Neuraxial block, death and serious cardiovascular morbidity in the POISE trial

British Journal of Anaesthesia

Volumn 111, Issue 3, 2013, Pages 382-390

  Leslie, K ^a,b   Myles, P ^c,d,e   Devereaux, P ^f   Williamson, E ^b,d   Rao Melancini, P ^g   Forbes, A ^d   Xu, S ^h   Foex, P ⁱ   Pogue, J ^g   Arrieta, M ^j,k   Bryson, G ^l   Paul, J ^f   Paech, M ^m,n   Merchant, R ^o   Choi, P ^p   Badner, N ^q   Peyton, P ^b,r   Sear, J ⁱ   Yang, H ^s  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ALFRED HOSPITAL   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL   (Australia)

^f MCMASTER UNIVERSITY   (Canada)

^g MCMASTER UNIVERSITY   (Canada)

^h PEKING UNION MEDICAL COLLEGE   (China)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

^j UNIVERSIDAD MILITAR NUEVA GRANADA   (Colombia)

^k HOSPITAL MILITAR CENTRAL   (Colombia)

^l UNIVERSITY OF OTTAWA   (Canada)

^m UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁿ KING EDWARD MEMORIAL HOSPITAL   (Australia)

^o ROYAL COLUMBIAN HOSPITAL   (Canada)

^p UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^q UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^r AUSTIN HOSPITAL   (Australia)

^s UNIVERSITY OF OTTAWA   (Canada)

more..

Author keywords

anaesthesia, epidural; anaesthesia, spinal; death; myocardial infarction; stroke

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL SUCCINATE; NITROUS OXIDE; PLACEBO;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CONFIDENCE INTERVAL; CONTROLLED STUDY; EPIDURAL ANESTHESIA; FEMALE; GENERAL ANESTHESIA; HEART ARREST; HEART DEATH; HEART INFARCTION; HUMAN; HYPOTENSION; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MULTICENTER STUDY; NERVE BLOCK; NEURAXIAL BLOCK; POST HOC ANALYSIS; PRIORITY JOURNAL; PROPENSITY SCORE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SURGICAL PATIENT; TREATMENT OUTCOME;

EID: 84882778760     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aet120     Document Type: Article

References (29)

1. Friese H, Van Aken H. The risks and benefits of thoracic epidural anaesthesia. Br J Anaesth 2011; 107: 859-68
2. Beattie W, Badner N, Choi P. Epidural analgesia reduces postoperative myocardial infarction: A meta-Analysis. Anesth Analg 2001; 93: 853-8
3. Rigg J, Jamrozik K, Myles P, et al. Epidural anaesthesia and analgesia and outcome of major surgery: A randomised trial. Lancet 2002; 359: 1276-82
4. Popping D, Elia N, Marret E, Remy C, Tramer M. Protective effects of epidural analgesia on pulmonary complications after abdominal and thoracic surgery: A meta-Analysis. Arch Surg 2008; 143: 990-9
5. Rodgers A, Walker N, Schug S, et al. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results from overview of randomised trials. Br Med J 2000; 321: 1-12
6. Urwin S, Parker M, Griffiths R. General versus regional anaesthesia for hip fracture surgery: A meta-Analysis of randomized trials. Br J Anaesth 2000; 84: 450-5
7. Davies R, Myles P, Graham J. A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy-A systematic review and meta-Analysis of randomized trials. Br J Anaesth 2006; 96: 418-26
8. Choi P, Beattie W, Bryson G, Paul J, Yang H. Effects of epidural blockade may be difficult to study using large randomized controlled trials: The PeriOperative Epidural Trial (POET) Pilot Study. PLoS ONE 2009; 4: E4644
9. McPeek B. Inference, generalizability and a major change in anesthetic practice. Anesthesiology 1987; 66: 723-4
10. Park W, Thompson J, Lee K. Effect of epidural anesthesia and analgesia on perioperative outcomes. Ann Surg 2001; 234: 560-71
11. Leslie K, Myles P, Devereaux P, et al. Nitrous oxide and serious morbidity and mortality in the POISE Trial. Anesth Analg 2013; 116: 1034-40
12. POISE Trial Investigators. Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) Trial: A randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery. Am J Heart 2006; 152: 223-30
13. POISE Study Group. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): A randomised controlled trial. Lancet 2008; 371: 1839-47
14. Williamson E, Morley R, Lucas A, Carpenter J. Propensity scores: From nai?ve enthusiasm to intuitive understanding. Stat Methods Med Res 2012; 21: 273-93
15. Rosenbaum P, Rubin D. The central role of the propensity score in observational studies for causal effects. Biometrika 1983; 70: 41-55
16. Austin P, Grootendorst P, Anderson G. A comparison of the ability of different propensity score models to balance measured variables between treated and untreated subjects: A Monte Carlo study. Stat Med 2007; 26: 734-53
17. Sharon-Lise T, Normand S-LT, Landruma M, et al. Validating recommendations for coronary angiography following acute myocardial infarction in the elderly: A matched analysis using propensity scores. J Clin Epi 2001; 54: 387-98
18. Monk T, Saini V, Weldon B, Sigl J. Anesthetic management and one-year mortality after noncardiac surgery. Anesth Analg 2005; 100: 4-10
19. Leslie K, Myles P, Forbes A, Chan M. The effect of bispectral index monitoring on long-Term survival in the B-Aware trial. Anesth Analg 2010; 110: 816-22
20. Holte K, Sharrock N, Kehlet H. Pathophysiology and clinical implications of perioperative fluid excess. Br J Anaesth 2002; 89: 622-32
21. Carli F, Stricker T. Modification of metabolic response to surgery by neural blockade. In: Cousins M, Carr D, Horlocker T, Bridenbaugh P, eds. Neural Blockade in Clinical Anaesthesia and Pain Management. Philadelphia: Wolters Kluwer/Lippincott Wilkins & Williams, 2009; 133-44
22. Stone J, Foex P, Sear J, et al. Risk of myocardial ischaemia during anaesthesia in treated and untreated hypertensive patients. Br J Anaesth 1988; 61: 675-9
23. Wallace A, Layug B, Tateo I, et al. Prophylactic atenolol reduces postoperative myocardial ischemia. Anesthesiology 1998; 88: 7-17
24. Schouten O, Bax J, Dunkelgrun M, Feringa H, Poldermans D. Pro: Beta-blockers are indicated for patients at risk for cardiac complications undergoing noncardiac surgery. Anesth Analg 2007; 104: 8-10
25. Wijeysundera D, Beattie W, Austin P, Hux J, Laupacis A. Epidural anaesthesia and survival after intermediate-To-high risk noncardiac surgery: A population-based cohort study. Lancet 2008; 372: 562-9
26. Welke K, Diggs B, Karamlou T, Ungerleider R. Comparison of pediatric cardiac surgical mortality rates from national administrative data to contemporary clinical standards. Ann Thorac Surg 2009; 87: 216-22
27. Vlasschaert M, Bejaimal S, Hackam D, et al. Validity of administrative database coding for kidney disease: A systematic review. Am J Kidney Dis 2011; 57: 29-43
28. Werrett G, Horton H, Craig R, French R. The use of epidural analgesia in a New Zealand tertiary hospital before and after publication of the MASTER study. Anaesth Intensive Care 2008; 36: 79-83
29. Bode R, Lewis K, Zarich S, et al. Cardiac outcomes after peripheral vascular surgery. Anesthesiology 1996; 84: 3-13