메뉴 건너뛰기




Volumn 2013, Issue 2, 2013, Pages

UNC-13L, UNC-13S, and Tomosyn form a protein code for fast and slow neurotransmitter release in Caenorhabditis elegans

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CAENORHABDITIS ELEGANS PROTEIN; CALCIUM CHANNEL; CALMODULIN; CHOLINERGIC RECEPTOR; TOMOSYN; UNC 13L PROTEIN; UNC 13S PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; ISOPROTEIN; PHORBOL ESTER BINDING PROTEIN; TOM-1 PROTEIN, C ELEGANS;

EID: 84881583312     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.00967     Document Type: Article
Times cited : (74)

References (38)
  • 1
    • 0029835618 scopus 로고    scopus 로고
    • Determinants of the time course of facilitation at the granule cell to Purkinje cell synapse
    • Atluri PP, Regehr WG. 1996. Determinants of the time course of facilitation at the granule cell to Purkinje cell synapse. J Neurosci 16:5661-71.
    • (1996) J Neurosci , vol.16 , pp. 5661-5671
    • Atluri, P.P.1    Regehr, W.G.2
  • 2
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. 1974. The genetics of Caenorhabditis elegans. Genetics 77:71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 3
    • 0034082054 scopus 로고    scopus 로고
    • Regulation of transmitter release by Unc-13 and its homologues
    • doi: 10.1016/S0959-4388(00)00105-7
    • Brose N, Rosenmund C, Rettig J. 2000. Regulation of transmitter release by Unc-13 and its homologues. Curr Opin Neurobiol 10:303-11. doi: 10.1016/S0959-4388(00)00105-7.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 303-311
    • Brose, N.1    Rosenmund, C.2    Rettig, J.3
  • 4
    • 46449093538 scopus 로고    scopus 로고
    • How does synaptotagmin trigger neurotransmitter release?
    • doi: 10.1146/annurev.biochem.77.062005.101135
    • Chapman ER. 2008. How does synaptotagmin trigger neurotransmitter release? Annu Rev Biochem 77:615-41. doi: 10.1146/annurev.biochem.77.062005.101135.
    • (2008) Annu Rev Biochem , vol.77 , pp. 615-641
    • Chapman, E.R.1
  • 5
    • 84877244766 scopus 로고    scopus 로고
    • The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse
    • doi: 10.1523/JNEUROSCI.5128-12.2013
    • Chen Z, Cooper B, Kalla S, Varoqueaux F, Young SM Jnr. 2013. The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse. J Neurosci 33:8336-51. doi: 10.1523/JNEUROSCI.5128-12.2013.
    • (2013) J Neurosci , vol.33 , pp. 8336-8351
    • Chen, Z.1    Cooper, B.2    Kalla, S.3    Varoqueaux, F.4    Young Jr., S.M.5
  • 6
    • 57149117136 scopus 로고    scopus 로고
    • Profiling synaptic proteins identifies regulators of insulin secretion and lifespan
    • doi: 10.1371/journal.pgen.1000283
    • Ch'ng Q, Sieburth D, Kaplan JM. 2008. Profiling synaptic proteins identifies regulators of insulin secretion and lifespan. PLOS Genet 4:e1000283. doi: 10.1371/journal.pgen.1000283.
    • (2008) PLOS Genet , vol.4
    • Ch'ng, Q.1    Sieburth, D.2    Kaplan, J.M.3
  • 7
    • 0033568876 scopus 로고    scopus 로고
    • Measurement of action potential-induced presynaptic calcium domains at a cultured neuromuscular junction
    • DiGregorio DA, Peskoff A, Vergara JL. 1999. Measurement of action potential-induced presynaptic calcium domains at a cultured neuromuscular junction. J Neurosci 19:7846-59.
