Quantification of pentane in exhaled breath, a potential biomarker of bowel disease, using selected ion flow tube mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 27, Issue 17, 2013, Pages 1983-1992

  Dryahina, Kseniya ^a   Španěl, Patrik ^a   Pospíšilová, Veronika ^a,b   Sovová, Kristýna ^a,b   Hrdlička, Luděk ^b,c   MacHková, Naděžda ^b,c   Lukáš, Milan ^b,c   Smith, David ^d  

^a J HEYROVSKÝ INSTITUTE OF PHYSICAL CHEMISTRY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c ISCARE as   (Czech Republic)

^d KEELE UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; DIGITAL STORAGE; DISEASES; GAS CHROMATOGRAPHY; IONS; NONINVASIVE MEDICAL PROCEDURES; PARAFFINS; PHASE INTERFACES; REACTION KINETICS; URANIUM COMPOUNDS;

CROHN DISEASE; CURRENT DIAGNOSTICS; DIAGNOSTIC METHODS; EXHALED BREATHS; HUMAN BREATH; INFLAMMATORY BOWEL DISEASE; LIMITED SENSITIVITY; PRODUCT IONS; SELECTED ION FLOW TUBES; ULCERATIVE COLITIS;

MASS SPECTROMETRY;

EID: 84882428422     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.6660     Document Type: Article

References (58)

