메뉴 건너뛰기




Volumn 11, Issue 1, 2013, Pages 45-51

Bisphosphonate drug holiday: Choosing appropriate candidates

Author keywords

Atypical fracture; Bisphosphonate; Drug holiday; Osteoporosis

Indexed keywords

ALENDRONIC ACID; ALKALINE PHOSPHATASE BONE ISOENZYME; BISPHOSPHONIC ACID DERIVATIVE; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN; IBANDRONIC ACID; PARATHYROID HORMONE[1-34]; PLACEBO; PROCOLLAGEN TYPE 1 AMINOPROPEPTIDE; RALOXIFENE; RISEDRONIC ACID; UNCLASSIFIED DRUG; ZOLEDRONIC ACID;

EID: 84882860054     PISSN: 15441873     EISSN: 15442241     Source Type: Journal    
DOI: 10.1007/s11914-012-0129-9     Document Type: Article
Times cited : (26)

References (43)
  • 1
    • 84882820457 scopus 로고    scopus 로고
    • National Osteoporosis Foundation: America's bone health: the state of osteoporosis and low bone mass in our nation. Washington, DC. 2002
    • National Osteoporosis Foundation: America's bone health: the state of osteoporosis and low bone mass in our nation. Washington, DC. 2002. http://www.nof.org/
  • 2
    • 34247194211 scopus 로고    scopus 로고
    • Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025
    • 17144789 10.1359/jbmr.061113
    • Burge R, Dawson-Hughes B, Solomon DH, et al. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007;22:465-75.
    • (2007) J Bone Miner Res , vol.22 , pp. 465-475
    • Burge, R.1    Dawson-Hughes, B.2    Solomon, D.H.3
  • 3
    • 0032821407 scopus 로고    scopus 로고
    • Survival after hip fracture: Short- and long-term excess mortality according to age and gender
    • 10501783 10.1007/s001980050197 1:STN:280:DyaK1MvjtFKhtg%3D%3D
    • Forsen L, Sogaard AJ, Meyer HE, et al. Survival after hip fracture: short- and long-term excess mortality according to age and gender. Osteoporos Int. 1999;10:73-8.
    • (1999) Osteoporos Int , vol.10 , pp. 73-78
    • Forsen, L.1    Sogaard, A.J.2    Meyer, H.E.3
  • 4
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
    • 8950879 10.1016/S0140-6736(96)07088-2 1:CAS:528:DyaK2sXisFCktQ%3D%3D
    • Black DM, Cummings SR, Karpf DB, et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet. 1996;348:1535-41.
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3
  • 5
    • 0033552255 scopus 로고    scopus 로고
    • Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: A randomized controlled trial. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group
    • 10527181 10.1001/jama.282.14.1344 1:CAS:528:DyaK1MXmvFansr0%3D
    • Harris ST, Watts NB, Genant HK, et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 1999;282:1344-52.
    • (1999) JAMA , vol.282 , pp. 1344-1352
    • Harris, S.T.1    Watts, N.B.2    Genant, H.K.3
  • 6
    • 4544262219 scopus 로고    scopus 로고
    • Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis
    • 10.1359/JBMR.040325 1:CAS:528:DC%2BD2cXntFGqurw%3D
    • Chesnut IC, Skag A, Christiansen C, et al. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res. 2004;19:1241-9.
    • (2004) J Bone Miner Res , vol.19 , pp. 1241-1249
    • Chesnut, I.C.1    Skag, A.2    Christiansen, C.3
  • 7
    • 0035253489 scopus 로고    scopus 로고
    • Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group
    • 11172164 10.1056/NEJM200102013440503 1:CAS:528:DC%2BD3MXht1Wlu7g%3D
    • McClung MR, Geusens P, Miller PD, et al. Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N Engl J Med. 2001;344:333-40.
    • (2001) N Engl J Med , vol.344 , pp. 333-340
    • McClung, M.R.1    Geusens, P.2    Miller, P.D.3
  • 8
    • 84858062241 scopus 로고    scopus 로고
    • An evaluation of the use of oral bisphosphonates and risk of esophageal cancer
    • 22333262 10.1345/aph.1Q482
    • Haber SL, McNatty D. An evaluation of the use of oral bisphosphonates and risk of esophageal cancer. Ann Pharmacother. 2012;46:419-23.
    • (2012) Ann Pharmacother , vol.46 , pp. 419-423
    • Haber, S.L.1    McNatty, D.2
  • 9
    • 77956542068 scopus 로고    scopus 로고
    • Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: Case-control analysis within a UK primary care cohort
    • 20813820 10.1136/bmj.c4444
    • Green J, Czanner G, Reeves G, et al. Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort. BMJ. 2010;341:c4444.
