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Volumn 987, Issue , 2013, Pages 71-77

Identification of endogenous substrates of orphan cytochrome P450 enzymes through the use of untargeted metabolomics approaches

Author keywords

Cytochrome P450; HPLC MS; Metabolomics; Orphan enzyme

Indexed keywords

CYTOCHROME P450; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; GLUCOSE 6 PHOSPHATE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE;

EID: 84882931268     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-321-3_6     Document Type: Article
Times cited : (6)

References (7)
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    • Guengerich FP et al (2011) Approaches to deorphanization of human and microbial cytochrome P450 enzymes. Biochim Biophys Acta 1814:139-145
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    • Guengerich, F.P.1
  • 2
    • 79960657926 scopus 로고    scopus 로고
    • Orphans in the human cytochrome p450 superfamily: Approaches to discovering functions and relevance in pharmacology
    • Guengerich FP, Cheng Q (2011) Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology. Pharmacol Rev 63: 684-699
    • (2011) Pharmacol Rev , vol.63 , pp. 684-699
    • Guengerich, F.P.1    Cheng, Q.2
  • 3
    • 77953512029 scopus 로고    scopus 로고
    • Characterizing proteins of unknown function: Orphan cytochrome p450 enzymes as a paradigm
    • Guengerich FP et al (2010) Characterizing proteins of unknown function: orphan cytochrome P450 enzymes as a paradigm. Mol Interv 10:153-163
    • (2010) Mol Interv , vol.10 , pp. 153-163
    • Guengerich, F.P.1
  • 4
    • 77952498181 scopus 로고    scopus 로고
    • Signature-discovery approach for sample matching of a nerve-agent precursor using liquid chromatography-mass spectrometry, xcms, and chemometrics
    • Fraga CG et al (2010) Signature-discovery approach for sample matching of a nerve-agent precursor using liquid chromatography-mass spectrometry, XCMS, and chemometrics. Anal Chem 82:4165-4173
    • (2010) Anal Chem , vol.82 , pp. 4165-4173
    • Fraga, C.G.1
  • 5
    • 32444446805 scopus 로고    scopus 로고
    • Xcms: Processing mass spectrometry data for metabolite pro filing using nonlinear peak alignment, matching, and identi fication
    • Smith CA et al (2006) XCMS: processing mass spectrometry data for metabolite pro filing using nonlinear peak alignment, matching, and identi fication. Anal Chem 78:779-787
    • (2006) Anal Chem , vol.78 , pp. 779-787
    • Smith, C.A.1
  • 6
    • 78049407027 scopus 로고    scopus 로고
    • Cyclization of a cellular dipentaenone by streptomyces coelicolor cytochrome p450 154a1 without oxidation/reduction
    • Cheng Q et al (2010) Cyclization of a cellular dipentaenone by Streptomyces coelicolor cytochrome P450 154A1 without oxidation/reduction. J Am Chem Soc 132:15173-15175
    • (2010) J Am Chem Soc , vol.132 , pp. 15173-15175
    • Cheng, Q.1
  • 7
    • 0031822496 scopus 로고    scopus 로고
    • Role of the alanine at position 363 of cytochrome p450 2b2 in in fluencing the nadph-and hydroperoxide-supported activities
    • Hanna IH et al (1998) Role of the alanine at position 363 of cytochrome P450 2B2 in in fluencing the NADPH-and hydroperoxide-supported activities. Arch Biochem Biophys 350:324-332
    • (1998) Arch Biochem Biophys , vol.350 , pp. 324-332
    • Hanna, I.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.