메뉴 건너뛰기




Volumn 6, Issue SUPPL.1, 2013, Pages 9-14

Determination of l-tryptophan and L-kynurenine in human serum by using LC-MS after derivatization with (R)-DBD-PyNCS

Author keywords

(R) ( ) 4 (N, N dimethylaminosulfonyl) 7 (3 isothiocyanatopyrrolidin 1 yl) 2,1,3 benzoxadiazole (DBD PyNCS); High performance liquid chromatography; Human serum; L kynurenine; L tryptophan; Mass spectrometry

Indexed keywords


EID: 84882724081     PISSN: None     EISSN: 11786469     Source Type: Journal    
DOI: 10.4137/IJTR.S11459     Document Type: Article
Times cited : (25)

References (23)
  • 1
  • 2
    • 33645214553 scopus 로고    scopus 로고
    • Tryptophan metabolism and oxidative stress in patients with chronic brain injury
    • Mackay GM, Forrest CM, Stoy N, et al. Tryptophan metabolism and oxidative stress in patients with chronic brain injury. Eur J Neurol. 2006;13(1): 30-42.
    • (2006) Eur J Neurol. , vol.13 , Issue.1 , pp. 30-42
    • Mackay, G.M.1    Forrest, C.M.2    Stoy, N.3
  • 3
    • 0031900585 scopus 로고    scopus 로고
    • Serum kynurenine-to-tryptophan ratio increases with progressive disease in HIV-infected patients
    • Huengsberg M, Winer JB, Gompels M, Round R, Ross J, Shahmanesh M. Serum kynurenine-to-tryptophan ratio increases with progressive disease in HIV-infected patients. Clin Chem. 1998;44(4):858-62.
    • (1998) Clin Chem. , vol.44 , Issue.4 , pp. 858-862
    • Huengsberg, M.1    Winer, J.B.2    Gompels, M.3    Round, R.4    Ross, J.5    Shahmanesh, M.6
  • 4
    • 0028265462 scopus 로고
    • Role of serotonin in the pathophysiology of depression-focus on the serotonin transporter
    • Owens MJ, Nemeroff CB. Role of serotonin in the pathophysiology of depression-focus on the serotonin transporter. Clin Chem. 1994;40(2):288-95.
    • (1994) Clin Chem. , vol.40 , Issue.2 , pp. 288-295
    • Owens, M.J.1    Nemeroff, C.B.2
  • 5
    • 84859435674 scopus 로고    scopus 로고
    • Simultaneous determination of tyrosine, tryptophan and 5-hydroxytryptamine in serum of MDD patients by high performance liquid chromatography with fluorescence detection
    • Mu S, Li Y, Tang AG, Xiao LD, Ren YP. Simultaneous determination of tyrosine, tryptophan and 5-hydroxytryptamine in serum of MDD patients by high performance liquid chromatography with fluorescence detection. Clin Chim Acta. 2012;413(11-2):973-7.
    • (2012) Clin Chim Acta. , vol.413 , Issue.11-12 , pp. 973-977
    • Mu, S.1    Li, Y.2    Tang, A.G.3    Xiao, L.D.4    Ren, Y.P.5
  • 6
    • 0026044893 scopus 로고
    • Tryptophan nutrition and metabolism: an overview
    • Peters JC. Tryptophan nutrition and metabolism: an overview. Adv Exp Med Biol. 1991;294:345-58.
    • (1991) Adv Exp Med Biol. , vol.294 , pp. 345-358
    • Peters, J.C.1
  • 8
    • 84859739642 scopus 로고    scopus 로고
    • Modulation of tryptophan metabolism, promotion of neurogenesis and alteration of anxiety-related behavior in tryptophan 2,3-dioxygenase-deficient mice
    • Funakoshi H, Kanai M, Nakamura T. Modulation of tryptophan metabolism, promotion of neurogenesis and alteration of anxiety-related behavior in tryptophan 2,3-dioxygenase-deficient mice. Int J Tryptophan Res. 2011;4: 7-18.
    • (2011) Int J Tryptophan Res. , vol.4 , pp. 7-18
    • Funakoshi, H.1    Kanai, M.2    Nakamura, T.3
  • 9
    • 67650721438 scopus 로고    scopus 로고
    • Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2, 3-dioxygenase (IDO), a novel target in cancer disease
    • Macchiarulo A, Camaioni E, Nuti R, Pellicciari R. Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2, 3-dioxygenase (IDO), a novel target in cancer disease. Amino Acids. 2009;37(2):219-29.
