Bicuspid aortic valve aortopathy: Genetics, pathophysiology and medical therapy

Interactive Cardiovascular and Thoracic Surgery

Volumn 17, Issue 3, 2013, Pages 554-559

  Abdulkareem, Nada ^a   Smelt, Jeremy ^a   Jahangiri, Marjan ^a  

^a ST GEORGE'S UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Aortic aneurysm; Aortopathy; Bicuspid aortic valve; Genetics; Medical therapy

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXYCYCLINE; FIBROBLAST GROWTH FACTOR 8; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOSARTAN; MATRIX METALLOPROTEINASE; NOTCH1 RECEPTOR; SMAD3 PROTEIN; TRANSCRIPTION FACTOR GATA 5; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ACTA2 GENE; AORTA ANEURYSM; ARTICLE; ASCENDING AORTA; BICUSPID AORTIC VALVE; CARDIOVASCULAR RISK; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; FBN1 GENE; FLNA GENE; GATA5 GENE; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENOTYPE PHENOTYPE CORRELATION; HEART HEMODYNAMICS; HUMAN; MUTATOR GENE; MYH11 GENE; NONHUMAN; NOTCH1 GENE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMAD3 GENE; SYSTEMATIC REVIEW; TGFBR1 GENE; TGFBR2 GENE;

AORTIC ANEURYSM; AORTOPATHY; BICUSPID AORTIC VALVE; GENETICS; MEDICAL THERAPY;

AORTIC ANEURYSM; AORTIC VALVE; GENETIC PREDISPOSITION TO DISEASE; HEART VALVE DISEASES; HEMODYNAMICS; HUMANS; PHENOTYPE; RISK FACTORS; TREATMENT OUTCOME;

EID: 84882803561     PISSN: 15699293     EISSN: 15699285     Source Type: Journal    
DOI: 10.1093/icvts/ivt196     Document Type: Article

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