus 로고    scopus 로고
    • Aromatase (P450AROM) mRNA expression in normal, hyperplastic and malignant endometrium and aromatase activity in endometrial cancer tissue culture
    • R. Tarkowski, M. Skrzypczak, S. Winiarczyk, J. Kotarski, J.A. Jakowicki, and A.J. Jakimiuk Aromatase (P450AROM) mRNA expression in normal, hyperplastic and malignant endometrium and aromatase activity in endometrial cancer tissue culture Ginekol Pol 71 2000 130 135
    • (2000) Ginekol Pol , vol.71 , pp. 130-135
    • Tarkowski, R.1    Skrzypczak, M.2    Winiarczyk, S.3    Kotarski, J.4    Jakowicki, J.A.5    Jakimiuk, A.J.6
  • 20
    • 0020283614 scopus 로고
    • Estrogen synthesis in normal and malignant human endometrium
    • L. Tseng, J. Mazella, W.J. Mann, and J. Chumas Estrogen synthesis in normal and malignant human endometrium J Clin Endocrinol Metab 55 1982 1029 1031
    • (1982) J Clin Endocrinol Metab , vol.55 , pp. 1029-1031
    • Tseng, L.1    Mazella, J.2    Mann, W.J.3    Chumas, J.4
  • 21
    • 0021921969 scopus 로고
    • Aromatization of androstenedione by normal and neoplastic endometrium of the uterus
    • J. Yamaki, T. Yamamoto, and H. Okada Aromatization of androstenedione by normal and neoplastic endometrium of the uterus J Steroid Biochem 22 1985 63 66
    • (1985) J Steroid Biochem , vol.22 , pp. 63-66
    • Yamaki, J.1    Yamamoto, T.2    Okada, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.