Mechanisms of Spinal Cord Stimulation in Neuropathic and Ischemic Pain Syndromes

Neuromodulation

Volumn 1, Issue , 2009, Pages 345-354

  Linderoth, Bengt ^a,b   Foreman, Robert D ^b   Meyerson, Björn A ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882905276     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374248-3.00026-4     Document Type: Chapter

References (81)

1. M. Ather, P. Di Vadi, D. Light, J.R. Wedley and W.C. Hamann (2003) Spinal cord stimulation does not change peripheral skin blood flow in patients with neuropathic pain. Eur. J. Anaesthesiol. 20 736-739.
2. G. Barolat, J.C. Oakley, J.D. Law, R.B. North, R.N. Ketcik and A. Sharan (2001) Epidural spinal cord stimulation with a multiple electrode paddle lead is effective in treating intractable low back pain. Neuromodulation 4 59-66.
3. R. Baron (2004) Can we model CRPS type 1? Pain 11 8-9.
4. R. Baron, J.D. Levine and H.L. Fields (1999) Causalgia and reflex sympathetic dystrophy: does the sympathetic nervous system contribute to the generation of pain? Muscle Nerve 22 678-695.
5. G.J. Bennett and Y.K.A. Xie (1988) Peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33 87-107.
6. Brumovsky, P.R. (2005) Neuropeptides, sensory neurons and pain modulation. Doctoral thesis. Karolinska Institutet, Stockholm. 80 pp.
7. M.J. Chandler, T.J. Brennan, D.W. Garrison, K.S. Kim, P.J. Schwartz and R.D. Foreman (1993) A mechanism of cardiac pain suppression by spinal cord stimulation: implications for patients with angina pectoris. Eur. Heart J. 14 96-105.
8. T.J. Coderre, D.N. Xanthos, L. Francis and G.J. Bennett (2004) Chronic post-ischemia pain (CPIP): a novel animal model of complex regional pain syndrome-type I (CRPS-I; reflex sympathetic dystrophy) produced by prolonged hindpaw ischemia and reperfusion in the rat. Pain 112 94-105.
9. J.E. Croom, R.D. Foreman, M.J. Chandler and K.W. Barron (1997) Cutaneous vasodilation during dorsal column stimulation is mediated by dorsal roots and CGRP. Am. J. Physiol. Heart Circ. Physiol. 272 H950-H957.
10. J.E. Croom, R.D. Foreman, M.J. Chandler and K.W. Barron (1998) Reevaluation of the role of the sympathetic nervous system in cutaneous vasodilation during dorsal spinal cord stimulation: are multiple mechanisms active? Neuromodulation 1 91-101.
11. J.G. Cui, B. Linderoth and B.A. Meyerson (1996) Effects of spinal cord stimulation on touch-evoked allodynia involve GABAergic mechanisms. An experimental study in the mononeuropathic rat. Pain 66 287-295.
12. J.G. Cui, W.T. O’Connor, U. Ungerstedt, B.A. Meyerson and B. Linderoth (1997) Spinal cord stimulation attenuates augmented dorsal horn release of excitatory amino acids in mononeuropathy via a GABAergic Mechanism. Pain 73 87-95.
13. J.G. Cui, A. Sollevi, B. Linderoth and B.A. Meyerson (1997) Adenosine receptor activation suppresses tactile hypersensitivity and potentiates effect of spinal cord in mononeuropathic rats. Neurosci Lett. 223 173-176.
14. I. Decosterd and C.J. Woolf (2000) Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 87 149-158.
15. S. Eddicks, K. Maier-Hauff, M. Schenk, A. Muller, G. Baumann and H. Theres (2007) Thoracic spinal cord stimulation improves functional status and relieves symptoms in patients with refractory angina pectoris: the first placebo-controlled randomised study. Heart 93 585-590.
16. C. El-Khoury, N. Hawwa, M. Baliki, S.F. Atweh, S.J. Jabbur and N.E. Saadé (2002) Attenuation of neuropathic pain by segmental and suprasinal activation of the dorsal column system in awake rats. Neuroscience 112 541-553.
17. H.K.P. Feirabend, S. Choufoer, S. Ploeger, J. Holsheimer and J.D. van Gool (2002) Morphometry of human superficial dorsal and dorsolateral column fibres: significance to cord stimulation. Brain 125 1137-1149.
18. R.D. Foreman, J.E. Beall, A.E. Applebaum, J.D. Coulter and W.D. Willis (1976) Effects of dorsal column stimulation on primate spinothalamic tract neurons. J. Neurophysiol. 39 534-546.
19. L. Garcia-Larrea, M. Sindou and F. Mauguière (1989) Nociceptive flexion reflexes during analgesic neurostimulation in man. Pain 39 145-156.
