Intervertebral disc decompression following endplate damage: Implications for disc degeneration depend on spinal level and age

Spine

Volumn 38, Issue 17, 2013, Pages 1473-1481

  Dolan, Patricia ^a   Luo, Jin ^b   Pollintine, Phillip ^a   Landham, Priyan R ^a   Stefanakis, Manos ^c   Adams, Michael A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF ROEHAMPTON   (United Kingdom)

^c EUROPEAN UNIVERSITY CYPRUS   (Cyprus)

Author keywords

endplate fracture; intervertebral disc degeneration; intradiscal pressure; phenotype; spinal level

Indexed keywords

ADULT; AGE; AGED; ARTICLE; BONE MASS; BONE STRESS; CADAVER; FEMALE; HUMAN; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LUMBAR SPINE; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; SPINAL CORD DECOMPRESSION; SPINE; THORACIC SPINE; VERTEBRA BODY;

EID: 84882455756     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318290f3cc     Document Type: Article

References (67)

1. Cheung KM, Karppinen J, Chan D, et al. Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals. Spine 2009;34:934-40.
2. de Schepper EI, Damen J, van Meurs JB, et al. The association between lumbar disc degeneration and low back pain: the infl uence of age, gender, and individual radiographic features. Spine 2010;35:531-6.
3. Bendix T, Kjaer P, Korsholm L. Burned-out discs stop hurting: fact or fi ction Spine 2008;33:E962-7.
4. Videman T, Battie MC, Gibbons LE, et al. Associations between back pain history and lumbar MRI fi ndings. Spine 2003;28:582-8.
5. Boos N, Rieder R, Schade V, et al. 1995 Volvo Award in clinical sciences. The diagnostic accuracy of magnetic resonance imaging, work perception, and psychosocial factors in identifying symptomatic disc herniations. Spine 1995;20:2613-25.
6. Videman T, Nurminen M. The occurrence of anular tears and their relation to lifetime back pain history: a cadaveric study using barium sulfate discography. Spine 2004;29:2668-76.
7. Peng B, Hou S, Wu W, et al. The pathogenesis and clinical signifi-cance of a high-intensity zone (HIZ) of lumbar intervertebral disc on MR imaging in the patient with discogenic low back pain. Eur Spine J 2006;15:583-7.
8. Jensen MC, Brant-Zawadzki MN, Obuchowski N, et al. Magnetic resonance imaging of the lumbar spine in people without back pain. N Engl J Med 1994;331:69-73.
9. Hamanishi C, Kawabata T, Yosii T, et al. Schmorl's nodes on magnetic resonance imaging. Their incidence and clinical relevance. Spine 1994;19:450-3.
10. Freemont AJ, Peacock TE, Goupille P, et al. Nerve ingrowth into diseased intervertebral disc in chronic back pain. Lancet 1997;350:178-81.
11. Coppes MH, Marani E, Thomeer RT, et al. Innervation of "painful" lumbar discs. Spine 1997;22:2342-9;discussion 9-50.
12. Adams MA, Dolan P. Intervertebral disc degeneration: evidence for two distinct phenotypes. J Anatomy 2012;221:497-506.
13. Battie MC, Videman T, Levalahti E, et al. Genetic and environmental effects on disc degeneration by phenotype and spinal level: a multivariate twin study. Spine 2008;33:2801-8.
14. Mok FP, Samartzis D, Karppinen J, et al. ISSLS prize winner: Prevalence, determinants, and association of Schmorl nodes of the lumbar spine with disc degeneration: a population-based study of 2449 individuals. Spine (Phila Pa 1976) 2010;35:1944-52.
15. Wang Y, Videman T, Battie MC. ISSLS prize winner: lumbar vertebral endplate lesions: associations with disc degeneration and back pain history. Spine (Phila Pa 1976) 2012;37:1490-6.
16. Adams MA, Hutton WC. Prolapsed intervertebral disc. A hyperfl exion injury 1981 Volvo Award in Basic Science. Spine 1982;7:184-91.
17. Adams MA, Hutton WC. Gradual disc prolapse. Spine 1985;10:524-31.
18. Adams MA, Freeman BJ, Morrison HP, et al. Mechanical initiation of intervertebral disc degeneration. Spine 2000;25:1625-36.
19. Holm S, Holm AK, Ekstrom L, et al. Experimental disc degeneration due to endplate injury. J Spinal Disord Tech 2004;17:64-71.