    • (2010) BMJ , vol.341 , pp. 4444
    • Green, J.1    Czanner, G.2    Reeves, G.3
  • 10
    • 77955369368 scopus 로고    scopus 로고
    • Exposure to oral bisphosphonates and risk of esophageal cancer
    • 20699457 10.1001/jama.2010.1098 1:CAS:528:DC%2BC3cXhtVelsbbO
    • Cardwell CR, Abnet CC, Cantwell MM, et al. Exposure to oral bisphosphonates and risk of esophageal cancer. JAMA. 2010;304:657-63.
    • (2010) JAMA , vol.304 , pp. 657-663
    • Cardwell, C.R.1    Abnet, C.C.2    Cantwell, M.M.3
  • 11
    • 0042861578 scopus 로고    scopus 로고
    • Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic
    • 12966493 10.1016/S0278-2391(03)00720-1
    • Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003;61:1115-7.
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1115-1117
    • Marx, R.E.1
  • 12
    • 12944323192 scopus 로고    scopus 로고
    • Seven years of treatment with risedronate in women with postmenopausal osteoporosis
    • 15455188 10.1007/s00223-004-0286-7 1:STN:280:DC%2BD2M%2FisFSktA%3D%3D
    • Mellstrom DD, Sorensen OH, Goemaere S, et al. Seven years of treatment with risedronate in women with postmenopausal osteoporosis. Calcif Tissue Int. 2004;75:462-8.
    • (2004) Calcif Tissue Int , vol.75 , pp. 462-468
    • Mellstrom, D.D.1    Sorensen, O.H.2    Goemaere, S.3
  • 13
    • 82055162846 scopus 로고    scopus 로고
    • Managing the care of patients receiving antiresorptive therapy for prevention and treatment of osteoporosis: Executive summary of recommendations from the American Dental Association Council on Scientific Affairs
    • 22041409 1:CAS:528:DC%2BC3MXhs1Sks7vK
    • Hellstein JW, Adler RA, Edwards B, et al. Managing the care of patients receiving antiresorptive therapy for prevention and treatment of osteoporosis: executive summary of recommendations from the American Dental Association Council on Scientific Affairs. J Am Dent Assoc. 2011;142:1243-51.
    • (2011) J Am Dent Assoc , vol.142 , pp. 1243-1251
    • Hellstein, J.W.1    Adler, R.A.2    Edwards, B.3
  • 14
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • 17663640 10.1359/jbmr.0707onj
    • Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22:1479-91.
    • (2007) J Bone Miner Res , vol.22 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 15
    • 34247866550 scopus 로고    scopus 로고
    • Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
    • 17476007 10.1056/NEJMoa067312 1:CAS:528:DC%2BD2sXltVSktLc%3D
    • Black DM, Delmas PD, Eastell R, et al. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med. 2007;356:1809-22.
    • (2007) N Engl J Med , vol.356 , pp. 1809-1822
    • Black, D.M.1    Delmas, P.D.2    Eastell, R.3
  • 16
    • 0034530951 scopus 로고    scopus 로고
    • Fracture risk reduction with alendronate in women with osteoporosis: The Fracture Intervention Trial. FIT Research Group
    • 11095442 10.1210/jc.85.11.4118 1:CAS:528:DC%2BD3cXotlWnurw%3D
    • Black DM, Thompson DE, Bauer DC, et al. Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab. 2000;85:4118-24.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4118-4124
    • Black, D.M.1    Thompson, D.E.2    Bauer, D.C.3
  • 17
    • 84857368424 scopus 로고    scopus 로고
    • Use of bisphosphonate and risk of atrial fibrillation in older women with osteoporosis
    • 21431993 10.1007/s00198-011-1608-z 1:CAS:528:DC%2BC38XktVOltg%3D%3D
    • Rhee CW, Lee J, Oh S, et al. Use of bisphosphonate and risk of atrial fibrillation in older women with osteoporosis. Osteoporos Int. 2012;23:247-54.
    • (2012) Osteoporos Int , vol.23 , pp. 247-254
    • Rhee, C.W.1    Lee, J.2    Oh, S.3
  • 18
    • 84857356298 scopus 로고    scopus 로고
    • Alendronate and atrial fibrillation: A meta-analysis of randomized placebo-controlled clinical trials
    • 21369791 10.1007/s00198-011-1546-9 1:CAS:528:DC%2BC38XktVOlsA%3D%3D
    • Barrett-Connor E, Swern AS, Hustad CM, et al. Alendronate and atrial fibrillation: a meta-analysis of randomized placebo-controlled clinical trials. Osteoporos Int. 2012;23:233-45.
