Controlled release of rat adipose-derived stem cells from alginate microbeads

Biomaterials

Volumn 34, Issue 33, 2013, Pages 8172-8184

  Leslie, Shirae K ^a,b   Cohen, David J ^a,b   Sedlaczek, Janina ^a,c   Pinsker, Eric J ^a   Boyan, Barbara D ^a,b   Schwartz, Zvi ^a,b  

^a Emory University   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Alginate degradation; Cell encapsulation; Hydrogel; Stem cells

Indexed keywords

ADIPOSE DERIVED STEM CELLS; CELL ENCAPSULATIONS; CELL-BASED THERAPY; CONTROLLED DEGRADATION; CONTROLLED RELEASE; ELECTROSTATIC POTENTIALS; IMPLANTATION SITES; INJECTABLE HYDROGELS;

CYTOLOGY; HYDROGELS; RATS; STEM CELLS;

ALGINATE;

ALGINIC ACID; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; NOGGIN; OSTEOCALCIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN A;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ARTICLE; BONE REGENERATION; CELL COUNT; CELL VIABILITY; DEGRADATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYDROGEL; IMMUNE RESPONSE; MALE; MESENCHYMAL STEM CELL; MICROENCAPSULATION; MONOLAYER CULTURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; VISCOSITY;

RATTUS;

ALGINATE DEGRADATION; CELL ENCAPSULATION; HYDROGEL; STEM CELLS;

ADIPOSE TISSUE; ALGINATES; ANIMALS; CELL SURVIVAL; GLUCURONIC ACID; HEXURONIC ACIDS; IN SITU NICK-END LABELING; MICROSPHERES; RATS; REAL-TIME POLYMERASE CHAIN REACTION; STEM CELLS; TISSUE ENGINEERING;

EID: 84881666597     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.07.017     Document Type: Article

References (32)

