Cytomegalovirus viraemia in HIV exposed and infected infants: Prevalence and clinical utility for diagnosing CMV pneumonia

Journal of Clinical Virology

Volumn 58, Issue 1, 2013, Pages 74-78

  Hsiao, Nei Yuan ^a   Zampoli, Marco ^a   Morrow, Brenda ^a   Zar, Heather J ^a   Hardie, Diana ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Cytomegalovirus; HIV; Infant; Opportunistic infection; Pneumonia; Quantitative PCR

Indexed keywords

ARTICLE; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CYTOMEGALOVIRUS PNEUMONIA; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SOUTH AFRICA; VIREMIA; VIRUS LOAD;

EID: 84881551170     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2013.05.002     Document Type: Article

References (25)

1. Kaye S., Miles D., Antoine P., Burny W., Ojuola B., Kaye P., et al. Virological and immunological correlates of mother-to-child transmission of cytomegalovirus in The Gambia. J Infect Dis 2008, 197(May (9)):1307-1314.
2. Ikeogu M.O., Wolf B., Mathe S. Pulmonary manifestations in HIV seropositivity and malnutrition in Zimbabwe. Arch Dis Child 1997, 76(February (2)):124-128.
3. Jeena P.M., Coovadia H.M., Chrystal V. Pneumocystis carinii and cytomegalovirus infections in severely ill, HIV-infected African infants. Ann Trop Paediatr 1996, 16(December (4)):361-368.
4. Weinberg A., Duarte M.I. Respiratory complications in Brazilian patients infected with human immunodeficiency virus. Rev Inst Med Trop Sao Paulo 1993, 35(March (2)):129-139.
5. Chintu C., Mudenda V., Lucas S., Nunn A., Lishimpi K., Maswahu D., et al. Lung diseases at necropsy in African children dying from respiratory illnesses: a descriptive necropsy study. Lancet 2002, 360(September (9338)):985-990.
6. Goussard P., Kling S., Gie R.P., Nel E.D., Heyns L., Rossouw G.J., et al. CMV pneumonia in HIV-infected ventilated infants. Pediatr Pulmonol 2010, 45(July 7):650-655.
7. Kitchen B.J., Engler H.D., Gill V.J., Marshall D., Steinberg S.M., Pizzo P.A., et al. Cytomegalovirus infection in children with human immunodeficiency virus infection. Pediatr Infect Dis J 1997, 16(April (4)):358-363.
8. Zampoli M., Morrow B., Hsiao N.Y., Whitelaw A., Zar H.J. Prevalence and outcome of cytomegalovirus-associated pneumonia in relation to human immunodeficiency virus infection. Pediatr Infect Dis J 2011, 30(May (5)):413-417.
9. Costa C., Libertucci D., Solidoro P., Sinesi F., Bergallo M., Margio S., et al. Rapid shell vial culture for the detection of respiratory viruses from bronchoalveolar lavage in immunocompromised patients. Panminerva Med 2007, 49(March (1)):1-6.
10. Angelici E., Contini C., Sebastiani G., Folgori F., Delia S., Serra P., et al. Cytomegalovirus in bronchoalveolar lavage specimens from patients with AIDS: comparison with antigenaemia and viraemia. J Med Microbiol 1996, 45(August (2)):149-152.
11. Kovacs A., Schluchter M., Easley K., Demmler G., Shearer W., La Russa P., et al. Cytomegalovirus infection and HIV-1 disease progression in infants born to HIV-1-infected women. Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection Study Group. N Engl J Med 1999, 341(July (2)):77-84.
12. Uberti-Foppa C., Lillo F., Terreni M.R., Puglisi A., Guffanti M., Gianotti N., et al. Cytomegalovirus pneumonia in AIDS patients: value of cytomegalovirus culture from BAL fluid and correlation with lung disease. Chest 1998, 113(April (4)):919-923.
13. Mann M., Shelhamer J.H., Masur H., Gill V.J., Travis W., Solomon D., et al. Lack of clinical utility of bronchoalveolar lavage cultures for cytomegalovirus in HIV infection. Am J Respir Crit Care Med 1997, 155(May (5)):1723-1728.
14. Razonable R.R., Emery V.C. Management of CMV infection and disease in transplant patients. 27-29 February 2004. Herpes 2004, 11(December (3)):77-86.
15. Morrow B.M., Hsaio N.Y., Zampoli M., Whitelaw A., Zar H.J. Pneumocystis pneumonia in South African children with and without human immunodeficiency virus infection in the era of highly active antiretroviral therapy. Pediatr Infect Dis J 2010, 29(June (6)):535-539.
16. Marin Gabriel M.A., Ramos Amador J.T., Gonzalez T.M., Rojo C.P., Saavedra L.J., de la Cruz B.J. Cytomegalovirus infection in the first year of life in human immunodeficiency virus-infected children: impact on survival and progression of the HIV disease. Med Sci Monit 2007, 13(April (4)):CR177-CR181.
17. Doyle M., Atkins J.T., Rivera-Matos I.R. Congenital cytomegalovirus infection in infants infected with human immunodeficiency virus type 1. Pediatr Infect Dis J 1996, 15(December (12)):1102-1106.
18. Nigro G., Krzysztofiak A., Gattinara G.C., Mango T., Mazzocco M., Porcaro M.A., et al. Rapid progression of HIV disease in children with cytomegalovirus DNAemia. AIDS 1996, 10(September (10)):1127-1133.
19. Slyker J.A., Rowland-Jones S.L., Dong T., Reilly M., Richardson B., Emery V.C., et al. Acute cytomegalovirus infection is associated with increased frequencies of activated and apoptosis-vulnerable T cells in HIV-1-infected infants. J Virol 2012, 86:11373-11379.
20. McNally L.M., Jeena P.M., Gajee K., Thula S.A., Sturm A.W., Cassol S., et al. Effect of age, polymicrobial disease, and maternal HIV status on treatment response and cause of severe pneumonia in South African children: a prospective descriptive study. Lancet 2007, 369(April (9571)):1440-1451.
21. Slyker J.A., Lohman-Payne B.L., John-Stewart G.C., Maleche-Obimbo E., Emery S., Richardson B., et al. Acute cytomegalovirus infection in Kenyan HIV-infected infants. AIDS 2009, 23(October (16)):2173-2181.
22. Limaye A.P., Kirby K.A., Rubenfeld G.D., Leisenring W.M., Bulger E.M., Neff M.J., et al. Cytomegalovirus reactivation in critically ill immunocompetent patients. JAMA 2008, 300(July (4)):413-422.
23. Griffin E., Krantz E., Selke S., Huang M.L., Wald A. Oral mucosal reactivation rates of herpesviruses among HIV-1 seropositive persons. J Med Virol 2008, 80(July (7)):1153-1159.
24. Cope A.V., Sabin C., Burroughs A., Rolles K., Griffiths P.D., Emery V.C. Interrelationships among quantity of human cytomegalovirus (HCMV) DNA in blood, donor-recipient serostatus, and administration of methylprednisolone as risk factors for HCMV disease following liver transplantation. J Infect Dis 1997, 176(December (6)):1484-1490.
25. Emery V.C., Sabin C.A., Cope A.V., Gor D., Hassan-Walker A.F., Griffiths P.D. Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation. Lancet 2000, 355(June (9220)):2032-2036.