    • (1999) J Neurosci , vol.19 , pp. 7846-7859
    • DiGregorio, D.A.1    Peskoff, A.2    Vergara, J.L.3
  • 8
    • 33746627569 scopus 로고    scopus 로고
    • Factors regulating the abundance and localization of synaptobrevin in the plasma membrane
    • doi: 10.1073/pnas.0600784103
    • Dittman JS, Kaplan JM. 2006. Factors regulating the abundance and localization of synaptobrevin in the plasma membrane. Proc Natl Acad Sci USA 103:11399-404. doi: 10.1073/pnas.0600784103.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11399-11404
    • Dittman, J.S.1    Kaplan, J.M.2
  • 9
    • 49049088584 scopus 로고    scopus 로고
    • Behavioral impact of neurotransmitter-gated GPCRs: Muscarinic and GABAB receptors regulate C. elegans locomotion
    • doi: 10.1523/JNEUROSCI.0378-08.2008
    • Dittman JS, Kaplan JM. 2008. Behavioral impact of neurotransmitter-gated GPCRs: muscarinic and GABAB receptors regulate C. elegans locomotion. J Neurosci 28:7104-12. doi: 10.1523/JNEUROSCI.0378-08.2008.
    • (2008) J Neurosci , vol.28 , pp. 7104-7112
    • Dittman, J.S.1    Kaplan, J.M.2
  • 10
    • 20444417496 scopus 로고    scopus 로고
    • The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction
    • doi: 10.1016/j.neuron.2005.04.010
    • Francis MM, Evans SP, Jensen M, Madsen DM, Mancuso J, Norman KR, et al. 2005. The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction. Neuron 46:581-94. doi: 10.1016/j.neuron.2005.04.010.
    • (2005) Neuron , vol.46 , pp. 581-594
    • Francis, M.M.1    Evans, S.P.2    Jensen, M.3    Madsen, D.M.4    Mancuso, J.5    Norman, K.R.6
  • 12
  • 13
    • 51349162914 scopus 로고    scopus 로고
    • Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density
    • doi: 10.1016/j.neulet.2008.08.026
    • Gracheva EO, Hadwiger G, Nonet ML, Richmond JE. 2008. Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density. Neurosci Lett 444:137-42. doi: 10.1016/j.neulet.2008.08.026.
    • (2008) Neurosci Lett , vol.444 , pp. 137-142
    • Gracheva, E.O.1    Hadwiger, G.2    Nonet, M.L.3    Richmond, J.E.4
  • 15
    • 78651481610 scopus 로고    scopus 로고
    • RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone
    • doi: 10.1016/j.neuron.2010.12.014
    • Han Y, Kaeser PS, Sudhof TC, Schneggenburger R. 2011. RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone. Neuron 69:304-16. doi: 10.1016/j.neuron.2010.12.014.
    • (2011) Neuron , vol.69 , pp. 304-316
    • Han, Y.1    Kaeser, P.S.2    Sudhof, T.C.3    Schneggenburger, R.4
  • 16
    • 84865287380 scopus 로고    scopus 로고
    • Neurexin and neuroligin mediate retrograde synaptic inhibition in C. elegans
    • doi: 10.1126/science.1224896
    • Hu Z, Hom S, Kudze T, Tong XJ, Choi S, Aramuni G, et al. 2012. Neurexin and neuroligin mediate retrograde synaptic inhibition in C. elegans. Science 337:980-4. doi: 10.1126/science.1224896.
    • (2012) Science , vol.337 , pp. 980-984
    • Hu, Z.1    Hom, S.2    Kudze, T.3    Tong, X.J.4    Choi, S.5    Aramuni, G.6
  • 17
    • 4043075637 scopus 로고    scopus 로고
    • Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity
    • doi: 10.1016/j.cell.2004.06.029
    • Junge HJ, Rhee JS, Jahn O, Varoqueaux F, Spiess J, Waxham MN, et al. 2004. Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity. Cell 118:389-401. doi: 10.1016/j.cell.2004.06.029.
    • (2004) Cell , vol.118 , pp. 389-401
    • Junge, H.J.1    Rhee, J.S.2    Jahn, O.3    Varoqueaux, F.4    Spiess, J.5    Waxham, M.N.6
  • 18
    • 78651509693 scopus 로고    scopus 로고
    • RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction
    • doi: 10.1016/j.cell.2010.12.029
    • Kaeser PS, Deng L, Wang Y, Dulubova I, Liu X, Rizo J, et al. 2011. RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell 144:282-95. doi: 10.1016/j.cell.2010.12.029.