    • (2009) Amino Acids. , vol.37 , Issue.2 , pp. 219-229
    • Macchiarulo, A.1    Camaioni, E.2    Nuti, R.3    Pellicciari, R.4
  • 10
    • 84864772397 scopus 로고    scopus 로고
    • Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression
    • Kim H, Chen L, Lim G, et al. Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J Clin Invest. 2012;122(8): 2940-54.
    • (2012) J Clin Invest. , vol.122 , Issue.8 , pp. 2940-2954
    • Kim, H.1    Chen, L.2    Lim, G.3
  • 11
    • 69149084827 scopus 로고    scopus 로고
    • Manipulation of indoleamine 2,3 dioxygenase; a novel therapeutic target for treatment of diseases
    • Tan PH, Bharath AK. Manipulation of indoleamine 2,3 dioxygenase; a novel therapeutic target for treatment of diseases. Expert Opin Therapeutic Targets. 2009;13(8):987-1012.
    • (2009) Expert Opin Therapeutic Targets. , vol.13 , Issue.8 , pp. 987-1012
    • Tan, P.H.1    Bharath, A.K.2
  • 12
    • 65549110631 scopus 로고    scopus 로고
    • Simultaneous determination of tryptophan and kynurenine in plasma samples of children patients with Kawasaki disease by high-performance liquid chromatography with programmed wavelength ultraviolet detection
    • Zhang XQ, He Y, Ding M. Simultaneous determination of tryptophan and kynurenine in plasma samples of children patients with Kawasaki disease by high-performance liquid chromatography with programmed wavelength ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(16-7):1678-82.
    • (2009) J Chromatogr B Analyt Technol Biomed Life Sci. , vol.877 , Issue.16-17 , pp. 1678-1682
    • Zhang, X.Q.1    He, Y.2    Ding, M.3
  • 13
    • 75349102657 scopus 로고    scopus 로고
    • Optimization of Zn2+-containing mobile phase for simultaneous determination of kynurenine, kynurenic acid and tryptophan in human plasma by high performance liquid chromatography
    • Zhao JX, Gao PJ, Zhu DL. Optimization of Zn2+-containing mobile phase for simultaneous determination of kynurenine, kynurenic acid and tryptophan in human plasma by high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878(5-6):603-8.
    • (2010) J Chromatogr B Analyt Technol Biomed Life Sci. , vol.878 , Issue.5-6 , pp. 603-608
    • Zhao, J.X.1    Gao, P.J.2    Zhu, D.L.3
  • 14
    • 79959933891 scopus 로고    scopus 로고
    • Determination of tryptophan and kynurenine in human plasma by liquid chromatography-electrochemical detection with multi-wall carbon nanotube-modified glassy carbon electrode
    • Liu LH, Chen Y, Zhang YL, Wang F, Chen ZL. Determination of tryptophan and kynurenine in human plasma by liquid chromatography-electrochemical detection with multi-wall carbon nanotube-modified glassy carbon electrode. Biomed Chromatogr. 2011;25(8):938-42.
    • (2011) Biomed Chromatogr. , vol.25 , Issue.8 , pp. 938-942
    • Liu, L.H.1    Chen, Y.2    Zhang, Y.L.3    Wang, F.4    Chen, Z.L.5
  • 15
    • 42749093500 scopus 로고    scopus 로고
    • Simultaneous measurement of tryptophan and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry
    • Yamada K, Miyazaki T, Shibata T, Hara N, Tsuchiya M. Simultaneous measurement of tryptophan and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2008;867(1):57-61.
    • (2008) J Chromatogr B Analyt Technol Biomed Life Sci. , vol.867 , Issue.1 , pp. 57-61
    • Yamada, K.1    Miyazaki, T.2    Shibata, T.3    Hara, N.4    Tsuchiya, M.5
  • 16
    • 60449106709 scopus 로고    scopus 로고
    • Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry
    • de Jong WH, Smit R, Bakker SJ, de Vries EG, Kema IP. Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(7):603-9.
    • (2009) J Chromatogr B Analyt Technol Biomed Life Sci. , vol.877 , Issue.7 , pp. 603-609
