In Search of an Adult Attachment Stress Provocation to Measure Effect on the Oxytocin System: A Pilot Validation Study

Journal of the American Psychiatric Nurses Association

Volumn 19, Issue 4, 2013, Pages 180-191

  Munro, Michelle L ^a   Brown, Stephanie L ^b   Pournajafi Nazarloo, Hossein ^c   Carter, C Sue ^c   Lopez, William D ^a   Seng, Julia S ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

attachment; biomarker; dissociation; oxytocin; posttraumatic stress disorder (PTSD)

Indexed keywords

BIOLOGICAL MARKER; OXYTOCIN;

ADOLESCENT; ADULT; AROUSAL; ARTICLE; ATTACHMENT; BLOOD; DISSOCIATION; DISSOCIATIVE DISORDER; FEMALE; HUMAN; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MENTAL STRESS; NURSING; OBJECT RELATION; PATHOPHYSIOLOGY; PHYSIOLOGY; PILOT STUDY; POSTTRAUMATIC STRESS DISORDER; PSYCHOLOGICAL ASPECT; PSYCHOSOCIAL DISORDER; REFERENCE VALUE; SOMATOFORM DISORDER; STATISTICS; STUDENT; VALIDATION STUDY; YOUNG ADULT;

ATTACHMENT; BIOMARKER; DISSOCIATION; OXYTOCIN; POSTTRAUMATIC STRESS DISORDER (PTSD);

ADOLESCENT; ADULT; AROUSAL; BIOLOGICAL MARKERS; DISSOCIATIVE DISORDERS; FEMALE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; OBJECT ATTACHMENT; OXYTOCIN; PILOT PROJECTS; PITUITARY-ADRENAL SYSTEM; REACTIVE ATTACHMENT DISORDER; REFERENCE VALUES; SOMATOFORM DISORDERS; STATISTICS AS TOPIC; STRESS DISORDERS, POST-TRAUMATIC; STRESS, PSYCHOLOGICAL; STUDENTS; YOUNG ADULT;

EID: 84881590116     PISSN: 10783903     EISSN: 15325725     Source Type: Journal    
DOI: 10.1177/1078390313492173     Document Type: Article

References (59)