    • (2011) Cell , vol.144 , pp. 282-295
    • Kaeser, P.S.1    Deng, L.2    Wang, Y.3    Dulubova, I.4    Liu, X.5    Rizo, J.6
  • 19
    • 0033790323 scopus 로고    scopus 로고
    • Expression of multiple UNC-13 proteins in the C. elegans nervous system
    • Kohn R, Duerr J, McManus J, Duke A, Rakow T, Maruyama H, et al. 2000. Expression of multiple UNC-13 proteins in the C. elegans nervous system. Mol Biol Cell 11:3441-52.
    • (2000) Mol Biol Cell , vol.11 , pp. 3441-3452
    • Kohn, R.1    Duerr, J.2    McManus, J.3    Duke, A.4    Rakow, T.5    Maruyama, H.6
  • 20
    • 84868688514 scopus 로고    scopus 로고
    • Non-conserved Ca2+/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity
    • doi: 10.1128/MCB.00933-12
    • Lipstein N, Schaks S, Dimova K, Kalkhof S, Ihling C, Kolbel K, et al. 2012. Non-conserved Ca2+/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity. Mol Cell Biol 32:4628-41. doi: 10.1128/MCB.00933-12.
    • (2012) Mol Cell Biol , vol.32 , pp. 4628-4641
    • Lipstein, N.1    Schaks, S.2    Dimova, K.3    Kalkhof, S.4    Ihling, C.5    Kolbel, K.6
  • 21
    • 22544446151 scopus 로고    scopus 로고
    • Presynaptic ryanodine receptors are required for normal quantal size at the Caenorhabditis elegans neuromuscular junction
    • doi: 10.1523/JNEUROSCI.1730-05.2005
    • Liu Q, Chen B, Yankova M, Morest DK, Maryon E, Hand AR, et al. 2005. Presynaptic ryanodine receptors are required for normal quantal size at the Caenorhabditis elegans neuromuscular junction. J Neurosci 25:6745-54. doi: 10.1523/JNEUROSCI.1730-05.2005.
    • (2005) J Neurosci , vol.25 , pp. 6745-6754
    • Liu, Q.1    Chen, B.2    Yankova, M.3    Morest, D.K.4    Maryon, E.5    Hand, A.R.6
  • 22
    • 67649770501 scopus 로고    scopus 로고
    • Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction
    • doi: 10.1073/pnas.0903570106
    • Liu Q, Hollopeter G, Jorgensen EM. 2009. Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction. Proc Natl Acad Sci USA 106:10823-8. doi: 10.1073/pnas.0903570106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 10823-10828
    • Liu, Q.1    Hollopeter, G.2    Jorgensen, E.M.3
  • 23
    • 33745878240 scopus 로고    scopus 로고
    • Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch
    • doi: 10.1371/journal.pbio.0040192
    • Lu J, Machius M, Dulubova I, Dai H, Sudhof TC, Tomchick DR, et al. 2006. Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch. PLOS Biol 4:e192. doi: 10.1371/journal.pbio.0040192.
    • (2006) PLOS Biol , vol.4
    • Lu, J.1    McHius, M.2    Dulubova, I.3    Dai, H.4    Sudhof, T.C.5    Tomchick, D.R.6
  • 24
    • 29044447583 scopus 로고    scopus 로고
    • UNC-13 interaction with syntaxin is required for synaptic transmission
    • doi: 10.1016/j.cub.2005.10.049
    • Madison JM, Nurrish S, Kaplan JM. 2005. UNC-13 interaction with syntaxin is required for synaptic transmission. Curr Biol 15:2236-42. doi: 10.1016/j.cub.2005.10.049.