    • (2012) Osteoporos Int , vol.23 , pp. 233-245
    • Barrett-Connor, E.1    Swern, A.S.2    Hustad, C.M.3
  • 19
    • 84882922657 scopus 로고    scopus 로고
    • FDA. Update of safety review follow-up to the October 1, 2007 'Early Communication about the Ongoing Safety Review of Bisphosphonates'
    • FDA. Update of safety review follow-up to the October 1, 2007 'Early Communication about the Ongoing Safety Review of Bisphosphonates'. http://www.fda.gov/Drugs/DrugSafety/ PostmarketDrugSafetyInformationforPatientsandProviders/ DrugSafetyInformationforHeathcareProfessionals/ucm136201.htm
  • 20
    • 79955722153 scopus 로고    scopus 로고
    • Bisphosphonate use and atypical fractures of the femoral shaft
    • 21542743 10.1056/NEJMoa1010650 1:CAS:528:DC%2BC3MXlvFymtLs%3D This study demonstrated the association of atypical femoral fractures with longer duration of bisphosphonate use
    • Schilcher J, Michaelsson K, Aspenberg P. Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med. 2011;364:1728-37. This study demonstrated the association of atypical femoral fractures with longer duration of bisphosphonate use.
    • (2011) N Engl J Med , vol.364 , pp. 1728-1737
    • Schilcher, J.1    Michaelsson, K.2    Aspenberg, P.3
  • 21
    • 84868707203 scopus 로고    scopus 로고
    • Incidence of atypical nontraumatic diaphyseal fractures of the femur
    • 22836783 10.1002/jbmr.1719
    • Dell RM, Adams AL, Greene DF, et al. Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res. 2012;27:2544-50.
    • (2012) J Bone Miner Res , vol.27 , pp. 2544-2550
    • Dell, R.M.1    Adams, A.L.2    Greene, D.F.3
  • 22
    • 77952314262 scopus 로고    scopus 로고
    • Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur
    • 20335571 10.1056/NEJMoa1001086 1:CAS:528:DC%2BC3cXmtVSrsr4%3D This was a secondary analysis of 3 RCTs showing that atypical fractures were a rare occurrence and were not associated with use of bisphosphonates
    • Black DM, Kelly MP, Genant HK, et al. Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur. N Engl J Med. 2010;362:1761-71. This was a secondary analysis of 3 RCTs showing that atypical fractures were a rare occurrence and were not associated with use of bisphosphonates.
    • (2010) N Engl J Med , vol.362 , pp. 1761-1771
    • Black, D.M.1    Kelly, M.P.2    Genant, H.K.3
  • 23
    • 84882886418 scopus 로고    scopus 로고
    • FDA Fosamax, Fosamax Plus D, Actonel, Actonel with calcium, Boniva, Atelvia, and Reclast. October 13, 2010
    • FDA. Bisphosphonates (Osteoporosis drugs): label change - atypical fractures update. Fosamax, Fosamax Plus D, Actonel, Actonel with calcium, Boniva, Atelvia, and Reclast. October 13, 2010. http://www.fda.gov/Drugs/ DrugSafety/ucm229009.htm
    • Bisphosphonates (Osteoporosis Drugs): Label Change - Atypical Fractures Update
  • 24
    • 0001075697 scopus 로고
    • Clinical pharmacology of alendronate sodium
    • M. Gibaldi D. Perrier (eds) Marcel Dekker New York
    • Gibaldi M, Perrier D. Clinical pharmacology of alendronate sodium. In: Gibaldi M, Perrier D, editors. Pharmacokinetics. New York: Marcel Dekker; 1982. p. 145-98.
    • (1982) Pharmacokinetics , pp. 145-198
    • Gibaldi, M.1    Perrier, D.2
  • 25
    • 33845890326 scopus 로고    scopus 로고
    • Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Long-term Extension (FLEX): A randomized trial
    • 17190893 10.1001/jama.296.24.2927 1:CAS:528:DC%2BD2sXnvVGh
    • Black DM, Schwartz AV, Ensrud KE, et al. Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA. 2006;296:2927-38.
