메뉴 건너뛰기




Volumn 48, Issue 9, 2013, Pages 1055-1065

Diagnostic significance of DOG-1 and PKC-θ expression and c-Kit/PDGFRA mutations in gastrointestinal stromal tumours

Author keywords

C Kit gene; CD117; DOG 1; GISTs; PDGFRA gene; PKC

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BIOLOGICAL MARKER; CD34 ANTIGEN; DESMIN; KI 67 ANTIGEN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN; PROTEIN DOG 1; PROTEIN KINASE C; PROTEIN S 100; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 84882984542     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2013.816770     Document Type: Article
Times cited : (22)

References (41)
  • 1
    • 62849096370 scopus 로고    scopus 로고
    • Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: A randomised, double-blind, placebo-controlled trial
    • Dematteo RP, Ballman KV, Antonescu CR, Maki RG, Pisters PW, Demetri GD, et al. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: A randomised, double-blind, placebo-controlled trial. Lancet 2009;373:1097-104
    • (2009) Lancet , vol.373 , pp. 1097-1104
    • Dematteo, R.P.1    Ballman, K.V.2    Antonescu, C.R.3    Maki, R.G.4    Pisters, P.W.5    Demetri, G.D.6
  • 2
    • 75149163527 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: A review of the literature
    • Laurini JA, Carter JE. Gastrointestinal stromal tumors: A review of the literature. Arch Pathol Lab Med 2010;134: 134-41
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 134-141
    • Laurini, J.A.1    Carter, J.E.2
  • 3
    • 50649085726 scopus 로고    scopus 로고
    • Risk stratification of patients diagnosed with gastrointestinal stromal tumor
    • Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol 2008;39: 1411-19
    • (2008) Hum Pathol , vol.39 , pp. 1411-1419
    • Joensuu, H.1
  • 5
    • 54949099258 scopus 로고    scopus 로고
    • Overexpression of EGFR and absence of C-KIT expression correlate with poor prognosis in salivary gland carcinomas
    • Ettl T, Schwarz S, Kleinsasser N, Hartmann A, Reichert TE, Driemel O. Overexpression of EGFR and absence of C-KIT expression correlate with poor prognosis in salivary gland carcinomas. Histopathology 2008;53:567-77
    • (2008) Histopathology , vol.53 , pp. 567-577
    • Ettl, T.1    Schwarz, S.2    Kleinsasser, N.3    Hartmann, A.4    Reichert, T.E.5    Driemel, O.6
  • 8
    • 77955817308 scopus 로고    scopus 로고
    • DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
    • Novelli M, Rossi S, Rodriguez-Justo M, Taniere P, Seddon B, Toffolatti L, et al. DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours. Histopathology 2010;57:259-70
    • (2010) Histopathology , vol.57 , pp. 259-270
    • Novelli, M.1    Rossi, S.2    Rodriguez-Justo, M.3    Taniere, P.4    Seddon, B.5    Toffolatti, L.6
  • 10
    • 70249090434 scopus 로고    scopus 로고
    • DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: A study of 1840 cases
    • Miettinen M, Wang ZF, Lasota J. DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: A study of 1840 cases. Am J Surg Pathol 2009;33:1401-8
    • (2009) Am J Surg Pathol , vol.33 , pp. 1401-1408
    • Miettinen, M.1    Wang, Z.F.2    Lasota, J.3
  • 12
    • 77951748211 scopus 로고    scopus 로고
    • The utility of discovered on gastrointestinal stromal tumor 1 (DOG1) antibody in surgical pathology-The GIST of it
    • Lee CH, Liang CW, Espinosa I. The utility of discovered on gastrointestinal stromal tumor 1 (DOG1) antibody in surgical pathology-The GIST of it. Adv Anat Pathol 2010;17:222-32
    • (2010) Adv Anat Pathol , vol.17 , pp. 222-232
