New mirsinane-type diterpenes from Euphorbia microsciadia Boiss. with inhibitory effect on VEGF-induced angiogenesis

Journal of Natural Medicines

Volumn 67, Issue 2, 2013, Pages 327-332

  Ghanadian, Syed Mustafa ^a   Ayatollahi, Abdul Majid ^b   Afsharypuor, Suleiman ^a   Javanmard, Shaghayegh Haghjooy ^c   Dana, Nasim ^c  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anti angiogenesis activity; Euphorbia microsciadia; Myrsinane diterpenoid

Indexed keywords

3 O PROPIONYL 5,10,14 O TRIACETYL 8 O (2' METHYLBUTANOYL)CYCLOMYRSINOL; 3,5,10,14,15 O PENTAACETYL 8 O ISOBUTANOYLCYCLOMYRSINOL; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; DITERPENE; EUPHORBIA MICROSCIADIA EXTRACT; METHANOL; PLANT EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; EUPHORBIA; EUPHORBIA MICROSCIADIA; FLOWER; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; IRAN; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; UMBILICAL VEIN ENDOTHELIAL CELL;

CELLS, CULTURED; DITERPENES; ENDOTHELIAL CELLS; EUPHORBIA; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PLANT EXTRACTS; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84882847279     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-012-0686-3     Document Type: Article

References (13)

1. Appendino G, Jakupovic S, Tron CG, Jakupovic J, Milon V, Ballero M (1998) Macrocyclic diterpenoids from Euphorbia semiperfoliata. J Nat Prod 61:749-756
2. Ayatollahi AM, Ghanadian M, Mesaik MA, Omer MA, Afsharypuor S, Kobarfard F, Mirza-taheri M (2010) New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity. J Asian Nat Prod Res 12:1020-1025
3. Ebn-e Sina A (1998) Ghanoon dar Teb, vol 5. Soroush, Tehran
4. Hussain S, Slevin M, Mesaik MA, Choudhary MI, Elosta AH, Matou S, Ahmed N, West D, Gaffney J (2008) Cheiradone: a vascular endothelial cell growth factor receptor antagonist. BMC Cell Biol 29:7-9
5. Tugues S, Koch S, Gualandi L, Li X, Claesson-Welsh L (2011) Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer. Mol Aspects Med 32:88-111
6. Viquar-Uddin A, Jassbi AR (1999) New diterpenoids from Euphorbia teheranica. J Nat Prod 62:1016-1018
7. Wang H, Zhang X, Zhou Y, Peng S, Zhou D, Ding L (2008) Two new diterpenes from Euphorbia kansuensis. Fitoterapia 79:262-266
8. Li J, Xu L (2010) New cytotoxic myrsinane-type diterpenes from Euphorbia prolifera. Helv Chim Acta 93:746-1752
9. Ayatollahi AM, Ghanadian M, Afsharypuor S, Choudhary MI, Kobarfard F, Rahmati M (2010) Two new lathyrane type diterpenoids from Euphorbia aellenii. Fitoterapia 81:891-893
10. Arnaoutova I, Kleinman HK (2010) In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract. Nat Protoc 5:628-635
11. Niemisto A, Dunmire V, Yli-Harja O, Zhang W, Shmulevich I (2005) Robust quantification of in vitro angiogenesis through image analysis. IEEE Trans Med Imaging 24:549-553
12. Scholz G, Pohl I, Genschow E, Klemm M, Spielmann H (1999) Embryotoxicity screening using embryonic stem cells in vitro: correlation to in vivo teratogenicity. Cells Tissues Organs 165:203-211
13. Ahmadvand D, Rahbarizadeh F, Jafari Iri-Sofla F, Namazi G, Khaleghi S, Geramizadeh B, Pasalar P, Karimi H, Aghaee Bakhtiari SH (2010) Inhibition of angiogenesis by recombinant VEGF receptor fragments. Lab Med 41:417-422