20. Zhao F, Pollintine P, Hole BD, et al. Discogenic origins of spinal instability. Spine 2005;30:2621-30.
21. Pollintine P, Dolan P, Tobias JH, et al. Intervertebral disc degeneration can lead to "stress-shielding" of the anterior vertebral body: a cause of osteoporotic vertebral fracture Spine 2004;29:774-82.
22. Luo J, Skrzypiec DM, Pollintine P, et al. Mechanical effi cacy of vertebroplasty: infl uence of cement type, BMD, fracture severity, and disc degeneration. Bone 2007;40:1110-9.
23. Pollintine P, van Tunen MS, Luo J, et al. Time-dependent compressive deformation of the ageing spine: relevance to spinal stenosis. Spine (Phila Pa 1976) 2010;35:386-94.
24. McMillan DW, Garbutt G, Adams MA. Effect of sustained loading on the water content of intervertebral discs: implications for disc metabolism. Ann Rheum Dis 1996;55:880-7.
25. Adams MA, McNally DS, Dolan P. 'Stress' distributions inside intervertebral discs. The effects of age and degeneration. J Bone Joint Surg [Br] 1996;78:965-72.
26. McMillan DW, McNally DS, Garbutt G, et al. Stress distributions inside intervertebral discs: the validity of experimental "stress profi lometry.' Proc Inst Mech Eng [H] 1996;210:81-7.
27. McNally DS, Adams MA, Goodship AE. Development and validation of a new transducer for intradiscal pressure measurement. J Biomed Eng 1992;14:495-8.
28. Chu JY, Skrzypiec D, Pollintine P, et al. Can compressive stress be measured experimentally within the annulus fi brosus of degenerated intervertebral discs Proc Inst Mech Eng [H] 2008;222:161-70.
29. Pollintine P, Przybyla AS, Dolan P, et al. Neural arch load-bearing in old and degenerated spines. J Biomech 2004;37:197-204.
30. Dolan P, Earley M, Adams MA. Bending and compressive stresses acting on the lumbar spine during lifting activities. J Biomech 1994;27:1237-48.
31. Jiang G, Luo J, Pollintine P, et al. Vertebral fractures in the elderly may not always be "osteoporotic. " Bone 2010;47:111-6.
32. Green TP, Allvey JC, Adams MA. Spondylolysis. Bending of the inferior articular processes of lumbar vertebrae during simulated spinal movements. Spine 1994;19:2683-91.
33. Adams MA, Dolan P, Hutton WC. The stages of disc degeneration as revealed by discograms. J Bone Joint Surg [Br] 1986;68:36-41.
34. Zhao FD, Pollintine P, Hole BD, et al. Vertebral fractures usually affect the cranial endplate because it is thinner and supported by less-dense trabecular bone. Bone 2009;44:372-9.
35. Adams MA. Mechanical testing of the spine. An appraisal of methodology, results, and conclusions. Spine 1995;20:2151-6.
36. Nachemson AL. Disc pressure measurements. Spine 1981;6:93-7.
37. Wilke HJ, Neef P, Caimi M, et al. New in vivo measurements of pressures in the intervertebral disc in daily life. Spine 1999;24:755-62.
38. McNally DS, Shackleford IM, Goodship AE, et al. In vivo stress measurement can predict pain on discography. Spine 1996;21:2580-7.
39. Sato K, Kikuchi S, Yonezawa T. In vivo intradiscal pressure measurement in healthy individuals and in patients with ongoing back problems. Spine 1999;24:2468-74.
40. Brinckmann P, Biggemann M, Hilweg D. Prediction of the compressive strength of human lumbar vertebrae. Spine 1989;14:606-10.
41. Hansson T, Roos B. The amount of bone mineral and Schmorl's nodes in lumbar vertebrae. Spine 1983;8:266-71.
42. Rolander SD, Blair WE. Deformation and fracture of the lumbar vertebral end plate. Orthop Clin North Am 1975;6:75-81.
43. Brinckmann P, Horst M. The infl uence of vertebral body fracture, intradiscal injection, and partial discectomy on the radial bulge and height of human lumbar discs. Spine 1985;10:138-45.
44. Tzermiadianos MN, Renner SM, Phillips FM, et al. Altered disc pressure profi le after an osteoporotic vertebral fracture is a risk factor for adjacent vertebral body fracture. Eur Spine J 2008;17:1522-30.
