Cerebrospinal fluid tau protein as a biomarker for severity of spinal cord injury in dogs with intervertebral disc herniation

Veterinary Journal

Volumn 197, Issue 2, 2013, Pages 253-258

  Roerig, A ^a   Carlson, R ^a   Tipold, A ^a   Stein, V M ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Cerebrospinal fluid (CSF); Dog; Intervertebral disc herniation; Spinal cord injury; Tau protein

Indexed keywords

BIOLOGICAL MARKER; TAU PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CERVICAL SPINE; CONTROLLED STUDY; CONVALESCENCE; DISEASE MARKER; DISEASE SEVERITY; DOG; ENZYME LINKED IMMUNOSORBENT ASSAY; INTERVERTEBRAL DISK HERNIA; MOTOR PERFORMANCE; NONHUMAN; PARESIS; PROGNOSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SPINAL CORD INJURY; THORACOLUMBAR SPINE;

CEREBROSPINAL FLUID (CSF); DOG; INTERVERTEBRAL DISC HERNIATION; SPINAL CORD INJURY; TAU PROTEIN;

ANIMALS; BIOLOGICAL MARKERS; DOG DISEASES; DOGS; FEMALE; INTERVERTEBRAL DISC DISPLACEMENT; MALE; SPINAL CORD INJURIES; TAU PROTEINS;

CANIS FAMILIARIS;

EID: 84881661348     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2013.02.005     Document Type: Article

References (54)