    • (2006) JAMA , vol.296 , pp. 2927-2938
    • Black, D.M.1    Schwartz, A.V.2    Ensrud, K.E.3
  • 26
    • 84856184102 scopus 로고    scopus 로고
    • The effect of 3 vs 6 years of zoledronic acid treatment of osteoporosis: A randomized extension to the HORIZON-Pivotal Fracture Trial (PFT)
    • 22161728 10.1002/jbmr.1494 1:CAS:528:DC%2BC38XhtV2ks7g%3D This study provided extension data for Zoledronic acid
    • Black DM, Reid IR, Boonen S, et al. The effect of 3 vs 6 years of zoledronic acid treatment of osteoporosis: a randomized extension to the HORIZON-Pivotal Fracture Trial (PFT). J Bone Miner Res. 2012;27:243-54. This study provided extension data for Zoledronic acid.
    • (2012) J Bone Miner Res , vol.27 , pp. 243-254
    • Black, D.M.1    Reid, I.R.2    Boonen, S.3
  • 28
    • 77951634320 scopus 로고    scopus 로고
    • Long-term use of bisphosphonates in osteoporosis
    • 20173017 10.1210/jc.2009-1947 1:CAS:528:DC%2BC3cXltFSgurk%3D
    • Watts NB, Diab DL. Long-term use of bisphosphonates in osteoporosis. J Clin Endocrinol Metab. 2010;95:1555-65.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1555-1565
    • Watts, N.B.1    Diab, D.L.2
  • 29
    • 84861705331 scopus 로고    scopus 로고
    • Bisphosphonates for osteoporosis - Where do we go from here?
    • 22571168 10.1056/NEJMp1202619 1:CAS:528:DC%2BC38XosFGjur0%3D This is the FDA advisory which reviewed extension data and discussed the concern regarding atypical femoral fractures
    • Whitaker M, Guo J, Kehoe T, et al. Bisphosphonates for osteoporosis - where do we go from here? N Engl J Med. 2012;366:2048-51. This is the FDA advisory which reviewed extension data and discussed the concern regarding atypical femoral fractures.
    • (2012) N Engl J Med , vol.366 , pp. 2048-2051
    • Whitaker, M.1    Guo, J.2    Kehoe, T.3
  • 30
    • 84861668653 scopus 로고    scopus 로고
    • Continuing bisphosphonate treatment for osteoporosis - For whom and for how long?
    • 22571169 10.1056/NEJMp1202623 1:CAS:528:DC%2BC38Xos1equrg%3D This is the response to FDA advisory and provides guidance in selecting appropriate candidates for drug holiday
    • Black DM, Bauer DC, Schwartz AV, et al. Continuing bisphosphonate treatment for osteoporosis - for whom and for how long? N Engl J Med. 2012;366:2051-3. This is the response to FDA advisory and provides guidance in selecting appropriate candidates for drug holiday.
    • (2012) N Engl J Med , vol.366 , pp. 2051-2053
    • Black, D.M.1    Bauer, D.C.2    Schwartz, A.V.3
  • 31
    • 77952331323 scopus 로고    scopus 로고
    • Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: The FLEX trial
    • 20200926 10.1002/jbmr.11 1:CAS:528:DC%2BC3cXnt1Kisrc%3D
    • Schwartz AV, Bauer DC, Cummings SR, et al. Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial. J Bone Miner Res. 2010;25:976-82.
    • (2010) J Bone Miner Res , vol.25 , pp. 976-982
    • Schwartz, A.V.1    Bauer, D.C.2    Cummings, S.R.3
  • 32
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy
    • 18214569 10.1007/s00198-007-0540-8 1:CAS:528:DC%2BD1cXltFyjurw%3D
    • Russell RG, Watts NB, Ebetino FH, et al. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int. 2008;19:733-59.
    • (2008) Osteoporos Int , vol.19 , pp. 733-759
    • Russell, R.G.1    Watts, N.B.2    Ebetino, F.H.3
  • 33
    • 33646089442 scopus 로고    scopus 로고
    • Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite
    • 16046206 10.1016/j.bone.2005.05.003 1:CAS:528:DC%2BD28XjvFSjtr4%3D
    • Nancollas GH, Tang R, Phipps RJ, et al. Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite. Bone. 2006;38:617-27.