    • (2005) Curr Biol , vol.15 , pp. 2236-2242
    • Madison, J.M.1    Nurrish, S.2    Kaplan, J.M.3
  • 25
    • 33746726458 scopus 로고    scopus 로고
    • Antagonistic regulation of synaptic vesicle priming by Tomosyn and UNC-13
    • doi: 10.1016/j.neuron.2006.06.025
    • McEwen JM, Madison JM, Dybbs M, Kaplan JM. 2006. Antagonistic regulation of synaptic vesicle priming by Tomosyn and UNC-13. Neuron 51:303-15. doi: 10.1016/j.neuron.2006.06.025.
    • (2006) Neuron , vol.51 , pp. 303-315
    • McEwen, J.M.1    Madison, J.M.2    Dybbs, M.3    Kaplan, J.M.4
  • 26
    • 84870044610 scopus 로고    scopus 로고
    • RIM controls homeostatic plasticity through modulation of the readily-releasable vesicle pool
    • doi: 10.1523/JNEUROSCI.0981-12.2012
    • Müller M, Liu KS, Sigrist SJ, Davis GW. 2012. RIM controls homeostatic plasticity through modulation of the readily-releasable vesicle pool. J Neurosci 32:16574-85. doi: 10.1523/JNEUROSCI.0981-12.2012.
    • (2012) J Neurosci , vol.32 , pp. 16574-16585
    • Müller, M.1    Liu, K.S.2    Sigrist, S.J.3    Davis, G.W.4
  • 27
    • 52049106127 scopus 로고    scopus 로고
    • Multiple roles of calcium ions in the regulation of neurotransmitter release
    • doi: 10.1016/j.neuron.2008.08.019
    • Neher E, Sakaba T. 2008. Multiple roles of calcium ions in the regulation of neurotransmitter release. Neuron 59:861-72. doi: 10.1016/j.neuron.2008.08.019.
    • (2008) Neuron , vol.59 , pp. 861-872
    • Neher, E.1    Sakaba, T.2
  • 28
    • 0033198830 scopus 로고    scopus 로고
    • Serotonin inhibition of synaptic transmission: GOA-1 decreases the abundance of UNC-13 at release sites
    • doi: 10.1016/S0896-6273(00)80835-1
    • Nurrish S, Segalat L, Kaplan J. 1999. Serotonin inhibition of synaptic transmission: GOA-1 decreases the abundance of UNC-13 at release sites. Neuron 24:231-42. doi: 10.1016/S0896-6273(00)80835-1.
    • (1999) Neuron , vol.24 , pp. 231-242
    • Nurrish, S.1    Segalat, L.2    Kaplan, J.3
  • 29
    • 77955057373 scopus 로고    scopus 로고
    • Cell biology of Ca2+-triggered exocytosis
    • doi: 10.1016/j.ceb.2010.05.001
    • Pang ZP, Sudhof TC. 2010. Cell biology of Ca2+-triggered exocytosis. Curr Opin Cell Biol 22:496-505. doi: 10.1016/j.ceb.2010.05.001.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 496-505
    • Pang, Z.P.1    Sudhof, T.C.2
  • 30
    • 0033349884 scopus 로고    scopus 로고
    • UNC-13 is required for synaptic vesicle fusion in C. elegans
    • doi: 10.1038/14755
    • Richmond JE, Davis WS, Jorgensen EM. 1999. UNC-13 is required for synaptic vesicle fusion in C. elegans. Nat Neurosci 2:959-64. doi: 10.1038/14755.
    • (1999) Nat Neurosci , vol.2 , pp. 959-964
    • Richmond, J.E.1    Davis, W.S.2    Jorgensen, E.M.3
  • 31
    • 76349121068 scopus 로고    scopus 로고
    • Modular architecture of Munc13/calmodulin complexes: Dual regulation by Ca2+ and possible function in short-term synaptic plasticity
    • doi: 10.1038/emboj.2009.373
    • Rodriguez-Castaneda F, Maestre-Martinez M, Coudevylle N, Dimova K, Junge H, Lipstein N, et al. 2010. Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. EMBO J 29:680-91. doi: 10.1038/emboj.2009.373.