1. Anderson D., Hall E. Pathophysiology of spinal cord trauma. Annals of Emergency Medicine 1993, 22:987-992.
2. Andreasen N., Vanmechelen E., Van de Voorde A., Davidsson P., Hesse C., Tarvonen S., Räihä I., Sourander L., Winblad B., Blennow K. Cerebrospinal fluid tau protein as a biochemical marker for Alzheimer's disease: A community based follow up study. Journal of Neurology, Neurosurgery and Psychiatry 1998, 64:298-305.
3. Binder L.I., Frankfurter A., Rebhun L.I. The distribution of tau in the mammalian central nervous system. Journal of Cell Biology 1985, 101:1371-1378.
4. Blennow K., Fredman P., Wallin A., Gottfries C., Langström G., Svennerholm L. Protein analyses in cerebrospinal fluid. I. Influence of concentration gradients for proteins on cerebrospinal fluid/serum albumin ratio. European Neurology 1993, 33:126-128.
5. Blennow K., Wallin A., Agren H., Spenger C., Siegfried J., Vanmechelen E. Tau protein in cerebrospinal fluid. Molecular and Chemical Neuropathology 1995, 26:231-245.
6. Blomberg M., Jensen M., Bsun H., Lannfelt L., Wahlund L. CSF tau levels increase with age in healthy individuals. Dementia and Geriatric Cognitive Disorders 2001, 12:127-132.
7. Boekhoff T., Flieshardt C., Ensinger E., Fork M., Kramer S., Tipold A. Quantitative magnetic resonance imaging characteristics: Evaluation of prognostic value in the dog as a translational model for spinal cord injury. Journal of Spinal Disorders and Techniques 2012, 25:E81-E87.
8. Brandt R., Lee G. Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro. Journal of Biological Chemistry 1993, 268:3414-3419.
9. Brisby H., Olmarker K., Rosengren L., Cederlund C., Rydevik B. Markers of nerve tissue injury in the cerebrospinal fluid in patients with lumbar herniation and sciatica. Spine 1999, 24:742-746.
10. Brisson B.A. Intervertebral disease in dogs. The Veterinary Clinics of North America: Small Animal Practice 2010, 40:829-858.
11. Buee L., Bussiere T., Buee-Scherrer V., Delacourte A., Hof P.R. Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Research Reviews 2000, 33:95-130.
12. Carlson G., Gorden C., Oliff H., Pillai J., LaManna J. Sustained spinal cord compression: Part I: Time-dependent effect on long-term pathophysiology. Journal of Bone and Joint Surgery 2003, 85:86-94.
13. Crowe M., Bresnahan J., Shuman S., Masters J., Beattie M. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nature Medicine 1997, 3:73-76.
14. Davis G.J., Brown D.C. Prognostic indicators for time to ambulation after surgical decompression in nonambulatory dogs with acute thoracolumbar disk extrusions: 112 cases. Veterinary Surgery 2002, 31:513-518.
15. Drubin D.G. Tau protein function in living cells. Journal of Cell Biology 1986, 103:2739-2746.
16. Dumont R., Okonkwo D., Verma S., Hurlbert R., Boulos P., Ellegala D., Dumont A. Acute spinal cord injury, part I: Pathophysiologic mechanisms. Clinical Neuropharmacology 2001, 24:254-264.
17. Faden A., Jacobs T., Patrick D., Smith M. Megadose corticosteroid therapy following experimental traumatic spinal injury. Journal of Neurosurgery 1984, 60:712-717.
18. Flanders A., Spettell C., Friedman D., Marino R., Herbison G. The relationship between the functional abilities of patients with cervical spinal cord injury and the severity of damage revealed by MR imaging. American Journal of Neuroradiology 1999, 20:926-934.
19. Georgieff I.S., Liem R., Couchie D., Mavilia C., Nunez J., Shelanski M.L. Expression of high molecular weight tau in the central and peripheral nervous systems. Journal of Cell Science 1993, 105:729.
20. Goedert M., Spillantini M., Jakes R., Rutherford D., Crowther R. Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 1989, 3:519-526.
21. Guéz M., Hildingsson C., Rosengren L., Karlsson K., Toolanen G. Nervous tissue damage markers in cerebrospinal fluid after cervical spine injuries and whiplash trauma. Journal of Neurotrauma 2003, 20:853-858.
22. Hanley J.A., McNeil B.J. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982, 143:29-36.
23. Head E., Moffat K., Das P., Sarsoza F., Poon W., Landsberg G., Cotman C.W., Murphy M. [beta]-Amyloid deposition and tau phosphorylation in clinically characterized aged cats. Neurobiology of Aging 2005, 26:749-763.
24. Ito D., Matsunaga S., Jeffery N., Sasaki N., Nishimura R., Mochizuki M., Kasahara M., Fujiwara R., Ogawa H. Prognostic value of magnetic resonance imaging in dogs with paraplegia caused by thoracolumbar intervertebral disk extrusion: 77 cases (2000-2003). Journal of the American Veterinary Medical Association 2005, 227:1454-1460.
25. Kearney P., Ridella S., Viano D., Anderson T. Interaction of contact velocity and cord compression in determining the severity of spinal cord injury. Journal of Neurotrauma 1988, 5:187-208.
26. Kwon B., Stammers A., Belanger L., Bernardo A., Chan D., Bishop C., Slobogean G., Zhang H., Umedaly H., Giffin M. Cerebrospinal fluid inflammatory cytokines and biomarkers of injury severity in acute human spinal cord injury. Journal of Neurotrauma 2010, 27:669-682.
27. Lachno D.R., Romeo M.J., Siemers E.R., Vanderstichele H., Coart E., Konrad R.J., Zajac J.J., Talbot J.A., Jensen H.F., Sethuraman G. Validation of ELISA methods for quantification of total tau and phosphorylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies. Journal of Alzheimer's Disease 2011, 26:531-541.
28. Levine J., Ruaux C., Bergman R., Coates J., Steiner J., Williams D. Matrix metalloproteinase-9 activity in the cerebrospinal fluid and serum of dogs with acute spinal cord trauma from intervertebral disk disease. American Journal of Veterinary Research 2006, 67:283-287.