1. Khosla S., Westendorf J.J., Modder U.I. Concise review: insights from normal bone remodeling and stem cell-based therapies for bone repair. Stem Cells 2010, 28:2124-2128.
2. Boyan B.D., Caplan A.I., Heckman J.D., Lennon D.P., Ehler W., Schwartz Z. Osteochondral progenitor cells in acute and chronic canine nonunions. JOrthop Res 1999, 17:246-255.
3. Zuk P.A., Zhu M., Ashjian P., De Ugarte D.A., Huang J.I., Mizuno H., et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002, 13:4279-4295.
4. Dosier C.R., Erdman C.P., Park J.H., Schwartz Z., Boyan B.D., Guldberg R.E. Resveratrol effect on osteogenic differentiation of rat and human adipose derived stem cells in a 3-D culture environment. JMech Behav Biomed Mater 2011, 11:112-122.
5. Niemeyer P., Fechner K., Milz S., Richter W., Suedkamp N.P., Mehlhorn A.T., et al. Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma. Biomaterials 2010, 31:3572-3579.
6. Li F., Wang X., Niyibizi C. Distribution of single-cell expanded marrow derived progenitors in a developing mouse model of osteogenesis imperfecta following systemic transplantation. Stem Cells 2007, 25:3183-3193.
7. Alsberg E., Anderson K.W., Albeiruti A., Franceschi R.T., Mooney D.J. Cell-interactive alginate hydrogels for bone tissue engineering. JDent Res 2001, 80:2025-2029.
8. Lim F., Sun A.M. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980, 210:908-910.
9. Hauselmann H.J., Fernandes R.J., Mok S.S., Schmid T.M., Block J.A., Aydelotte M.B., et al. Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads. JCell Sci 1994, 107(Pt 1):17-27.
10. Leddy H.A., Awad H.A., Guilak F. Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. JBiomed Mater Res B 2004, 70:397-406.
11. Chicheportiche D., Reach G. Invitro kinetics of insulin release by microencapsulated rat islets: effect of the size of the microcapsules. Diabetologia 1988, 31:54-57.
12. Hasse C., Bohrer T., Barth P., Stinner B., Cohen R., Cramer H., et al. Parathyroid xenotransplantation without immunosuppression in experimental hypoparathyroidism: long-term invivo function following microencapsulation with a clinically suitable alginate. World J Surg 2000, 24:1361-1366.
13. Trouche E., Girod Fullana S., Mias C., Ceccaldi C., Tortosa F., Seguelas M.H., et al. Evaluation of alginate microspheres for mesenchymal stem cell engraftment on solid organ. Cell Transplant 2010, 19:1623-1633.
14. Rowley J.A., Madlambayan G., Mooney D.J. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 1999, 20:45-53.
15. Genes N.G., Rowley J.A., Mooney D.J., Bonassar L.J. Effect of substrate mechanics on chondrocyte adhesion to modified alginate surfaces. Arch Biochem Biophys 2004, 422:161-167.
16. Proulx M.K., Carey S.P., DiTroia L.M., Jones C.M., Fakharzadeh M., Guyette J.P., et al. Fibrin microthreads support mesenchymal stem cell growth while maintaining differentiation potential. JBiomed Mater Res A 2011, 96A:301-312.
17. Boyan BD, Kinney RC, Schwartz Z. Microencapsulation of cells in hydrogels using electrostatic potentials. US Patent No. 8202701 B2; 2012.
18. Moyer H.R., Kinney R.C., Singh K.A., Williams J.K., Schwartz Z., Boyan B.D. Alginate microencapsulation technology for the percutaneous delivery of adipose-derived stem cells. Ann Plast Surg 2010, 65:497-503.
19. Lee C.S., Moyer H.R., Gittens R.A., Williams J.K., Boskey A.L., Boyan B.D., et al. Regulating invivo calcification of alginate microbeads. Biomaterials 2010, 31:4926-4934.
20. Lee C.S., Watkins E.A., Burnsed O.A., Schwartz Z., Boyan B. Tailoring adipose stem cell trophic factor production with differentiation medium components to regenerate chondral defects. Tissue Eng A 2013, 19:1451-1464.
21. Lee C.S., Burnsed O.A., Raghuram V., Kalisvaart J., Boyan B.D., Schwartz Z. Adipose stem cells can secrete angiogenic factors that inhibit hyaline cartilage regeneration. Stem Cell Res Ther 2012, 3:35.
22. Kong H.J., Kaigler D., Kim K., Mooney D.J. Controlling rigidity and degradation of alginate hydrogels via molecular weight distribution. Biomacromolecules 2004, 5:1720-1727.
23. Ashton R.S., Banerjee A., Punyani S., Schaffer D.V., Kane R.S. Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture. Biomaterials 2007, 28:5518-5525.
24. Yamasaki M., Moriwaki S., Miyake O., Hashimoto W., Murata K., Mikami B. Structure and function of a hypothetical Pseudomonas aeruginosa protein PA1167 classified into family PL-7: a novel alginate lyase with a beta-sandwich fold. JBiol Chem 2004, 279:31863-31872.
25. Lee K.Y., Bouhadir K.H., Mooney D.J. Controlled degradation of hydrogels using multi-functional cross-linking molecules. Biomaterials 2004, 25:2461-2466.
26. Preiss J., Ashwell G. Alginic acid metabolism in bacteria. I. Enzymatic formation of unsaturated oligosaccharides and 4-deoxy-l-erythro-5-hexoseulose uronic acid. JBiol Chem 1962, 237:309-316.
27. Moen E., Horn S., Østgaard K. Alginate degradation during anaerobic digestion of Laminaria hyperborea stipes. JAppl Phycol 1997, 9:157-166.
28. Moen E., Larsen B., Østgaard K. Aerobic microbial degradation of alginate in Laminaria hyperborea stipes containing different levels of polyphenols. JAppl Phycol 1997, 9:45-54.
29. Shoichet M.S., Li R.H., White M.L., Winn S.R. Stability of hydrogels used in cell encapsulation: an invitro comparison of alginate and agarose. Biotechnol Bioeng 1996, 50:374-381.
30. Aguado B.A., Mulyasasmita W., Su J., Lampe K.J., Heilshorn S.C. Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers. Tissue Eng A 2012, 18:806-815.
31. Hermann C., Richards M.A., Williams J.K., Guldberg R.E., Vidakovic B., Boyan B.D., et al. Biphasic fusion of the murine posterior frontal suture. Plast Reconstr Surg 2013, 131:727-740.
32. Hori Y., Hu D.E., Yasui K., Smither R.L., Gresham G.A., Fan T.P. Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants. Br J Pharmacol 1996, 118:1584-1591.