Fibrin microthreads support mesenchymal stem cell growth while maintaining differentiation potential

Journal of Biomedical Materials Research - Part A

Volumn 96 A, Issue 2, 2011, Pages 301-312

  Proulx, Megan K ^a   Carey, Shawn P ^a   Ditroia, Lisa M ^a   Jones, Craig M ^a   Fakharzadeh, Michael ^a   Guyette, Jacques P ^a   Clement, Amanda L ^a   Orr, Robert G ^a   Rolle, Marsha W ^a   Pins, George D ^a   Gaudette, Glenn R ^a  

^a Worcester Polytechnic Institute   (United States)

Author keywords

fibrin; heart; mesenchymal stem cells; microthreads; myocardium

Indexed keywords

ADIPOCYTES; CELL DELIVERY; CELL DENSITY; ENGRAFTMENT; FIBRIN; HUMAN MESENCHYMAL STEM CELLS (HMSCS); LOCALIZED DELIVERY; MESENCHYMAL STEM CELL; MICROTHREADS; MYOCARDIUM; OSTEOCYTES; PLATFORM TECHNOLOGY; VIABLE CELLS;

ASSAYS; GROWTH KINETICS; STEM CELLS;

CELL CULTURE;

FIBRIN;

ADIPOCYTE; ARTICLE; CELL ADHESION; CELL DENSITY; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; OSTEOCYTE;

ADIPOCYTES; ANIMALS; BIOLOGICAL MARKERS; CATTLE; CELL ADHESION; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN; FIBRIN; GELS; HUMANS; KI-67 ANTIGEN; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; MULTIPOTENT STEM CELLS; OSTEOGENESIS; RATS; SUS SCROFA; TIME FACTORS;

EID: 78650491628     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32978     Document Type: Article

References (24)

