Immunophenotype of peripheral blood natural killer cells and IL-10 serum levels in relation to Helicobacter pylori status

APMIS

Volumn 121, Issue 9, 2013, Pages 806-813

  Rudnicka, Karolina ^a   Matusiak, Agnieszka ^a   Miszczyk, Eliza ^a   Rudnicka, Wieslawa ^a   Tenderenda, Michal ^b   Chmiela, Magdalena ^a  

^a UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

Author keywords

CD25; Helicobacter pylori; IL 10; cytotoxic activity; Lymphocytes; NK cells

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1;

ADULT; ARTICLE; CD25+ T LYMPHOCYTE; CD3+ T LYMPHOCYTE; CLINICAL ARTICLE; CYTOTOXICITY; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MALE; NATURAL KILLER CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

CD25; HELICOBACTER PYLORI; IL-10; CYTOTOXIC ACTIVITY; LYMPHOCYTES; NK CELLS;

ADULT; ANTIGENS, CD56; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION; GPI-LINKED PROTEINS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; RECEPTORS, IGG;

EID: 84881544571     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/apm.12120     Document Type: Article

References (45)

1. Vivier E, Tomasello E, Barafin M, Walzer T, Ugdini S. Functions of natural killer cells. Nat Immunol 2008;9:503-10.
2. Kapetanovic R, Cavaillon JM. Early events in innate immunity in recognition of microbial pathogens. Expert Opin Biol Ther 2007;7:907-18.
3. dim natural killer cell subsets respond differentially by direct stimulation with Mycobacterium bovis bacillary Calmette-Guerin. Scand J Immunol 2005;62:498-506.
4. Neuman KC, Riley EM. Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens. Nat Rev Immunol 2007;7:279-91.
5. Sun JC, Lanier LL. Natural killer cells remember: an evolutionary bridge between innate and adaptive immunity? Eur J Immunol 2009;39:2059.
6. Vivier E, Ugolini S. Natural killer cells: from basic research to treatments. Front Immunol 2011;2:1-4.
7. Caliguri MA. Human natural killer cells. Blood 2008;112:461-9.
8. Carrega P, Montalto E, Ferlazzo G. Identification of natural killer cells in tissues and their isolation. Lotze MT, Thomson AW editors. Natural killer cells. San Diego: Elsevier, 2010.
9. Berk G, Clark WR. Innate Cell-mediated Immunity in Killer Lymphocytes. Dordrecht, Netherlands: Springer, 2005.
10. Lunemann A, Lunemann JD, Munz C. Regulatory NK-cell functions in inflammation and autoimmunity. Mol Med 2009;15:352-8.
11. Baume DM, Robertson MJ, Levine H, Manley TJ, Schow PW, Ritz J. Differential responses to IL-2 define functionally distinct subsets of human natural killer cells. Eur J Immunol 1992;22:1-6.
12. Carson WE, Fehniger TA, Haldor S, Eckhert K, Lindermann MJ, Lai CF, et al. A potential role for IL-15 in the regulation of human natural killer cell survival. J Clin Invest 1997;99:937-43.
13. Wilk E, Kalippke K, Buyny S, Schmidt RE, Jacobs R. New aspects of NK cell subset identification and interference of NK cells' regulatory capacity by assessing functional and genomic profiles. Immunobiology 2008;213:271-83.
14. Scott MJ, Hoth JJ, Turina M, Woods DR, Cheadle WG. Interleukin - 10 suppress natural killer but not natural killer T cell activation during bacterial infection. Cytokine 2006;33:79-86.
15. Perona-Wright G, Mohrs K, Szaba FM, Kummer LW, Madan R, Karp CL, et al. Systemic but not local infections elicit immunosuppressive IL-10 by human natural killer cells stimulated with IL-2 and/or IL-12. J Immunol 2009;160:2637-44.
16. Chaushu S, Wiolensky A, Gur C, Ahapira L, Elboim M, Halfek G, et al. Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor Nkp46 aggravates periodontal disease. PLoS Pathog 2012;8:e1002601. doi: 10.1371/journal.ppat. 1002601
17. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984;341:1311-5.
18. Cover T, Blaser MJ. H. pylori in health and disease. Gastroenterology 2009;136:1863-73.
19. Chmiela M, Michetti P. Inflammation, immunity, vaccines for Helicobacter infection. Helicobacter 2006;11:21-6.
20. Yun CH, Lungren A, Azem J, Sjoling A, Holmgren J, Svennerholm A-M, et al. Natural Killer and Helicobacter pylori infection: bacterial antigens and IL-12 act synergistically to induce gamma interferon production. Infect Immun 2005;73:1482-90.
