Dynamic hydraulic fluid stimulation regulated intramedullary pressure

Bone

Volumn 57, Issue 1, 2013, Pages 137-141

  Hu, Minyi ^a   Serra Hsu, Frederick ^a   Bethel, Neville ^a   Lin, Liangjun ^a   Ferreri, Suzanne ^a   Cheng, Jiqi ^a   Qin, Yi Xian ^a  

^a St Francis Hospital The Heart Center   (United States)

Author keywords

Bone fluid flow; Bone remodeling; Hydraulic fluid stimulation; Intramedullary pressure; Loading rate; Mechanical loading

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BONE STRESS; CONTROLLED STUDY; DYNAMIC HYDRAULIC STIMULATION; FEMALE; FEMUR; FLUID FLOW; INTRAMEDULLARY PRESSURE; MECHANICAL STRESS; NON INVASIVE PROCEDURE; NONHUMAN; OSCILLATION; PRESSURE; RAT; TIBIA;

BONE FLUID FLOW; BONE REMODELING; HYDRAULIC FLUID STIMULATION; INTRAMEDULLARY PRESSURE; LOADING RATE; MECHANICAL LOADING;

ANIMALS; BONE DISEASES, METABOLIC; BONE REMODELING; FEMALE; MECHANOTRANSDUCTION, CELLULAR; MUSCLE, SKELETAL; OSTEOPOROSIS; RATS; RATS, SPRAGUE-DAWLEY; STRESS, MECHANICAL;

EID: 84882965210     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.07.030     Document Type: Article

References (39)

