Lack of clinical utility of bronchoalveolar lavage cultures for cytomegalovirus in HIV infection

American Journal of Respiratory and Critical Care Medicine

Volumn 155, Issue 5, 1997, Pages 1723-1728

  Mann, Marianne ^b   Shelhamer, James H ^b   Masur, Henry ^b   Gill, Vee J ^b   Travis, William ^b   Solomon, Diane ^b   Manischewitz, Jody ^b   Stock, Frida ^b   Lane, H Clifford ^b   Ognibene, Frederick P ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANTIGEN DETECTION; ARTICLE; BRONCHOSCOPY; CLINICAL PROTOCOL; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LUNG LAVAGE; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETINITIS; TRANSBRONCHIAL BIOPSY; VIRUS CULTURE; VIRUS DETECTION;

EID: 8244235757     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.155.5.9154883     Document Type: Article

References (28)

1. Zurlo, J., D. O'Neill, M. Polis, J. Manischewitz, R. Yarchoan, M. Baseler, H. C. Lane, and H. Masur. 1993. Lack of clinical utility of cytomegalovirus blood and urine cultures in patients with HIV infection. Ann. Intern. Med. 118:12-17.
2. McKenzie, R., W. D. Travis, S. A. Dolan, S. Pittaluga, I. M. Feuerstein, J. Shelhamer, R. Yarchoan, and H. Masur. 1991. The causes of death in patients with human immunodeficiency virus infection: a clinical and pathologic study with emphasis on the role of pulmonary disease. Medicine 70:326-342.
3. Jensen, A. B., J. D. Lundgren, T. Benfield, T. L. Nielsen, and J. Vestbo. 1995. Does cytomegalovirus predict a poor outcome in Pneumocystis carinii pneumonia treated with corticosteroids? Chest 108:411-414.
4. Stover, D. E., M. B. Zaman, S. I. Hajdu, M. Lange, J. Gold, and D. Armstrong. 1984. Bronchoalveolar lavage in the diagnosis of diffuse pulmonary infiltrates in the immunosuppressed host. Ann. Intern. Med. 101:1-7.
5. Springmeyer, S. C., R. C. Hackman, R. Holle, G. M. Greenberg, C. E. Weems, D. Myerson, J. D. Meyers, and E. D. Thomas. 1986. Use of bronchoalveolar lavage to diagnose acute diffuse pneumonia in the immunocompromised host. J. Infect. Dis. 154:604-610.
6. Drew, W. L. 1988. Diagnosis of cytomegalovirus infection. Rev. Infect. Dis. 10(Suppl. 3):2468-2476.
7. Ruutu, P., T. Ruutu, L. Volin, P. Tukiainen, P. Ukkonen, and T. Hovi. 1990. Cytomegalovirus is frequently isolated in bronchoalveolar lavage fluid of bone marrow transplant recipients without pneumonia. Ann. Intern. Med. 112:913-916.
8. Murray, J. F., C. P. Felton, S. M. Garay, M. S. Gottlieb, P. C. Hopewell, D. E. Stover, and A. S. Teirstein. 1984. Pulmonary complications of the acquired immunodeficiency syndrome: report of a National Heart, Lung and Blood Institute workshop. N. Engl. J. Med. 310:1682-1688.
9. Bower, M., S. E. Barton, M. R. Nelson, J. Bobby, D. Smith, M. Youle, and B. G. Gazzard. 1990. The significance of the detection of cytomegalovirus in the bronchoalveolar lavage fluid in AIDS patients with pneumonia. AIDS 4:317-320.
10. Jacobson, M. A., J. Mills, J. Rush, L. Peiperl, V. Seru, P. K. Mohanty, P. C. Hopewell, W. K. Hadley, V. C. Broadus, and G. Leoung. 1991. Morbidity and mortality of patients with AIDS in the first-episode Pneumocystis carinii pneumonia unaffected by concomitant pulmonary cytomegalovirus infection. Am. Rev. Respir. Dis. 144:6-9.
11. Hayner, C. E., R. P. Baughman, C. C. Linnemann, and M. N. Dohn. 1995. The relationship between cytomegalovirus by bronchoalveolar lavage and mortality in patients with HIV. Chest 107:735-740.
12. Polis, M. A., M. D. DeSmet, B. F. Baird, S. D. Mellow, J. Falloon, R. T. Davey, Jr., J. A. Kovacs, A. G. Palestine, R. B. Nusenblatt, and H. Masur. 1993. Increased survival of a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis who received sodium phosphonoformate (foscarnet). Am. J. Med. 94:175-180.
