Enhancing the solubility of fluconazole using a new essential oil based microemulsion system

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue SUPPL 3, 2013, Pages 697-699

  Nirmala, M Joyce ^a   Allanki, Srinivas ^a   Mukherjee, Amitava ^a   Chandrasekaran, N ^a  

^a VIT UNIVERSITY   (India)

Author keywords

Cinnamon oil; Drug delivery system; Fluconazole; Microemulsion; Solubility

Indexed keywords

ESSENTIAL OIL; FLUCONAZOLE;

ARTICLE; CINNAMON; CONDUCTANCE; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG STABILITY; HYDRODYNAMICS; MICROEMULSION; PARTICLE SIZE; VISCOSITY;

EID: 84882741639     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Sheehan D, Hitchcock C and Sibley C. Current and Emerging Azole Antifungal Agents. Clin Microbiol Rev. 1999; 12: 40-79.
2. Nucci M and Marr KA. Emerging Fungal Diseases. Clin Infect Dis. 2005; 4: 521-6.
3. Rex JH, Rinaldi MG and Pfaller MA. Resistance of Candida species to fluconazole. Antimicrob Agents Chemother. 1995; 39: 1-8.
4. Brammer KW, Farrow PR and Faulkner JK. Pharmacokinetics and Tissue Penetration of Fluconazole in Humans. Clin Infect Dis. 1990; 12: 318-326.
5. Lawrencea MJ and Reesb GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Deliver Rev. 2000; 45: 89-121.
6. Nirmala G, Padmini R and Rashmi M. Microemulsions For Topical Use-A Review. Ind J Pharm Edu Res. 2011; 45: 103-110.
7. Nirmala MJ, Mukherjee A and Chandrasekaran N. Improved efficacy of fluconazole against candidiasis using bio-based microemulsion technique. Biotechnol Appl Bioc. 2013; 00: 01-13.
8. Vijayalakshmi G, Mukherjee A and Chandrasekaran N. Mustard Oil Microemulsion Formulation and Evaluation of Bactericidal Activity. Int J Pharm Pharm Sci. 2012; 4: 497-500.
9. Sonia K, Anupama D. Microemulsion based Transdermal Drug delivery of Tea Tree Oil. Int. J. Drug Dev & Res. 2011; 3: 191-198.
10. Shinoda K and Saito H. The Stability of O/W Type Emulsions as Functions of Temperature and the HLB of Emulsifiers: The Emulsification by PIT-method. J. Colloid Interface Sci. 1969; 30: 258-263.
11. Singh HB, Srivastava M, Singh AB and Srivastava AK. Cinnamon bark oil, a potent fungitoxicant against fungi causing respiratory tract mycoses. Allergy. 1995; 12: 995-999.