20. B. Gazelius, J.G. Cui, M. Svensson, B. Meyerson and B. Linderoth (1996) Photochemically induced ischaemic lesion of the rat sciatic nerve. A novel method providing high incidence of mononeuropathy. Neuroreport 7 2619-2623.
21. G. Gherardini, T. Lundeberg, J. Cui, S.V. Eriksson, S. Trubek and B. Linderoth (1999) Spinal cord stimulation improves survival in ischemic skin flaps: an experimental study of the possible mediation by calcitonin gene-related peptide. Plast. Reconstr. Surg. 103 1221-1228.
22. T.Z. Guo, T. Wei and W.S. Kingery (2006) Glucocorticoid inhibition of vascular abnormalities in a tibia fracture rat model of complex regional pain syndrome type I. Pain 121 158-167.
23. P. Hansson (2003) Difficulties in stratifying neuropathic pain by mechanisms. Eur. J. Pain 7 353-357.
24. H. Harke, P. Gretenkort, H.U. Ladleif and S. Rahman (2005) Spinal cord stimulation in sympathetically maintained complex regional pain syndrome type I with severe disability. A prospective clinical study. Eur. J. Pain 9 363-373.
25. J. Holsheimer (1998) Computer modelling of spinal cord stimulation and its contribution to therapeutic efficacy. Spinal Cord 36 531-540.
26. T. Hökfelt, X. Zhang and Z. Wiesenfeld-Hallin (1994) Messenger plasticity in primary sensory neurons following axotomy and its functional implications. TINS 17 22-30.
27. R.R. Ji, Q. Zhang, K. Bedecs, J. Arvidsson, X. Zhang, Z. Wiesenfeld-Hallin, T. Bartfai and T. Hökfelt (1994) Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy. Proc. Natl Acad. Sci. U S A 91 12540-12543.
28. M.A. Kemler, G.A. Barendse, M. van Kleef, H.C. de Vet, C.P. Rijks, C.A. Furnee and F.A. van den Wildenberg (2000) Spinal cord stimulation in patients with chronic reflex sympathetic dystrophy. N. Engl. J. Med. 343 618-624.
29. M.A. Kemler, G.A. Barendse, M. van Kleef and M.G. Egbrink (2000) Pain relief in complex regional pain syndrome due to spinal cord stimulation does not depend on vasodilation. Anesthesiology 92 1653-1660.
30. S.H. Kim and J.M. Chung (1992) An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50 355-363.
31. K. Kumar, R.K. Nath and C. Toth (1997) Spinal cord stimulation is effective in the management of reflex sympathetic dystrophy. Neurosurgery 40 503-508.
32. G. Lind, B.A. Meyerson, J. Winter and B. Linderoth (2004) Intrathecal baclofen as adjuvant therapy to enhance the effect of spinal cord stimulation in neuropathic pain: a pilot study. Eur. J. Pain 8 377-383.
33. G. Lind, G. Schechtmann, J., Winter and B.A. Meyerson (2008) Baclofen-enhanced spinal cord stimulation and intrathecal balofen alone for neuropathic pain: long- term outcome of a pilot study. Eur. J. Pain, 12 132-136.
34. U. Lindblom and B.A. Meyerson (1975) Influences on touch, vibration and cutaneous pain of dorsal column stimulation in man. Pain 1 257-270.
35. U. Lindblom and B.A. Meyerson (1976) Mechanoreceptive and nociceptive thresholds during dorsal column stimulation in man. J. Bonica, D. Albe-Fessard (Eds) Advances in Pain Research and Therapy Vol. 1 New York: Raven Press 469-474.
36. B. Linderoth (1995) Spinal cord stimulation in ischemia and ischemic pain. S. Horsch, L. Claeys (Eds) Spinal Cord Stimulation: An Innovative Method in the Treatment of PVD and Angina Darmstdt: Steinkopff Verlag 19-35.
37. B. Linderoth and R.D. Foreman (1999) Physiology of spinal cord stimulation. Review and Update. Neuromodulation 2 150-164.
38. B. Linderoth and R.D. Foreman (2006) Mechanisms of spinal cord stimulation in painful syndromes. Role of animal models. Pain Med. 7(Suppl. 1), 14-26.
39. B. Linderoth and B.A. Meyerson (1995) Dorsal column stimulation: modulation of somatosensory and autonomic function. S.B. McMahon, P.D. Wall (Eds) The Neurobiology of Pain. Seminars in the Neurosciences Vol. 7 London: Academic Press 263-277.
