High performance collection of cerebrospinal fluid in rats: Evaluation of erythropoietin penetration after osmotic opening of the blood-brain barrier

Journal of Neuroscience Methods

Volumn 219, Issue 1, 2013, Pages 70-75

  Ceaglio, Natalia ^a   Orozco, Gustavo ^b   Etcheverrigaray, Marina ^a   Mattio, Mónica ^a   Kratje, Ricardo ^a   Perotti, Norma ^a   Oggero, Marcos ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

^b Zelltek SA Paraje El Pozo   (Argentina)

Author keywords

Blood brain barrier; Cerebrospinal fluid; Osmotic disruption; RhEPO; Sampling method

Indexed keywords

ADRENALIN; LIDOCAINE; RECOMBINANT ERYTHROPOIETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID EXAMINATION; CISTERNA MAGNA; CONTROLLED STUDY; COST CONTROL; DRUG PENETRATION; FEMALE; NONHUMAN; OSMOSIS; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SURVIVAL;

BLOOD-BRAIN BARRIER; CEREBROSPINAL FLUID; OSMOTIC DISRUPTION; RHEPO; SAMPLING METHOD;

ANIMALS; BLOOD-BRAIN BARRIER; CELL COUNT; CEREBROSPINAL FLUID; CISTERNA MAGNA; DATA INTERPRETATION, STATISTICAL; ERYTHROPOIETIN; FEMALE; GLOBULINS; INJECTIONS, INTRAVENOUS; MANNITOL; NECK; OSMOSIS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SKULL; SPECIMEN HANDLING;

EID: 84881646599     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2013.07.009     Document Type: Article

References (32)