1. Ainsworth M. D. S.Object relations, dependency, and attachment: A theoretical review of the infant-mother relationship.Child Development. 1969;40:969-1025.
2. Ainsworth M. D. S.Patterns of infant-mother attachments: Antecedents and effects on development.New York Academy of Medicine. 1985;61:771-791.
3. Diagnostic and statistical manual of mental disorders. 1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.Washington, DC: Author; 1994:.
4. Bartz J. A.,Hollander E.The neuroscience of affiliation: Forging links between basic and clinical research on neuropeptides and social behavior.Hormones and Behavior. 2006;50:518-528.
5. Beck A. T.,Steer R. A.,Garbin M. G.Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation.Clinical Psychology Review. 1988;8:77-100.
6. Beck A. T.,Ward C. H.,Mendelson M.,Mock J.,Erbaugh J.An inventory for measuring depression.Archives of General Psychiatry. 1961;4:561-571.
7. Blanchard E. B.,Jones-Alexander J.,Buckley T. C.,Forneris C. A.Psychometric properties of the PTSD Checklist (PCL).Behavior Research Therapy. 1996;34:669-673.
8. Carter C. S.Neuroendocrine perspectives on social attachment and love.Psychoneuroendocrinology. 1998;23:779-818.
9. Carter C. S.,Boone E. M.,Pournajafi-Nazarloo H.,Bales K. L.Consequences of early experiences and exposure to oxytocin and vasopressin are sexually dimporphic.Developmental Neuroscience. 2009;31:332-341.
10. Carter C. S.,Porges S. W.Encyclopedia of behavioral neuroscience. Koob G.Le Moal M.Thompson R., ed. New York, NY: Elsevier; 2010:257-262.
11. Carter C. S.,Pournajafi-Nazarloo H.,Kramer K. M.,Ziegler T. E.,White-Traut R.,Bello D.,Schwertz D.Oxytocin: Behavioral associations and potential as a salivary biomarker.Annals of the New York Academy of Sciences. 2007;1098:312-322.
12. Cyranowski J. M.,Hofkins T. L.,Frank E.,Seltman H.,Cai H. M.,Amico J. A.Evidence of dysregulated peripheral oxytocin regulation among depressed women.Psychosomatic Medicine. 2008;70:967-975.
13. Derogatis L. R.,Lipman R. S.,Covi L.The SCL-90: An outpatient psychiatric rating scale.Psychopharmacology Bulletin. 1973;9:13-28.
14. Derogatis L. R.,Rickels K.,Rock A. F.The SCL-90 and the MMPI: A step in the validation of a new self-report scale.British Journal of Psychiatry. 1976;128:280-289.
15. Diamond L. M.Contributions of psychophysiology to research on adult attachment: Review and recommendations.Personality and Social Psychology Review. 2001;5:276-295.
16. Drago F.,Pedersen C. A.,Caldwell J. D.,Prange A. J.Oxytocin potently enhances novelty-induced grooming behavior in the rat.Brain Research. 1986;368:287-295.
17. Feldman R.,Gordon I.,Influs M.,Gutbir T.,Ebstein R. P.Parental oxytocin and early caregiving jointly shape children's oxytocin responses and social reciprocity.Neuropsychopharmacology. 2013;:.
18. Feldman R.,Gordon I.,Schneiderman I.,Weisman O.,Zagoory-Sharon O.Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact.Psychoneuroendocrinology. 2010;35:1133-1141.
19. Ferguson J. N.,Young L. J.,Hearn E. F.,Matzuk M. M.,Insel T. R.,Winslow J. T.Social amnesia in mice lacking the oxytocin gene.Nature Genetics. 2000;25:284-288.
20. Fredrickson B. L.,Mancuso R. A.,Branigan C.,Tugade M. M.The undoing effect of positive emotions.Motivation and Emotion. 2000;24:237-258.
21. Freyd J. J.Betrayal trauma: The logic of forgetting childhood abuse. Cambridge, MA: Harvard University Press; 1996:.
22. Gordon I.,Zagoory-Sharon O.,Schneiderman I.,Leckman J. F.,Weller A.,Feldman R.Oxytocin and cortisol in romantically unattached adults: Associations with bonding and psychological distress.Psychophysiology. 2008;45:349-352.
23. Gouin J.,Carter C. S.,Pournajafi-Nazarloo H.,Glaser R.,Malarkey W. B.,Loving T. J.,Kiecolt-Glaser J. K.Marital behavior, oxytocin, vasopressin, and wound healing.Psychoneuroendocrinology. 2010;35:1082-1090.
24. Heinrichs M.,von Dawans B.,Domes G.Oxytocin, vasopressin, and human social behavior.Frontiers in Neuroendocrinology. 2009;30:548-557.
25. Herman J. L.Complex PTSD: A syndrome in survivors of prolonged and repeated trauma.Journal of Traumatic Stress. 1992;5:377-391.
26. Herman J. L.Trauma and recovery. New York, NY: Basic Books; 1997:.
27. Insel T. R.,Hulihan T. J.A gender-specific mechanism for pair bonding: Oxytocin and partner preference formation in monogamous voles.Behavioral Neuroscience. 1995;109:782-789.
28. Keverne E. B.,Nevison C. M.,Martel F. L.Early learning and the social bond.Annals of the New York Academy of Science. 1997;807:329-339.
29. Kilpatrick D. G.,Resnick H. S.,Freedy J. R.,Pelcovitz D.,Resick P. A.,Roth S.,van der Kolk B.DSM-IV sourcebook. Widiger T. A.Frances A. J.Pincus H. A.Ross R.First M. B.Davis W.Kline M., ed. Washington, DC: American Psychiatric Press; 1998:803-838.
30. Lanius R. A.,Vermetten E.,Loewenstein R. J.,Brand B.,Schmahl C.,Bremner D.,Spiegel D.Emotion modulation in PTSD: Clinical and neurobiological evidence for a dissociative subtype.American Journal of Psychiatry. 2010;167:640-647.
31. Maes M.,Lin A. H.,Bonaccorso S.,Goossens F.,Van Gastel A.,Pioli R.,Scharpé S. J.Higher serum prolyl endopeptidase activity in patients with post-traumatic stress disorder.Journal of Affective Disorders. 1999;53:27-34.
