The E2F1 oncogene transcriptionally regulates NELL2 in cancer cells

DNA and Cell Biology

Volumn 32, Issue 9, 2013, Pages 517-523

  Kim, Dong Hee ^a   Roh, Yun Gil ^a   Lee, Hyun Hee ^a   Lee, Sang Yeop ^a,b   Kim, Seung Il ^b   Lee, Byung Ju ^c   Leem, Sun Hee ^a  

^a Dong A University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c University of Ulsan   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NELL2 PROTEIN; TRANSCRIPTION FACTOR E2F1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BLADDER CANCER; BREAST CANCER; CANCER CELL; CELL LEVEL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TUMOR INVASION; RETRACTION NOTICE;

BINDING SITES; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONSENSUS SEQUENCE; DISEASE PROGRESSION; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MCF-7 CELLS; NEOPLASM INVASIVENESS; NERVE TISSUE PROTEINS; ONCOGENES; PROMOTER REGIONS, GENETIC; PROTEIN INTERACTION MAPPING; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84883011781     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2013.1974     Document Type: Article

References (24)

1. Aihara, K., Kuroda, S., Kanayama, N., Matsuyama, S., Tanizawa, K., and Horie, M. (2003). A neuron-specific EGF family protein, NELL2, promotes survival of neurons through mitogen- Activated protein kinases. Brain Res Mol Brain Res 116, 86-93 (Pubitemid 36993700)
2. Bai, J., Sata, N., Nagai, H., Wada, T., Yoshida, K., Mano, H., et al. (2004). Genistein-induced changes in gene expression in Panc 1 cells at physiological concentrations of genistein. Pancreas 29, 93-98 (Pubitemid 38971797)
3. Chen, H.Z., Tsai, S.Y., and Leone, G. (2009). Emerging roles of E2Fs in cancer: An exit from cell cycle control. Nat Rev Cancer 9, 785-797
4. Choi, E.J., Kim, D.H., Kim, J.G., Kim, D.Y., Kim, J.D., Seol, O.J., et al. (2010). Estrogen-dependent transcription of the NEL-like 2 (NELL2) gene and its role in protection from cell death. J Biol Chem 285, 25074-25084
5. DeGregori, J., and Johnson, D.G. (2006). Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 6, 739-748 (Pubitemid 44725567)
6. DeGregori, J., Kowalik, T., and Nevins, J.R. (1995). Cellular targets for activation by the E2F1 transcription factor include DNA synthesis-and G1/S-regulatory genes. Mol Cell Biol 15, 4215-4224
7. Iaquinta, P.J., and Lees, J.A. (2007). Life and death decisions by the E2F transcription factors. Curr Opin Cell Biol 19, 649-657 (Pubitemid 350216426)
8. Kim, H., Ha, C.M., Choi, J., Choi, E.J., Jeon, J., Kim, C., et al. (2002). Ontogeny and the possible function of a novel epidermal growth factor-like repeat domain-containing protein, NELL2, in the rat brain. J Neurochem 83, 1389-1400 (Pubitemid 35477478)
9. Kuroda, S., Oyasu, M., Kawakami, M., Kanayama, N., Tanizawa, K., Saito, N., et al. (1999). Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2. Biochem Biophys Res Commun 265, 79-86
10. Lee, J.S., Leem, S.H., Lee, S.Y., Kim, S.C., Park, E.S., Kim, S.B., et al. (2010). Expression signature of E2F1 and its associated genes predict superficial to invasive progression of bladder tumors. J Clin Oncol 28, 2660-2667
11. Li, Y., Shao, J., Shen, K., Xu, Y., Liu, J., and Qian, X. (2012). E2F1- dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells. J Cell Biochem 113, 3165-3177
12. Maeda, K., Matsuhashi, S., Tabuchi, K., Watanabe, T., Katagiri, T., Oyasu, M., et al. (2001). Brain specific human genes, NELL1 and NELL2, are predominantly expressed in neuroblastoma and other embryonal neuroepithelial tumors. Neurol Med Chir (Tokyo) 41, 582-588; discussion 9 (Pubitemid 34062381)
13. Matsuhashi, S., Noji, S., Koyama, E., Myokai, F., Ohuchi, H., Taniguchi, S., et al. (1995). New gene, nel, encoding a M(r) 93 K protein with EGF-like repeats is strongly expressed in neural tissues of early stage chick embryos. Dev Dyn 203, 212-222
14. Matsuyama, S., Aihara, K., Nishino, N., Takeda, S., Tanizawa, K., Kuroda, S., et al. (2004). Enhanced long-term potentiation in vivo in dentate gyrus of NELL2-deficient mice. Neuroreport 15, 417-420 (Pubitemid 38328132)
15. Matsuyama, S., Doe, N., Kurihara, N., Tanizawa, K., Kuroda, S., Iso, H., et al. (2005). Spatial learning of mice lacking a neuronspecific epidermal growth factor family protein, NELL2. J Pharmacol Sci 98, 239-243 (Pubitemid 41296404)
16. Nelson, B.R., Claes, K., Todd, V., Chaverra, M., and Lefcort, F. (2004). NELL2 promotes motor and sensory neuron differentiation and stimulates mitogenesis in DRG in vivo. Dev Biol 270, 322-335 (Pubitemid 38748556)
17. Nelson, B.R., Matsuhashi, S., and Lefcort, F. (2002). Restricted neural epidermal growth factor-like like 2 (NELL2) expression during muscle and neuronal differentiation. Mech Dev 119 Suppl 1, S11-S19 (Pubitemid 39658679)
18. Oyasu, M., Kuroda, S., Nakashita, M., Fujimiya, M., Kikkawa, U., and Saito, N. (2000). Immunocytochemical localization of a neuron-specific thrombospondin-1-like protein, NELL2: Light and electron microscopic studies in the rat brain. Brain Res Mol Brain Res 76, 151-160 (Pubitemid 30133243)
19. Ryu, B.J., Kim, H.R., Jeong, J.K., and Lee, B.J. (2011). Regulation of the female rat estrous cycle by a neural cell-specific epidermal growth factor-like repeat domain containing protein, NELL2. Mol Cells 32, 203-207
20. Tsantoulis, P.K., and Gorgoulis, V.G. (2005). Involvement of E2F transcription factor family in cancer. Eur J Cancer 41, 2403- 2414 (Pubitemid 41540618)
21. Watanabe, T.K., Katagiri, T., Suzuki, M., Shimizu, F., Fujiwara, K., Kanemoto, N., Nakamura, Y., Hirai, Y., Maekawa, H., and Takahashi, E. (1996). Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats, Genomics 38, 273-276 (Pubitemid 27030114)
22. Wu, Z., Zheng, S., and Yu, Q. (2009). The E2F family and the role of E2F1 in apoptosis. Int J Biochem Cell Biol 41, 2389-2397
23. Xu, H.G., Ren, W., Zou, L., Wang, Y., Jin, R., and Zhou, G.P. (2011). Direct repression of the human IRF-3 promoter by E2F1. Immunogenetics 63, 189-196
24. Zou, L., Xu, H.G., Ren, W., Jin, R., Wang, Y., and Zhou, G.P. (2012). Transcriptional activation of the human CD2AP promoter by E2F1. PLoS One 7, e42774