1. Banks W.A., Jumbe N.L., Farrell C.L., Niehoff M.L., Heatherington A.C. Passage of erythropoietic agents across the blood-brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa. Eur J Pharmacol 2004, 505:93-101.
2. Bellavance M.A., Blanchette M., Fortin D. Recent advances in blood-brain barrier disruption as a CNS delivery strategy. AAPS J 2008, 10:166-177.
3. Bouman H.J., Van Wimersma Greidanus T.B. A rapid and simple cannulation technique for repeated sampling of cerebrospinal fluid in freely moving rats. Brain Res Bull 1979, 4:575-577.
4. Brines M.L., Ghezzi P., Keenan S., Agnello D., de Lanerolle N.C., Cerami C., et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA 2000, 97:10526-10531.
5. Consiglio A.R., Lucion A.B. Technique for collecting cerebrospinal fluid in the cisterna magna of non-anesthetized rats. Brain Res Brain Res Protoc 2000, 5:109-114.
6. De la Calle J.L., Paino C.L. A procedure for direct lumbar puncture in rats. Brain Res Bull 2002, 59:245-250.
7. Di L., Kerns E.H., Carter G.T. Strategies to assess blood-brain barrier penetration. Expert Opin Drug Discov 2008, 3:677-687.
8. Frankmann S.P. A technique for repeated sampling of CSF from the anesthetized rat. Physiol Behav 1986, 37:489-493.
9. Huang Y.L., Saljo A., Suneson A., Hansson H.A. A new approach for multiple sampling of cisternal cerebrospinal fluid in rodents with minimal trauma and inflammation. J Neurosci Methods 1995, 63:13-22.
10. Huang Y.L., Säljö A., Suneson A., Hansson H.A. Comparison among different approaches for sampling cerebrospinal fluid in rats. Brain Res Bull 1996, 41:273-279.
11. Kester M.I., Scheffer P.G., Koel-Simmelink M.J., Twaalfhoven H., Verwey N.A., Veerhuis R., et al. Serial CSF sampling in Alzheimer's disease: specific versus non-specific markers. Neurobiol Aging 2012, 33:1591-1598.
12. Mahat M.Y., Fakrudeen Ali Ahamed N., Chandrasekaran S., Rajagopal S., Narayanan S., Surendran N. An improved method of transcutaneous cisterna magna puncture for cerebrospinal fluid sampling in rats. J Neurosci Methods 2012, 211:272-279.
13. Mattio M., Ceaglio N., Oggero M., Perotti N., Amadeo I., Orozco G., et al. Isolation and characterization of a subset of erythropoietin glycoforms with cytoprotective but minimal erythropoietic activity. Biotechnol Progr 2011, 242:1018-1028.
14. Maurer T.S., Debartolo D.B., Tess D.A., Scott D.O. Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice. Drug Metab Dispos 2005, 33:175-181.
15. McCarty D.M., DiRosario J., Gulaid K., Muenzer J., Fu H. Mannitol-facilitated CNS entry of rAAV2 vector significantly delayed the neurological disease progression in MPS IIIB mice. Gene Ther 2009, 16:1340-1352.
16. National Research Council, Guide for the care and use of laboratory animals, Eight Edition, USA, 2010.
17. Nirogi R., Kandikere V., Mudigonda K., Bhyrapuneni G., Muddana N., Saralaya R., et al. A simple and rapid method to collect the cerebrospinal fluid of rats and its application for the assessment of drug penetration into the central nervous system. J Neurosci Methods 2009, 178:116-119.
18. Ohta M., Ohta K., Ma J., Takeuchi J., Saida T., Nishimura M., et al. Clinical and analytical evaluation of an enzyme immunoassay for myelin basic protein in cerebrospinal fluid. Clin Chem 2000, 46:1326-1330.
19. Patten B.M. How much blood makes the cerebrospinal fluid bloody?. J Am Med Assoc 1968, 206:378-379.
20. Pegg C.C., He C., Stroink A.R., Kattner K.A., Wang C.X. Technique for collection of cerebrospinal fluid from the cisterna magna in rat. J Neurosci Methods 2010, 187:8-12.
21. Rapoport S.I. Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications. Cell Mol Neurobiol 2000, 20:217-230.
22. Reichel A. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept. Chem Biodivers 2009, 6:2030-2049.
23. Sargin D., Friedrichs H., El-Kordi A., Ehrenreich H. Erythropoietin as neuroprotective and neuroregenerative treatment strategy: comprehensive overview of 12 years of preclinical and clinical research. Best Pract Res Clin Anaesthesiol 2010, 24:573-594.
24. Seyfried D.M., Han Y., Yang D., Ding J., Savant-Bhonsale S., Shukairy M.S., et al. Mannitol enhances delivery of marrow stromal cells to the brain after experimental intracerebral hemorrhage. Brain Res 2008, 1224:12-19.
25. Shen D.D., Artru A.A., Adkison K.K. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics. Adv Drug Deliv Rev 2004, 56:1825-1857.
26. Siren A.L., Fasshauer T., Bartels C., Ehrenreich H. Therapeutic potential of erythropoietin and its structural or functional variants in the nervous system. Neurotherapeutics 2009, 6:108-127.
27. Swartz C.M., Stenberg D. Quickly-made cannula for repeated cerebrospinal fluid sampling in rats. Commun Psychopharmacol 1980, 4:241-245.
28. Takasugi Y., Shirai T., Futagawa K., Koga Y., Egawa K., Watanabe S., et al. Transcutaneous cisternal puncture for sampling of cerebrospinal fluid in awake rat. Exp Anim 2005, 54:193-196.
29. van den Berg M.P., Romeijn S.G., Verhoef J.C., Merkus F.W. Serial cerebrospinal fluid sampling in a rat model to study drug uptake from the nasal cavity. J Neurosci Methods 2002, 116:99-107.
30. Wang X., Kimura S., Yazawa T., Endo N. Cerebrospinal fluid sampling by lumbar puncture in rats - repeated measurements of nitric oxide metabolites. J Neurosci Methods 2005, 145:89-95.
31. Yang J., Wadghiri Y.Z., Hoang D.M., Tsui W., Sun Y., Chung E., et al. Detection of amyloid plaques targeted by USPIO-Abeta1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging. Neuroimage 2011, 55:1600-1609.
32. Ylitalo P., Heikkinen E.R., Myllylä V.V. Evaluation of successive collections of cisternal cerebrospinal fluid in rats, rabbits, and cats. Exp Neurol 1976, 50:330-336.