13. Ognibene F. P., J. H. Shelhamer, V. J. Gill, A. M. Macher, D. Loew, M. M. Parker, E. Gelmann, A. S. Fauci, J. E. Parrillo, and H. Masur. 1984. The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage. Am. Rev. Respir. Dis. 129:929-932.
14. Gosey, L. L., R. M. Howard, F. G. Witebsky, F. P. Ognibene, T. C. Wu, V. J. Gill, and J. D. MacLowry. 1985. Advantages of a modified toluidine blue O stain and bronchoalveolar lavage for the diagnosis of Pneumocystis carinii pneumonia. J. Clin. Microbiol. 22:803-807.
15. Gill, V. J., G. Evans, F. Stock, J. E. Parrillo, H. Masur, and J. A. Kovacs. 1987. Detection of Pneumocystis carinii by fluorescent-antibody stain using a combination of three monoclonal antibodies. J. Clin. Microbiol. 25:1837-1840.
16. Quinnan, G. V., H. Masur, A. H. Rook, G. Armstrong, W. R. Frederick, J. Epstein, J. F. Manishewitz, A. M. Macher, L. Jackson, and J. Ames. 1984. Herpes virus infections in the acquired immune deficiency syndrome. J.A.M.A. 252:72-80.
17. Suffredini, A. F., F. P. Ognibene, E. E. Lack, J. T. Simmons, M. Brenner, V. J. Gill, H. C. Lane, A. S. Fauci, J. E. Parrillo, and H. Masur. 1987. Nonspecific interstitial pneumonitis: a common cause of pulmonary disease in the acquired immunodeficiency syndrome. Ann. Intern. Med. 107:7-13.
18. Jacobson, M. A., and J. Mills. 1988. Serious cytomegalovirus disease in acquired immunodeficiency syndrome (AIDS). Ann. Intern. Med. 108: 585-594.
19. Millar, A. B., G. Patou, R. F. Miller, J. E. Grundy, D. R. Katz, I. V. Weller, and S. J. Semple. 1990. Cytomegalovirus in the lungs of patients with AIDS. Am. Rev. Respir. Dis. 141:1474-1477.
20. Ognibene, F. P., H. Masur, P. Rogers, W. D. Travis, A. F. Suffredini, I. Feuerstein, V. J. Gill, B. F. Baird, J. A. Carrasquillo, and J. E. Parillo. 1988. Nonspecific interstitial pneumonitis without evidence of Pneumocystis carinii in asymptomatic patients infected with human immunodeficiency virus (HIV). Ann. Intern. Med. 109:874-879.
21. Travis, W. D., C. H. Fox, K. O. Devaney, L. M. Weiss, T. J. O'Leary, F. P. Ognibene, A. F. Suffredini, M. J. Rosen, M. B. Cohen, and J. Shelhamer. 1992. Lymphoid pneumonitis in 50 adult patients infected with the human immunodeficiency virus: lymphocytic interstitial pneumonitis versus nonspecific interstitial pneumonitis. Hum. Pathol. 23:529-541.
22. Masur, H., F. P. Ognibene, R. Yarchoan, J. H. Shelhamer, B. F. Baird, W. Travis, A. F. Suffredini, L. Deyton, J. A. Kovacs, J. Falloon, R. Davey, M. Polis, J. Metcalf, M. Baseler, R. Wesley, V. J. Gill, A. S. Fauci, and H. C. Lane. 1989. CD4 counts as predictors of opportunistic pneumonias in human immuno-deficiency virus (HIV) infection. Ann. Intern. Med. 111:223-231.
23. Fajac, A., M. Vidaud, F. Lebargy, F. Stephan, S. Ricci, P. Geslin, M. Goosens, and J. F. Bernaudin. 1994. Evaluation of human cytomegalovirus latency in alveolar macrophages. Am. J. Respir. Crit. Care Med. 149:495-499.
24. Ng-Bautista, C. L., and D. D. Sedmak. 1995. Cytomegalovirus infection is associated with absence of alveolar epithelial HLA class II antigen expression. J.I.D. 171:39-44.
25. Cummington, A. C., D. S. Milne, J. Wilkes, J. H. Dark, T. D. Tetley, and J. A. Kirby. 1994. Constitutive expression of MHC and adhesion molecules by alveolar epithelial cells (type II pneumocytes) isolated from human lung and comparison with immunocytochemical findings. J. Cell. Sci. 107:443-449.
26. Schneeberger, E. E., M. DeFerran, M. J. Skoskiewicz, P. S. Russell, and R. B. Colvin. 1986. Induction of MHC-determined antigens in the lung by interferon-gamma. Lab. Invest. 55:138-144.
27. Grundy, J. E., J. D. Shanley, and P. D. Griffiths. 1988. Is cytomegalovirus pneumonitis in transplant patients an immunopathological condition? Lancet 2:996-999.
28. Aukrust, P., I. N. Farstad, S. S. Froland, and E. Holler. 1992. Cytomegalovirus (CMV) pneumonitis in AIDS patients: the result of intensive CMV replication? Eur. Respir. J. 4:362-364.