Development and validation of a 96-well cellular assay for the discovery of ALDH1A1 inhibitors

Assay and Drug Development Technologies

Volumn 11, Issue 6, 2013, Pages 388-395

  Ming, Wenyu ^a   Ma, Wenzhen ^a   Chen, Lisa H ^a   Volk, Catherine ^a   Michael, Mervyn Dodson ^a   Xu, Yanping ^a   Zhang, Fang ^a   Wang, Xiaojun ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE INHIBITOR; GLUTAMINE; RETINOIC ACID;

ALCOHOL OXIDATION; ARTICLE; CELL ASSAY; CELL COUNT; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYMATIC ASSAY; ENZYME ACTIVITY; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE IMAGING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALDEHYDE DEHYDROGENASE; BORON COMPOUNDS; DRUG DISCOVERY; ENZYME INHIBITORS; HEP G2 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; REAGENT KITS, DIAGNOSTIC;

EID: 84882958621     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2013.513     Document Type: Article

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