Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 305, Issue 4, 2013, Pages

  Dai, Fei ^a   Lei, Yong ^a   Li, Shiying ^a   Song, Gengqing ^a   Chen, Jiande D Z ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b Ningbo Pace Translational Medical Research Center   (China)

Author keywords

Antidepressant; Desvenlafaxine succinate; Gastric emptying; Visceral hypersensitivity

Indexed keywords

ACETIC ACID; DESVENLAFAXINE; KETANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAM; GASTROINTESTINAL DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH DISTENSION; STOMACH EMPTYING; VISCERAL HYPERSENSITIVITY;

ANTIDEPRESSANT; DESVENLAFAXINE SUCCINATE; GASTRIC EMPTYING; VISCERAL HYPERSENSITIVITY;

ACETIC ACID; ADMINISTRATION, ORAL; ADRENERGIC UPTAKE INHIBITORS; ANIMALS; CYCLOHEXANOLS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROMYOGRAPHY; GASTRIC EMPTYING; GASTROPARESIS; HYPERALGESIA; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SUBCUTANEOUS; MALE; MECHANOTRANSDUCTION, CELLULAR; NOREPINEPHRINE; PAIN MEASUREMENT; PAIN THRESHOLD; PRESSURE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS; STOMACH; STOMACH ULCER;

EID: 84881625207     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00224.2012     Document Type: Article

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