Mammalian Models of Genetic Epilepsy Characterized by Sensory-Evoked Seizures and Generalized Seizure Susceptibility

Models of Seizures and Epilepsy

Volumn , Issue , 2006, Pages 261-271

  Jobe, Phillip C ^a   Browning, Ronald A ^b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882862777     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012088554-1/50022-0     Document Type: Chapter

References (94)

1. Brailowsky S., Silva B.C., Menini C., Riche D., Naquet R. Effects of localized, chronic GABA infusions into different cortical areas of the photosensitive baboon, Papio papio. Electroencephalogr Clin Neurophysiol 1989, 72:147-156.
2. Browning R.A., Wade D.R., Marcincyzk M., Long G.L., Jobe P.C. Regional brain abnormalities in norepinephrine uptake and dopmaine beta-hydroxylase activity in the genetically epilepsy-prone rat. J Pharmacol Exp Ther 1989, 249:229-235.
3. Browning R.A., Wang C., Lanker M.L., Jobe P.C. Electroshock-and pentylenetetrazol-induced seizures in genetically epilepsy-prone rats (GEPRs): differences in threshold and pattern. Epilepsy Res 1990, 6:1-11.
4. Browning R.A., Wang C., Nelson D.K., Jobe P.C. Effect of precollicular transection on audiogenic seizures in genetically epilepsyprone rats. Exp Neurol 1999, 155:295-301.
5. Bourn W.M., Garrett R.L. Increased susceptibility of audiogenic rats to barbital withdrawal convulsions. Pharmacol Biochem Behav 1983, 19:839-841.
6. Buchhalter J.R. Animal models of inherited epilepsy. Epilepsia 1993, 34(suppl 3):S31-S41.
7. Coffey L.L., Reith M.E.A., Chen N.H., Jobe P.C., Mishra P.K. Amygdala kindling of forebrain seizures and the occurrence of brainstem seizures in genetically epilepsy-prone rats. Epilepsia 1996, 37:188-197.
8. Corcoran M.E., Cain D.P., Wada J.A. Photically induced seizures in the yellow baboon, Papio cynocephalus. Can J Neurol Sci 1979, 6:129-131.
9. Cure D., Rasmussen T., Jasper H. Activation of seizures and electroencephalographic disturbances in epileptic and in control subjects with "metrazol". Arch Neurol Psychiatry 1948, 59:691-717.
10. Dailey J.W., Jobe P.C. Anticonvulsant drugs and the genetically epilepsy-prone rat. Fed Proc 1985, 44:2640-2644.
11. Dailey J.W., Mishra P.K., Ko K.H., Penny J.E., Jobe P.C. Noradrenergic abnoramalities in the central nervous system of seizurenaïve genetically epilepsy-prone rats. Epilepsia 1991, 32:168-173.
12. Dailey J.W., Mishra P.K., Ko K.H., Penny J.E., Jobe P.C. Serotonergic abnormalities in the central nervous systems of seizure-naïve genetically eplepsy-prone rats. Life Sci 1992, 50:319-326.
13. Dailey J.W., Reigel C.E., Mishra P.K., Jobe P.C. Neurobiology of seizure predisposition in the genetically epilepsy-prone rat. Epilepsy Res 1989, 3:3-17.
14. DeSarro A., DeSarro G.B. Responsiveness of genetically epilspy-prone rats to aminophylline-induced seizures and interactions with quinolones. Neuropharmacology 1991, 30:169-176.
15. Evans M.S., Biola-McCabe K.E., Caspary D.M., Faingold C.L. Loss of synaptic inhibition during repetitive stimulation in geneticall epeilspy-prone rats (GEPR). Epilepsy Res 1994, 18:97-105.
16. Faingold C.L. Emergent properties of CNS neuronal networks as targets for pharmacology: application to anticonvulsant, drug action. Prog Neurobiol 2004, 72:55-85.
17. Faingold C.L., Gehlbach G., Caspary D.M. Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat. Exp Neurol 1986, 93:145-159.
18. Faingold C.L., Travis M.A., Gehlback G., Hoffmann W.E., Jobe P.C., Laird H.E., Caspary D.M. Neuronal response abnormalities in the inferior colliculus of the genetically epilepsy-prone rat. Electroencephalogr Clin Neurophysiol 1986, 63:296-305.