    • (2010) EMBO J , vol.29 , pp. 680-691
    • Rodriguez-Castaneda, F.1    Maestre-Martinez, M.2    Coudevylle, N.3    Dimova, K.4    Junge, H.5    Lipstein, N.6
  • 32
    • 0030175394 scopus 로고    scopus 로고
    • Definition of the readily releasable pool of vesicles at hippocampal synapses
    • doi: 10.1016/S0896-6273(00)80146-4
    • Rosenmund C, Stevens CF. 1996. Definition of the readily releasable pool of vesicles at hippocampal synapses. Neuron 16:1197-207. doi: 10.1016/S0896-6273(00)80146-4.
    • (1996) Neuron , vol.16 , pp. 1197-1207
    • Rosenmund, C.1    Stevens, C.F.2
  • 33
    • 67649871266 scopus 로고    scopus 로고
    • A common molecular basis for membrane docking and functional priming of synaptic vesicles
    • doi: 10.1111/j.1460-9568.2009.06811.x
    • Siksou L, Varoqueaux F, Pascual O, Triller A, Brose N, Marty S. 2009. A common molecular basis for membrane docking and functional priming of synaptic vesicles. Eur J Neurosci 30:49-56. doi: 10.1111/j.1460-9568.2009.06811.x.
    • (2009) Eur J Neurosci , vol.30 , pp. 49-56
    • Siksou, L.1    Varoqueaux, F.2    Pascual, O.3    Triller, A.4    Brose, N.5    Marty, S.6
  • 34
    • 22844452091 scopus 로고    scopus 로고
    • Acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction
    • doi: 10.1074/jbc.M502818200
    • Touroutine D, Fox RM, Von Stetina SE, Burdina A, Miller DM III, Richmond JE. 2005. acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction. J Biol Chem 280:27013-21. doi: 10.1074/jbc.M502818200.
    • (2005) J Biol Chem , vol.280 , pp. 27013-27021
    • Touroutine, D.1    Fox, R.M.2    von Stetina, S.E.3    Burdina, A.4    Miller III, D.M.5    Richmond, J.E.6
  • 35
    • 49749084725 scopus 로고    scopus 로고
    • Vesicle docking in regulated exocytosis
    • doi: 10.1111/j.1600-0854.2008.00759.x
    • Verhage M, Sorensen JB. 2008. Vesicle docking in regulated exocytosis. Traffic 9:1414-24. doi: 10.1111/j.1600-0854.2008.00759.x.
    • (2008) Traffic , vol.9 , pp. 1414-1424
    • Verhage, M.1    Sorensen, J.B.2
  • 36
    • 33748129499 scopus 로고    scopus 로고
    • UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains
    • doi: 10.1523/JNEUROSCI.2350-06.2006
    • Weimer RM, Gracheva EO, Meyrignac O, Miller KG, Richmond JE, Bessereau JL. 2006. UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains. J Neurosci 26:8040-7. doi: 10.1523/JNEUROSCI.2350-06.2006.
    • (2006) J Neurosci , vol.26 , pp. 8040-8047
    • Weimer, R.M.1    Gracheva, E.O.2    Meyrignac, O.3    Miller, K.G.4    Richmond, J.E.5    Bessereau, J.L.6
  • 37
    • 80155205418 scopus 로고    scopus 로고
    • Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release
    • doi: 10.1016/j.cell.2011.09.046
    • Yao J, Gaffaney JD, Kwon SE, Chapman ER. 2011. Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release. Cell 147:666-77. doi: 10.1016/j.cell.2011.09.046.
    • (2011) Cell , vol.147 , pp. 666-677
    • Yao, J.1    Gaffaney, J.D.2    Kwon, S.E.3    Chapman, E.R.4
  • 38
    • 0036201201 scopus 로고    scopus 로고
    • Short-term synaptic plasticity
    • doi: 10.1146/annurev.physiol.64.092501.114547
    • Zucker RS, Regehr WG. 2002. Short-term synaptic plasticity. Annu Rev Physiol 64:355-405. doi: 10.1146/annurev.physiol.64.092501.114547.
    • (2002) Annu Rev Physiol , vol.64 , pp. 355-405
    • Zucker, R.S.1    Regehr, W.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.