1. Lau R.Y., Guo X. A review on current osteoporosis research: with special focus on disuse bone loss. J Osteoporos 2011, 2011:293808.
2. Pedersen E.A., Akhter M.P., Cullen D.M., Kimmel D.B., Recker R.R. Bone response to in vivo mechanical loading in C3H/HeJ mice. Calcif Tissue Int 1999, 65:41-46.
3. Kameyama Y., Hagino H., Okano T., Enokida M., Fukata S., Teshima R. Bone response to mechanical loading in adult rats with collagen-induced arthritis. Bone 2004, 35:948-956.
4. Hsieh Y.F., Robling A.G., Ambrosius W.T., Burr D.B., Turner C.H. Mechanical loading of diaphyseal bone in vivo: the strain threshold for an osteogenic response varies with location. J Bone Miner Res 2001, 16:2291-2297.
5. Xie L., Rubin C., Judex S. Enhancement of the adolescent murine musculoskeletal system using low-level mechanical vibrations. J Appl Physiol 2008, 104:1056-1062.
6. Tanaka S.M., Sun H.B., Yokota H. Bone formation induced by a novel form of mechanical loading on joint tissue. Biol Sci Space 2004, 18:41-44.
7. Yokota H., Tanaka S.M. Osteogenic potentials with joint-loading modality. J Bone Miner Metab 2005, 23:302-308.
8. Zhang P., Tanaka S.M., Sun Q., Turner C.H., Yokota H. Frequency-dependent enhancement of bone formation in murine tibiae and femora with knee loading. J Bone Miner Metab 2007, 25:383-391.
9. Lam H., Qin Y.X. The effects of frequency-dependent dynamic muscle stimulation on inhibition of trabecular bone loss in a disuse model. Bone 2008, 43:1093-1100.
10. Ozcivici E., Luu Y.K., Adler B., Qin Y.X., Rubin J., Judex S., et al. Mechanical signals as anabolic agents in bone. Nat Rev Rheumatol 2010, 6:50-59.
11. Pollack S.R., Korostoff E., Sternberg M.E., Koh J. Stress-generated potentials in bone: effects of collagen modifications. J Biomed Mater Res 1977, 11:677-70.
12. Montgomery R.J., Sutker B.D., Bronk J.T., Smith S.R., Kelly P.J. Interstitial fluid flow in cortical bone. Microvasc Res 1988, 35:295-307.
13. Reich K.M., Gay C.V., Frangos J.A. Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production. J Cell Physiol 1990, 143:100-104.
14. Rubin J., Biskobing D., Fan X., Rubin C., McLeod K., Taylor W.R. Pressure regulates osteoclast formation and MCSF expression in marrow culture. J Cell Physiol 1997, 170:81-87.
15. Jacobs C.R., Yellowley C.E., Davis B.R., Zhou Z., Cimbala J.M., Donahue H.J. Differential effect of steady versus oscillating flow on bone cells. J Biomech 1998, 31:969-976.
16. Burger E.H., Klein-Nulend J. Mechanotransduction in bone-role of the lacuno-canalicular network. FASEB J 1999, 13:S101-S112. [Suppl.].
17. Rubin C.T., Sommerfeldt D.W., Judex S., Qin Y. Inhibition of osteopenia by low magnitude, high-frequency mechanical stimuli. Drug Discov Today 2001, 6:848-858.
18. Qin Y.X., Kaplan T., Saldanha A., Rubin C. Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity. J Biomech 2003, 36:1427-1437.
19. Winet H. A bone fluid flow hypothesis for muscle pump-driven capillary filtration: II. Proposed role for exercise in erodible scaffold implant incorporation. Eur Cell Mater 2003, 6:1-10. [discussion 10-1].
20. Otter M.W., Qin Y.X., Rubin C.T., McLeod K.J. Does bone perfusion/reperfusion initiate bone remodeling and the stress fracture syndrome?. Med Hypotheses 1999, 53:363-368.
21. Kwon R.Y., Meays D.R., Tang W.J., Frangos J.A. Microfluidic enhancement of intramedullary pressure increases interstitial fluid flow and inhibits bone loss in hindlimb suspended mice. J Bone Miner Res 2010, 25:1798-1807.
22. Qin Y.X., Lam H. Intramedullary pressure and matrix strain induced by oscillatory skeletal muscle stimulation and its potential in adaptation. J Biomech 2009, 42:140-145.
23. Lam H., Hu M., Qin Y.X. Alteration of contraction-to-rest ratio to optimize trabecular bone adaptation induced by dynamic muscle stimulation. Bone 2011, 48:399-405.
24. Lam H., Brink P., Qin Y.X. Skeletal nutrient vascular adaptation induced by external oscillatory intramedullary fluid pressure intervention. J Orthop Surg Res 2010, 5:18.
25. Hu M., Cheng J., Qin Y.X. Dynamic hydraulic flow stimulation on mitigation of trabecular bone loss in a rat functional disuse model. Bone 2012, 51:819-825.
26. Turner C.H., Owan I., Takano Y. Mechanotransduction in bone: role of strain rate. Am J Physiol 1995, 269:E438-E442.
27. Hsieh Y.F., Turner C.H. Effects of loading frequency on mechanically induced bone formation. J Bone Miner Res 2001, 16:918-924.
28. Rubin C.T., McLeod K.J. Promotion of bony ingrowth by frequency-specific, low-amplitude mechanical strain. Clin Orthop Relat Res 1994, 165-174.
29. Warden S.J., Turner C.H. Mechanotransduction in the cortical bone is most efficient at loading frequencies of 5-10Hz. Bone 2004, 34:261-270.
30. Wang L., Fritton S.P., Weinbaum S., Cowin S.C. On bone adaptation due to venous stasis. J Biomech 2003, 36:1439-1451.
31. Wang L., Ciani C., Doty S.B., Fritton S.P. Delineating bone's interstitial fluid pathway in vivo. Bone 2004, 34:499-509.
32. Stevens H.Y., Meays D.R., Frangos J.A. Pressure gradients and transport in the murine femur upon hindlimb suspension. Bone 2006, 39:565-572.
33. Valic Z., Buckwalter J.B., Clifford P.S. Muscle blood flow response to contraction: influence of venous pressure. J Appl Physiol 2005, 98:72-76.
34. Laughlin M.H. The muscle pump: what question do we want to answer?. J Appl Physiol 2005, 99:774.
35. Qin Y.X., Lam H., Ferreri S., Rubin C. Dynamic skeletal muscle stimulation and its potential in bone adaptation. J Musculoskelet Neuronal Interact 2010, 10:12-24.
36. Hu M., Yeh R., Lien M., Teeratananon M., Agarwal K., Qin Y.X. Dynamic fluid flow mechanical stimulation modulates bone marrow mesenchymal stem cells. Bone Res 2013, 98-104.
37. Zhang S., Cheng J., Qin Y.X. Mechanobiological modulation of cytoskeleton and calcium influx in osteoblastic cells by short-term focused acoustic radiation force. PLoS One 2012, 7:e38343.
38. Knothe Tate M.L., Steck R., Forwood M.R., Niederer P. In vivo demonstration of load-induced fluid flow in the rat tibia and its potential implications for processes associated with functional adaptation. J Exp Biol 2000, 203:2737-2745.
39. Azar T., Sharp J., Lawson D. Heart rates of male and female Sprague-Dawley and spontaneously hypertensive rats housed singly or in groups. J Am Assoc Lab Anim Sci 2011, 50(2):175-184.