Disruption of canonical TGFβ-signaling in murine coronary progenitor cells by low level arsenic

Toxicology and Applied Pharmacology

Volumn 272, Issue 1, 2013, Pages 147-153

  Allison, Patrick ^a   Huang, Tianfang ^a   Broka, Derrick ^a   Parker, Patti ^a   Barnett, Joey V ^b   Camenisch, Todd D ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Arsenic; Epicardial cells; Epithelial to mesenchymal transition; TGF beta

Indexed keywords

ARSENIC; ARSENIC TRIOXIDE; ARSENITE SODIUM; MESSENGER RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; VIMENTIN;

ACUTE TOXICITY; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CORONARY BLOOD VESSEL; DOWN REGULATION; EPICARDIUM; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HEART MUSCLE CELL; IN VITRO STUDY; MESENCHYME; MESENCHYME CELL; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; STEM CELL; WESTERN BLOTTING;

ARSENIC; EPICARDIAL CELLS; EPITHELIAL TO MESENCHYMAL TRANSITION; TGF-BETA;

ANIMALS; ARSENITES; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CORONARY VESSELS; EPITHELIAL-MESENCHYMAL TRANSITION; FLUORESCENT ANTIBODY TECHNIQUE; INDICATORS AND REAGENTS; MESENCHYMAL STROMAL CELLS; MICE; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MYOCYTES, SMOOTH MUSCLE; SIGNAL TRANSDUCTION; SMAD PROTEINS; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84882767326     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.04.035     Document Type: Article

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