32. McCarthy M. M.,Kow L. M.,Pfaff D. W.Speculations concerning the physiological significance of central oxytocin in maternal behavior.Annals of the New York Academy of Sciences. 1992;652:70-82.
33. Meaney M. J.Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations.Annual Review of Neuroscience. 2001;24:1161-1192.
34. Meewisse M. L.,Reitsma J. B.,de Vries G. J.,Gersons B. P.,Olff M.Cortisol and post-traumatic stress disorder in adults: Systematic review and meta-analysis.British Journal of Psychiatry. 2007;191:387-392.
35. Panksepp J.,Nelson E.,Bekkedal M.Brain systems for the mediation of social separation-distress and social-reward evolutionary antecedents and neuropeptide intermediaries.Annals of the New York Academy of Sciences. 2006;807:78-100.
36. Pedersen C. A.Oxytocin control of maternal behavior: Regulation by sex steroids and offspring stimuli.Annals of the New York Academy of Sciences. 1997;807:126-145.
37. Pedersen C. A.,Prange A. J.Induction of maternal behavior in virgin rats after intracerebroventricular administration of oxytocin.Proceedings of the National Academy of Sciences. 1979;76:6661-6665.
38. Pierrehumbert B.,Torrisi R.,Ansermet F.,Borghini A.,Halfon O.Adult attachment representations predict cortisol and oxytocin responses to stress.Attachment & Human Development. 2012;14:453-476.
39. Pierrehumbert B.,Torrisi R.,Laufer D.,Halfon O.,Ansermet F.,Beck Popovic M.Oxytocin response to an experimental psychosocial challenge in adults exposed to traumatic experiences during childhood or adolescence.Neuroscience. 2010;166:168-177.
40. Porges S. W.The polyvagal theory. New York, NY: W. W. Norton; 2011:.
41. Ruggiero K. J.,Del Ben K.,Scotti J. R.,Rabalais A. E.Psychometric properties of the PTSD Checklist-Civilian Version.Journal of Traumatic Stress. 2003;16:495-502.
42. Schore A. N.Affect dysregulation and disorders of the self. New York, NY: W. W. Norton; 2003:.
43. Seng J.Is posttraumatic oxytocin dysregulation a link among posttraumatic self disorders, posttraumatic stress disorder, and pelvic visceral dysregulation conditions in women?.Journal of Trauma and Dissociation. 2010;11:387-406.
44. Seng J. S.,D'Andrea W.,Ford J. D.Complex mental health sequelae of psychological trauma among women in prenatal care.Psychological Trauma: Research Theory, Practice, and Policy. 2013;:.
45. Seng J. S.,Miller J. M.,Sperlich M.,van de,Ven C. J. M.,Brown S. B.,Carter S. C.,Liberzon I.Exploring dissociation and oxytocin as pathways between trauma exposure and trauma-related hyperemesis gravidarum: A test-of-concept pilot.Journal of Trauma & Dissociation. 2013;14:40-55.
46. Skrundz M.,Bolten M.,Nast I.,Hellhammer D. H.,Meinlschmidt G.Plasma oxytocin concentration during pregnancy is associated with development of postpartum depression.Neuropsychopharmacology. 2011;36:1886-1893.
47. Stein D. J.,Koenen K. C.,Friedman M. J.,Hill E.,McLaughlin K. A,Petukhova M.,Kessler R. C.Dissociation in posttraumatic stress disorder: Evidence from the world mental health surveys.Biological Psychiatry. 2012;:.
48. Taylor S. E.Tend and befriend: Biobehavioral bases of affiliation under stress.Current Directions in Psychological Science. 2006;15:273-277.
49. Teicher M. H.,Andersen S. L.,Polcari A.,Anderson C. M.,Navalta C. P.Developmental neurobiology of childhood stress and trauma.Psychiatric Clinics of North America. 2002;25:397-426.
50. Trickett P. K.,Noll J. G.,Susman E. J.,Shenk C. E.,Putnam F. W.Attenuation of cortisol across development for victims of sexual abuse.Development and Psychopathology. 2010;22:165-175.
51. Uvnas-Moberg K.The oxytocin factor: Tapping the hormone of calm, love, and healing. Cambridge, MA: Da Capo Press; 2003:.
52. van der Kolk B. A.Developmental trauma disorder.Psychiatric Annals. 2005;35:401-408.
53. Waller N. G.,Putnam F. W.,Carlson E. B.Dissociation and dissociative types: A taxometric analysis of dissociative experiences.Psychological Methods. 1996;1:300-321.
54. Waller N. G.,Ross C. A.The prevalence and biometric structure of pathological dissociation in the general population: Taxometric and behavior genetic findings.Journal of Abnormal Psychology. 1997;106:499-510.
55. Weathers F. W.,Litz B. T.,Herman D. S.,Huska J. A.,Keane T. M. Paper presented at the annual meeting of the International Society for Traumatic Stress Studies; 1993San Antonio, TX; 1993.
56. Williams J. R.,Insel T. R.,Harbaugh C. R.,Carter C. S.Oxytocin administered centrally facilitates formation of a partner preference in female prairie voles (Microtus ochrogaster).Journal of Neuroendocrinology. 1994;6:247-250.
57. Wirth M. M.,Schultheiss O. C.Effects of affiliation arousal (hope of closeness) and affiliation stress (fear of rejection) on progesterone and cortisol.Hormones and Behavior. 2006;50:786-795.
58. Wolf E. J.,Miller M. W.,Reardon A. F.,Ryabchenko K. A.,Castillo D.,Freund R.A latent class analysis of dissociation and PTSD: Evidence for a dissociative subtype.Archives of General Psychiatry. 2012;69:698-705.
59. Wolfe J.,Kimmerling R.Assessing psychological trauma and PTSD. Wilson J. P.Keane T. M., ed. New York, NY: Guilford Press; 1997:192-238.