    • (2006) Bone , vol.38 , pp. 617-627
    • Nancollas, G.H.1    Tang, R.2    Phipps, R.J.3
  • 34
    • 4344568083 scopus 로고    scopus 로고
    • Bone safety of long-term bisphosphonate treatment
    • 15324532 10.1185/030079904125004475 1:CAS:528:DC%2BD2cXotFyiurc%3D
    • Rodan G, Reszka A, Golub E, et al. Bone safety of long-term bisphosphonate treatment. Curr Med Res Opin. 2004;20:1291-300.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1291-1300
    • Rodan, G.1    Reszka, A.2    Golub, E.3
  • 36
    • 17744399512 scopus 로고    scopus 로고
    • Alendronate in early postmenopausal women: Effects on bone mass during long-term treatment and after withdrawal. Alendronate Osteoporosis Prevention Study Group
    • 10770187 10.1210/jc.85.4.1492 1:CAS:528:DC%2BD3cXisFOquro%3D
    • Ravn P, Weiss SR, Rodriguez-Portales JA, et al. Alendronate in early postmenopausal women: effects on bone mass during long-term treatment and after withdrawal. Alendronate Osteoporosis Prevention Study Group. J Clin Endocrinol Metab. 2000;85:1492-7.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1492-1497
    • Ravn, P.1    Weiss, S.R.2    Rodriguez-Portales, J.A.3
  • 37
    • 84876298072 scopus 로고    scopus 로고
    • Biomarkers of bone turnover in diagnosis and therapy of osteoporosis: A consensus advice from an Austrian working group
    • Bieglmayer C, Dimai HP, Gasser RW, et al. Biomarkers of bone turnover in diagnosis and therapy of osteoporosis: a consensus advice from an Austrian working group. Wiener Medizinische Wochenschrift. 2012;162:464-77.
    • (2012) Wiener Medizinische Wochenschrift , vol.162 , pp. 464-477
    • Bieglmayer, C.1    Dimai, H.P.2    Gasser, R.W.3
  • 38
    • 84878885708 scopus 로고    scopus 로고
    • Evaluation of urinary N-telopeptide of type i collagen measurements in the management of osteoporosis in clinical practice
    • doi: 10.1007/s00198-012-2097-4
    • Baxter I, Rogers A, Eastell R, et al. Evaluation of urinary N-telopeptide of type I collagen measurements in the management of osteoporosis in clinical practice. Osteoporosis International. 2012. doi: 10.1007/s00198-012-2097-4
    • (2012) Osteoporosis International
    • Baxter, I.1    Rogers, A.2    Eastell, R.3
  • 39
    • 0033839670 scopus 로고    scopus 로고
    • Clinical use of biochemical markers of bone remodeling: Current status and future directions
    • 10982161 10.1007/s001980070088 1:STN:280:DC%2BD3cvotFSitA%3D%3D
    • Looker AC, Bauer DC, Chesnut 3rd CH, et al. Clinical use of biochemical markers of bone remodeling: current status and future directions. Osteoporos Int. 2000;11:467-80.
    • (2000) Osteoporos Int , vol.11 , pp. 467-480
    • Looker, A.C.1    Bauer, D.C.2    Chesnut III, C.H.3
  • 40
    • 84859167960 scopus 로고    scopus 로고
    • Current recommendations for laboratory testing and use of bone turnover markers in management of osteoporosis
    • 22389876 10.3343/alm.2012.32.2.105 1:CAS:528:DC%2BC38Xmt1Cis7g%3D
    • Lee J, Vasikaran S. Current recommendations for laboratory testing and use of bone turnover markers in management of osteoporosis. Ann Lab Med. 2012;32:105-12.
    • (2012) Ann Lab Med. , vol.32 , pp. 105-112
    • Lee, J.1    Vasikaran, S.2
  • 41
    • 34548126988 scopus 로고    scopus 로고
    • Prediction of bone loss using biochemical markers of bone turnover
    • 17440674 10.1007/s00198-007-0379-z 1:STN:280:DC%2BD2svptFajuw%3D%3D
    • Lenora J, Ivaska KK, Obrant KJ, et al. Prediction of bone loss using biochemical markers of bone turnover. Osteoporos Int. 2007;18:1297-305.
    • (2007) Osteoporos Int , vol.18 , pp. 1297-1305
    • Lenora, J.1    Ivaska, K.K.2    Obrant, K.J.3
  • 42
    • 78651493109 scopus 로고    scopus 로고
    • Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards
    • 21184054 10.1007/s00198-010-1501-1 1:STN:280:DC%2BC3M7lt12jtA%3D%3D
    • Vasikaran S, Eastell R, Bruyere O, et al. Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards. Osteoporos Int. 2011;22:391-420.
    • (2011) Osteoporos Int , vol.22 , pp. 391-420
    • Vasikaran, S.1    Eastell, R.2    Bruyere, O.3
  • 43
    • 79952394479 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis
    • 21224201 These are current endocrine guidelines on management of osteoporosis
    • Watts NB, Bilezikian JP, Camacho PM, et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract. 2010;16 Suppl 3:1-37. These are current endocrine guidelines on management of osteoporosis.
    • (2010) Endocr Pract , vol.16 , Issue.SUPPL. 3 , pp. 1-37
    • Watts, N.B.1    Bilezikian, J.P.2    Camacho, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.