29. Levine J., Fosgate G., Chen A., Rushing R., Nghiem P., Platt S., Bagley R., Kent M., Hicks D., Young B. Magnetic resonance imaging in dogs with neurologic impairment due to acute thoracic and lumbar intervertebral disk herniation. Journal of Veterinary Internal Medicine 2009, 23:1220-1226.
30. Levine G., Levine J., Witsberger T., Kerwin S., Russell K., Suchodolski J., Steiner J., Fosgate G. Cerebrospinal fluid myelin basic protein as a prognostic biomarker in dogs with thoracolumbar intervertebral disk herniation. Journal of Veterinary Internal Medicine 2010, 24:890-896.
31. Li M., Ona V.O., Chen M., Kaul M., Tenneti L., Zhang X., Stieg P.E., Lipton S.A., Friedlander R.M. Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury. Neuroscience 2000, 99:333-342.
32. Mori H., Hosoda K., Matsubara E., Nakamoto T., Furiya Y., Endoh R., Usami M., Shoji M., Maruyama S., Hirai S. Tau in cerebrospinal fluids: Establishment of the sandwich ELISA with antibody specific to the repeat sequence in tau. Neuroscience Letters 1995, 186:181-183.
33. Muñana K., Saito M., Hoshi F. Beta-2-microglobulin levels in the cerebrospinal fluid of normal dogs and dogs with neurological disease. Veterinary Clinical Pathology 2007, 36:173-178.
34. Nishimura T., Takeda M., Nakamura Y., Yosbida Y., Arai H., Sasaki H., Shouji M., Hirai S., Khise K., Tanaka K. Basic and clinical studies on the measurement of tau protein in cerebrospinal fluid as a biological marker for Alzheimer's disease and related disorders: Multicenter study in Japan. Methods and Findings in Experimental and Clinical Pharmacology 1998, 20:227-235.
35. Olby N. Current concepts in the management of acute spinal cord injury. Journal of Veterinary Internal Medicine 1999, 13:399-407.
36. Olby N., Sharp N., Muñana K., Papich M. Chronic and acute compressive spinal cord lesions in dogs due to intervertebral herniation are associated with elevation in lumbar cerebrospinal fluid glutamate concentration. Journal of Neurotrauma 1999, 16:1215-1224.
37. Pugliese M., Mascort J., Mahy N., Ferrer I. Diffuse beta-amyloid plaques and hyperphosphorylated tau are unrelated processes in aged dogs with behavioral deficits. Acta Neuropathologica 2006, 112:175-183.
38. Schoonenboom N., Mulder C., Vanderstichele H., Van Elk E., Kok A., Van Kamp G., Scheltens P., Blankenstein M. Effects of processing and storage conditions on amyloid beta (1-42) and tau concentrations in cerebrospinal fluid: Implications for use in clinical practice. Clinical Chemistry 2005, 51:189-195.
39. Schouman-Claeys E., Frija G., Cuenod C., Begon D., Paraire F., Martin V. MR imaging of acute spinal cord injury: Results of an experimental study in dogs. American Journal of Neuroradiology 1990, 11:959-965.
40. Segal M. Extracellular and cerebrospinal fluids. Journal of Inherited Metabolic Disease 1993, 16:617-638.
41. Sharp N.J.H., Wheeler S.J. Small Animal Spinal Disorders 2005, Elsevier Mosby, Edinburgh, London.
42. Shiiya N., Kunihara T., Miyatake T., Matsuzaki K., Yasuda K. Tau protein in the cerebrospinal fluid is a marker of brain injury after aortic surgery. Annals of Thoracic Surgery 2004, 77:2034-2038.
43. Sjögren M., Vanderstichele H., Agren H., Zachrisson O., Edsbagge M., Wikkelsø C., Skoog I., Wallin A., Wahlund L., Marcusson J. Tau and Aβ42 in cerebrospinal fluid from healthy adults 21-93 years of age: Establishment of reference values. Clinical Chemistry 2001, 47:1776-1781.
44. Srugo I., Aroch I., Christopher M.M., Chai O., Goralnik L., Bdolah-Abram T., Shamir M.H. Association of cerebrospinal fluid analysis findings with clinical signs and outcome in acute nonambulatory thoracolumbar disease in dogs. Journal of Veterinary Internal Medicine 2011, 25:846-855.
45. Swets J. Measuring the accuracy of diagnostic systems. Science 1988, 240:1285-1293.
46. Tanaka, N., Kitagawa, M., Ito, D., Okada, M., Ohta, S., Ono, K., Yamada, H., Watari, T., 2011. Measurement of tau protein levels in the cerebrospnal fluid of dogs with encephalitis. In: 24th Annual Symposium of the ECVN and ESVN ECC, Trier, Germany.
47. Terzi M., Birinci A., Cetinkaya E., Onar M. Cerebrospinal fluid total tau protein levels in patients with multiple sclerosis. Acta Neurologica Scandinavica 2007, 115:325-330.
48. Thomson C., Kornegay J., Stevens J. Canine intervertebral disease: Changes in the cerebrospinal fluid. Journal of Small Animal Practice 1989, 30:685-688.
49. Thomson C., Kornegay J., Stevens J. Analysis of cerebrospinal fluid from the cerebellomedullary and lumbar cisterns of dogs with focal neurologic disease: 145 cases (1985-1987). Journal of the American Veterinary Medical Association 1990, 196:1841-1844.
50. Vandermeeren M., Mercken M., Vanmechelen E., Six J., Voorde A., Martin J.J., Cras P. Detection of proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme linked immunosorbent assay. Journal of Neurochemistry 1993, 61:1828-1834.
51. Wang J.Z., Liu F. Microtubule-associated protein tau in development, degeneration and protection of neurons. Progress in Neurobiology 2008, 85:148-175.
52. Weingarten M., Lockwood A., Hwo S., Kirschner M. A protein factor essential for microtubule assembly. Proceedings of the National Academy of Sciences of the United States of America 1975, 72:1858-1862.
53. Witsberger T.H., Levine J.M., Fosgate G.T., Slater M.R., Kerwin S.C., Russell K.E., Levine G.J. Associations between cerebrospinal fluid biomarkers and long-term neurologic outcome in dogs with acute intervertebral disk herniation. Journal of the American Veterinary Medical Association 2012, 240:555-562.
54. Zemlan F., Rosenberg W.S., Luebbe P.A., Campbell T.A., Dean G.E., Weiner N.E., Cohen J.A., Rudick R.A., Woo D. Quantification of axonal damage in traumatic brain injury. Journal of Neurochemistry 1999, 72:741-750.