1. A. Amann, D. Smith,. Breath Analysis for Clinical Diagnosis and Therapeutic Monitoring. World Scientific, Singapore, 2005.
2. A. Amann, D. Smith,. Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine. Elsevier, 2013.
3. T. H. Risby, S. F. Solga,. Current status of clinical breath analysis. Appl. Phys. B -Lasers and Optics 2006, 85, 421.
4. P. Španěl, D. Smith,. Progress in SIFT-MS; breath analysis and other applications. Mass Spectrom. Rev. 2011, 30, 236.
5. D. Smith, P. Španěl,. Selected ion flow tube mass spectrometry (SIFT-MS) for on-line trace gas analysis. Mass Spectrom. Rev. 2005, 24, 661.
6. K. Schwarz, W. Filipiak, A. Amann,. Determining concentration patterns of volatile compounds in exhaled breath by PTR-MS. J. Breath Res. 2009, 3, 027002.
7. J. King, P. Mochalski, A. Kupferthaler, K. Unterkofler, H. Koc, W. Filipiak, S. Teschl, H. Hinterhuber, A. Amann,. Dynamic profiles of volatile organic compounds in exhaled breath as determined by a coupled PTR-MS/GC-MS study. Physiological Measurement 2010, 31, 1169.
8. D. Smith, P. Španěl,. Direct, rapid quantitative analyses of BVOCs using SIFT-MS and PTR-MS obviating sample collection. TRAC-Trends Anal. Chem. 2011, 30, 945.
9. P. Španěl, D. Smith,. Volatile compounds in health and disease. Curr. Opin. Clin. Nutr. Metab. Care 2011, 14, 455.
10. D. Smith, C. Turner, P. Španěl,. Volatile metabolites in the exhaled breath of healthy volunteers: their levels and distributions. J. Breath Res. 2007, 1, 014004.
11. C. Turner, P. Španěl, D. Smith,. A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS. Physiological Measurement 2006, 27, 321.
12. C. Turner, P. Španěl, D. Smith,. A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS). Physiological Measurement 2006, 27, 13.
13. C. Turner, P. Španěl, D. Smith,. A longitudinal study of ethanol and acetaldehyde in the exhaled breath of healthy volunteers using selected-ion flow-tube mass spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 61.
14. C. Turner, P. Španěl, D. Smith,. A longitudinal study of methanol in the exhaled breath of 30 healthy volunteers using selected ion flow tube mass spectrometry, SIFT-MS. Physiological Measurement 2006, 27, 637.
15. I. Horvath, Z. Lazar, N. Gyulai, M. Kollai, G. Losonczy,. Exhaled biomarkers in lung cancer. Eur. Respir. J. 2009, 34, 261.
16. W. Filipiak, V. Ruzsanyi, P. Mochalski, A. Filipiak, A. Bajtarevic, C. Ager, H. Denz, W. Hilbe, H. Jamnig, M. Hackl, A. Dzien, A. Amann,. Dependence of exhaled breath composition on exogenous factors, smoking habits and exposure to air pollutants. J. Breath Res. 2012, 6, 036008.
17. B. Wzorek, P. Mochalski, I. Sliwka, A. Amann,. Application of GC-MS with a SPME and thermal desorption technique for determination of dimethylamine and trimethylamine in gaseous samples for medical diagnostic purposes. J. Breath Res. 2010, 4, 026002.
18. P. Spanel, D. Smith,. Progress in SIFT-MS: breath analysis and other applications. Mass Spectrom. Rev. 2011, 30, 236.
19. D. Smith, P. Španěl,. Ambient analysis of trace compounds in gaseous media by SIFT-MS. Analyst 2011, 136, 2009.
20. P. Španěl, K. Dryahina, D. Smith,. A general method for the calculation of absolute trace gas concentrations in air and breath from selected ion flow tube mass spectrometry data. Int. J. Mass Spectrom. 2006, 249, 230.
21. P. Španěl, T. S. Wang, D. Smith,. Quantification of hydrogen cyanide in humid air by selected ion flow tube mass spectrometry. Rapid Commun. Mass Spectrom. 2004, 18, 1869.
22. P. Španěl, D. Smith,. Quantification of hydrogen sulphide in humid air by selected ion flow tube mass spectrometry. Rapid Commun. Mass Spectrom. 2000, 14, 1136.
23. P. Španěl, D. Smith, T. A. Holland, W. Al Singary, J. B. Elder,. Analysis of formaldehyde in the headspace of urine from bladder and prostate cancer patients using selected ion flow tube mass spectrometry. Rapid Commun. Mass Spectrom. 1999, 13, 1354.
24. K. Dryahina, D. Smith, P. Španěl,. Quantification of methane in humid air and exhaled breath using selected ion flow tube mass spectrometry. Rapid Commun. Mass Spectrom. 2010, 24, 1296.
25. B. Ross, S. Shah, M. Peet,. Increased breath ethane and pentane concentrations in currently unmedicated patients with schizophrenia. Open J. Psychiatry 2011, 1, 1.
26. S. Mendis, P. A. Sobotka, D. E. Euler,. Pentane and isoprene in expired air from humans-gas-chromatographic analysis of single-breath. Clin. Chem. 1994, 40, 1485.
27. C. O. Olopade, J. A. Christon, M. Zakkar, C. W. Hua, W. I. Swedler, P. A. Scheff, I. Rubinstein,. Exhaled pentane and nitric oxide levels in patients with obstructive sleep apnea. Chest 1997, 111, 1500.
28. C. O. Olopade, M. Zakkar, W. I. Swedler, I. Rubinstein,. Exhaled pentane levels in acute asthma. Chest 1997, 111, 862.
29. D. Poli, P. Carbognani, M. Corradi, M. Goldoni, O. Acampa, B. Balbi, L. Bianchi, M. Rusca, A. Mutti,. Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study. Respir. Res. 2005, 6, 71.
