Methods for producing scaffold-free engineered cartilage sheets from auricular and articular chondrocyte cell sources and attachment to porous tantalum

BioResearch Open Access

Volumn 1, Issue 4, 2012, Pages 157-165

  Whitney, G Adam ^a,b,c   Mera, Hisashi ^c   Weidenbecher, Mark ^d   Awadallah, Amad ^b   Mansour, Joseph M ^b,e   Dennis, James E ^a,b,c  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BENAROYA RESEARCH INSTITUTE   (United States)

^d UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^e Case Western Reserve University   (United States)

Author keywords

Biomaterials; Cell culture; Regeneration; Tissue engineering

Indexed keywords

COLLAGEN; GLYCOSAMINOGLYCAN; TANTALUM;

ANIMAL CELL; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL ADHESION; CELL CULTURE; CELL ENGINEERING; CELL EXPANSION; CULTURE MEDIUM; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 84882989656     PISSN: None     EISSN: 21647860     Source Type: Journal    
DOI: 10.1089/biores.2012.0231     Document Type: Article

References (42)

1. Schaefer D, Martin I, Shastri P, et al. In vitro generation of osteochondral composites. Biomaterials. 2000;24:2599-606.
2. Wada Y, Enjo M, Isogai N, et al. Development of bone and cartilage in tissue-engineered human middle phalanx models. Tissue Eng Part A. 2009;12:3765-3778.
3. Lee M, Siu RK, Ting K, et al. Effect of nell-1 delivery on chondrocyte proliferation and cartilaginous extracellular matrix deposition. Tissue Eng Part A. 2010;5:1791-1800.
4. Marlovits S, Tichy B, Truppe M, et al. Chondrogenesis of aged human articular cartilage in a scaffold-free bioreactor. Tissue Eng. 2003;6:1215-1226.
5. Park K, Huang J, Azar F, et al. Scaffold-free, engineered porcine cartilage construct for cartilage defect repair-in vitro and in vivo study. Artif Organs. 2006;8:586-596.
6. Lefebvre V, Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res C Embryo Today. 2005;3:200-212.
7. Mainil-Varlet P, Rieser F, Grogan S, et al. Articular cartilage repair using a tissue-engineered cartilage-like implant: an animal study. Osteoarthr Cartil. 2001;Supplemental A:S6-S15.
8. Jin R, Park S, Choi B, et al. Scaffold-free cartilage fabrication system using passaged porcine chondrocytes and basic fibroblast growth factor. Tissue Eng Part A. 2009;8:1887-1895.
9. Uenaka K, Imai S, Ando K, et al. Relation of low-intensity pulsed ultrasound to the cell density of scaffold-free cartilage in a high-density static semi-open culture system. J Orthop Sci. 2010;6:816-824.
10. StoddartMJ, Ettinger L, Haüselmann HJ. Enhancedmatrix synthesis in de novo, scaffold free cartilage-like tissue subjected to compression and shear. Biotechnol Bioeng. 2006;6:1043-1051.
11. Furukawa KS, Imura K, Tateishi T, et al. Scaffold-free cartilage by rotational culture for tissue engineering. J Biotechnol. 2008;1:134-145.
12. Hoben GM, Athanasiou KA. Creating a spectrum of fibrocartilages through different cell sources and biochemical stimuli. Biotechnol Bioeng. 2008;3:587-598.
13. Brehm W, Aklin B, Yamashita T, et al. Repair of superficial osteochondral defects with an autologous scaffold-free cartilage construct in a caprine model: implantation method and short-term results. Osteoarthr Cartil. 2006;12:1214-1226.
14. Grogan SP, Rieser F, Winkelmann V, et al. A static, closed and scaffold-free bioreactor system that permits chondrogenesis in vitro. Osteoarthr Cartil. 2003;6:403-411.
15. Kitahara S, Nakagawa K, Sah RL, et al. In vivo maturation of scaffold-free engineered articular cartilage on hydroxyapatite. Tissue Eng Part A. 2008;11:1905-1913.
16. Nagai T, Sato M, Furukawa KS, et al. Optimization of allograft implantation using scaffold-free chondrocyte plates. Tissue Eng Part A. 2008;7:1225-1235.
17. Murdoch AD, Grady LM, Ablett MP, et al. Chondrogenic differentiation of human bone marrow stem cells in transwell cultures: generation of scaffold-free cartilage. Stem Cells. 2007;11:2786-2796.