    • Lee, C.H.1    Liang, C.W.2    Espinosa, I.3
  • 13
    • 80051660391 scopus 로고    scopus 로고
    • DOG1 utility in diagnosing gastrointestinal stromal tumors on fine-needle aspiration
    • Fatima N, Cohen C, Siddiqui MT. DOG1 utility in diagnosing gastrointestinal stromal tumors on fine-needle aspiration. Cancer Cytopathol 2011;119:202-8
    • (2011) Cancer Cytopathol , vol.119 , pp. 202-208
    • Fatima, N.1    Cohen, C.2    Siddiqui, M.T.3
  • 14
    • 79957917277 scopus 로고    scopus 로고
    • DOG1 and PKC-q are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors
    • Kang GH, Srivastava A, Kim YE, Park HJ, Park CK, Sohn TS, et al. DOG1 and PKC-q are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors. Mod Pathol 2011;24:866-75
    • (2011) Mod Pathol , vol.24 , pp. 866-875
    • Kang, G.H.1    Srivastava, A.2    Kim, Y.E.3    Park, H.J.4    Park, C.K.5    Sohn, T.S.6
  • 15
    • 81155160166 scopus 로고    scopus 로고
    • KIT-negative gastrointestinal stromal tumor of the abdominal soft tissue: A clinicopathologic and genetic study of 10 cases
    • Yamamoto H, Kojima A, Nagata S, Tomita Y, Takahashi S, Oda Y. KIT-negative gastrointestinal stromal tumor of the abdominal soft tissue: A clinicopathologic and genetic study of 10 cases. Am J Surg Pathol 2011;35:1287-95
    • (2011) Am J Surg Pathol , vol.35 , pp. 1287-1295
    • Yamamoto, H.1    Kojima, A.2    Nagata, S.3    Tomita, Y.4    Takahashi, S.5    Oda, Y.6
  • 16
    • 77955817308 scopus 로고    scopus 로고
    • DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
    • Novelli M, Rossi S, Rodriguez-Justo M, Taniere P, Seddon B, Toffolatti L, et al. DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours. Histopathology 2010;57:259-70
    • (2010) Histopathology , vol.57 , pp. 259-270
    • Novelli, M.1    Rossi, S.2    Rodriguez-Justo, M.3    Taniere, P.4    Seddon, B.5    Toffolatti, L.6
  • 17
    • 79955947873 scopus 로고    scopus 로고
    • Clinicopathological and immunohistochemical features of gastointestinal stromal tumors
    • Kang YN, Jung HR, Hwang I. Clinicopathological and immunohistochemical features of gastointestinal stromal tumors. Cancer Res Treat 2010;42:135-43
    • (2010) Cancer Res Treat , vol.42 , pp. 135-143
    • Kang, Y.N.1    Jung, H.R.2    Hwang, I.3
  • 19
    • 45549090311 scopus 로고    scopus 로고
    • Characteristics of KIT-negative gastrointestinal stromal tumours and diagnostic utility of protein kinase C theta immunostaining
    • DOI 10.1136/jcp.2007.052225
    • Lee HE, Kim MA, Lee HS, Lee BL, Kim WH. Characteristics of KIT-negative gastrointestinal stromal tumors and diagnostic utility of protein kinase C theta immunostaining. J Clin Pathol 2008;61:722-9 (Pubitemid 351859964)
    • (2008) Journal of Clinical Pathology , vol.61 , Issue.6 , pp. 722-729
    • Lee, H.E.1    Kim, M.A.2    Lee, H.S.3    Lee, B.L.4    Kim, W.H.5
  • 20
    • 84863385776 scopus 로고    scopus 로고
    • Diagnostic relevance of overexpressions of PKC-q and DOG-1 and KIT/PDGFRA gene mutations in extragastrointestinal stromal tumors: A Korean six-centers study of 28 cases
    • Kim KH, Nelson SD, Kim DH, Choi KU, Kim SJ, Min KW, et al. Diagnostic relevance of overexpressions of PKC-q and DOG-1 and KIT/PDGFRA gene mutations in extragastrointestinal stromal tumors: A Korean six-centers study of 28 cases. Anticancer Res 2012;32:923-37
    • (2012) Anticancer Res , vol.32 , pp. 923-937
    • Kim, K.H.1    Nelson, S.D.2    Kim, D.H.3    Choi, K.U.4    Kim, S.J.5    Min, K.W.6
  • 21
    • 69549118533 scopus 로고    scopus 로고