1. Kraitchman DL, Tatsumi M, Gilson WD, Ishimori T, Kedziorek D, Walczak P, Segars WP, Chen HH, Fritzges D, Izbudak I, Young RG, Marcelino M, Pittenger MF, Solaiyappan M, Boston RC, Tsui BM, Wahl RL, Bulte JW,. Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation 2005; 112: 1451-1461. (Pubitemid 41291771)
2. Barbash IM, Chouraqui P, Baron J, Feinberg MS, Etzion S, Tessone A, Miller L, Guetta E, Zipori D, Kedes LH, Kloner RA, Leor J,. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: Feasibility, cell migration, and body distribution. Circulation 2003; 108: 863-868. (Pubitemid 37022130)
3. Hou D, Youssef EA, Brinton TJ, Zhang P, Rogers P, Price ET, Yeung AC, Johnstone BH, Yock PG, March KL,. Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: Implications for current clinical trials. Circulation 2005; 112 (9 Suppl): I150-I156. (Pubitemid 41266667)
4. Thompson CA, Nasseri BA, Makower J, Houser S, McGarry M, Lamson T, Pomerantseva I, Chang JY, Gold HK, Vacanti JP, Oesterle SN,. Percutaneous transvenous cellular cardiomyoplasty. A novel nonsurgical approach for myocardial cell transplantation. J Am Coll Cardiol 2003; 41: 1964-1971. (Pubitemid 36677117)
5. Christman KL, Vardanian AJ, Fang Q, Sievers RE, Fok HH, Lee RJ,. Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J Am Coll Cardiol 2004; 44: 654-660. (Pubitemid 39089073)
6. Ozawa T, Mickle DA, Weisel RD, Koyama N, Ozawa S, Li RK,. Optimal biomaterial for creation of autologous cardiac grafts. Circulation 2002; 106 (12 Suppl 1): I176-I182.
7. Leor J, Aboulafia-Etzion S, Dar A, Shapiro L, Barbash IM, Battler A, Granot Y, Cohen S,. Bioengineered cardiac grafts: A new approach to repair the infarcted myocardium? Circulation 2000; 102 (19 Suppl 3): III56-III61.
8. Zhang P, Zhang H, Wang H, Wei Y, Hu S,. Artificial matrix helps neonatal cardiomyocytes restore injured myocardium in rats. Artif Organs 2006; 30: 86-93.
9. Simpson D, Liu H, Fan TH, Nerem R, Dudley SC Jr,. A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myocardial remodeling. Stem Cells 2007; 25: 2350-2357. (Pubitemid 47480494)
10. Davis ME, Hsieh PC, Grodzinsky AJ, Lee RT,. Custom design of the cardiac microenvironment with biomaterials. Circ Res 2005; 97: 8-15.
11. Christman KL, Fok HH, Sievers RE, Fang Q, Lee RJ,. Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction. Tissue Eng 2004; 10: 403-409. (Pubitemid 38580261)
12. Ho W, Tawil B, Dunn JC, Wu BM,. The behavior of human mesenchymal stem cells in 3D fibrin clots: Dependence on fibrinogen concentration and clot structure. Tissue Eng 2006; 12: 1587-1595. (Pubitemid 44174792)
13. Cornwell KG, Pins GD,. Discrete crosslinked fibrin microthread scaffolds for tissue regeneration. J Biomed Mater Res A 2007; 82: 104-112.
14. Ryu JH, Kim IK, Cho SW, Cho MC, Hwang KK, Piao H, Piao S, Lim SH, Hong YS, Choi CY, Yoo KJ, Kim BS,. Implantation of bone marrow mononuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium. Biomaterials 2005; 26: 319-326. (Pubitemid 38950716)
15. Mol A, van Lieshout MI, Dam-de Veen CG, Neuenschwander S, Hoerstrup SP, Baaijens FP, Bouten CV,. Fibrin as a cell carrier in cardiovascular tissue engineering applications. Biomaterials 2005; 26: 3113-3121. (Pubitemid 39647246)
16. Rosen AB, Kelly DJ, Schuldt AJ, Lu J, Potapova IA, Doronin SV, Robichaud KJ, Robinson RB, Rosen MR, Brink PR, Gaudette GR, Cohen IS,. Finding fluorescent needles in the cardiac haystack: Tracking human mesenchymal stem cells labeled with quantum dots for quantitative in vivo three-dimensional fluorescence analysis. Stem Cells 2007; 25: 2128-2138. (Pubitemid 47258192)
17. Scholzen T, Gerdes J,. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000; 182: 311-322. (Pubitemid 30054364)
18. Catelas I, Sese N, Wu BM, Dunn JC, Helgerson S, Tawil B,. Human mesenchymal stem cell proliferation and osteogenic differentiation in fibrin gels in vitro. Tissue Eng 2006; 12: 2385-2396. (Pubitemid 44734995)
19. Gerard C, Blouin K, Tchernof A, Doillon CJ,. Adipogenesis in nonadherent and adherent bone marrow stem cells grown in fibrin gel and in the presence of adult plasma. Cells Tissues Organs 2008; 187: 186-198. (Pubitemid 351398232)
20. Barry FP, Murphy JM,. Mesenchymal stem cells: Clinical applications and biological characterization. Int J Biochem Cell Biol 2004; 36: 568-584. (Pubitemid 38324589)
21. Gaudette GR, Cohen IS,. Cardiac regeneration: Materials can improve the passive properties of myocardium, but cell therapy must do more. Circulation 2006; 114: 2575-2577.
22. Rovensky Y, Samoilov VI,. Morphogenetic response of cultured normal and transformed fibroblasts, and epitheliocytes, to a cylindrical substratum surface. Possible role for the actin filament bundle pattern. J Cell Sci 1994; 107: 1255-1263. (Pubitemid 24177326)
23. Schuldt AJ, Rosen MR, Gaudette GR, Cohen IS,. Repairing damaged myocardium: Evaluating cells used for cardiac regeneration. Curr Treat Options Cardiovasc Med 2008; 10: 59-72.
24. Laflamme MA, Murry CE,. Regenerating the heart. Nat Biotechnol 2005; 23: 845-856.