18. Weidenbecher M, Tucker H, Awadallah A, et al. Fabrication of a neotrachea using engineered cartilage. Laryngoscope. 2008;4:593-598.
19. Gilpin DA, Weidenbecher MS, Dennis JE. Scaffold-free tissue-engineered cartilage implants for laryngotracheal reconstruction. Laryngoscope. 2010;3:612-617.
20. Ryan G, Pandit A, Apatsidis D. Fabrication methods of porous metals for use in orthopaedic applications. Biomaterials. 2006;13:2651-2670.
21. Shuler MS, Rooks MD, Roberson JR. Porous tantalum implant in early osteonecrosis of the hip. J Arthroplasty. 2007; 1:26-31.
22. Levine BR, Sporer S, Poggie RA, et al. Experimental and clinical performance of porous tantalum in orthopedic surgery. Biomaterials. 2006;27:4671-4681.
23. Henderson JH, Welter JF, Mansour JM, et al. Cartilage tissue engineering for laryngotracheal reconstruction: comparison of chondrocytes from three anatomic locations in the rabbit. Tissue Eng. 2007;4:843-853.
24. Carrino DA, Arias JL, Caplan AI. A spectrophotometric modification of a sensitive densitometric Safranin O assay for glycosaminoglycans. Biochem Int. 1991;3:485-495.
25. Ham KD, Oegema TR, Loeser RF, et al. Effects of long-term estrogen replacement therapy on articular cartilage IGFBP-2, IGFBP-3, collagen and proteoglycan levels in ovariectomized cynomolgus monkeys. Osteoarthr Cartil. 2004;2: 160-168.
26. Woessner JF. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys. 1961;2:440-447.
27. Kim YJ, Sah RL, Doong JY, et al. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem. 1988;1:168-176.
28. Mak AF, Lai WM, Mow VC. Biphasic indentation of articular cartilage-I. Theoretical analysis. J Biomech. 1987;7:703-714.
29. Mow VC, Gibbs MC, Lai WM, et al. Biphasic indentation of articular cartilage-II. A numerical algorithm and an experimental study. J Biomech. 1989;8-9:853-861.
30. Vunjak-Novakovic G, Martin I, Obradovic B, et al. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res. 1999;1:130-138.
31. Floman Y, Eyre DR, Glimcher MJ. Induction of osteoarthritis in the rabbit knee joint: biochemical studies on the articular cartilage. Clin Orthop. 1980;278-286.
32. Setton LA, Mow VC, Muller FJ, et al. Altered structurefunction relationships for articular cartilage in human osteoarthritis and an experimental canine model. Agents Actions Suppl. 1993;27-48.
33. Sah RL, Yang AS, Chen AC, et al. Physical properties of rabbit articular cartilage after transection of the anterior cruciate ligament. J Orthop Res. 1997;2:197-203.
34. LeRoux MA, Arokoski J, Vail TP, et al. Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy. J Orthop Res. 2000;3: 383-392.
35. Chung C, Erickson IE, Mauck RL, et al. Differential behavior of auricular and articular chondrocytes in hyaluronic acid hydrogels. Tissue Eng Part A. 2008;7:1121-1131.
36. Naumann A, Dennis JE, Awadallah A, et al. Immunochemical and mechanical characterization of cartilage subtypes in rabbit. J Histochem Cytochem. 2002;8:1049-1058.
37. Levine B, Della Valle CJ, Jacobs JJ. Applications of porous tantalum in total hip arthroplasty. J Am Acad Orthop Surg. 2006;12:646-655.
38. Lima EG, Grace Chao P-h, Ateshian GA, et al. The effect of devitalized trabecular bone on the formation of osteochondral tissue-engineered constructs. Biomaterials. 2008;32: 4292-4299.
39. Bal BS, Rahaman MN, Jayabalan P, et al. In vivo outcomes of tissue-engineered osteochondral grafts. J Biomed Mater Res B Appl Biomater. 2010;1:164-174.
40. Ng KW, Lima EG, Bian L, et al. Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model. Tissue Eng Part A. 2010;3: 1041-1051.
41. Ortiz-Monasterio F, Olmedo A, Oscoy LO. The use of cartilage grafts in primary aesthetic rhinoplasty. Plast Reconstr Surg. 1981;5:597-605.
42. Brent B. Auricular repair with autogenous rib cartilage grafts: two decades of experience with 600 cases. Plast Reconstr Surg. 1992;3:355-374.