    • PKC-Theta expression in Ewing sarcoma primitive neuroectodermal tumour and malignant peripheral nerve sheath tumour
    • Kang GH, Kim KM, Park CK, Kang DY. PKC-Theta expression in Ewing sarcoma primitive neuroectodermal tumour and malignant peripheral nerve sheath tumour. Histopathology 2009;55:353-69
    • (2009) Histopathology , vol.55 , pp. 353-369
    • Kang, G.H.1    Kim, K.M.2    Park, C.K.3    Kang, D.Y.4
  • 22
    • 77955816314 scopus 로고    scopus 로고
    • Specificity of DOG1 (K9 clone) and protein kinase C theta (clone27)as immunohistochemical markers of gastrointestinal stromal tumour
    • Wong NA, Shelley-Fraser G. Specificity of DOG1 (K9 clone) and protein kinase C theta (clone27)as immunohistochemical markers of gastrointestinal stromal tumour. Histopathology 2010;57:250-8
    • (2010) Histopathology , vol.57 , pp. 250-258
    • Wong, N.A.1    Shelley-Fraser, G.2
  • 23
    • 79957917277 scopus 로고    scopus 로고
    • DOG1 and PKCq are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors
    • Kang GH, Srivastava A, Kim YE, Park HJ, Park CK, Sohn TS, et al. DOG1 and PKCq are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors. Mod Pathol 2011;24:866-75
    • (2011) Mod Pathol , vol.24 , pp. 866-875
    • Kang, G.H.1    Srivastava, A.2    Kim, Y.E.3    Park, H.J.4    Park, C.K.5    Sohn, T.S.6
  • 24
    • 73349131387 scopus 로고    scopus 로고
    • Resistance to tyrosine kinase inhibitors in gasrointestinal stromal tumors
    • Gramza AW, Corless CL, Heinrich MC. Resistance to tyrosine kinase inhibitors in gasrointestinal stromal tumors. Clin Cancer Res 2009;15:7510-18
    • (2009) Clin Cancer Res , vol.15 , pp. 7510-7518
    • Gramza, A.W.1    Corless, C.L.2    Heinrich, M.C.3
  • 25
    • 11144284051 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up
    • DOI 10.1097/01.pas.0000146010.92933.de
    • Miettinen M, Sobin LH, Lasota J. Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical and molecular genetic study of 1765 cases with long-Term follow-up. Am J Surg Pathol 2005;29:52-68 (Pubitemid 40023952)
    • (2005) American Journal of Surgical Pathology , vol.29 , Issue.1 , pp. 52-68
    • Miettinen, M.1    Sobin, L.H.2    Lasota, J.3
  • 28
    • 84869226674 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: A review of case reports, diagnosis, treatment, and future directions
    • Tan CB, Zhi W, Shahzad G, Mustacchia P. Gastrointestinal stromal tumors: A review of case reports, diagnosis, treatment, and future directions. ISRN Gastroenterol 2012;2012: 595968
    • (2012) ISRN Gastroenterol , vol.2012 , pp. 595968
    • Tan, C.B.1    Zhi, W.2    Shahzad, G.3    Mustacchia, P.4
  • 29
    • 24944536236 scopus 로고    scopus 로고
    • Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: A study by the Spanish Group for Sarcoma Research (GEIS
    • Martín J, Poveda A, Llombart-Bosch A, Ramos R, López-Guerrero JA, García del Muro J, et al. Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: A study by the Spanish Group for Sarcoma Research (GEIS). J Clin Oncol 2005;23:6190-8
    • (2005) J Clin Oncol , vol.23 , pp. 6190-6198
    • Martín, J.1    Poveda, A.2    Llombart-Bosch, A.3    Ramos, R.4    López-Guerrero, J.A.5    García Del Muro, J.6
  • 30
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis, and differential diagnosis
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors: Review on morphology, m olecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med 2006;130: 1466-78 (Pubitemid 44520713)