21. Chmiela M, Czkwianianc E, Wadstrom T, Rudnicka W. Role of Helicobacter pylori surface structures in bacterial interaction with macrophages. Gut 1997;40:20-4.
22. Paziak-Domańska B, Chmiela M, Jarosińska A, Rudnicka W. Potential role of CagA in the inhibition of T cell reactivity in Helicobacter pylori infections. Cell Immunol 2000;202:136-9.
23. Sundrud MS, Torres VJ, Unutzman D, Cover TL. Inhibition of primary human T cell proliferation by H. pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. PNAS 2004;101:7727-32.
24. Allen LAM. Phagocytosis and persistence of Helicobacter pylori. Cell Microbiol 2007;9:817-28.
25. Grebowska A, Moran AP, Bielański W, Matu-siak A, Rechciński T, Rudnicka K, et al. Helicobacter pylori lipopolysaccharide activity in human peripheral blood mononuclear leukocyte cultures. J Physiol Pharmacol 2010;4:437-42.
26. Rudnicka K, Wlodarczyk M, Moran AP, Rechciński T, Miszczyk E, Matusiak A, et al. Helicobacter pylori antigens as potential modulators of lymphocytes' cytotoxic activity. Microbiol Immunol 2012;56:62-75.
27. 13C-urea in the diagnostics of H. pylori infection. J Physiol Pharmacol 1996;47:545-53.
28. Rechciński T, Chmiela M, Malecka-Panas E, Planeta-Malecka I, et al. Serological indicators of H. pylori infection in adult dyspeptic patients and health blood donors. Microbiol Immunol 1997;41:387-93.
29. Vassilakopoulos TP, Nadali G, Angelopoulou MK, Siakantaris MP, Dimopoulou MN, Kontopidou FN, et al. Serum interleukin-10 levels are on independent prognostic factor for patients with Hodgkin's lymphoma. Haematologica 2001;86:274-81.
30. Nemunaitis J, Fong T, Shabe P, Martineau D, Ando D. Comparison of serum interleukin-10 (IL-10) levels between normal volunteers and patients with advanced melanoma. Cancer Invest 2001;19:239-47.
31. Myśliwska J, Zorena K, Semetkowska-Jurkiewicz E, Rachoń D, Suchanek H, Myśliwski A. High levels of circulating interleukin-10 in diabetic nephropathy patients. Eur Cytokine Netw 2005;16:117-22.
32. Szkaradkiewicz A, Karpiński TM, Drews M, Borejsza-Wysocki M, Majewski P, Andrzejewska E. Natural killer cell cytotoxicity and immunosuppressive cytokines (IL-10, TGF-β1) in patients with gastric cancer. J Biomed Biotechnol 2010;2010: doi: 10.1155/2010/901564
33. Lee SH, Kim KS, Fodil-Cornu N, Vidal SM, Biron CA. Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection. J Exp Med 2009;206:2235-51.
34. Axon A. Review article: gastric cancer and H. pylori. Aliment Pharmacol Ther 2002;16:83-8.
35. Hatakeyama M. Helicobacter pylori CagA-a potential bacterial oncoprotein that functionally mimics the mammalian Gab family of adaptor proteins. Microbes Infect 2002;5:143-50.
36. Hajishengallis G, Lambris JD. Microbial manipulation of receptor crosstalk in innate immunity. Nat Rev Immunol 2011;11:187-200.
37. Petersson M, Charo J, Salazar-Onfray F, Noffz G, Mohaupt M, Qin Z, et al. Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10. J Immunol 1997;161:2099-105.
38. Appelmelk BJ, Shiberu B, Trinks C, Tapsi N, Zheng PY, Verboom T. Phase variation in Helicobacter pylori lipopolysaccharide. Infect Immun 1998;66:70-6.
39. Miszczyk E, Rudnicka K, Moran AP, Fol M, Kowalewicz-Kulbat M, Druszczyńska M, et al. Interaction of Helicobacter pylori with C-type lectin dendritic cell-specific ICAM grabbing nonintegrin. J Biomed Biotechnol 2012;2012:206463. doi: 10.1155/2012/206463
40. Trinchieri G. Interleukin-10 production by effector T cells: Th1 cells show self control. J Exp Med 2007;204:239-43.
41. Lindgren A, Yun CH, Lundgren A, Sjoling A, Ohman L, Svennerholm AM, et al. CD8- natural killer cells are greatly enriched in the human gastrointestinal tract and have the capacity to respond to bacteria. J Innate Immun 2010;21:294-302.
42. Tarkkanen J, Kosunen TU, Sakela E. Contact of lymphocytes with Helicobacter pylori augments natural killer cell activity and induces production of IFN-γ. Infect Immun 1993;61:3012-6.
43. bright subset. Blood 2001;12:3146-51.
44. Tanaka TF, Kitamura Y, Nagasaka K, Kuida K, Suwa H, Miyasaka M. Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor β chain monoclonal antibody in mice. J Exp Med 1993;178:1103-7.
45. Souza-Fonseca-Guimaraes F, Adib-Conquy M, Cavaillon JM. Natural killer (NK) cells in antibacterial innate immunity: angels or devils? Mol Med 2012; 18: 270-85.