Expression of multiple UNC-13 proteins in the Caenorhabditis elegans nervous system

Molecular Biology of the Cell

Volumn 11, Issue 10, 2000, Pages 3441-3452

  Kohn, R E ^a   Duerr, J S ^a   McManus, J R ^a   Duke, A ^a   Rakow, T L ^a   Maruyama, H ^a   Moulder, G ^a   Maruyama, I N ^a   Barstead, R J ^a   Rand, J B ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN;

ANIMAL BEHAVIOR; ARTICLE; CAENORHABDITIS ELEGANS; DELETION MUTANT; GENE LOSS; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; NERVOUS SYSTEM; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

CAENORHABDITIS ELEGANS;

EID: 0033790323     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.10.3441     Document Type: Article

References (48)

1. The Caenorhabditis elegans unc-13 gene product is a phospholipid-dependent high-affinity phorbol ester receptor
2. The Caenorhabditis elegans unc-17 gene: A putative vesicular acetylcholine transporter
3. Reverse genetics
4. Munc13-c11 is a presynaptic phorbol ester receptor that enhances neurotransmitter release
5. The genetics of Caenorhabditis elegans
6. 2-domain proteins
7. Protein kinase C contains two phorbol ester binding domains
8. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways
9. 2+/phospholipid binding
10. The cat-1 gene of C. elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors
11. UNC-13 in the C. elegans nervous system
12. Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans
13. Interaction of synaptotagmin with the cytoplasmic domains of neurexins
14. Synaptic vesicle membrane fusion complex: Action of clostridial neurotxin on assembly
15. Spontaneous mutations of trichlorfon resistance in the nematode Caenorhabditis elegans
16. The acetylcholinesterase genes of C. elegans: Identification of a third gene (ace-3) and mosaic mapping of a synthetic lethal phenotype
17. Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C
18. Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor: Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity
19. Facilitation of synaptic transmission by EGL-30 G(q)α and EGL-8 PLCβ: DAG binding to UNC-13 is required to stimulate acetylcholine release
20. 2+ sensors for the fast and slow components of neurotransmitter release
21. Restriction endonuclease fingerprinting (REF): A sensitive method for screening mutations in long, contiguous segments of DNA
22. A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans
23. cRACE: A simple method for identification of the 5' end of mRNAs
24. Identification and characterization of the vesicular GABA transporter
25. The effects of translocations on recombination frequency in Caenorhabditis elegans
26. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
27. A genetic selection for Caenorhabditis elegans synaptic transmission mutants
28. G(o)α and diacylglycerol kinase negatively regulate the G(q)α pathway in C. elegans
29. Identification and intracellular localization of the unc-22 gene product of Caenorhabditis elegans
30. Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase
31. Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin
32. Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants
33. Serotonin inhibition of synaptic transmission: Gα(o) decreases the abundance of UNC-13 at release sites
34. Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion
35. 2+-dependent exocytotic machinery
36. The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein
37. Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C
38. Molecular basis of drug-resistance mutations in the nematode Caenorhabditis elegans
39. UNC-13 is required for synaptic vesicle fusion in C. elegans
40. Regulation of the UNC-18-Caenorhabditis degans syntaxin complex by UNC-13
41. Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: Application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots
42. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
43. SNAP receptors implicated in vesicle targeting and fusion
44. Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia
45. A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites
46. Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling