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Volumn 90, Issue 10, 2012, Pages 3337-3352

Transcriptomic analysis identifies candidate genes and functional networks controlling the response of porcine peripheral blood mononuclear cells to mitogenic stimulation

Author keywords

Concanavalin a; Microarray; Pathway analysis; Peripheral blood mononuclear cells; Pig

Indexed keywords

CONCANAVALIN A; MESSENGER RNA; MITOGENIC AGENT; TRANSCRIPTOME;

EID: 84882613778     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2012-5167     Document Type: Article
Times cited : (7)

References (62)
  • 1
    • 45149084830 scopus 로고    scopus 로고
    • TULA proteins regulate activity of the protein tyrosine kinase syk
    • Agrawal, R., N. Carpino, and A. Tsygankov. 2008. TULA proteins regulate activity of the protein tyrosine kinase syk. J. Cell. Biochem. 104:953-964.
    • (2008) J. Cell. Biochem. , vol.104 , pp. 953-964
    • Agrawal, R.1    Carpino, N.2    Tsygankov, A.3
  • 3
    • 33744832043 scopus 로고    scopus 로고
    • Functional characterization of the calcipressin 1 motif that suppresses cal-cineurin-mediated NFAT-dependent cytokine gene expression in human T cells
    • Aubareda, A., M. C. Mulero, and M. Perez-Riba. 2006. Functional characterization of the calcipressin 1 motif that suppresses cal-cineurin-mediated NFAT-dependent cytokine gene expression in human T cells. Cell. Signal 18:1430-1438.
    • (2006) Cell. Signal. , vol.18 , pp. 1430-1438
    • Aubareda, A.1    Mulero, M.C.2    Perez-Riba, M.3
  • 4
    • 0018286485 scopus 로고
    • Human lympho-cyte cell cycle: Studies with the use of BrUdR
    • Auf der Maur, P., and K. Berlincourt-Bohni. 1979. Human lympho-cyte cell cycle: Studies with the use of BrUdR. Hum. Genet. 49:209-215.
    • (1979) Hum. Genet. , vol.49 , pp. 209-215
    • Auf der Maur, P.1    Berlincourt-Bohni, K.2
  • 5
    • 33847236576 scopus 로고    scopus 로고
    • The bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage
    • Babbe, H., N. Chester, P. Leder, and B. Reizis. 2007. The bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage. Mol. Cell. Biol. 27:1947-1959.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 1947-1959
    • Babbe, H.1    Chester, N.2    Leder, P.3    Reizis, B.4
  • 7
    • 0028363377 scopus 로고
    • The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
    • Bamford, R. N., A. J. Grant, J. D. Burton, C. Peters, G. Kurys, C. K. Goldman, J. Brennan, E. Roessler, and T. A. Waldmann. 1994. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc. Natl. Acad. Sci. USA 91:4940-4944.
    • (1994) Proc. Natl. Acad. Sci. USA. , vol.91 , pp. 4940-4944
    • Bamford, R.N.1    Grant, A.J.2    Burton, J.D.3    Peters, C.4    Kurys, G.5    Goldman, C.K.6    Brennan, J.7    Roessler, E.8    Waldmann, T.A.9
  • 8
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for pro-liferative renewal of virus-specific memory CD8 T cells
    • Becker, T. C., E. J. Wherry, D. Boone, K. Murali-Krishna, R. Antia, A. Ma, and R. Ahmed. 2002. Interleukin 15 is required for pro-liferative renewal of virus-specific memory CD8 T cells. J. Exp. Med. 195:1541-1548.
    • (2002) J. Exp. Med. , vol.195 , pp. 1541-1548
    • Becker, T.C.1    Wherry, E.J.2    Boone, D.3    Murali-Krishna, K.4    Antia, R.5    Ma, A.6    Ahmed, R.7
  • 9
    • 0001677717 scopus 로고
    • Controlling the false discov-ery rate: A practical and powerful approach for multiple testing
    • Benjamini, Y., and Y. Hochberg. 1995. Controlling the false discov-ery rate: A practical and powerful approach for multiple testing. J. Royal Statistical Soc. Series B. Methodological 57:289-300.
    • (1995) J. Royal Statistical Soc. Series B. Methodological , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 10
    • 0023572209 scopus 로고
    • Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of tran-scription factor AP-1
    • Bohmann, D., T. J. Bos, A. Admon, T. Nishimura, P. K. Vogt, and R. Tjian. 1987. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of tran-scription factor AP-1. Science 238:1386-1392.
    • (1987) Science , vol.238 , pp. 1386-1392
    • Bohmann, D.1    Bos, T.J.2    Admon, A.3    Nishimura, T.4    Vogt, P.K.5    Tjian, R.6
  • 12
    • 0037144408 scopus 로고    scopus 로고
    • Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions
    • Bower, K. E., R. W. Zeller, W. Wachsman, T. Martinez, and K. L. McGuire. 2002. Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions. J. Biol. Chem. 277:34967-34977.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34967-34977
    • Bower, K.E.1    Zeller, R.W.2    Wachsman, W.3    Martinez, T.4    McGuire, K.L.5
  • 14
    • 0031018766 scopus 로고    scopus 로고
    • NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor
    • Brooks, A. G., P. E. Posch, C. J. Scorzelli, F. Borrego, and J. E. Coligan. 1997. NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J. Exp. Med. 185:795-800.
    • (1997) J. Exp. Med. , vol.185 , pp. 795-800
    • Brooks, A.G.1    Posch, P.E.2    Scorzelli, C.J.3    Borrego, F.4    Coligan, J.E.5
  • 16
    • 50849133574 scopus 로고    scopus 로고
    • Signalling, inflam-mation and arthritis: Crossed signals: The role of interleukin-15 and-18 in autoimmunity
    • Carroll, H. P., V. Paunovic, and M. Gadina. 2008. Signalling, inflam-mation and arthritis: Crossed signals: The role of interleukin-15 and-18 in autoimmunity. Rheumatology. Oxford 47:1269-1277.
    • (2008) Rheumatology. Oxford , vol.47 , pp. 1269-1277
    • Carroll, H.P.1    Paunovic, V.2    Gadina, M.3
  • 17
    • 63049118828 scopus 로고    scopus 로고
    • Understanding haemophilus parasuis infection in porcine spleen through a transcriptomics approach
    • Chen, H., C. Li, M. Fang, M. Zhu, X. Li, R. Zhou et al. 2009. Understanding haemophilus parasuis infection in porcine spleen through a transcriptomics approach. BMC Genomics 10:64.
    • (2009) BMC Genomics , vol.10 , pp. 64
    • Chen, H.1    Li, C.2    Fang, M.3    Zhu, M.4    Li, X.5    Zhou, R.6
  • 18
    • 19244369810 scopus 로고    scopus 로고
    • Adaptor function for the syk kinases-interacting protein 3BP2 in IL-2 gene activation
    • Deckert, M., S. Tartare-Deckert, J. Hernandez, R. Rottapel, and A. Altman. 1998. Adaptor function for the syk kinases-interacting protein 3BP2 in IL-2 gene activation. Immunity 9:595-605.
    • (1998) Immunity , vol.9 , pp. 595-605
    • Deckert, M.1    Tartare-Deckert, S.2    Hernandez, J.3    Rottapel, R.4    Altman, A.5
  • 21
    • 0025788983 scopus 로고
    • Genetic variation in con A-induced production of interleukin 2 by porcine peripheral blood mononuclear cells
    • Edfors-Lilja, I., M. Bergstrom, U. Gustafsson, U. Magnusson, and C. Fossum. 1991. Genetic variation in con A-induced production of interleukin 2 by porcine peripheral blood mononuclear cells. Vet. Immunol. Immunopathol. 27:351-363.
    • (1991) Vet. Immunol. Immunopathol. , vol.27 , pp. 351-363
    • Edfors-Lilja, I.1    Bergstrom, M.2    Gustafsson, U.3    Magnusson, U.4    Fossum, C.5
  • 22
    • 0342758487 scopus 로고    scopus 로고
    • Mapping quantitative trait loci for stress induced alterations in porcine leukocyte numbers and functions
    • Edfors-Lilja, I., E. Wattrang, L. Andersson, and C. Fossum. 2000. Mapping quantitative trait loci for stress induced alterations in porcine leukocyte numbers and functions. Anim. Genet. 31:186-193.
    • (2000) Anim. Genet. , vol.31 , pp. 186-193
    • Edfors-Lilja, I.1    Wattrang, E.2    Andersson, L.3    Fossum, C.4
  • 24
    • 0025871394 scopus 로고
    • Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A
    • Flanagan, W. M., B. Corthesy, R. J. Bram, and G. R. Crabtree. 1991. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 352:803-807.
    • (1991) Nature , vol.352 , pp. 803-807
    • Flanagan, W.M.1    Corthesy, B.2    Bram, R.J.3    Crabtree, G.R.4
  • 27
    • 0842343437 scopus 로고    scopus 로고
    • Activation/division of lym-phocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: Prototype of a new family of proteins
    • Grill, B., G. M. Wilson, K. X. Zhang, B. Wang, R. Doyonnas, M. Quadroni, and J. W. Schrader. 2004. Activation/division of lym-phocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: Prototype of a new family of proteins. J. Immunol. 172:2389-2400.
    • (2004) J. Immunol , vol.172 , pp. 2389-2400
    • Grill, B.1    Wilson, G.M.2    Zhang, K.X.3    Wang, B.4    Doyonnas, R.5    Quadroni, M.6    Schrader, J.W.7
  • 29
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioin-formatics resources
    • Huang da, W., B. T. Sherman, and R. A. Lempicki. 2009. Systematic and integrative analysis of large gene lists using DAVID bioin-formatics resources. Nat. Protoc. 4:44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 30
    • 0034662261 scopus 로고    scopus 로고
    • Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein
    • Iacobelli, M., W. Wachsman, and K. L. McGuire. 2000. Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein. J. Immunol. 165:860-868.
    • (2000) J. Immunol. , vol.165 , pp. 860-868
    • Iacobelli, M.1    Wachsman, W.2    McGuire, K.L.3
  • 31
    • 0027491776 scopus 로고
    • The T-cell transcrip-tion factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
    • Jain, J., P. G. McCaffrey, Z. Miner, T. K. Kerppola, J. N. Lambert, G. L. Verdine, T. Curran, and A. Rao. 1993a. The T-cell transcrip-tion factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365:352-355.
    • (1993) Nature , vol.365 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, Z.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curran, T.7    Rao, A.8
  • 32
    • 0027491776 scopus 로고
    • The T-cell transcrip-tion factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
    • Jain, J., P. G. McCaffrey, Z. Miner, T. K. Kerppola, J. N. Lambert, G. L. Verdine T. Curran, and A. Rao.1993b. The T-cell transcrip-tion factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365:352-355.
    • (1993) Nature , vol.365 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, Z.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curran, T.7    Rao, A.8
  • 33
    • 0028088479 scopus 로고
    • Cloning and expression of cyclosporin A-and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90
    • Kao, P. N., L. Chen, G. Brock, J. Ng, J. Kenny, A. J. Smith, and B. Corthésy. 1994. Cloning and expression of cyclosporin A-and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90. J. Biol. Chem. 269:20691-20699.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20691-20699
    • Kao, P.N.1    Chen, L.2    Brock, G.3    Ng, J.4    Kenny, J.5    Smith, A.J.6    Corthésy, B.7
  • 34
    • 0031881906 scopus 로고    scopus 로고
    • Human 4-1BB regulates CD28 co-stimulation to promote Th1 cell re-sponses
    • Kim, Y. J., S. H. Kim, P. Mantel, and B. S. Kwon. 1998. Human 4-1BB regulates CD28 co-stimulation to promote Th1 cell re-sponses. Eur. J. Immunol. 28:881-890.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 881-890
    • Kim, Y.J.1    Kim, S.H.2    Mantel, P.3    Kwon, B.S.4
  • 37
    • 35348909203 scopus 로고    scopus 로고
    • Genetic perspectives on host responses to por-cine reproductive and respiratory syndrome (PRRS)
    • Lewis, C. R., T. Ait-Ali, M. Clapperton, A. L. Archibald, and S. Bishop. 2007. Genetic perspectives on host responses to por-cine reproductive and respiratory syndrome (PRRS). Viral Immunol. 20:343-358.
    • (2007) Viral Immunol , vol.20 , pp. 343-358
    • Lewis, C.R.1    Ait-Ali, T.2    Clapperton, M.3    Archibald, A.L.4    Bishop, S.5
  • 39
    • 76249103099 scopus 로고    scopus 로고
    • Early growth response protein-1 (egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is in-volved in acute transcription of the Th2 cytokine interleukin-4
    • Lohoff, M., M. Giaisi, R. Kohler, B. Casper, P. H. Krammer, and M. Li-Weber. 2010. Early growth response protein-1 (egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is in-volved in acute transcription of the Th2 cytokine interleukin-4. J. Biol. Chem. 285:1643-1652.
    • (2010) J. Biol. Chem. , vol.285 , pp. 1643-1652
    • Lohoff, M.1    Giaisi, M.2    Kohler, R.3    Casper, B.4    Krammer, P.H.5    Li-Weber, M.6
  • 41
    • 0000484021 scopus 로고
    • Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ ef-fector T cells recognize products of different major histo-compatibility complex regions
    • Meuer, S. C., S. F. Schlossman, and E. L. Reinherz. 1982. Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ ef-fector T cells recognize products of different major histo-compatibility complex regions. Proc. Natl. Acad. Sci. USA 79:4395-4399.
    • (1982) Proc. Natl. Acad. Sci. USA. , vol.79 , pp. 4395-4399
    • Meuer, S.C.1    Schlossman, S.F.2    Reinherz, E.L.3
  • 43
    • 0029117434 scopus 로고
    • Ligation of the T-cell antigen receptor (TCR) induces associa-tion of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR
    • Nel, A. E., S. Gupta, L. Lee, J. A. Ledbetter, and S. B. Kanner. 1995. Ligation of the T-cell antigen receptor (TCR) induces associa-tion of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR. J. Biol. Chem. 270:18428-18436.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18428-18436
    • Nel, A.E.1    Gupta, S.2    Lee, L.3    Ledbetter, J.A.4    Kanner, S.B.5
  • 44
    • 0020076244 scopus 로고
    • Concanavalin A triggers T lymphocytes by di-rectly interacting with their receptors for activation
    • Palacios, R. 1982. Concanavalin A triggers T lymphocytes by di-rectly interacting with their receptors for activation. J. Immunol. 128: 337-342.
    • (1982) J. Immunol. , vol.128 , pp. 337-342
    • Palacios, R.1
  • 45
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantifi-cation in real-time RT-PCR
    • Pfaffl, M. W. 2001. A new mathematical model for relative quantifi-cation in real-time RT-PCR. Nucleic Acids Res. 29:e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 46
    • 0036581160 scopus 로고    scopus 로고
    • Relative expres-sion software tool (REST) for group-wise comparison and sta-tistical analysis of relative expression results in real-time PCR
    • Pfaffl, M. W., G. W. Horgan, and L. Dempfle. 2002. Relative expres-sion software tool (REST) for group-wise comparison and sta-tistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30:e36.
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 48
    • 0035254238 scopus 로고    scopus 로고
    • Interferon-inducible protein 10, monokine induced by interferon gamma, and inter-feron-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabe-ta+ CD8+ single-positive T cells, TCRgammadelta+ T cells, and natural killer-type cells in human thymus
    • Romagnani, P., F. Annunziato, E. Lazzeri, L. Cosmi, C. Beltrame, L. Lasagni, G. Galli, M. Francalanci, R. Manetti, F. Marra, V. Vanini, E. Maggi, and S. Romagnani. 2001. Interferon-inducible protein 10, monokine induced by interferon gamma, and inter-feron-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabe-ta+ CD8+ single-positive T cells, TCRgammadelta+ T cells, and natural killer-type cells in human thymus. Blood 97:601-607.
    • (2001) Blood , vol.97 , pp. 601-607
    • Romagnani, P.1    Annunziato, F.2    Lazzeri, E.3    Cosmi, L.4    Beltrame, C.5    Lasagni, L.6    Galli, G.7    Francalanci, M.8    Manetti, R.9    Marra, F.10    Vanini, V.11    Maggi, E.12    Romagnani, S.13
  • 49
    • 0014030465 scopus 로고
    • Proliferation of human lympho-cytes in culture
    • Sasaki, M. S., and A. Norman. 1966. Proliferation of human lympho-cytes in culture. Nature 210:913-914.
    • (1966) Nature , vol.210 , pp. 913-914
    • Sasaki, M.S.1    Norman, A.2
  • 51
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth, G. K. 2004. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3: Article3.
