Drug silica nanocomposite: Preparation, characterization and skin permeation studies

Pharmaceutical Development and Technology

Volumn 18, Issue 3, 2013, Pages 626-633

  Pilloni, Martina ^a   Ennas, Guido ^a   Casu, Mariano ^a   Fadda, Anna Maria ^a   Frongia, Francesca ^a   Marongiu, Francesca ^a   Sanna, Roberta ^a   Scano, Alessandra ^b   Valenti, Donatella ^a   Sinico, Chiara ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b AIN   (Spain)

Author keywords

Ball milling; Caffeine; Drug release; Nanocomposite; Silica matrix

Indexed keywords

CAFFEINE; NANOCOMPOSITE; SILICON DIOXIDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG PENETRATION; DRUG RELEASE; DRUG STRUCTURE; GRINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INFRARED SPECTROSCOPY; NEWBORN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCANNING ELECTRON MICROSCOPY; SOLID STATE; SWINE; TRANSMISSION ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION;

ANIMALS; ANIMALS, NEWBORN; CHEMISTRY, PHARMACEUTICAL; NANOCOMPOSITES; ORGAN CULTURE TECHNIQUES; SILICON DIOXIDE; SKIN; SKIN ABSORPTION; SWINE;

EID: 84881567160     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2011.653821     Document Type: Article

References (23)

1. Slowing II, Vivero-Escoto JL, Wu CW, Lin VS. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev 2008;60:1278-1288.
2. Meseguer-Olmo L, Ros-Nicolás M, Vicente-Ortega V, Alcaraz-Baños M, Clavel-Sainz M, Arcos D et al. A bioactive sol-gel glass implant for in vivo gentamicin release. Experimental model in Rabbit. J Orthop Res 2006;24:454-460.
3. Radin S, El-Bassyouni G, Vresilovic EJ, Schepers E, Ducheyne P. In vivo tissue response to resorbable silica xerogels as controlledrelease materials. Biomaterials 2005;26:1043-1052.
4. Arruebo M, Galan M, Navascues N, Tellez C, Marquina C, Ibarra MR, Santamaria J. Development of magnetic nanostructured silicabased materials as potential vectors for drug-delivery applications. Chem Mater 2006;18:1911-1919.
5. Ahola M, Kortesuo P, Kangasniemi I, Kiesvaara J, Yli-Urpo A. Silica xerogel carrier material for controlled release of toremifene citrate. Int J Pharm 2000;195:219-227.
6. Charnaya C, Bégua S, Tourné-Péteilha C, Nicolea L, Lernera DA, Devoisselle JM. Inclusion of ibuprofen in mesoporous template silica: drug loading and release property. Eur J Pharm Biopharm 2004;57:533-540.
7. Descamps M, Willart JF, Dudognon E, Caron V. Transformation of pharmaceutical compounds upon milling and comilling: the role of T(g). J Pharm Sci 2007;96:1398-1407.
8. Manca ML, Zaru M, Ennas G, Valenti D, Sinico C, Loy G et al. Diclofenac-beta-cyclodextrin binary systems: physicochemical characterization and in vitro dissolution and diffusion studies. AAPS PharmSciTech 2005;6:E464-E472.
9. Wongmekiat A, Yoshimatsu S, Tozuka Y, Moribe K, Yamamoto K. Investigation of drug nanoparticle formation by co-grinding with cyclodextrins: studies for Indomethacin, Furosemide and Naproxen. J Incl Phen and Macr Chem 2006;56:29-32.
10. Fukami T, Ishii T, Io T, Suzuki N, Suzuki T, Yamamoto K et al. Nanoparticle processing in the solid state dramatically increases the cell membrane permeation of a cholesterol-lowering drug, probucol. Mol Pharm 2009;6:1029-1035.
11. Amato M, Isenschmid M, Hüppi P. Percutaneous caffeine application in the treatment of neonatal apnoea. Eur J Pediatr 1991;150:592-594.
12. Nicoli S, Colombo P, Santi P. Release and permeation kinetics of caffeine from bioadhesive transdermal films. AAPS J 2005;7:E218-E223.
13. Sinico C, Manconi M, Peppi M, Lai F, Valenti D, Fadda AM. Liposomes as carriers for dermal delivery of tretinoin: in vitro evaluation of drug permeation and vesicle-skin interaction. J Control Release 2005;103:123-136.
14. Sutor DJ. The structures of the pyrimidines and purines. VI. The crystal structure of theophylline. Act Cryst 1958;11:83-87.
15. Gunasekaran S, Sankari G, Ponnusamy S. Vibrational spectral investigation on xanthine and its derivatives-theophylline, caffeine and theobromine. Spectrochim Acta A Mol Biomol Spectrosc 2005;61:117-127.
16. Lipmaa E, Magi M, Samoson A, Engelhardt G, Grimmer AR. Structural studies of silicates by solid-state high-resolution 29Si NMR. J Am Chem Soc 1980;102:4889-4893.
17. Cannas C, Casu M, Musinu A, Lai A, Piccaluga G. XRD, TEM and 29Si MAS NMR study of sol-gel ZnO-SiO2 nanocomposites. J Mater Chem 1999;9:1765-1769.
18. Cannas C, Casu M, Lai A, Musinu A, Piccaluga G. Study of the nanoparticle/matrix interactions in Y2O3-SiO2 samples. Phys Chem Chem Phys 2002;4:2286-2292.
19. Engelhardt G. High Resolution Solid State NMR of Silicates and Zeolites. New York, NY: John Wiley and Sons, 1987.
20. Maciel GE, Sindorf DW. Silicon-29 NMR study of the surface of silica gel by cross polarization and magic-angle spinning. J Am Chem Soc 1980;102:7606-7607.
21. Sindorf DW, Maciel GE. Silicon-29 CP/MAS NMR studies of methylchlorosilane reactions on silica gel. J Am Chem Soc 1981;103:4263-4265.
22. Zumbulyadis N,O'Reilly JM. Polarization transfer across interfaces. 1. 29Si Cross-Polarization dynamics at the poly(vinyl alcohol)-silica sol-gel interface. Macr 1991;24:5294-5298.
23. Simonutti R, Comotti A, Neuroni F, Sozzani P. 13C and 29Si Solid-State NMR of rubber-silica composite materials. Chem Mater 1999;11:822-828.