    • de Jong, W.H.1    Smit, R.2    Bakker, S.J.3    de Vries, E.G.4    Kema, I.P.5
  • 17
    • 82555179297 scopus 로고    scopus 로고
    • Fluorescence determination of d- and l-tryptophan concentrations in rat plasma following administration of tryptophan enantiomers using HPLC with pre-column derivatization
    • Iizuka H, Ishii K, Hirasa Y, Kubo K, Fukushima T. Fluorescence determination of d- and l-tryptophan concentrations in rat plasma following administration of tryptophan enantiomers using HPLC with pre-column derivatization. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879(29):3208-13.
    • (2011) J Chromatogr B Analyt Technol Biomed Life Sci. , vol.879 , Issue.29 , pp. 3208-3213
    • Iizuka, H.1    Ishii, K.2    Hirasa, Y.3    Kubo, K.4    Fukushima, T.5
  • 18
    • 0031714935 scopus 로고    scopus 로고
    • Total resolution of 17 DL-amino acids labeled with a fluorescent chiral reagent, R(-)-4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole, by high-performance liquid chromatography
    • Jin DR, Nagakura K, Murofushi S, Miyahara T, Toyo'oka T. Total resolution of 17 DL-amino acids labeled with a fluorescent chiral reagent, R(-)-4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole, by high-performance liquid chromatography. J Chromatogr A. 1998;822(2):215-24.
    • (1998) J Chromatogr A. , vol.822 , Issue.2 , pp. 215-224
    • Jin, D.R.1    Nagakura, K.2    Murofushi, S.3    Miyahara, T.4    Toyo'oka, T.5
  • 19
    • 42549134495 scopus 로고    scopus 로고
    • Recent progress in the development of derivatization reagents having a benzofurazan structure
    • Santa T, Fukushima T, Ichibangase T, Imai K. Recent progress in the development of derivatization reagents having a benzofurazan structure. Biomed Chromatogr. 2008;22(4):343-53.
    • (2008) Biomed Chromatogr. , vol.22 , Issue.4 , pp. 343-353
    • Santa, T.1    Fukushima, T.2    Ichibangase, T.3    Imai, K.4
  • 20
    • 65249173106 scopus 로고    scopus 로고
    • Derivatization reagents in liquid chromatography/electrospray ionization tandem mass spectrometry for biomedical analysis
    • Santa T, Al-Dirbashi OY, Fukushima T. Derivatization reagents in liquid chromatography/electrospray ionization tandem mass spectrometry for biomedical analysis. Drug Discov Ther. 2007;1(2):108-18.
    • (2007) Drug Discov Ther. , vol.1 , Issue.2 , pp. 108-118
    • Santa, T.1    Al-Dirbashi, O.Y.2    Fukushima, T.3
  • 21
    • 79958221133 scopus 로고    scopus 로고
    • Enantiomeric separation of D, l-tryptophan and d, l-kynurenine by HPLC using pre-column fluorescence derivatization with R(-)-DBD-PyNCS
    • Iizuka H, Hirasa Y, Kubo K, Ishii K, Toyo'oka T, Fukushima T. Enantiomeric separation of D, l-tryptophan and d, l-kynurenine by HPLC using pre-column fluorescence derivatization with R(-)-DBD-PyNCS. Biomed Chromatogr. 2011;25(7):743-7.
    • (2011) Biomed Chromatogr. , vol.25 , Issue.7 , pp. 743-747
    • Iizuka, H.1    Hirasa, Y.2    Kubo, K.3    Ishii, K.4    Toyo'oka, T.5    Fukushima, T.6
  • 23
    • 65449120384 scopus 로고    scopus 로고
    • Cytokine changes and tryptophan metabolites in medication-naive and medication-free schizophrenic patients
    • Kim YK, Myint AM, Verkerk R, Scharpe S, Steinbusch H, Leonard B. Cytokine changes and tryptophan metabolites in medication-naive and medication-free schizophrenic patients. Neuropsychobiology. 2009;59(2): 123-9.
    • (2009) Neuropsychobiology. , vol.59 , Issue.2 , pp. 123-129
    • Kim, Y.K.1    Myint, A.M.2    Verkerk, R.3    Scharpe, S.4    Steinbusch, H.5    Leonard, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.