Reliable set-up for in-loop 11C-carboxylations using Grignard reactions for the preparation of [carbonyl-11C]WAY-100635 and [11C]-(+)-PHNO

Applied Radiation and Isotopes

Volumn 82, Issue , 2013, Pages 75-80

  Rami Mark, Christina ^a,b   Ungersboeck, Johanna ^a,b   Haeusler, Daniela ^a,b   Nics, Lukas ^a,b   Philippe, Cecile ^a,b   Mitterhauser, Markus ^a,b   Willeit, Matthaeus ^a   Lanzenberger, Rupert ^a   Karanikas, Georgios ^a   Wadsak, Wolfgang ^a,b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

11C (+) PHNO; carbonyl 11C WAY 100635; Carbon 11; Grignard reaction; Loop method

Indexed keywords

[11C]-(+)-PHNO; [CARBONYL; CARBON-11; GRIGNARD REACTION; LOOP METHOD;

SYNTHESIS (CHEMICAL);

CARBOXYLATION;

N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE CARBONYL C 11; NAXAGOLIDE C 11; TRACER; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CARBOXYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; GRIGNARD REACTION; PRIORITY JOURNAL; RELIABILITY;

EID: 84883008082     PISSN: 09698043     EISSN: 18729800     Source Type: Journal    
DOI: 10.1016/j.apradiso.2013.07.023     Document Type: Article

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