Overexpression of adenylate cyclase-associated protein 1 is associated with metastasis of lung cancer

Oncology Reports

Volumn 30, Issue 4, 2013, Pages 1639-1644

  Tan, Min ^a   Song, Xiaolian ^a   Zhang, Guoliang ^a   Peng, Aimei ^a   Li, Xuan ^a   Li, Ming ^a   Liu, Yang ^a   Wang, Changhui ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

Adenylate cyclase associated protein; Cyclase associated protein 1; Lung cancer; Metastasis; Small interfering RNA

Indexed keywords

ACTIN BINDING PROTEIN; ADENYLATE CYCLASE ASSOCIATED PROTEIN 1; MESSENGER RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER CLASSIFICATION; CANCER STAGING; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISTANT METASTASIS; DRUG EFFECT; FEMALE; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG ADENOCARCINOMA; LUNG BIOPSY; LUNG CANCER; LUNG SQUAMOUS CELL CARCINOMA; LYMPH NODE METASTASIS; MALE; METASTASIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN CONTENT; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR INVASION; WESTERN BLOTTING;

ADENOCARCINOMA; AGED; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; CYTOSKELETAL PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROGNOSIS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84882615537     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2607     Document Type: Article

References (18)

1. Chang S, Dai M, Ren JS, Chen YH and Guo LW: Estimates and prediction on incidence, mortality and prevalence of lung cancer in China in 2008. Zhonghua Liu Xing Bing Xue Za Zhi 33: 391-394, 2012 (In Chinese).
2. Ramalingam SS, Owonikoko TK and Khuri FR: Lung cancer: new biological insights and recent therapeutic advances. CA Cancer J Clin 61: 91-112, 2011.
3. Cho JY and Sung HJ: Proteomic approaches in lung cancer biomarker development. Expert Rev Proteomics 6: 27-42, 2009.
4. Valle RP, Chavany C, Zhukov TA and Jendoubi M: New approaches for biomarker discovery in lung cancer. Expert Rev Mol Diagn 3: 55-67, 2003.
5. Fedor-Chaiken M, Deschenes RJ and Broach JR: SRV2, a gene required for RAS activation of adenylate cyclase in yeast. Cell 61: 329-340, 1990.
6. Field J, Vojtek A, Ballester R, et al: Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein. Cell 61: 319-327, 1990.
7. Matviw H, Yu G and Young D: Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins. Mol Cell Biol 12: 5033-5040, 1992.
8. Freeman NL, Chen Z, Horenstein J, Weber A and Field J: An actin monomer binding activity localizes to the carboxyl-terminal half of the Saccharomyces cerevisiae cyclase-associated protein. J Biol Chem 270: 5680-5685, 1995.
9. Moriyama K and Yahara I: Human CAP1 is a key factor in the recycling of cofilin and actin for rapid actin turnover. J Cell Sci 115: 1591-1601, 2002.
10. Hubberstey AV and Mottillo EP: Cyclase-associated proteins: CAPacity for linking signal transduction and actin polymerization. FASEB J 16: 487-499, 2002.
11. Loisel TP, Boujemaa R, Pantaloni D and Carlier MF: Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature 401: 613-616, 1999.
12. Yamazaki K, Takamura M, Masugi Y, et al: Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility. Lab Invest 89: 425-432, 2009.
13. Chen G, Gharib TG, Huang CC, et al: Discordant protein and mRNA expression in lung adenocarcinomas. Mol Cell Proteomics 1: 304-313, 2002.
14. Renyi-Vamos F, Tovari J, Fillinger J, et al: Lymphangiogenesis correlates with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer. Clin Cancer Res 11: 7344-7353, 2005.
15. Sun JG, Wang Y, Chen ZT, et al: Detection of lymphangiogenesis in non-small cell lung cancer and its prognostic value. J Exp Clin Cancer Res 28: 21, 2009.
16. Macrae IJ, Zhou K, Li F, et al: Structural basis for double-stranded RNA processing by Dicer. Science 311: 195-198, 2006.
17. Van Troys M, Huyck L, Leyman S, Dhaese S, Vandekerkhove J and Ampe C: Ins and outs of ADF/cofilin activity and regulation. Eur J Cell Biol 87: 649-667, 2008.
18. Wang W, Eddy R and Condeelis J: The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer 7: 429-440, 2007.