40. B. Linderoth and B.A. Meyerson (2001) Central nervous system stimulation for neuropathic pain. P. Hansson, R.G. Hill, H.L. Fields, P. Marchettini (Eds) Neuropathic Pain: Pathophysiology and Treatment. Progress in Pain Research and Management Vol. 21 Seattle, WA: IASP Press 223-249.
41. B. Linderoth, B. Gazelius, J. Franck and E. Brodin (1992) Dorsal column stimulation induces release of serotonin and substance P in the cat dorsal horn. Neurosurgery 31 289-297.
42. B. Linderoth, G. Gheradini, B. Ren and T. Lundeberg (1995) Pre-emptive spinal cord stimulation reduces ischemia in an animal model of vasospasm. Neurosurgery 37 266-272.
43. B. Linderoth, L. Gunasekera and B.A. Meyerson (1991) Effects of sympathectomy on skin and muscle microcirculation during dorsal column stimulation: animal studies. Neurosurgery 29 874-879.
44. B. Linderoth, P. Herregodts and B.A. Meyerson (1994) Sympathetic mediation of peripheral vasodilation induced by spinal cord stimulation: animal studies of the role of cholinergic and adrenergic receptor subtypes. Neurosurgery 35 711-719.
45. M.B. Max and I. Gilron (1999) Sympathetically maintained pain: has the emperor no clothes? Neurology 52 905-907.
46. J. Mao (2002) Translational pain research: bridging the gap between basic and clinical research. Pain 97 183-187.
47. B.A. Meyerson and B. Linderoth (2003) Spinal cord stimulation: mechanisms of action in neuropathic and ischemic pain. B.A. Simpson (Eds) Electrical Stimulation and the Relief of Pain New York: Elsevier 161-182.
48. B.A. Meyerson and B. Linderoth (2006) Mode of action of spinal cord stimulation in neuropathic pain. J. Pain Symptom Manag. 31(4 Suppl.), S6-S12.
49. B.A. Meyerson, E. Brodin and B. Linderoth (1985) Possible neurohumoral mechanisms in CNS stimulation for pain suppression. Appl. Neurophysiol. 48 175-180.
50. B.A. Meyerson, B. Ren, P. Herregodts and B. Linderoth (1995) Spinal cord stimulation in animal models of mononeuropathy: effects on the withdrawal response and the flexor reflex. Pain 61 229-243.
51. Michaelis (2000) Coupling of sympathetic and somatosensory neurons following nerve injury: mechanisms and potential significance for the generation of pain. M. Devor, M.C. Rowbotham, Z. Wiesenfeld,(Eds) Progress in Pain Research and Management IASP: Seattle, WA: 645-656. (Proceedings 9th World Congress on Pain) Vol. 16
52. B.S. Nashold (1977) Overview of neuroaugmentation. Neurosurgery 1 230-232.
53. B.S. Nashold, G. Somjen and H. Friedman (1972) Paresthesias and EEG potentials evoked by stimulation of the dorsal funiculi in man. Exp. Neurol. 36 273-287.
54. R.B. North, D.H. Kidd, M. Zahurak, C.S. James and D.M. Long (1993) Spinal cord stimulation for chronic, intractable pain: experience over two decades. Neurosurgery 32 384-395.
55. R.B. North, D.H. Kidd, J. Olin, J.M. Sieracki, F. Farrokhi, L. Petrucci and P.N. Cutchis (2005) Spinal cord stimulation for axial low back pain: a prospective, controlled trial comparing dual with single percutaneous electrodes. Spine 30 1412-1418.
56. H. Obata, X. Li and J.C. Eisenach (2005) Alpha2-adrenoceptor activation by clonidine enhances stimulation-evoked acetylcholine release from spinal cord tissue after nerve ligation in rats. Anesthesiology 102 657-662.
57. H. Obata, S. Saito, M. Sasaki and F. Goto (2002) Possible involvement of a muscarinic receptor in the anti-allodynic action of a 5-HT2 receptor agonist in rats with nerve ligation injury. Brain Res. 932 124-128.
58. D.D. Ohnmeiss and R.F. Rashbaum (2001) Patient satisfaction with spinal cord stimulation for predominant complaints of chronic, intractable low back pain. The Spine J. 1 358-363.
59. G.L. Olsson, B.A. Meyerson and B. Linderoth (2008) Spinal cord stimulation in adolescents with Complex Regional Pain Syndrome type I (CARPS-I). Eur. J. Pain 12 53-59.
60. N.E. Saadé and S.J. Jabbur (2008) Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms. Prog. Neurobiol. 86 22-47.
61. N.E. Saadé, H. Al Amin, S. Chalouhi, S.A. Baki, S.J. Jabbur and S.F. Atweh (2006) Spinal pathways involved in supraspinal modulation of neuropathic manifestations in rats. Pain 12 280-293.