45. Adams MA, McNally DS, Wagstaff J, et al. Abnormal stress concentrations in lumbar intervertebral discs following damage to the vertebral body: a cause of disc failure. Eur Spine J 1993;1:214-21.
46. Przybyla A, Pollintine P, Bedzinski R, et al. Outer annulus tears have less effect than endplate fracture on stress distributions inside intervertebral discs: relevance to disc degeneration. Clin Biomech 2006;21:1013-9.
47. Crock HV. Internal disc disruption. A challenge to disc prolapse fi fty years on. Spine 1986;11:650-3.
48. Gunzburg R, Parkinson R, Moore R, et al. A cadaveric study comparing discography, magnetic resonance imaging, histology, and mechanical behavior of the human lumbar disc. Spine 1992;17:417-26.
49. Ranu HS. Multipoint determination of pressure-volume curves in human intervertebral discs. Ann Rheum Dis 1993;52:142-6.
50. Niemelainen R, Battie MC, Gill K, et al. The prevalence and characteristics of thoracic magnetic resonance imaging fi ndings in men. Spine 2008;33:2552-9.
51. Koeller W, Meier W, Hartmann F. Biomechanical properties of human intervertebral discs subjected to axial dynamic compression. A comparison of lumbar and thoracic discs. Spine 1984;9:725-33.
52. Panjabi MM, Goel V, Oxland T, et al. Human lumbar vertebrae. Quantitative three-dimensional anatomy. Spine 1992;17:299-306.
53. Wagner DR, Reiser KM, Lotz JC. Glycation increases human annulus fi brosus stiffness in both experimental measurements and theoretical predictions. J Biomech 2006;39:1021-9.
54. Ishihara H, McNally DS, Urban JP, et al. Effects of hydrostatic pressure on matrix synthesis in different regions of the intervertebral disk. J Appl Physiol 1996;80:839-46.
55. Handa T, Ishihara H, Ohshima H, et al. Effects of hydrostatic pressure on matrix synthesis and matrix metalloproteinase production in the human lumbar intervertebral disc. Spine 1997;22:1085-91.
56. Walter BA, Korecki CL, Purmessur D, et al. Complex loading affects intervertebral disc mechanics and biology. Osteoarthr Cartilage 2011;19:1011-8.
57. Omlor GW, Nerlich AG, Wilke HJ, et al. A new porcine in vivo animal model of disc degeneration: response of anulus fi brosus cells, chondrocyte-like nucleus pulposus cells, and notochordal nucleus pulposus cells to partial nucleotomy. Spine 2009;34:2730-9.
58. Shirazi-Adl A. Finite-element simulation of changes in the fl uid content of human lumbar discs. Mechanical and clinical implications. Spine 1992;17:206-12.
59. Kerttula LI, Serlo WS, Tervonen OA, et al. Post-traumatic fi ndings of the spine after earlier vertebral fracture in young patients: clinical and MRI study. Spine 2000;25:1104-8.
60. Videman T, Battie MC, Gill K, et al. Magnetic resonance imaging fi ndings and their relationships in the thoracic and lumbar spine. Insights into the etiopathogenesis of spinal degeneration. Spine 1995;20:928-35.
61. Niemelainen R, Battie MC, Videman T. Risk indicators for severe upper or mid back pain in men. Spine 2011;36:E326-33.
62. Williams FM, Manek NJ, Sambrook PN, et al. Schmorl's nodes: common, highly heritable, and related to lumbar disc disease. Arthritis Rheum 2007;57:855-60.
63. Luoma K, Vehmas T, Gronblad M, et al. MRI follow-up of subchondral signal abnormalities in a selected group of chronic low back pain patients. Eur Spine J 2008;17:1300-8.
64. Kerttula L, Luoma K, Vehmas T, et al. Modic type I change may predict rapid progressive, deforming disc degeneration: a prospective 1-year follow-up study. Eur Spine J 2012;21:1135-42.
65. Kokubun S, Sakurai M, Tanaka Y. Cartilaginous endplate in cervical disc herniation. Spine 1996;21:190-5.
66. Veres SP, Robertson PA, Broom ND. The morphology of acute disc herniation: a clinically relevant model defi ning the role of fl exion. Spine 2009;34:2288-96.
67. Rajasekeran S, Bajaj N, Tubaki V, et al. An in-vivo study on 'Anatomy of failure' and proposal for a structural classifi cation of Lumbar Disc Herniation. Paper presented at: International Society for the Study of the Lumbar Spine (ISSLS); 2012; Amsterdam.