19. Faingold C.L., Marcinczyk M.F., Casebeer D.J., Randall M.E., Arneric S.P., Browning RA. GABA in the inferior colliculus plays a critical role in control of audiogenic seizures. Brain Res 1994, 640:40-47.
20. Fischer-Williams M., Poncet M., Riche D., Naquet R. Light induced epilepsy, in the baboon Papio papio: cortical and depth recordings. Electroencephalograph, Clin Neurophysiol 1968, 25:557-569.
21. Franck J.E., Ginter K.L., Schwartzkroin P.A. Developing genetically epilepsy-prone rats have an abnormal seizure response to flurothyl. Epilepsia 1989, 30:1-6.
22. Garcia-Cairasco N., Moraes M.F.D., Browning R.A., Mishra P.K., Jobe P.C. Precollicular transection and its effect on brainstem seizure in GEPR-9 role of cortex in brainstem seizure regulation. Soc Neurosci Abst 1998, 24:1211.
23. Goddard G.V., McIntyre D.C., Leech C.K. A permanent change in brain functiion resulting from daily electrical stimulation. Exp Neurol 1969, 25:295-330.
24. Hjeresen D.L., Franck J.E., Amend D.L. Ontogeny, of seizure incidence, latency, and severity in genetically epilepsy prone rats. Dev Psychobiol 1987, 20:355-363.
25. Holmes G.L., Thompson J.L., Marchi T.A., Gabriel P.S., Hogan M.A., Carl G.F., Feldman D.S. Effects of seizures on learning, memory and behavior in the genetically epilepsy-prone rat. Ann Neurol 1990, 27:24-32.
26. Jobe P.C. Common pathogenic mechanisms between depression and epilepsy: an experimental perspective. Epilepsy Behav 2003, 4:14-24.
27. Jobe P.C. Affective disorder and epilepsy comorbidity: Implications for development of treatments, preventions and diagnostic approaches. Clin EEG Neurosci 2004, 35:53-68.
28. Jobe P.C. Current and future therapeutic opportunicties in the comorbidity between the epilepsies and affective disorders. Clin EEG Neurosci 2004, 35:1-3.
29. Jobe P.C. Shared mechanisms of antidepressant and antiepileptic treatments: drugs and devices. Clin EEG Neurosci 2004, 35:25-37.
30. Jobe P.C., Dailey J.W. Genetically epilepsy-prone rats (GEPRs) in drug research. CNS Drug Rev 2000, 6:241-260.
31. Jobe P.C., Dailey J.W., Wernicke F.J. A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders. Crit Rev Neurobiol 1999, 13:217-356.
32. Jobe P.C., Ko K.H., Dailey J.W. Abnormalities in norepinephrine turnover rate in the central nervous system of the genetically epilepsy-prone rat. Brain Res 1984, 290:357-360.
33. Jobe P.C., Laird H.E. Neurotransmitter systems and the epilepsy models: distinguishing features and unifying principles. Neurotransmitters and Epilepsy 1987, 339. Humana Press, Clifton, NJ. P.C. Jobe, H.E. Laird (Eds.).
34. Jobe P.C., Mishra P.K., Browning R.A., et al. Noradrenergic abnormalities in the genetically epilepsy-prone rat. Brain Res Bull 1994, 35:493-504.
35. Jobe P.C., Mishra P.K., Ludvig N., Dailey J.W. Scope and contribution of genetic models to an understanding of the epilepsies. CRC Crit Rev Neurobiol 1991, 6:183-220.
36. Jobe P.C., Mishra P.K., Dailey J.W., Ko K.H., Reigh M.E.A. Genetic predisposition to partial (focal) seizures and to generalized tonic/clonic seizures: Interactions between seizure circuitry of the fore brain and brainstem. Genetics of Focal Epilepsies 1999, 251. John Libbey & Company, Avignon, France. S.F. Berkovic, P. Genton, E. Hirsch, F. Picard (Eds.).
37. Jobe P.C., Picchioni A.L., Chin L. Role of brain 5-hydroxytryptamine in audiogenic seizure in the rat. Life Sci 1973, 13:1-13.