62. N.E. Saadé, M.S. Tabet, S.A. Soueidan, M. Bitar, S.F. Atweh and S.J. Jabbur (1986) Supraspinal modulation of noceception in awake rats by stimulation of the dorsal column nuclei. Brain Res. 369 307-310.
63. G. Schechtmann, Z. Song, C. Ultenius, B.A. Meyerson and B. Linderoth (2008) Cholinergic mechanisms involved in the pain relieving effect of spinal cord stimulation in a model of neuropathy. Pain 139 136-145.
64. G. Schechtmann, J. Wallin, B.A. Meyerson and B. Linderoth (2004) Intrathecal clonidine potentiates suppression of tactile hypersensitivity by spinal cord stimulation in a model of neuropathy. Anesth. Analg. 99 135-139.
65. Z. Seltzer, R. Dubner and Y. Shir (1990) A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43 205-218.
66. M.P. Sindou, P. Mertens, U. Bendavid, L. García-Larrea and F. Mauguière (2003) Predictive value of somatosensory evoked potentials for long-lasting pain relief after spinal cord stimulation: practical use for patient selection. Neurosurgery 52 1374-1383.
67. Z.Y. Song, C. Ultenius, G. Schechtmann, B.A. Meyerson and B. Linderoth (2007) Downregulation of M4 but not M2 muscarinic receptors in the dorsal horn after peripheral nerve injury relates to responsiveness to SCS. Abstract 2nd International Congress on Neuropathic Pain, Berlin. Eur. J. Pain 11(Suppl. 1), 175.
68. C.O. Stiller, J.-G. Cui, W.T. O`Connor, E. Brodin, B.A. Meyerson and B. Linderoth (1996) Release of GABA in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats. Neurosurgery 39 367-375.
69. S. Tanaka, K.W. Barron, M.J. Chandler, B. Linderoth and R.D. Foreman (2003) Local cooling alters neural mechanisms producing changes in peripheral blood flow by spinal cord stimulation. Autonomic Neurosci. 104 117-127.
70. S. Tanaka, K.W. Barron, M.J. Chandler, B. Linderoth and R.D. Foreman (2003) Role of primary afferents in spinal cord stimulation-induced vasodilatation: characterization of fiber types. Brain Res. 959 191-198.
71. S. Tanaka, N. Komori, K.W. Barron, M.J. Chandler, B. Linderoth and R.D. Foreman (2004) Mechanisms of sustained cutaneous vasodilation induced by spinal cord stimulation. Auton. Neurosci. 114 55-60.
72. J. Wallin, J.-G. Cui, V. Yahknitsa, G. Schechtmann, B.A. Meyerson and B. Linderoth (2002) Gabapentin and pregabalin suppress tactile allodynia and potentiate spinal cord stimulation in a model of neuropathy. Eur. J. Pain 6 261-272.
73. J. Wallin, A. Fiska, A. Tjolsen, B. Linderoth and K. Hole (2003) Spinal cord stimulation inhibits long-term potentiation of spinal wide dynamic range neurons. Brain Res. 973 39-43.
74. X.L. Wang, H.M. Zhang, D.P. Li, S.R. Chen and H.L. Pan (2006) Dynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats. J. Physiol. 571 403-413.
75. G. Wasner, K. Heckmann, C. Maier and R. Baron (1999) Vascular abnormalities in acute reflex sympathetic dystrophy (CRPS I): complete inhibition of sympathetic nerve activity with recovery. Arch. Neurol. 56 613-620.
76. C. Woolf and T. Doubell (1994) The pathophysiology of chronic pain – increased sensitivity to low threshold A-beta fiber inputs. Curr. Opin. Neurobiol. 4 525-534.
77. C.J. Woolf, G.J. Bennett, M. Doherty, et al. (1998) Towards a mechanism-based classification of pain? Pain 77 227-229.
78. M. Wu, N. Komori, C. Qin, J. Farber, B. Linderoth and R.D. Foreman (2006) Sensory fibers containing vanilloid receptor-1 (VR-1) participate in spinal cord stimulation-induced vasodilation. Brain Res. 1107 177-184.
79. M. Wu, L. Linderoth and R.D. Foreman (2008) Putative mechanisms behind effects of spinal cord stimulation on vascular diseases: a review of experimental studies. Auton. Neurosci. 138 9-23.
80. V. Yakhnitsa, B. Linderoth and B.A. Meyerson (1999) Spinal cord stimulation attenuates dorsal horn neuronal hyperexcitability in a rat model of mononeuropathy. Pain 79 223-233.
81. H.M. Zhang, D.P. Li, S.R. Chen and H.L. Pan (2005) M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J. Pharmacol. Exp. Ther. 313 697-704.