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3
    • Smyth, G.K.1
  • 54
    • 61749101539 scopus 로고    scopus 로고
    • Activation of porcine natural killer cells and lysis of foot-and-mouth disease virus infected cells
    • Toka, F. N., C. K. Nfon, H. Dawson, D. M. Estes, and W. T. Golde. 2009. Activation of porcine natural killer cells and lysis of foot-and-mouth disease virus infected cells. J. Interferon Cytokine Res. 29:179-192.
    • (2009) J. Interferon Cytokine Res , vol.29 , pp. 179-192
    • Toka, F.N.1    Nfon, C.K.2    Dawson, H.3    Estes, D.M.4    Golde, W.T.5
  • 56
    • 70349580495 scopus 로고    scopus 로고
    • Increased TTS abrogates IDO-mediated CD4(+) T cells suppression in patients with graves' disease
    • Wang, S., C. Mao, Z. Zhao, Q. Gu, M. Jin, Y. Xiao, X. Jiang, Y. Zhao, Y. Zhang, and G. Ning. 2009. Increased TTS abrogates IDO-mediated CD4(+) T cells suppression in patients with graves' disease. Endocrine 36:119-125.
    • (2009) Endocrine , vol.36 , pp. 119-125
    • Wang, S.1    Mao, C.2    Zhao, Z.3    Gu, Q.4    Jin, M.5    Xiao, Y.6    Jiang, X.7    Zhao, Y.8    Zhang, Y.9    Ning, G.10
  • 57
    • 25644446917 scopus 로고    scopus 로고
    • Confirmation of QTL on porcine chromosomes 1 and 8 influencing leukocyte numbers, haematological parameters and leukocyte function
    • Wattrang, E., M. Almqvist, A. Johansson, C. Fossum, P. Wallgren, G. Pielberg, L. Andersson, and I. Edfors-Lilja. 2005. Confirmation of QTL on porcine chromosomes 1 and 8 influencing leukocyte numbers, haematological parameters and leukocyte function. Anim. Genet. 36:337-345.
    • (2005) Anim. Genet. , vol.36 , pp. 337-345
    • Wattrang, E.1    Almqvist, M.2    Johansson, A.3    Fossum, C.4    Wallgren, P.5    Pielberg, G.6    Andersson, L.7    Edfors-Lilja, I.8
  • 58
    • 77955007892 scopus 로고    scopus 로고
    • Gene expression profiling in the lungs of pigs with differ-ent susceptibilities to glasser's disease
    • Wilkinson, J. M., C. A. Sargent, L. Galina-Pantoja, and A. W. Tucker. 2010. Gene expression profiling in the lungs of pigs with differ-ent susceptibilities to glasser's disease. BMC Genomics 11:455.
    • (2010) BMC Genomics. , vol.11 , pp. 455
    • Wilkinson, J.M.1    Sargent, C.A.2    Galina-Pantoja, L.3    Tucker, A.W.4
  • 60
    • 70149095785 scopus 로고    scopus 로고
    • Critical roles of translationally controlled tumor protein in the homeostasis and TCR-mediated proliferation of peripheral T cells
    • Wu, P. S., C. Y. Yang, J. J. Yen, C. H. Chou, S. H. Chen, C. K. Wang, Y. G. Lai, N. S. Liao, and H. F Yang-Yen. 2009. Critical roles of translationally controlled tumor protein in the homeostasis and TCR-mediated proliferation of peripheral T cells. J. Immunol. 183:2373-2381.
    • (2009) J. Immunol. , vol.183 , pp. 2373-2381
    • Wu, P.S.1    Yang, C.Y.2    Yen, J.J.3    Chou, C.H.4    Chen, S.H.5    Wang, C.K.6    Lai, Y.G.7    Liao, N.S.8    Yang-Yen, H.F.9
  • 62
    • 33644694831 scopus 로고    scopus 로고
    • Human T cell cytokine responses are dependent on multidrug resistance protein-1
    • Zhang, J., M. A. Alston, H. Huang, and R. L. Rabin. 2006. Human T cell cytokine responses are dependent on multidrug resistance protein-1. Int. Immunol. 18:485-493.
    • (2006) Int. Immunol. , vol.18 , pp. 485-493
    • Zhang, J.1    Alston, M.A.2    Huang, H.3    Rabin, R.L.4


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