38. Jobe P.C., Picchioni AL, Chin L. Role of brain norepinephrine in audiogenic seizure in the rat. J Pharmacol Exp Ther 1973, 184:1-10.
39. Kaplan H., Miezejeski C. Development of seizures in the mongolian gerbil ( Meriones unguiculatus). J Comp Physiol Psychol 1972, 81:267-273.
40. Kiesmann M., Marescaux C., Vergnes M., Micheletti G., Depaulis A., Warter J.M. Audiogenic seizures in Wistar rats before and after repeated audiotry stimuli: clinical, pharmacological, and electroencephalographic studies. J Neural Transm 1988, 72:235-244.
41. Killam E.K. Photomyoclonic seizures in the baboon, Papio papio. Fed Proc 1979, 38:2429-2433.
42. Killam E.K., Killam K.F. Evidence for neurotransmitter abnormalities related to seizure activity in the epileptic baboon. Fed Proc 1984, 43:2510-2515.
43. Killam K.F., Killam E.K., Naquet R. An animal model of light sensitive epileps. Electroencephalogr Clin Neurophysiol 1967, 22:497-513.
44. Killam K.F., Killam E.K., Naquet R. Mise en evidence chez certains singes d'un syndrome photomyoclonique. CR Acad Sci 1966, 262:1010-1012.
45. Killam K.F., Killam E.K., Naquet R. Etudes pharmacologiques realisees chez des singes presentant une activite E.E.G. paroxystique particuliere a la stimulation lumineuse intermittente. J. Physiol 1966, 58:543-544.
46. Killam K.F., Killam E.K., Naquet R. Study of responses evoked by intermittent light stimulation in monkeys presenting paroxysmal responses to this type of stimulation. Rev Neurol (Paris) 1966, 115:422-423.
47. Killam K.F., Naquet R., Bert J. Paroxysmal responses to intermittent light stimulation in a population of baboons ( Papio papio). Epilepsia 1966, 7:215-219.
48. King J.T., Lamotte C.C. El mouse as a model of focal epilepsy: a review. Epilepsia 1989, 30:257-265.
49. Kurtz B., Lehman J., Garlick P., Amberg J., Mishra P.K., Dailey J.W., Weber R.J., Jobe P.C. Penetrance and expressivity of genes involved in the development of epilepsy in the geneticaly epilepsyprone rat (GEPR). J Neurogenet 2001, 15:233-244.
50. Loskota W.J., Lomax P. The mongolian gerbil ( Meriones unguiculatus) as a model for the study of the epilepsies: EEG records of seizures. Electroencephalogr Clin Neurophysiol 1975, 38:597-604.
51. Loscher W. Genetic animal models of epilepsy as a unique resource for the evaluation of anticonvulsant drugs. a review. Methods Find Exp Clin Pharmacol 1984, 6:531-547.
52. Ludvig N., Moshe S.L. Different behavioral and electrographic effects of acoustic stimulation and dibutyryl cyclic AMP injection into, the inferior colliculus in normal and in genetically epilepsy-prone rats. Epilepsy Res 1989, 3:185-190.
53. Meldrum B.S., Anlezark G.M., Balzamo E., Horton R.W., Trimble M. Photically induced epilepsy in Papio papio as a model for drug studies. Adv Neurol 1975, 10:119-132.
54. Meldrum B.S., Chir B., Horton R.W., Toseland P.A. A primate model for testing anticonvulsant drugs. Arch Neurol 1975, 32:289-294.
55. Meldrum B.S., Balzamo E. Epilepsy in the photosensitive baboon, Papio papio, and drugs acting on cerebral GABA and serotonin mechanisms. Med Primatol 1972, Part II:282-288.
56. Meldrum B.S., Croucher M.J., Badman G., Collins J.F. Antiepileptic action of excitatory amine acid antagonists in the photosensitive baboon. Papio papio. Neurosci Lett 1983, 39:101-104.
57. Meldrum B., Horton R. Blockade of epileptic responses in the photosensitive baboon, Papio papio, by two irreversible inhibitors of GABA-transaminase, gamma-acetylenic GABA (4-amino-hex-5-ynoic acid) and gamma-vinyl GABA (4-amino-hex-5-enoic acid). Psychopharmacology 1978, 59:47-50.
