The effect of statins on risk and survival of gynecological malignancies

Gynecologic Oncology

Volumn 130, Issue 3, 2013, Pages 615-619

  Lavie, Ofer ^a   Pinchev, Mila ^a   Rennert, Hedy S ^a   Segev, Yakir ^a   Rennert, Gad ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Endometrial cancer; Ovarian cancer; Risk; Statins; Survival

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BODY MASS; BREAST FEEDING; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOMETRIUM CANCER; ETHNIC GROUP; FAMILY HISTORY; FEMALE; FRUIT; GYNECOLOGIC CANCER; HUMAN; MAJOR CLINICAL STUDY; MEDICAL RECORD; MENOPAUSE; OVARY CANCER; PREGNANCY; PRIORITY JOURNAL; RISK ASSESSMENT; SEX DIFFERENCE; SPORT; VEGETABLE;

ENDOMETRIAL CANCER; OVARIAN CANCER; RISK; STATINS; SURVIVAL;

AGED; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; ISRAEL; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; ODDS RATIO; OVARIAN NEOPLASMS; PROPORTIONAL HAZARDS MODELS; SURVIVAL RATE;

EID: 84882453287     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2013.05.025     Document Type: Article

References (25)

1. M. Schachter Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update Fundam Clin Pharmacol 19 2005 117 125
2. J. Rutishauser Statins in clinical medicine Swiss Med Wkly 141 2011 w13310
3. E.J. Mills, B. Rachlis, and P. Wu Primary prevention of cardiovascular mortality and events with statin treatments. A network meta-analysis involving more than 65,000 patients J Am Coll Cardiol 25 2008 1769 1781
4. J.N. Poynter, S.B. Gruber, and P.D.R. Higgins Statins and the risk of colorectal cancer N Engl J Med 352 2005 2184 2192
5. V. Khurana, H.R. Bejjanki, and G. Caldito Statins reduce the risk of lung cancer in humans: a large case-control study of US veterans Chest 131 2007 1282 1288
6. H.F. Chiu, S.C. Ho, and C.C. Chen Statin use and the risk of liver cancer: a population-based case-control study Am J Gastroenterol 106 2011 894 898
7. M.L. Taylor, B.J. Wells, and M.J. Smolak Statins and cancer: a meta-analysis of case-control studies Eur J Cancer Prev 17 2008 259 268
8. E.J. Jacobs, C.C. Newton, and M.J. Thun Long-term use of cholesterol-lowering drugs and cancer incidence in a large United States cohort Breast Cancer Res Treat 109 2008 573 579 2008
9. P. Gazzerro, M.C. Proto, and G. Gangemi Pharmacological actions of statins: a critical appraisal in the management of cancer Pharmacol Rev 64 2012 102 146
10. D. Yizhaki, H.S. Rennert, and G. Rosen Validity and reproducibility of a semi-quantitative food frequency questionnaire adapted to an Israeli population Open Nutr J 2 2008 9 14
11. D. Boudreau, O. Yu, and D. Buist Statin use and prostate cancer risk in a large population based setting Cancer Causes Control 19 2008 767 774
12. O. Yu, D.M. Boudreau, and D.S. Buist Statin use and female reproductive organ cancer risk in a large population-based setting Cancer Causes Control 20 2009 609 616
13. G.D. Friedman, E.D. Flick, and N. Udaltsova Screening statins for possible carcinogenic risk: up to 9 years of follow-up of 361,859 recipients Pharmacoepidemiol Drug Saf 17 2008 27 36
14. S. Friis, A.H. Poulsen, and S.P. Johnsen Cancer risk among statin users: a population-based cohort study Int J Cancer 114 2005 643 647
15. P.F. Coogan, L. Rosenberg, and B.L. Strom Statin use and the risk of 10 cancers Epidemiology 18 2007 213 219
16. J.A. Kaye, and H. Jick Statin use and cancer risk in the General Practice Research Database Br J Cancer 90 2004 635 637
17. L. Blais, A. Desgagne, and J. LeLorier 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: a nested case-control study Arch Intern Med 160 2000 2363 2368
18. E.J. Jacobs, C.C. Newton, and M.J. Thun Long-term use of cholesterol-lowering drugs and cancer incidence in a large United States cohort Cancer Res 71 2011 1763 1771
19. S.M. Lipkin, L. Chao, and V. Moreno Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer Cancer Prev. Res. 3 2010 597 603 (Phila Pa)
20. M.L. Kwan, L.A. Habel, and E.D. Flick Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors Cancer Res 71 2011 1763 1771
21. T.P. Ahern, L. Pedersen, and M. Tarp Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study J Natl Cancer Inst 103 2011 1461 1468
22. R.G. Elmore, Y. Ioffe, and D.R. Scoles Impact of statin therapy on survival in epithelial ovarian cancer Gynecol Oncol 111 2008 102 105
23. D.J. Brennan, H. Laursen, and D.P. O'Connor Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen Breast Cancer Res 13 2011 R12
24. A. Martirosyan, J.W. Clendening, and C.A. Goard Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance BMC Cancer 10 2010 103
25. A. Horiuchi, N. Kikuchi, and R. Osada Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer Cancer Sci 99 2008 2532 2539