    • (2006) Archives of Pathology and Laboratory Medicine , vol.130 , Issue.10 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 33
    • 49749122255 scopus 로고    scopus 로고
    • Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours
    • Lasota J, Miettinen M. Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. Histopathology 2008;53:245-66
    • (2008) Histopathology , vol.53 , pp. 245-266
    • Lasota, J.1    Miettinen, M.2
  • 34
    • 33750618188 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Pathology and prognosis at different sites
    • DOI 10.1053/j.semdp.2006.09.001, PII S0740257006001432
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors: Pathology and prognosis at different sites. Semin Diagn Pathol 2006;23:70-83 (Pubitemid 44692418)
    • (2006) Seminars in Diagnostic Pathology , vol.23 , Issue.2 , pp. 70-83
    • Miettinen, M.1    Lasota, J.2
  • 35
    • 69549118533 scopus 로고    scopus 로고
    • PKC-Theta expression in Ewing sarcoma/primitive neuroectodermal tumour and malignant peripheral nerve sheath tumor
    • Kang GH, Kim KM, Park CK, Kang DY. PKC-Theta expression in Ewing sarcoma/primitive neuroectodermal tumour and malignant peripheral nerve sheath tumor. Histopathology 2009;55:368-9
    • (2009) Histopathology , vol.55 , pp. 368-369
    • Kang, G.H.1    Kim, K.M.2    Park, C.K.3    Kang, D.Y.4
  • 36
    • 84856354552 scopus 로고    scopus 로고
    • Polish Clinical GIST Registry.Prognostic value of KIT/PDGFRA mutations in gastrointestinal stromal tumours (GIST): Polish Clinical GIST Registry experience
    • Wozniak A, Rutkowski P, Piskorz A, Ciwoniuk M, Osuch C, Bylina E, et al. Polish Clinical GIST Registry.Prognostic value of KIT/PDGFRA mutations in gastrointestinal stromal tumours (GIST): Polish Clinical GIST Registry experience. Ann Oncol 2012;23:353-60
    • (2012) Ann Oncol , vol.23 , pp. 353-360
    • Wozniak, A.1    Rutkowski, P.2    Piskorz, A.3    Ciwoniuk, M.4    Osuch, C.5    Bylina, E.6
  • 37
    • 79953125715 scopus 로고    scopus 로고
    • Gene mutations and prognostic factors analysis in extragastrointestinal stromal tumor of a chinese three-center study
    • Zheng S, Huang KE, Tao DY, Pan YL. Gene mutations and prognostic factors analysis in extragastrointestinal stromal tumor of a chinese three-center study. J Gastrointest Surg 2011;15:675-81
    • (2011) J Gastrointest Surg , vol.15 , pp. 675-681
    • Zheng, S.1    Huang, K.E.2    Tao, D.Y.3    Pan, Y.L.4
  • 38
    • 14344256167 scopus 로고    scopus 로고
    • PDGFRα- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features
    • DOI 10.1111/j.1365-2559.2005.02061.x
    • Pauls K, Merkelbach-Bruse S, Thal D, Buttner R, Wardelmann E. PDGFR-A and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features. Histopathology 2005;46:166-75 (Pubitemid 40293015)
    • (2005) Histopathology , vol.46 , Issue.2 , pp. 166-175
    • Pauls, K.1    Merkelbach-Bruse, S.2    Thal, D.3    Buttner, R.4    Wardelmann, E.5
  • 39
    • 0041971080 scopus 로고    scopus 로고
    • Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors
    • DOI 10.1016/S0016-5085(03)01046-1
    • Hirota S, Ohashi A, Nishida T, Isozaki K, Kinoshita K, Shinomura Y, et al. Gain-of-function mutations of platelet-derived growth factor receptora gene in gastrointestinal stromal tumors. Gastroenterology 2003;125:660-7 (Pubitemid 37070684)
    • (2003) Gastroenterology , vol.125 , Issue.3 , pp. 660-667
    • Hirota, S.1    Ohashi, A.2    Nishida, T.3    Isozaki, K.4    Kinoshita, K.5    Shinomura, Y.6    Kitamura, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.