58. Menini C., Silva Barrat C. Value of the monkey Papio papio for the study of epilepsy. Pathol Biol 1990, 38:205-213.
59. Merrill M.A., Clough R.W., Shaw T., Jobe P.C., Browning R.A. Brainstem (BS) seizure severity regulates forebrain FB seizure expression in the audiogenic kinding model. Soc Neurosci Abst 1998, 24(1):475. 13.
60. Millan M.H., Wardley-Smith B., Durmuller N., Meldrum B.S. The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono hepatanoate. Exp Neurol 1991, 112:317-320.
61. Mishra P.K., Dailey J.W., Reigel C.E., Jobe P.C. Audiogenic convulsions in moderate seizure genetically epilepsy-prone rats (GEPR-3s). Epilepsy Res 1989, 3:191-198.
62. Mishra P.K., Dailey J.W., Reigel C.E., Tomsic M.L., Jobe J.C. Sex-specific distinctions in audiogenic convulsions exhibited by severe seizure genetically epilepsy-prone rats (GEPR-9s). Epilepsy Res 1988, 2:309-316.
63. Moraes M.F., Chavali M., Mishra P.K., Jobe P.C., Garcia-Cairasco N. A comprehensive electrographic and behavioral analysis of generalized tonic-clonic seizures of GEPR-9s. Brain Res 2005, 1033:1-12.
64. Moraes M.F.D., Moraes C., Jobe P.C., Mishra P.K., Garcia-Cairasco N. Neural substrates correlated with the appearance of limbic seizures during repetitive acoustic stimulation of GEPRs. Soc Neurosci Abst 1998, 24(part 1):475.14.
65. Naquet R., Valin A. Focal discharges in photosensitive generalized epilepsy. Generalized Epilepsy: Neurobiological Approaches 1990, 273. Birkhauser, Boston. M. Avoli, P. Gloor, G. Kostopoulos, R. Naquet (Eds.).
66. Noebels, J. L. Fariello, R.G., Jobe, P.C., Lasley, S.M., and Marescaux, C. Genetic models of generalized epilepsy. In Epilepsy, A Comprehensive Textbook Ist ed. Eds. J. Engel Jr. and T.A. Pedley. pp 457-466. Phildelphia: Lippincott-Raven.
67. Paul L.A., Fried I., Watanabe K., Fosythe A.B., Scheibel A.B. Structural correlates of seizure behavior in the Mongolian gerbil. Science 1981, 213:924-926.
68. Pedley T.A., Horton R.W., Meldrum B.S. Electroencephalographic and behavioral effects of a GABA agonist (muscimol) on photosensitive epilepsy in the baboon, Papio papio. Epilepsia 1979, 20:409-416.
69. Reigel C.E., Dailey J.W., Jobe P.C. The genetically epilepsyprone rat: an overview of seizure-prone characteristics and responsiveness to anticonvulsant drugs. Life Sci 1986, 39:763-774.
70. Reigel C.E., Jobe P.C., Dailey J.W., Savage D.D. Ontogeny of sound-induced seizures in the genetically epilepsy-prone rat. Epilepsy Res 1989, 4:63-71.
71. Ribak C.E., Roberts R.C., Byun M.Y., Kim H.L. Anatomical and behavioral analyses of the inheritance of audiogenic seizures in the progeny of genetically epilepsy-prone and Sprague-Dawley rats. Epilepsy Res 1988, 2:345-355.
72. Ryu J.R., Jobe P.C., Milbrandt J.C., Mishra P.C., Clough R.W., Browning R.A., Dailey J.W., et al. Morphological deficits in noradrenergic neurons in GEPR-9s stem from abnormalities in both the locus coeruleus and its target tissues. Exp Neurol 1999, 156:84-91.
73. Savage D.D., Reigel C.E., Jobe P.C. Angular bundle kindling is accelerated in rats with a genetic predisposition to acoustic stimulus-induced seizures. Brain Res 1986, 376:412-415.
74. Savage D.D., Reigel C.E., Jobe P.C. The development of kindled seizures is accelerated in the genetically epilepsy-prone rat. Life Sci 1986, 39:879-886.