30. M. Phillips, M. Sabas, J. Greenberg,. Increased pentane and carbon-disulfide in the breath of patients with schizophrenia. J. Clin. Pathol. 1993, 46, 861.
31. A. Vangossum, J. Decuyper,. Breath alkanes as an index of lipid-peroxidation. Eur. Respir. J. 1989, 2, 787.
32. G. Spiteller,. Peroxidation of linoleic acid and its relation to aging and age dependent diseases. Mechanisms Ageing Develop. 2001, 122, 617.
33. A. Rosa, G. Appendino, M. P. Melis, M. Deiana, A. Atzeri, I. Alessandra, A. Minassi, M. A. Dessi,. Protective effect and relation structure-Activity of nonivamide and iododerivatives in several models of lipid oxidation. Chemico-Biological Interactions 2009, 180, 183.
34. J.-K. Kim, H.-W. Cho, J.-H. Han, S.-B. Lee, Y.-H. Chung, K.-T. Rim, J.-S. Yang,. Subchronic Inhalation Toxicity Study of n-pentane in Rats. Saf. Health Work 2012, 3, 224.
35. U. Frommer, V. Ullrich, H. Stauding,. Hydroxylation of aliphatic compounds by liver microsomes. 1. Distribution pattern of isomeric alcohols. Hoppe-Seylers Zeitschrift fur Physiologische Chemie 1970, 351, 903.
36. S. R. B. Allerheiligen, T. M. Ludden, R. F. Burk,. The pharmacokinetics of pentane, a by-product of lipid-peroxidation. Drug Metabo. Dispos. 1987, 15, 794.
37. J. Kokoszka, R. L. Nelson, W. I. Swedler, J. Skosey, H. Abcarian,. Determination of inflammatory bowel-disease activity by breath pentane analysis. Diseases of the Colon & Rectum 1993, 36, 597.
38. S. Sedghi, A. Keshavarzian, M. Klamut, D. Eiznhamer, E. J. Zarling,. Elevated breath ethane levels in active ulcerative-colitis-evidence fir excessive lipid-peroxidation. Am. J. Gastroenterol. 1994, 89, 2217.
39. G. Van Assche, A. Dignass, J. Panes, L. Beaugerie, J. Karagiannis, M. Allez, T. Ochsenkuhn, T. Orchard, G. Rogler, E. Louis, L. Kupcinskas, G. Mantzaris, S. Travis, E. Stange, Ecco. The second European evidence-based consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis. J. Crohns & Colitis 2010, 4, 7.
40. M. Lukas, M. Bortlik, Z. Maratka,. What is the origin of ulcerative colitis? Still more questions than answers. Postgrad. Med. J. 2006, 82, 620.
41. I. Ahmed, R. Greenwood, B. D. Costello, N. M. Ratcliffe, C. S. Probert,. An investigation of fecal volatile organic metabolites in irritable bowel syndrome. Plos One 2013, 8, 13.
42. G. D'Haens, W. J. Sandborn, B. G. Feagan, K. Geboes, S. B. Hanauer, E. J. Irvine, M. Lemann, P. Marteau, P. Rutgeerts, J. Scholmerich, L. R. Sutherland,. A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology 2007, 132, 763.
43. B. E. Wendland, E. Aghdassi, C. Tam, J. Carrrier, A. H. Steinhart, S. L. Wolman, D. Baron, J. P. Allard,. Lipid peroxidation and plasma antioxidant micronutrients in Crohn disease. Am. J. Clin. Nutr. 2001, 74, 259.
44. + with several aromatic and aliphatic hydrocarbons. Int. J. Mass Spectrom. 1998, 181, 1.
45. G. J. Francis, P. F. Wilson, D. B. Milligan, V. S. Langford, M. T. McEwan,. GeoVOC: A SIFT-MS method for the analysis of small linear hydrocarbons of relevance to oil exploration. Int. J. Mass Spectrom. 2007, 268, 38.
46. + ions with some organic molecules: The potential for trace gas analysis of air. J. Chem. Phys. 1996, 104, 1893.
47. P. Španěl, D. Smith,. Influence of weakly bound adduct ions on breath trace gas analysis by selected ion flow tube mass spectrometry (SIFT-MS). Int. J. Mass Spectrom. 2009, 280, 128.
48. N. G. Adams, D. Smith,. Selected ion flow tube (SIFT)-technique for studying ion-neutral reactions. Int. J. Mass Spectrom. Ion Processes 1976, 21, 349.
49. + ions with some organic molecules: The potential for trace gas analysis of air. J. Chem. Phys. 1996, 104, 1893.
50. D. Smith, P. Španěl, J. M. Thompson, B. Rajan, J. Cocker, P. Rolfe,. The selected ion flow tube method for workplace analyses of trace gases in air and breath: Its scope, validation, and applications. Appl. Occupational Environ. Hyg. 1998, 13, 817.
51. + with C-3 hydrocarbons propane, propene, and propyne. J. Phys. Chem. A 2011, 115, 7310.
52. + with six volatile phytogenic esters. Int. J. Mass Spectrom. 2011, 300, 31.
53. + with seven isomers of hexanol in support of SIFT-MS. Int. J. Mass Spectrom. 2012, 319, 25.
54. T. Wang, A. Pysanenko, K. Dryahina, P. Španěl, D. Smith,. Analysis of breath, exhaled via the mouth and nose, and the air in the oral cavity. J. Breath Res. 2008, 2, 037013.
55. K. Dryahina, D. Smith, P. Spanel,. Quantification of methane in humid air and exhaled breath using selected ion flow tube mass spectrometry. Rapid Commun. Mass Spectrom. 2010, 24, 1296.
56. P. Španěl, D. Smith,. On-line measurement of the absolute humidity of air, breath and liquid headspace samples by selected ion flow tube mass spectrometry. Rapid Commun. Mass Spectrom. 2001, 15, 563.
57. P. Španěl, D. Smith,. Advances in on-line absolute trace gas analysis by SIFT-MS. Curr. Anal. Chem. 2013, 9, 525.
58. M. Corradi, P. Pignatti, P. Manini, R. Andreoli, M. Goldoni, M. Poppa, G. Moscato, B. Balbi, A. Mutti,. Comparison between exhaled and sputum oxidative stress biomarkers in chronic airway inflammation. Eur. Respir. J. 2004, 24, 1011.