75. Schonfeld A.R., Glick S.D. Handling-induced seizures and rotational behavior in the Mongolian gerbil. Pharmacol Biochem Behav 1981, 14:507-516.
76. Schreiber R.A., Graham J.M. Audiogenic priming in DBA/2J and C57BL/6J mice: interactions among age, prime-to-test interval and index of seizure. Dev Psychobiol 1976, 9:57-66.
77. Seyfried T.N., Glaser G.H. A review of mouse mutants as genetic models of epilepsy. Epilepsia 1985, 26:143-150.
78. Seyfried T.N., Glaser G.H., Yu R.K., Palayoor S.T. Inherited convulsive disorders in mice. Adv Neurol 1986, 44:115-133.
79. Silva-Barrat C., Menini C. Photosensitive epilepsy of the baboon: A generalized epilepsy with a motor cortical origin. Generalized Epilepsy: Neurobiological Approaches 1990, 286. Birkhauser, Boston. M. Avoli, P. Gloor, G. Kostopoulos, R. Naquet (Eds.).
80. Suzdak P.D., Jansen J.A. A review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant GABA uptake inhibitor. Epilepsia 1995, 36:612-626.
81. Suzuki J., Nakamoto Y. Seizure patterns and electroencephalograms of El mouse. Electroencephalogr Clin Neurophysiol 1977, 43:299-311.
82. Szabo C.A., Leland M.M., Sztonak L., Restrepo S., Haines R., Mahaney M.A., Williams J.T. Scalp EEG for the diagnosis of epilepsy and photosensitivity in the baboon. Am J Primatol 2004, 62:95-106.
83. Thompson J.L., Carl G.F., Holmes G.L. Effect of age on seizure susceptibility in genetically epilepsy-prone rats (GEPR-9s). Epilepsia 1991, 32:161-167.
84. Vicari E. Fatal convulsive seizures in the DBA mouse strain. J Psychol 1951, 32:79-97.
85. Valin A., Bryere P., Naquet R. Convulsant effect of Ro 5-4864 a prepheral type benzodiazepine, on the baboon ( Papio papio). Neurosci Lett 1986, 66:210-214.
86. Valin A., Voltz C., Naquet R., Lloyd K.G. Effects of pharmacological manipulation on neurotrasmitter and other amino acid levels in the CSF of the Senegalese baboon Papio papio. Brain Res 1991, 538:15-23.
87. Wada J.A., Osawa T. Spontaneous recurrent seizure state induced by daily electric amygdaloid stimulation in Senegalese baboons ( Papio papio). Neurology 1976, 26:273-286.
88. Wada J.A., Osawa T., Mizoguchi T. Recurrent spontaneous seizure state induced by prefrontal kindling in senegalese baboons, Papio papio. Can J Neurol Sci 1975, 2:477-492.
89. Wada J.A., Terao A., Booker H.E. Longitudinal correlative analysis of epileptic baboon, Papio papio. Neurology 1972, 22.
90. Walczak, T.S., and Jayakar, P. Interictal EEG. In Epilepsy: A Comprehensive Textbook. 1st ed. Eds. J. Engel Jr. and T.A. Pedley. pp. 831-848. Philadelphia: Lippincott-Raven.
91. Weinberger S.B., Killam E.K. A comparison of the effects of chronically administered diazepam and phenobarbital and learning in the Papio papio model of epilepsy. Proc West Pharmacol Soc 1977, 20:173-177.
92. Weinberger S.B., Killam E.K. Learning and behavioral abnormalities in the seizure-prone baboon. Biol Psychiatry 1979, 14:525-535.
93. Zhang N., Walberg F., Laake J.H., Meldrum B.S., Ottersen O.P. Aspartate-like and glutamate-like immunoreactivities in the inferior olive and climbing fibre system: a light microscopic and semiquantitative electron microscopic study in rat and baboon ( Papio anubis). Neuroscience 1990, 38:61-80.
94. Zifkin B., Andermann F. Epilepsy with relfex seizures. The Treatment of Epilepsy: Principles and Practice 2001, 537. Lippincott Williams & Wilkins, Philadelphia. B. Wyllie (Ed.).